Parkinson's disease, subthalamic stimulation, and selection of candidates: A pathological study
Identifieur interne : 003348 ( Istex/Corpus ); précédent : 003347; suivant : 003349Parkinson's disease, subthalamic stimulation, and selection of candidates: A pathological study
Auteurs : Bechir Jarraya ; Anne-Marie Bonnet ; Charles Duyckaerts ; Jean-Luc Houeto ; Philippe Cornu ; Jean-Jacques Hauw ; Yves AgidSource :
- Movement Disorders [ 0885-3185 ] ; 2003-12.
English descriptors
Abstract
We report on a patient with Parkinson's disease (PD) who was moderately improved by stimulation of the subthalamic nucleus (STN) and died 2 years after electrode implantation. After neurosurgery, symptoms that had responded to levodopa treatment preoperatively continued to improve. Postural instability, dysarthria, and cognitive impairment continued to worsen, despite STN stimulation and levodopa treatment. Postmortem examination of the brain confirmed the diagnosis of PD and showed that the electrodes had been correctly positioned within the STN. The failure of STN stimulation in this patient confirms the importance of screening and excluding patients from surgery with evolving parkinsonian axial symptoms or cognitive impairment. © 2003 Movement Disorder Society
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DOI: 10.1002/mds.10607
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ISTEX:9C7A8C4B14DAAE696BC221EB779B4ACCF6AD3E7BLe document en format XML
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France</mods:affiliation></affiliation></author><author><name sortKey="Hauw, Jean Acques" sort="Hauw, Jean Acques" uniqKey="Hauw J" first="Jean-Jacques" last="Hauw">Jean-Jacques Hauw</name><affiliation><mods:affiliation>Laboratoire de Neuropathologie Escourolle and INSERM U106 and U360, Hôpital de la Salpêtrière, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Agid, Yves" sort="Agid, Yves" uniqKey="Agid Y" first="Yves" last="Agid">Yves Agid</name><affiliation><mods:affiliation>Fédération de Neurologie, Centre d'Investigation Clinique and Institut National de la Santé et de la Recherche Médicale (INSERM) U289, Hôpital de la Salpêtrière, Paris, France</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. 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After neurosurgery, symptoms that had responded to levodopa treatment preoperatively continued to improve. Postural instability, dysarthria, and cognitive impairment continued to worsen, despite STN stimulation and levodopa treatment. Postmortem examination of the brain confirmed the diagnosis of PD and showed that the electrodes had been correctly positioned within the STN. The failure of STN stimulation in this patient confirms the importance of screening and excluding patients from surgery with evolving parkinsonian axial symptoms or cognitive impairment. © 2003 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Bechir Jarraya MD</name><affiliations><json:string>Fédération de Neurologie, Centre d'Investigation Clinique and Institut National de la Santé et de la Recherche Médicale (INSERM) U289, Hôpital de la Salpêtrière, Paris, France</json:string></affiliations></json:item><json:item><name>Anne‐Marie Bonnet MD</name><affiliations><json:string>Fédération de Neurologie, Centre d'Investigation Clinique and Institut National de la Santé et de la Recherche Médicale (INSERM) U289, Hôpital de la Salpêtrière, Paris, France</json:string></affiliations></json:item><json:item><name>Charles Duyckaerts MD</name><affiliations><json:string>Laboratoire de Neuropathologie Escourolle and INSERM U106 and U360, Hôpital de la Salpêtrière, Paris, France</json:string></affiliations></json:item><json:item><name>Jean‐Luc Houeto MD</name><affiliations><json:string>Fédération de Neurologie, Centre d'Investigation Clinique and Institut National de la Santé et de la Recherche Médicale (INSERM) U289, Hôpital de la Salpêtrière, Paris, France</json:string></affiliations></json:item><json:item><name>Philippe Cornu MD</name><affiliations><json:string>Service de Neurochirurgie, Hôpital de la Salpêtrière, Paris, France</json:string></affiliations></json:item><json:item><name>Jean‐Jacques Hauw MD</name><affiliations><json:string>Laboratoire de Neuropathologie Escourolle and INSERM U106 and U360, Hôpital de la Salpêtrière, Paris, France</json:string></affiliations></json:item><json:item><name>Yves Agid MD, PhD</name><affiliations><json:string>Fédération de Neurologie, Centre d'Investigation Clinique and Institut National de la Santé et de la Recherche Médicale (INSERM) U289, Hôpital de la Salpêtrière, Paris, France</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>subthalamic stimulation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>axial symptoms</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>neuropathology</value></json:item></subject><language><json:string>eng</json:string></language><abstract>We report on a patient with Parkinson's disease (PD) who was moderately improved by stimulation of the subthalamic nucleus (STN) and died 2 years after electrode implantation. After neurosurgery, symptoms that had responded to levodopa treatment preoperatively continued to improve. Postural instability, dysarthria, and cognitive impairment continued to worsen, despite STN stimulation and levodopa treatment. Postmortem examination of the brain confirmed the diagnosis of PD and showed that the electrodes had been correctly positioned within the STN. 