Movement Disorders (revue)

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Impact of pramipexole on the onset of levodopa‐related dyskinesias

Identifieur interne : 003742 ( Istex/Corpus ); précédent : 003741; suivant : 003743

Impact of pramipexole on the onset of levodopa‐related dyskinesias

Auteurs : Radu Constantinescu ; Megan Romer ; Michael P. Mcdermott ; Cornelia Kamp ; Karl Kieburtz

Source :

RBID : ISTEX:B0896B7AACAB7F89FDC7897DCC5BD214C3C4D1C5

English descriptors

Abstract

Dyskinesias are a major complication of dopaminergic therapy in the long‐term treatment of Parkinson's disease. In the CALM‐PD trial, subjects were initially randomized to levodopa or pramipexole and could later add levodopa if needed. After adjusting for disease duration and daily levodopa dosage, the incidence of dyskinesias after initiating levodopa was not significantly different among subjects initially randomized to levodopa and those initially randomized to pramipexole. © 2007 Movement Disorder Society

Url:
DOI: 10.1002/mds.21292

Links to Exploration step

ISTEX:B0896B7AACAB7F89FDC7897DCC5BD214C3C4D1C5

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<titleInfo type="alternative" contentType="CDATA" lang="en">
<title>Impact of pramipexole on the onset of levodopa‐related dyskinesias</title>
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<name type="personal">
<namePart type="given">Radu</namePart>
<namePart type="family">Constantinescu</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA</affiliation>
<description>Correspondence: Neurologkliniken, Sahlgrenska University Hospital, 413 45 Göteborg, Sweden</description>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Megan</namePart>
<namePart type="family">Romer</namePart>
<namePart type="termsOfAddress">MS</namePart>
<affiliation>Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Michael P.</namePart>
<namePart type="family">McDermott</namePart>
<namePart type="termsOfAddress">PhD</namePart>
<affiliation>Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA</affiliation>
<affiliation>Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, New York, USA</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Cornelia</namePart>
<namePart type="family">Kamp</namePart>
<namePart type="termsOfAddress">MBA</namePart>
<affiliation>Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Karl</namePart>
<namePart type="family">Kieburtz</namePart>
<namePart type="termsOfAddress">MD, MPH</namePart>
<affiliation>Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
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</name>
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<dateIssued encoding="w3cdtf">2007-07-15</dateIssued>
<dateCaptured encoding="w3cdtf">2006-04-21</dateCaptured>
<dateValid encoding="w3cdtf">2006-09-14</dateValid>
<copyrightDate encoding="w3cdtf">2007</copyrightDate>
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<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
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<abstract lang="en">Dyskinesias are a major complication of dopaminergic therapy in the long‐term treatment of Parkinson's disease. In the CALM‐PD trial, subjects were initially randomized to levodopa or pramipexole and could later add levodopa if needed. After adjusting for disease duration and daily levodopa dosage, the incidence of dyskinesias after initiating levodopa was not significantly different among subjects initially randomized to levodopa and those initially randomized to pramipexole. © 2007 Movement Disorder Society</abstract>
<note type="funding">Boehringer Ingelheim and the Parkinson Disease Foundation</note>
<subject lang="en">
<genre>Keywords</genre>
<topic>Parkinson's disease</topic>
<topic>dyskinesias</topic>
<topic>pramipexole</topic>
<topic>levodopa</topic>
<topic>dopamine agonists</topic>
</subject>
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<title>Movement Disorders</title>
<subTitle>Official Journal of the Movement Disorder Society</subTitle>
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<titleInfo type="abbreviated">
<title>Mov. Disord.</title>
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<subject>
<genre>article category</genre>
<topic>Brief Report</topic>
</subject>
<identifier type="ISSN">0885-3185</identifier>
<identifier type="eISSN">1531-8257</identifier>
<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
<identifier type="PublisherID">MDS</identifier>
<part>
<date>2007</date>
<detail type="volume">
<caption>vol.</caption>
<number>22</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>9</number>
</detail>
<extent unit="pages">
<start>1317</start>
<end>1319</end>
<total>3</total>
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</part>
</relatedItem>
<identifier type="istex">B0896B7AACAB7F89FDC7897DCC5BD214C3C4D1C5</identifier>
<identifier type="DOI">10.1002/mds.21292</identifier>
<identifier type="ArticleID">MDS21292</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2007 Movement Disorder Society</accessCondition>
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<recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin>
<recordContentSource>WILEY</recordContentSource>
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