Postoperative gait deterioration after bilateral subthalamic nucleus stimulation in Parkinson's disease
Identifieur interne : 000449 ( Istex/Curation ); précédent : 000448; suivant : 000450Postoperative gait deterioration after bilateral subthalamic nucleus stimulation in Parkinson's disease
Auteurs : Bart F. L. Van Nuenen [Pays-Bas] ; Rianne A. J. Esselink [Pays-Bas] ; Marten Munneke [Pays-Bas] ; Johhannes D. Speelman [Pays-Bas] ; Teus Van Laar [Pays-Bas] ; Bastiaan R. Bloem [Pays-Bas]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-12-15.
English descriptors
- KwdEn :
Abstract
Deep brain stimulation of the subthalamic nuclei (STN) is a good therapeutic option to reduce dyskinesias and improve appendicular motor signs in well‐selected patients with advanced Parkinson's disease (PD). Concerns about long‐term adverse effects play an increasingly role in the decision whether or not to refer patients for this treatment. Worsening of gait as a consequence of STN stimulation for PD has been described, but may be under‐recognized in clinical practice. The aim of this study was to evaluate the effects of STN stimulation on gait relative to global outcome in a group of consecutively operated patients. For this purpose, we used a standardized patient questionnaire that asked about global outcome and specific effects on gait, as experienced both 6 months postoperatively and currently (at the time of completing the questionnaire; mean: 2.7 +/− 1.1 years). A delayed worsening of gait after bilateral STN stimulation was experienced by a considerable proportion of patients (42% of subjects, for gait in the OFF phase), and this was apparently relatively “selective” because their global outcome scores continued to be improved. These findings highlight the presence of a hitherto poorly recognized long‐term complication of bilateral STN stimulation. Further systematic studies are required to pinpoint the clinical and surgical determinants of this late gait deterioration. © 2008 Movement Disorder Society
Url:
DOI: 10.1002/mds.21986
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000449
Links to Exploration step
ISTEX:E2BC0681BF7190590EED612E285F6E8EE7832716Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Postoperative gait deterioration after bilateral subthalamic nucleus stimulation in Parkinson's disease</title>
<author><name sortKey="Van Nuenen, Bart F L" sort="Van Nuenen, Bart F L" uniqKey="Van Nuenen B" first="Bart F. L." last="Van Nuenen">Bart F. L. Van Nuenen</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Esselink, Rianne A J" sort="Esselink, Rianne A J" uniqKey="Esselink R" first="Rianne A. J." last="Esselink">Rianne A. J. Esselink</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><mods:affiliation>Department of Geriatrics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Geriatrics, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Munneke, Marten" sort="Munneke, Marten" uniqKey="Munneke M" first="Marten" last="Munneke">Marten Munneke</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Speelman, Johhannes D" sort="Speelman, Johhannes D" uniqKey="Speelman J" first="Johhannes D." last="Speelman">Johhannes D. Speelman</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Academic Medical Center, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Laar, Teus" sort="Van Laar, Teus" uniqKey="Van Laar T" first="Teus" last="Van Laar">Teus Van Laar</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University Medical Center,Groningen, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, University Medical Center,Groningen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bloem, Bastiaan R" sort="Bloem, Bastiaan R" uniqKey="Bloem B" first="Bastiaan R." last="Bloem">Bastiaan R. Bloem</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:E2BC0681BF7190590EED612E285F6E8EE7832716</idno>
<date when="2008" year="2008">2008</date>
<idno type="doi">10.1002/mds.21986</idno>
<idno type="url">https://api.istex.fr/document/E2BC0681BF7190590EED612E285F6E8EE7832716/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000449</idno>
<idno type="wicri:Area/Istex/Curation">000449</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Postoperative gait deterioration after bilateral subthalamic nucleus stimulation in Parkinson's disease</title>
<author><name sortKey="Van Nuenen, Bart F L" sort="Van Nuenen, Bart F L" uniqKey="Van Nuenen B" first="Bart F. L." last="Van Nuenen">Bart F. L. Van Nuenen</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Esselink, Rianne A J" sort="Esselink, Rianne A J" uniqKey="Esselink R" first="Rianne A. J." last="Esselink">Rianne A. J. Esselink</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><mods:affiliation>Department of Geriatrics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Geriatrics, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Munneke, Marten" sort="Munneke, Marten" uniqKey="Munneke M" first="Marten" last="Munneke">Marten Munneke</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Speelman, Johhannes D" sort="Speelman, Johhannes D" uniqKey="Speelman J" first="Johhannes D." last="Speelman">Johhannes D. Speelman</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Academic Medical Center, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Laar, Teus" sort="Van Laar, Teus" uniqKey="Van Laar T" first="Teus" last="Van Laar">Teus Van Laar</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, University Medical Center,Groningen, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, University Medical Center,Groningen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bloem, Bastiaan R" sort="Bloem, Bastiaan R" uniqKey="Bloem B" first="Bastiaan R." last="Bloem">Bastiaan R. Bloem</name>
<affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2008-12-15">2008-12-15</date>
<biblScope unit="vol">23</biblScope>
<biblScope unit="issue">16</biblScope>
<biblScope unit="page" from="2404">2404</biblScope>
<biblScope unit="page" to="2406">2406</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">E2BC0681BF7190590EED612E285F6E8EE7832716</idno>
<idno type="DOI">10.1002/mds.21986</idno>
<idno type="ArticleID">MDS21986</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term>
<term>deep brain stimulation</term>
<term>gait</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Deep brain stimulation of the subthalamic nuclei (STN) is a good therapeutic option to reduce dyskinesias and improve appendicular motor signs in well‐selected patients with advanced Parkinson's disease (PD). Concerns about long‐term adverse effects play an increasingly role in the decision whether or not to refer patients for this treatment. Worsening of gait as a consequence of STN stimulation for PD has been described, but may be under‐recognized in clinical practice. The aim of this study was to evaluate the effects of STN stimulation on gait relative to global outcome in a group of consecutively operated patients. For this purpose, we used a standardized patient questionnaire that asked about global outcome and specific effects on gait, as experienced both 6 months postoperatively and currently (at the time of completing the questionnaire; mean: 2.7 +/− 1.1 years). A delayed worsening of gait after bilateral STN stimulation was experienced by a considerable proportion of patients (42% of subjects, for gait in the OFF phase), and this was apparently relatively “selective” because their global outcome scores continued to be improved. These findings highlight the presence of a hitherto poorly recognized long‐term complication of bilateral STN stimulation. Further systematic studies are required to pinpoint the clinical and surgical determinants of this late gait deterioration. © 2008 Movement Disorder Society</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000449 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 000449 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Istex |étape= Curation |type= RBID |clé= ISTEX:E2BC0681BF7190590EED612E285F6E8EE7832716 |texte= Postoperative gait deterioration after bilateral subthalamic nucleus stimulation in Parkinson's disease }}
![]() | This area was generated with Dilib version V0.6.23. | ![]() |