Decreased striatal dopamine transporter binding in a patient with extrapontine myelinolysis
Identifieur interne : 003323 ( Istex/Corpus ); précédent : 003322; suivant : 003324Decreased striatal dopamine transporter binding in a patient with extrapontine myelinolysis
Auteurs : Joong-Seok Kim ; Kwang-Soo Lee ; Si-Ryung Han ; Yong-An ChungSource :
- Movement Disorders [ 0885-3185 ] ; 2003-03.
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- KwdEn :
Abstract
We describe the case of a 61‐year‐old woman who developed extrapontine myelinolysis (EPM) with parkinsonism. Decreased striatal dopamine transporter binding assessed by [123I]N‐(3‐iodopropen‐2‐yl)‐2β‐carbomethoxy‐3β‐(4‐chlorophenyl) tropane and single photon emission computed tomography ([123I]IPT) SPECT) were observed in the patient, suggesting that osmotic injury causes the demyelination of nigrostriatal dopaminergic neurons and that such injury may be involved in the pathogenesis of EPM with parkinsonism.
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DOI: 10.1002/mds.10331
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