Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results
Identifieur interne : 000660 ( Istex/Curation ); précédent : 000659; suivant : 000661Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results
Auteurs : Christopher G. Goetz [États-Unis] ; Barbara C. Tilley [États-Unis] ; Stephanie R. Shaftman [États-Unis] ; Glenn T. Stebbins [États-Unis] ; Stanley Fahn [États-Unis] ; Pablo Martinez-Martin [Espagne] ; Werner Poewe [Autriche] ; Cristina Sampaio [Portugal] ; Matthew B. Stern [États-Unis] ; Richard Dodel [Allemagne] ; Bruno Dubois [France] ; Robert Holloway [États-Unis] ; Joseph Jankovic [États-Unis] ; Jaime Kulisevsky [Espagne] ; Anthony E. Lang [Canada] ; Andrew Lees [Royaume-Uni] ; Sue Leurgans [États-Unis] ; Peter A. Lewitt [États-Unis] ; David Nyenhuis [États-Unis] ; C. Warren Olanow [États-Unis] ; Olivier Rascol [France] ; Anette Schrag [Royaume-Uni] ; Jeanne A. Teresi [États-Unis] ; Jacobus J. Van Hilten [Pays-Bas] ; Nancy Lapelle [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-11-15.
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Abstract
We present a clinimetric assessment of the Movement Disorder Society (MDS)‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS). The MDS‐UDPRS Task Force revised and expanded the UPDRS using recommendations from a published critique. The MDS‐UPDRS has four parts, namely, I: Non‐motor Experiences of Daily Living; II: Motor Experiences of Daily Living; III: Motor Examination; IV: Motor Complications. Twenty questions are completed by the patient/caregiver. Item‐specific instructions and an appendix of complementary additional scales are provided. Movement disorder specialists and study coordinators administered the UPDRS (55 items) and MDS‐UPDRS (65 items) to 877 English speaking (78% non‐Latino Caucasian) patients with Parkinson's disease from 39 sites. We compared the two scales using correlative techniques and factor analysis. The MDS‐UPDRS showed high internal consistency (Cronbach's alpha = 0.79–0.93 across parts) and correlated with the original UPDRS (ρ = 0.96). MDS‐UPDRS across‐part correlations ranged from 0.22 to 0.66. Reliable factor structures for each part were obtained (comparative fit index > 0.90 for each part), which support the use of sum scores for each part in preference to a total score of all parts. The combined clinimetric results of this study support the validity of the MDS‐UPDRS for rating PD. © 2008 Movement Disorder Society
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DOI: 10.1002/mds.22340
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Lang</name><affiliation wicri:level="1"><mods:affiliation>Division of Neurology, University of Toronto, Toronto, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Neurology, University of Toronto, Toronto</wicri:regionArea></affiliation></author><author><name sortKey="Lees, Andrew" sort="Lees, Andrew" uniqKey="Lees A" first="Andrew" last="Lees">Andrew Lees</name><affiliation wicri:level="2"><mods:affiliation>Reta Lila Weston Institute of Neurological Studies, University College, London, England</mods:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Reta Lila Weston Institute of Neurological Studies, University College, London</wicri:cityArea></affiliation></author><author><name sortKey="Leurgans, Sue" sort="Leurgans, Sue" uniqKey="Leurgans S" first="Sue" last="Leurgans">Sue Leurgans</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Illinois</region></placeName><wicri:cityArea>Department of Neurological Sciences, Rush University Medical Center, Chicago</wicri:cityArea></affiliation></author><author><name sortKey="Lewitt, Peter A" sort="Lewitt, Peter A" uniqKey="Lewitt P" first="Peter A." last="Lewitt">Peter A. Lewitt</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurology, Wayne State University, Detroit, Michigan</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Michigan</region></placeName><wicri:cityArea>Department of Neurology, Wayne State University, Detroit</wicri:cityArea></affiliation></author><author><name sortKey="Nyenhuis, David" sort="Nyenhuis, David" uniqKey="Nyenhuis D" first="David" last="Nyenhuis">David Nyenhuis</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurology and Rehabilitation, University of Illinois, Chicago, Illinois</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Illinois</region></placeName><wicri:cityArea>Department of Neurology and Rehabilitation, University of Illinois, Chicago</wicri:cityArea></affiliation></author><author><name sortKey="Olanow, C Warren" sort="Olanow, C Warren" uniqKey="Olanow C" first="C. Warren" last="Olanow">C. Warren Olanow</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurology, Mount Sinai School of Medicine, New York, New York</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Neurology, Mount