Real‐time refinement of subthalamic nucleus targeting using Bayesian decision‐making on the root mean square measure
Identifieur interne : 000B20 ( Istex/Curation ); précédent : 000B19; suivant : 000B21Real‐time refinement of subthalamic nucleus targeting using Bayesian decision‐making on the root mean square measure
Auteurs : Anan Moran [Israël] ; Izhar Bar-Gad [Israël] ; Hagai Bergman [Israël] ; Zvi Israel [Israël]Source :
- Movement Disorders [ 0885-3185 ] ; 2006-09.
English descriptors
- KwdEn :
Abstract
The subthalamic nucleus (STN) is a major target for treatment of advanced Parkinson's disease patients undergoing deep brain stimulation surgery. Microelectrode recording (MER) is used in many cases to identify the target nucleus. A real‐time procedure for identifying the entry and exit points of the STN would improve the outcome of this targeting procedure. We used the normalized root mean square (NRMS) of a short (5 seconds) MER sampled signal and the estimated anatomical distance to target (EDT) as the basis for this procedure. Electrode tip location was defined intraoperatively by an expert neurophysiologist to be before, within, or after the STN. Data from 46 trajectories of 27 patients were used to calculate the Bayesian posterior probability of being in each of these locations, given RMS‐EDT pair values. We tested our predictions on each trajectory using a bootstrapping technique, with the rest of the trajectories serving as a training set and found the error in predicting the STN entry to be (mean ± SD) 0.18 ± 0.84, and 0.50 ± 0.59 mm for STN exit point, which yields a 0.30 ± 0.28 mm deviation from the expert's target center. The simplicity and computational ease of RMS calculation, its spike sorting‐independent nature and tolerance to electrode parameters of this Bayesian predictor, can lead directly to the development of a fully automated intraoperative physiological procedure for the refinement of imaging estimates of STN borders. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.20995
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000B20
Links to Exploration step
ISTEX:F649E9403505138A799145593BAAF884D378A715Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Real‐time refinement of subthalamic nucleus targeting using Bayesian decision‐making on the root mean square measure</title><author><name sortKey="Moran, Anan" sort="Moran, Anan" uniqKey="Moran A" first="Anan" last="Moran">Anan Moran</name><affiliation wicri:level="1"><mods:affiliation>Gonda Multidisciplinary Brain Research Center and Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Israel</mods:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Gonda Multidisciplinary Brain Research Center and Faculty of Life Sciences, Bar Ilan University, Ramat Gan</wicri:regionArea></affiliation></author><author><name sortKey="Bar Ad, Izhar" sort="Bar Ad, Izhar" uniqKey="Bar Ad I" first="Izhar" last="Bar-Gad">Izhar Bar-Gad</name><affiliation wicri:level="1"><mods:affiliation>Gonda Multidisciplinary Brain Research Center and Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Israel</mods:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Gonda Multidisciplinary Brain Research Center and Faculty of Life Sciences, Bar Ilan University, Ramat Gan</wicri:regionArea></affiliation></author><author><name sortKey="Bergman, Hagai" sort="Bergman, Hagai" uniqKey="Bergman H" first="Hagai" last="Bergman">Hagai Bergman</name><affiliation wicri:level="1"><mods:affiliation>Department of Physiology, Hadassah Medical School and Interdisciplinary Center for Neural Computation, Hebrew University, Jerusalem, Israel</mods:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Physiology, Hadassah Medical School and Interdisciplinary Center for Neural Computation, Hebrew University, Jerusalem</wicri:regionArea></affiliation></author><author><name sortKey="Israel, Zvi" sort="Israel, Zvi" uniqKey="Israel Z" first="Zvi" last="Israel">Zvi Israel</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurosurgery, Hadassah University Hospital, Jerusalem, Israel</mods:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurosurgery, Hadassah University Hospital, Jerusalem</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:F649E9403505138A799145593BAAF884D378A715</idno><date when="2006" year="2006">2006</date><idno type="doi">10.1002/mds.20995</idno><idno type="url">https://api.istex.fr/document/F649E9403505138A799145593BAAF884D378A715/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000B20</idno><idno type="wicri:Area/Istex/Curation">000B20</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Real‐time