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stimulation</keyword><keyword xml:id="kwd3">axial symptoms</keyword><keyword xml:id="kwd4">neuropathology</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>We report on a patient with Parkinson's disease (PD) who was moderately improved by stimulation of the subthalamic nucleus (STN) and died 2 years after electrode implantation. After neurosurgery, symptoms that had responded to levodopa treatment preoperatively continued to improve. Postural instability, dysarthria, and cognitive impairment continued to worsen, despite STN stimulation and levodopa treatment. Postmortem examination of the brain confirmed the diagnosis of PD and showed that the electrodes had been correctly positioned within the STN. The failure of STN stimulation in this patient confirms the importance of screening and excluding patients from surgery with evolving parkinsonian axial symptoms or cognitive impairment. © 2003 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Parkinson's disease, subthalamic stimulation, and selection of candidates: A pathological study</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Failure of Subthalamic Stimulation</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Parkinson's disease, subthalamic stimulation, and selection of candidates: A pathological study</title></titleInfo><name type="personal"><namePart type="given">Bechir</namePart><namePart type="family">Jarraya</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Fédération de Neurologie, Centre d'Investigation Clinique and Institut National de la Santé et de la Recherche Médicale (INSERM) U289, Hôpital de la Salpêtrière, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Anne‐Marie</namePart><namePart type="family">Bonnet</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Fédération de Neurologie, Centre d'Investigation Clinique and Institut National de la Santé et de la Recherche Médicale (INSERM) U289, Hôpital de la Salpêtrière, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Charles</namePart><namePart type="family">Duyckaerts</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Laboratoire de Neuropathologie Escourolle and INSERM U106 and U360, Hôpital de la Salpêtrière, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jean‐Luc</namePart><namePart type="family">Houeto</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Fédération de Neurologie, Centre d'Investigation Clinique and Institut National de la Santé et de la Recherche Médicale (INSERM) U289, Hôpital de la Salpêtrière, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Philippe</namePart><namePart type="family">Cornu</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Service de Neurochirurgie, Hôpital de la Salpêtrière, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jean‐Jacques</namePart><namePart type="family">Hauw</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Laboratoire de Neuropathologie Escourolle and INSERM U106 and U360, Hôpital de la Salpêtrière, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yves</namePart><namePart type="family">Agid</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Fédération de Neurologie, Centre d'Investigation Clinique and Institut National de la Santé et de la Recherche Médicale (INSERM) U289, Hôpital de la Salpêtrière, Paris, France</affiliation><description>Correspondence: Centre d'Investigation Clinique, Hôpital de la Salpêtrière, 47 boulevard de l'Hôpital, 75013 Paris, France</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2003-12</dateIssued><dateCaptured encoding="w3cdtf">2002-12-31</dateCaptured><dateValid encoding="w3cdtf">2003-06-13</dateValid><copyrightDate encoding="w3cdtf">2003</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="tables">1</extent><extent unit="references">12</extent><extent unit="words">2107</extent></physicalDescription><abstract lang="en">We report on a patient with Parkinson's disease (PD) who was moderately improved by stimulation of the subthalamic nucleus (STN) and died 2 years after electrode implantation. After neurosurgery, symptoms that had responded to levodopa treatment preoperatively continued to improve. Postural instability, dysarthria, and cognitive impairment continued to worsen, despite STN stimulation and levodopa treatment. Postmortem examination of the brain confirmed the diagnosis of PD and showed that the electrodes had been correctly positioned within the STN. The failure of STN stimulation in this patient confirms the importance of screening and excluding patients from surgery with evolving parkinsonian axial symptoms or cognitive impairment. © 2003 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>Parkinson's disease</topic><topic>subthalamic stimulation</topic><topic>axial symptoms</topic><topic>neuropathology</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><detail type="issue"><caption>no.</caption><number>12</number></detail><extent unit="pages"><start>1517</start><end>1520</end><total>4</total></extent></part></relatedItem><identifier type="istex">9C7A8C4B14DAAE696BC221EB779B4ACCF6AD3E7B</identifier><identifier type="DOI">10.1002/mds.10607</identifier><identifier type="ArticleID">MDS10607</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2003 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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