Sinai School of Medicine, New York</wicri:cityArea></affiliation><affiliation wicri:level="2"><mods:affiliation>Department of Neuroscience, Mount Sinai School of Medicine, New York, New York</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Neuroscience, Mount Sinai School of Medicine, New York</wicri:cityArea></affiliation></author><author><name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name><affiliation wicri:level="1"><mods:affiliation>Laboratoire de Pharmacologie Médicale et Clinique, Toulouse University, Toulouse, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Pharmacologie Médicale et Clinique, Toulouse University, Toulouse</wicri:regionArea></affiliation></author><author><name sortKey="Schrag, Anette" sort="Schrag, Anette" uniqKey="Schrag A" first="Anette" last="Schrag">Anette Schrag</name><affiliation wicri:level="2"><mods:affiliation>Department of Clinical Neurosciences, University College, London, England</mods:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Department of Clinical Neurosciences, University College, London</wicri:cityArea></affiliation></author><author><name sortKey="Teresi, Jeanne A" sort="Teresi, Jeanne A" uniqKey="Teresi J" first="Jeanne A." last="Teresi">Jeanne A. Teresi</name><affiliation wicri:level="2"><mods:affiliation>Stroud Center, Division of General Medicine and Psychiatric Institute, Columbia University, New York, New York</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Stroud Center, Division of General Medicine and Psychiatric Institute, Columbia University, New York</wicri:cityArea></affiliation></author><author><name sortKey="Van Hilten, Jacobus J" sort="Van Hilten, Jacobus J" uniqKey="Van Hilten J" first="Jacobus J." last="Van Hilten">Jacobus J. Van Hilten</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Leiden University, Leiden, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, Leiden University, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Lapelle, Nancy" sort="Lapelle, Nancy" uniqKey="Lapelle N" first="Nancy" last="Lapelle">Nancy Lapelle</name><affiliation wicri:level="2"><mods:affiliation>Division of Preventive and Behavioral Medicine, University of Massachusetts, Worcester, Massachusetts</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Preventive and Behavioral Medicine, University of Massachusetts, Worcester</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:20C8EC0AC3C3656D4CE380BDD9850EAC4AD525BA</idno><date when="2008" year="2008">2008</date><idno type="doi">10.1002/mds.22340</idno><idno type="url">https://api.istex.fr/document/20C8EC0AC3C3656D4CE380BDD9850EAC4AD525BA/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000660</idno><idno type="wicri:Area/Istex/Curation">000660</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results</title><author><name sortKey="Goetz, Christopher G" sort="Goetz, Christopher G" uniqKey="Goetz C" first="Christopher G." last="Goetz">Christopher G. Goetz</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Illinois</region></placeName><wicri:cityArea>Department of Neurological Sciences, Rush University Medical Center, Chicago</wicri:cityArea></affiliation></author><author><name sortKey="Tilley, Barbara C" sort="Tilley, Barbara C" uniqKey="Tilley B" first="Barbara C." last="Tilley">Barbara C. Tilley</name><affiliation wicri:level="2"><mods:affiliation>Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, South Carolina</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName><wicri:cityArea>Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston</wicri:cityArea></affiliation></author><author><name sortKey="Shaftman, Stephanie R" sort="Shaftman, Stephanie R" uniqKey="Shaftman S" first="Stephanie R." last="Shaftman">Stephanie R. Shaftman</name><affiliation wicri:level="2"><mods:affiliation>Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, South Carolina</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName><wicri:cityArea>Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston</wicri:cityArea></affiliation></author><author><name sortKey="Stebbins, Glenn T" sort="Stebbins, Glenn T" uniqKey="Stebbins G" first="Glenn T." last="Stebbins">Glenn T. Stebbins</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Illinois</region></placeName><wicri:cityArea>Department of Neurological Sciences, Rush University Medical Center, Chicago</wicri:cityArea></affiliation></author><author><name sortKey="Fahn, Stanley" sort="Fahn, Stanley" uniqKey="Fahn S" first="Stanley" last="Fahn">Stanley Fahn</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurology, Columbia University, New York, New York</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Neurology, Columbia University, New York</wicri:cityArea></affiliation></author><author><name sortKey="Martinez Artin, Pablo" sort="Martinez