Movement Disorders (revue)

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Reversible posterior leukoencephalopathy syndrome in a patient with multiple system atrophy: A possible association with oral midodrine treatment

Identifieur interne : 003825 ( Istex/Corpus ); précédent : 003824; suivant : 003826

Reversible posterior leukoencephalopathy syndrome in a patient with multiple system atrophy: A possible association with oral midodrine treatment

Auteurs : Joong-Seok Kim ; Kwang-Soo Lee ; Sung-Chul Lim ; Jae-Young Ahn ; In-Uk Song ; Yeong-In Kim ; Bum-Soo Kim ; Hee-Tae Kim

Source :

RBID : ISTEX:3E05B4D045E3E11D652EDED5E31A85E6EF87F348

English descriptors

Abstract

We describe a 51‐year‐old man with a 3‐year history of multiple system atrophy, who developed a reversible posterior leukoencephalopathy syndrome (RPLS) after receiving prescription midodrine for therapeutic treatment of orthostatic hypotension. Typical reversible magnetic resonance imaging findings, following treatment with midodrine, suggested a possible relationship between midodrine treatment, supine hypertension, and RPLS, although a cause‐and‐effect relationship cannot be confirmed. © 2007 Movement Disorder Society

Url:
DOI: 10.1002/mds.21461

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ISTEX:3E05B4D045E3E11D652EDED5E31A85E6EF87F348

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<p>We describe a 51‐year‐old man with a 3‐year history of multiple system atrophy, who developed a reversible posterior leukoencephalopathy syndrome (RPLS) after receiving prescription midodrine for therapeutic treatment of orthostatic hypotension. Typical reversible magnetic resonance imaging findings, following treatment with midodrine, suggested a possible relationship between midodrine treatment, supine hypertension, and RPLS, although a cause‐and‐effect relationship cannot be confirmed. © 2007 Movement Disorder Society</p>
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<abstract lang="en">We describe a 51‐year‐old man with a 3‐year history of multiple system atrophy, who developed a reversible posterior leukoencephalopathy syndrome (RPLS) after receiving prescription midodrine for therapeutic treatment of orthostatic hypotension. Typical reversible magnetic resonance imaging findings, following treatment with midodrine, suggested a possible relationship between midodrine treatment, supine hypertension, and RPLS, although a cause‐and‐effect relationship cannot be confirmed. © 2007 Movement Disorder Society</abstract>
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