Objective detection of subtle freezing of gait episodes in Parkinson's disease
Identifieur interne : 000174 ( Istex/Curation ); précédent : 000173; suivant : 000175Objective detection of subtle freezing of gait episodes in Parkinson's disease
Auteurs : Arnaud Delval [France, Pays-Bas] ; Anke H. Snijders [Pays-Bas] ; Vivian Weerdesteyn [Pays-Bas] ; Jacques E. Duysens [Pays-Bas] ; Luc Defebvre [France] ; Nir Giladi [Israël] ; Bastiaan R. Bloem [Pays-Bas]Source :
- Movement Disorders [ 0885-3185 ] ; 2010-08-15.
English descriptors
- KwdEn :
Abstract
Freezing of gait (FOG) is a clinically defined phenomenon of Parkinson's disease (PD). Recent evidence suggests that subtle FOG episodes can be elicited in a gait laboratory using suddenly appearing obstacles during treadmill walking. We evaluated which quantitative gait parameters identify such subtle FOG episodes. We included 10 PD patients with FOG, 10 PD patients without FOG, and 10 controls. Subjects walked on a motorized treadmill while avoiding unexpectedly appearing obstacles. Treadmill walking was videotaped, and FOG episodes were identified by two independent experts. Gait was also analyzed using detailed kinematics. Knee joint signals were processed using time–frequency analysis with combinations of sliding fast Fourier transform and wavelets transform. Twenty FOG episodes occurred during treadmill walking in 5 patients (all with clinically certified FOG), predominantly in relation to obstacle avoidance. FOG was brief when it occurred just before or after obstacle crossing and was characterized by short, rapid steps. Frequency analysis showed a typical qualitative pattern: before the FOG episode an increase in dominant frequency in the 0 to 3 Hz band (festination), followed by decreased power in 0 to 3 Hz band and an increased power in the 3 to 8 Hz band during the FOG episode. This pattern led to an increased FOG index as a qualitative measure. These approaches detected even very brief FOG with acceptable sensitivity (75–83%) and specificity (>95%). We conclude that time–frequency analysis is an appropriate approach to detect brief and subtle FOG episodes. Future work will need to decide whether this approach can support or even replace expert clinical opinion. © 2010 Movement Disorder Society
Url:
DOI: 10.1002/mds.23159
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000174
Links to Exploration step
ISTEX:2FC6DAA12D9EA0F0A18480B6C09F29309059D962Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Objective detection of subtle freezing of gait episodes in Parkinson's disease</title><author><name sortKey="Delval, Arnaud" sort="Delval, Arnaud" uniqKey="Delval A" first="Arnaud" last="Delval">Arnaud Delval</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology and Movement Disorders, Regional University Hospital, Lille Cedex, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology and Movement Disorders, Regional University Hospital, Lille Cedex</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Clinical Neurophysiology, Regional University Hospital, Lille Cedex, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Clinical Neurophysiology, Regional University Hospital, Lille Cedex</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Donders Center for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, Donders Center for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Snijders, Anke H" sort="Snijders, Anke H" uniqKey="Snijders A" first="Anke H." last="Snijders">Anke H. Snijders</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Donders Center for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, Donders Center for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Weerdesteyn, Vivian" sort="Weerdesteyn, Vivian" uniqKey="Weerdesteyn V" first="Vivian" last="Weerdesteyn">Vivian Weerdesteyn</name><affiliation wicri:level="1"><mods:affiliation>Department of Rehabilitation, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Rehabilitation, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Duysens, Jacques E" sort="Duysens, Jacques E" uniqKey="Duysens J" first="Jacques E." last="Duysens">Jacques E. Duysens</name><affiliation wicri:level="1"><mods:affiliation>Department of Rehabilitation, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Rehabilitation, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Defebvre, Luc" sort="Defebvre, Luc" uniqKey="Defebvre L" first="Luc" last="Defebvre">Luc Defebvre</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology and Movement Disorders, Regional University Hospital, Lille Cedex, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology and Movement Disorders, Regional University Hospital, Lille Cedex</wicri:regionArea></affiliation></author><author><name sortKey="Giladi, Nir" sort="Giladi, Nir" uniqKey="Giladi N" first="Nir" last="Giladi">Nir Giladi</name><affiliation wicri:level="1"><mods:affiliation>Movement Disorders Unit, Department of Neurology, Tel‐Aviv Sourasky Medical Center, Sackler School of Medicine, Tel‐Aviv University, Tel‐Aviv, Israel</mods:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Movement Disorders Unit, Department of Neurology, Tel‐Aviv Sourasky Medical Center, Sackler School of Medicine, Tel‐Aviv University, Tel‐Aviv</wicri:regionArea></affiliation></author><author><name sortKey="Bloem, Bastiaan R" sort="Bloem, Bastiaan R" uniqKey="Bloem B" first="Bastiaan R." last="Bloem">Bastiaan R. Bloem</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Donders Center for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, Donders Center for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:2FC6DAA12D9EA0F0A18480B6C09F29309059D962</idno><date when="2010" year="2010">2010</date><idno type="doi">10.1002/mds.23159</idno><idno type="url">https://api.istex.fr/document/2FC6DAA12D9EA0F0A18480B6C09F29309059D962/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000174</idno><idno