Artin, Pablo" uniqKey="Martinez Artin P" first="Pablo" last="Martinez-Martin">Pablo Martinez-Martin</name><affiliation wicri:level="1"><mods:affiliation>Neuroepidemiology Unit and CIBERNED, Carlos III Institute of Health, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Neuroepidemiology Unit and CIBERNED, Carlos III Institute of Health, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Innsbruck Medical University, Innsbruck, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, Innsbruck Medical University, Innsbruck</wicri:regionArea></affiliation></author><author><name sortKey="Sampaio, Cristina" sort="Sampaio, Cristina" uniqKey="Sampaio C" first="Cristina" last="Sampaio">Cristina Sampaio</name><affiliation wicri:level="1"><mods:affiliation>Department of Pharmacology, Faculdade de Medicina de Lisboa, Lisboa, Portugal</mods:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Department of Pharmacology, Faculdade de Medicina de Lisboa, Lisboa</wicri:regionArea></affiliation></author><author><name sortKey="Stern, Matthew B" sort="Stern, Matthew B" uniqKey="Stern M" first="Matthew B." last="Stern">Matthew B. Stern</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Department of Neurology, University of Pennsylvania, Philadelphia</wicri:cityArea></affiliation></author><author><name sortKey="Dodel, Richard" sort="Dodel, Richard" uniqKey="Dodel R" first="Richard" last="Dodel">Richard Dodel</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Philipps‐University, Marburg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Philipps‐University, Marburg</wicri:regionArea></affiliation></author><author><name sortKey="Dubois, Bruno" sort="Dubois, Bruno" uniqKey="Dubois B" first="Bruno" last="Dubois">Bruno Dubois</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Hôpital de la Salpêtrière, Paris, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology, Hôpital de la Salpêtrière, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Holloway, Robert" sort="Holloway, Robert" uniqKey="Holloway R" first="Robert" last="Holloway">Robert Holloway</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurology, University of Rochester, Rochester, New York</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Neurology, University of Rochester, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurology, Baylor College of Medicine, Houston, Texas</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Department of Neurology, Baylor College of Medicine, Houston</wicri:cityArea></affiliation></author><author><name sortKey="Kulisevsky, Jaime" sort="Kulisevsky, Jaime" uniqKey="Kulisevsky J" first="Jaime" last="Kulisevsky">Jaime Kulisevsky</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology and CIBERNED, Sant Pau Hospital, Barcelona, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neurology and CIBERNED, Sant Pau Hospital, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E." last="Lang">Anthony E. Lang</name><affiliation wicri:level="1"><mods:affiliation>Division of Neurology, University of Toronto, Toronto, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Neurology, University of Toronto, Toronto</wicri:regionArea></affiliation></author><author><name sortKey="Lees, Andrew" sort="Lees, Andrew" uniqKey="Lees A" first="Andrew" last="Lees">Andrew Lees</name><affiliation wicri:level="2"><mods:affiliation>Reta Lila Weston Institute of Neurological Studies, University College, London, England</mods:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Reta Lila Weston Institute of Neurological Studies, University College, London</wicri:cityArea></affiliation></author><author><name sortKey="Leurgans, Sue" sort="Leurgans, Sue" uniqKey="Leurgans S" first="Sue" last="Leurgans">Sue Leurgans</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Illinois</region></placeName><wicri:cityArea>Department of Neurological Sciences, Rush University Medical Center, Chicago</wicri:cityArea></affiliation></author><author><name sortKey="Lewitt, Peter A" sort="Lewitt, Peter A" uniqKey="Lewitt P" first="Peter A." last="Lewitt">Peter A. Lewitt</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurology, Wayne State University, Detroit, Michigan</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Michigan</region></placeName><wicri:cityArea>Department of Neurology, Wayne State University, Detroit</wicri:cityArea></affiliation></author><author><name sortKey="Nyenhuis, David" sort="Nyenhuis, David" uniqKey="Nyenhuis D" first="David" last="Nyenhuis">David Nyenhuis</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurology and Rehabilitation, University of Illinois, Chicago, Illinois</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Illinois</region></placeName><wicri:cityArea>Department of Neurology and Rehabilitation, University of