Mood and anxiety fluctuation in Parkinson's disease associated with levodopa infusion: Preliminary findings
Identifieur interne : 003479 ( Istex/Corpus ); précédent : 003478; suivant : 003480Mood and anxiety fluctuation in Parkinson's disease associated with levodopa infusion: Preliminary findings
Auteurs : Maricle ; John G. Nutt ; Julie H. CarterSource :
- Movement Disorders [ 0885-3185 ] ; 1995-05.
English descriptors
Abstract
Pilot data on mood and anxiety changes in 15 Parkinson's disease patients with motor fluctuations are described based on ratings every 30 min for 5 h bracketing a 2‐h constant‐rate levodopa infusion. Robust mood and anxiety effects slightly preceded but temporally paralleled fluctuations in motor tapping scores. Research nurse ratings blind to patient ratings corroborated the changes. The magnitude of changes in mood and anxiety scores did not correlate with the magnitude of changes in tapping scores. The findings of this uncontrolled study suggest mood and anxiety fluctuations may be a common and potentially important component of levodopa‐induced fluctuation.
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DOI: 10.1002/mds.870100316
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ISTEX:A801EC9BE0AE3EEC18198DD6124FE87BCE25471ELe document en format XML
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Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="1995-05"></date><biblScope unit="vol">10</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="329">329</biblScope><biblScope unit="page" to="332">332</biblScope></imprint></monogr><idno type="istex">A801EC9BE0AE3EEC18198DD6124FE87BCE25471E</idno><idno type="DOI">10.1002/mds.870100316</idno><idno type="ArticleID">MDS870100316</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1995</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Pilot data on mood and anxiety changes in 15 Parkinson's disease patients with motor fluctuations are described based on ratings every 30 min for 5 h bracketing a 2‐h constant‐rate levodopa infusion. Robust mood and anxiety effects slightly preceded but temporally paralleled fluctuations in motor tapping scores. Research nurse ratings blind to patient ratings corroborated the changes. The magnitude of changes in mood and anxiety scores did not correlate with the magnitude of changes in tapping scores. The findings of this uncontrolled study suggest mood and anxiety fluctuations may be a common and potentially important component of levodopa‐induced fluctuation.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Parkinson's disease</term></item><item><term>Levodopa</term></item><item><term>Depressive disorder</term></item><item><term>Anxiety</term></item><item><term>Mood fluctuations</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1994-11-20">Registration</change><change when="1995-05">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/A801EC9BE0AE3EEC18198DD6124FE87BCE25471E/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="subtitle">Official Journal of the Movement Disorder Society</title><title type="short">Mov. 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Sam Jackson Park Road, Portland, OR 97201, U.S.A.</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:MDS.MDS870100316.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="3"></count><count type="tableTotal" number="0"></count><count type="referenceTotal" number="10"></count></countGroup><titleGroup><title type="main" xml:lang="en">Mood and anxiety fluctuation in Parkinson's disease associated with levodopa infusion: Preliminary findings</title><title type="short" xml:lang="en">LEVODOPA AND MOOD</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><honorifics>Dr.</honorifics><givenNames>Robert A.</givenNames><familyName>Maricle</familyName></personName></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af2 #af3"><personName><givenNames>John G.</givenNames><familyName>Nutt</familyName></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Julie H.</givenNames><familyName>Carter</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="US" type="organization"><unparsedAffiliation>Department of Psychiatry, Oregon Health Sciences University, Portland, Oregon, U.S.A.</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="US" type="organization"><unparsedAffiliation>Department of Neurology, Oregon Health Sciences University, Portland, Oregon, U.S.A.</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="US" type="organization"><unparsedAffiliation>Department of Pharmacology, Oregon Health Sciences University, Portland, Oregon, U.S.A.</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">Parkinson's disease</keyword><keyword xml:id="kwd2">Levodopa</keyword><keyword xml:id="kwd3">Depressive disorder</keyword><keyword xml:id="kwd4">Anxiety</keyword><keyword xml:id="kwd5">Mood fluctuations</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Pilot data on mood and anxiety changes in 15 Parkinson's disease patients with motor fluctuations are described based on ratings every 30 min for 5 h bracketing a 2‐h constant‐rate levodopa infusion. Robust mood and anxiety effects slightly preceded but temporally paralleled fluctuations in motor tapping scores. Research nurse ratings blind to patient ratings corroborated the changes. The magnitude of changes in mood and anxiety scores did not correlate with the magnitude of changes in tapping scores. The findings of this uncontrolled study suggest mood and anxiety fluctuations may be a common and potentially important component of levodopa‐induced fluctuation.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Mood and anxiety fluctuation in Parkinson's disease associated with levodopa infusion: Preliminary findings</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>LEVODOPA AND MOOD</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Mood and anxiety fluctuation in Parkinson's disease associated with levodopa infusion: Preliminary findings</title></titleInfo><name type="personal"><namePart type="termsOfAddress">Dr.</namePart><namePart type="family">Maricle</namePart><affiliation>Department of Psychiatry, Oregon Health Sciences University, Portland, Oregon, U.S.A.</affiliation><description>Correspondence: Department of Psychiatry—OP‐02, Oregon Health Sciences University, 3181 S.W. 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Robust mood and anxiety effects slightly preceded but temporally paralleled fluctuations in motor tapping scores. Research nurse ratings blind to patient ratings corroborated the changes. The magnitude of changes in mood and anxiety scores did not correlate with the magnitude of changes in tapping scores. The findings of this uncontrolled study suggest mood and anxiety fluctuations may be a common and potentially important component of levodopa‐induced fluctuation.</abstract><subject lang="en"><genre>Keywords</genre><topic>Parkinson's disease</topic><topic>Levodopa</topic><topic>Depressive disorder</topic><topic>Anxiety</topic><topic>Mood fluctuations</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. 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