type="wicri:Area/Istex/Curation">000174</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Objective detection of subtle freezing of gait episodes in Parkinson's disease</title><author><name sortKey="Delval, Arnaud" sort="Delval, Arnaud" uniqKey="Delval A" first="Arnaud" last="Delval">Arnaud Delval</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology and Movement Disorders, Regional University Hospital, Lille Cedex, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology and Movement Disorders, Regional University Hospital, Lille Cedex</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Clinical Neurophysiology, Regional University Hospital, Lille Cedex, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Clinical Neurophysiology, Regional University Hospital, Lille Cedex</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Donders Center for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, Donders Center for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Snijders, Anke H" sort="Snijders, Anke H" uniqKey="Snijders A" first="Anke H." last="Snijders">Anke H. Snijders</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Donders Center for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, Donders Center for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Weerdesteyn, Vivian" sort="Weerdesteyn, Vivian" uniqKey="Weerdesteyn V" first="Vivian" last="Weerdesteyn">Vivian Weerdesteyn</name><affiliation wicri:level="1"><mods:affiliation>Department of Rehabilitation, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Rehabilitation, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Duysens, Jacques E" sort="Duysens, Jacques E" uniqKey="Duysens J" first="Jacques E." last="Duysens">Jacques E. Duysens</name><affiliation wicri:level="1"><mods:affiliation>Department of Rehabilitation, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Rehabilitation, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Defebvre, Luc" sort="Defebvre, Luc" uniqKey="Defebvre L" first="Luc" last="Defebvre">Luc Defebvre</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology and Movement Disorders, Regional University Hospital, Lille Cedex, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology and Movement Disorders, Regional University Hospital, Lille Cedex</wicri:regionArea></affiliation></author><author><name sortKey="Giladi, Nir" sort="Giladi, Nir" uniqKey="Giladi N" first="Nir" last="Giladi">Nir Giladi</name><affiliation wicri:level="1"><mods:affiliation>Movement Disorders Unit, Department of Neurology, Tel‐Aviv Sourasky Medical Center, Sackler School of Medicine, Tel‐Aviv University, Tel‐Aviv, Israel</mods:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Movement Disorders Unit, Department of Neurology, Tel‐Aviv Sourasky Medical Center, Sackler School of Medicine, Tel‐Aviv University, Tel‐Aviv</wicri:regionArea></affiliation></author><author><name sortKey="Bloem, Bastiaan R" sort="Bloem, Bastiaan R" uniqKey="Bloem B" first="Bastiaan R." last="Bloem">Bastiaan R. Bloem</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Donders Center for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, Donders Center for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2010-08-15">2010-08-15</date><biblScope unit="vol">25</biblScope><biblScope unit="issue">11</biblScope><biblScope unit="page" from="1684">1684</biblScope><biblScope unit="page" to="1693">1693</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">2FC6DAA12D9EA0F0A18480B6C09F29309059D962</idno><idno type="DOI">10.1002/mds.23159</idno><idno type="ArticleID">MDS23159</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term><term>fast Fourier transform</term><term>festination</term><term>freezing of gait</term><term>frequency analysis</term><term>wavelets</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Freezing of gait (FOG) is a clinically defined phenomenon of Parkinson's disease (PD). Recent evidence suggests that subtle FOG episodes can be elicited in a gait laboratory using suddenly appearing obstacles during treadmill walking. We evaluated which quantitative gait parameters identify such subtle FOG episodes. We included 10 PD patients with FOG, 10 PD patients without FOG, and 10 controls. Subjects walked on a motorized treadmill while avoiding unexpectedly appearing obstacles. Treadmill walking was videotaped, and FOG episodes were identified by two independent experts. Gait was also analyzed using detailed kinematics. Knee joint signals were processed using time–frequency analysis with combinations of sliding fast Fourier transform and wavelets transform. Twenty FOG episodes occurred during treadmill walking in 5 patients (all with clinically certified FOG), predominantly in relation to obstacle avoidance. FOG was brief when it occurred just before or after obstacle crossing and was characterized by short, rapid steps. Frequency analysis showed a typical qualitative pattern: before the FOG episode an increase in dominant frequency in the 0 to 3 Hz band (festination), followed by decreased power in 0 to 3 Hz band and an increased power in the 3 to 8 Hz band during the FOG episode. This pattern led to an increased FOG index as a qualitative measure. These approaches detected even very brief FOG with acceptable sensitivity (75–83%) and specificity (>95%). We conclude that time–frequency analysis is an appropriate approach to detect brief and subtle FOG episodes. Future work will need to decide whether this approach can support or even replace expert clinical opinion. © 2010 Movement Disorder Society</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000174 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 000174 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Istex
|étape= Curation
|type= RBID
|clé= ISTEX:2FC6DAA12D9EA0F0A18480B6C09F29309059D962
|texte= Objective detection of subtle freezing of gait episodes in Parkinson's disease
}}
| This area was generated with Dilib version V0.6.23. |  |