Illinois, Chicago</wicri:cityArea></affiliation></author><author><name sortKey="Olanow, C Warren" sort="Olanow, C Warren" uniqKey="Olanow C" first="C. Warren" last="Olanow">C. Warren Olanow</name><affiliation wicri:level="2"><mods:affiliation>Department of Neurology, Mount Sinai School of Medicine, New York, New York</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Neurology, Mount Sinai School of Medicine, New York</wicri:cityArea></affiliation><affiliation wicri:level="2"><mods:affiliation>Department of Neuroscience, Mount Sinai School of Medicine, New York, New York</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Neuroscience, Mount Sinai School of Medicine, New York</wicri:cityArea></affiliation></author><author><name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name><affiliation wicri:level="1"><mods:affiliation>Laboratoire de Pharmacologie Médicale et Clinique, Toulouse University, Toulouse, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Pharmacologie Médicale et Clinique, Toulouse University, Toulouse</wicri:regionArea></affiliation></author><author><name sortKey="Schrag, Anette" sort="Schrag, Anette" uniqKey="Schrag A" first="Anette" last="Schrag">Anette Schrag</name><affiliation wicri:level="2"><mods:affiliation>Department of Clinical Neurosciences, University College, London, England</mods:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Department of Clinical Neurosciences, University College, London</wicri:cityArea></affiliation></author><author><name sortKey="Teresi, Jeanne A" sort="Teresi, Jeanne A" uniqKey="Teresi J" first="Jeanne A." last="Teresi">Jeanne A. Teresi</name><affiliation wicri:level="2"><mods:affiliation>Stroud Center, Division of General Medicine and Psychiatric Institute, Columbia University, New York, New York</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Stroud Center, Division of General Medicine and Psychiatric Institute, Columbia University, New York</wicri:cityArea></affiliation></author><author><name sortKey="Van Hilten, Jacobus J" sort="Van Hilten, Jacobus J" uniqKey="Van Hilten J" first="Jacobus J." last="Van Hilten">Jacobus J. Van Hilten</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Leiden University, Leiden, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, Leiden University, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Lapelle, Nancy" sort="Lapelle, Nancy" uniqKey="Lapelle N" first="Nancy" last="Lapelle">Nancy Lapelle</name><affiliation wicri:level="2"><mods:affiliation>Division of Preventive and Behavioral Medicine, University of Massachusetts, Worcester, Massachusetts</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Preventive and Behavioral Medicine, University of Massachusetts, Worcester</wicri:cityArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2008-11-15">2008-11-15</date><biblScope unit="vol">23</biblScope><biblScope unit="issue">15</biblScope><biblScope unit="page" from="2129">2129</biblScope><biblScope unit="page" to="2170">2170</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">20C8EC0AC3C3656D4CE380BDD9850EAC4AD525BA</idno><idno type="DOI">10.1002/mds.22340</idno><idno type="ArticleID">MDS22340</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term><term>UPDRS</term><term>clinimetrics</term><term>rating scales</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We present a clinimetric assessment of the Movement Disorder Society (MDS)‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS). The MDS‐UDPRS Task Force revised and expanded the UPDRS using recommendations from a published critique. The MDS‐UPDRS has four parts, namely, I: Non‐motor Experiences of Daily Living; II: Motor Experiences of Daily Living; III: Motor Examination; IV: Motor Complications. Twenty questions are completed by the patient/caregiver. Item‐specific instructions and an appendix of complementary additional scales are provided. Movement disorder specialists and study coordinators administered the UPDRS (55 items) and MDS‐UPDRS (65 items) to 877 English speaking (78% non‐Latino Caucasian) patients with Parkinson's disease from 39 sites. We compared the two scales using correlative techniques and factor analysis. The MDS‐UPDRS showed high internal consistency (Cronbach's alpha = 0.79–0.93 across parts) and correlated with the original UPDRS (ρ = 0.96). MDS‐UPDRS across‐part correlations ranged from 0.22 to 0.66. Reliable factor structures for each part were obtained (comparative fit index > 0.90 for each part), which support the use of sum scores for each part in preference to a total score of all parts. The combined clinimetric results of this study support the validity of the MDS‐UPDRS for rating PD. © 2008 Movement Disorder Society</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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