refinement of subthalamic nucleus targeting using Bayesian decision‐making on the root mean square measure</title><author><name sortKey="Moran, Anan" sort="Moran, Anan" uniqKey="Moran A" first="Anan" last="Moran">Anan Moran</name><affiliation wicri:level="1"><mods:affiliation>Gonda Multidisciplinary Brain Research Center and Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Israel</mods:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Gonda Multidisciplinary Brain Research Center and Faculty of Life Sciences, Bar Ilan University, Ramat Gan</wicri:regionArea></affiliation></author><author><name sortKey="Bar Ad, Izhar" sort="Bar Ad, Izhar" uniqKey="Bar Ad I" first="Izhar" last="Bar-Gad">Izhar Bar-Gad</name><affiliation wicri:level="1"><mods:affiliation>Gonda Multidisciplinary Brain Research Center and Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Israel</mods:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Gonda Multidisciplinary Brain Research Center and Faculty of Life Sciences, Bar Ilan University, Ramat Gan</wicri:regionArea></affiliation></author><author><name sortKey="Bergman, Hagai" sort="Bergman, Hagai" uniqKey="Bergman H" first="Hagai" last="Bergman">Hagai Bergman</name><affiliation wicri:level="1"><mods:affiliation>Department of Physiology, Hadassah Medical School and Interdisciplinary Center for Neural Computation, Hebrew University, Jerusalem, Israel</mods:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Physiology, Hadassah Medical School and Interdisciplinary Center for Neural Computation, Hebrew University, Jerusalem</wicri:regionArea></affiliation></author><author><name sortKey="Israel, Zvi" sort="Israel, Zvi" uniqKey="Israel Z" first="Zvi" last="Israel">Zvi Israel</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurosurgery, Hadassah University Hospital, Jerusalem, Israel</mods:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurosurgery, Hadassah University Hospital, Jerusalem</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2006-09">2006-09</date><biblScope unit="vol">21</biblScope><biblScope unit="issue">9</biblScope><biblScope unit="page" from="1425">1425</biblScope><biblScope unit="page" to="1431">1431</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">F649E9403505138A799145593BAAF884D378A715</idno><idno type="DOI">10.1002/mds.20995</idno><idno type="ArticleID">MDS20995</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Bayesian inference</term><term>Parkinson's disease</term><term>deep brain stimulation</term><term>microelectrode recording</term><term>root mean square</term><term>target localization</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The subthalamic nucleus (STN) is a major target for treatment of advanced Parkinson's disease patients undergoing deep brain stimulation surgery. Microelectrode recording (MER) is used in many cases to identify the target nucleus. A real‐time procedure for identifying the entry and exit points of the STN would improve the outcome of this targeting procedure. We used the normalized root mean square (NRMS) of a short (5 seconds) MER sampled signal and the estimated anatomical distance to target (EDT) as the basis for this procedure. Electrode tip location was defined intraoperatively by an expert neurophysiologist to be before, within, or after the STN. Data from 46 trajectories of 27 patients were used to calculate the Bayesian posterior probability of being in each of these locations, given RMS‐EDT pair values. We tested our predictions on each trajectory using a bootstrapping technique, with the rest of the trajectories serving as a training set and found the error in predicting the STN entry to be (mean ± SD) 0.18 ± 0.84, and 0.50 ± 0.59 mm for STN exit point, which yields a 0.30 ± 0.28 mm deviation from the expert's target center. The simplicity and computational ease of RMS calculation, its spike sorting‐independent nature and tolerance to electrode parameters of this Bayesian predictor, can lead directly to the development of a fully automated intraoperative physiological procedure for the refinement of imaging estimates of STN borders. © 2006 Movement Disorder Society</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000B20 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 000B20 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Istex
|étape= Curation
|type= RBID
|clé= ISTEX:F649E9403505138A799145593BAAF884D378A715
|texte= Real‐time refinement of subthalamic nucleus targeting using Bayesian decision‐making on the root mean square measure
}}
| This area was generated with Dilib version V0.6.23. |  |