Bilateral subthalamic nucleus stimulation in a parkinsonian patient with preoperative deficits in speech and cognition: Persistent improvement in mobility but increased dependency: A case study
Identifieur interne : 003273 ( Istex/Corpus ); précédent : 003272; suivant : 003274Bilateral subthalamic nucleus stimulation in a parkinsonian patient with preoperative deficits in speech and cognition: Persistent improvement in mobility but increased dependency: A case study
Auteurs : Marwan I. Hariz ; Folke Johansson ; Parvis Shamsgovara ; Eva Johansson ; Gun-Marie Hariz ; Markku FagerlundSource :
- Movement Disorders [ 0885-3185 ] ; 2000-01.
English descriptors
Abstract
We report a patient with advanced Parkinson's disease, including severe and frequent off periods with freezing of gait, moderate dysphonia, and some cognitive impairment, who underwent bilateral subthalamic nucleus (STN) stimulation. The patient was followed for 1 year after surgery, showing persistent good mobility without off periods and without freezing, which reverted completely when stopping the stimulation. There was deterioration of cognition as well as increased aphonia and drooling, all of which remained when the stimulation was turned off. The striking improvement in motor symptoms following STN stimulation was not paralleled by improvement in disability, probably as a result of a cognitive decline, suggesting a diagnosis of Parkinson's disease with dementia. We conclude that chronic STN stimulation is efficient in alleviating akinetic motor symptoms including gait freezing; this surgery should be offered before patients start to exhibit speech or cognitive disturbances.
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DOI: 10.1002/1531-8257(200001)15:1<136::AID-MDS1021>3.0.CO;2-5
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Hariz</name><affiliation><mods:affiliation>Department of Neurosurgery, University Hospital, Umeéa, Sweden</mods:affiliation></affiliation></author><author><name sortKey="Johansson, Folke" sort="Johansson, Folke" uniqKey="Johansson F" first="Folke" last="Johansson">Folke Johansson</name><affiliation><mods:affiliation>Department of Neurology, University Hospital, Umeéa, Sweden</mods:affiliation></affiliation></author><author><name sortKey="Shamsgovara, Parvis" sort="Shamsgovara, Parvis" uniqKey="Shamsgovara P" first="Parvis" last="Shamsgovara">Parvis Shamsgovara</name><affiliation><mods:affiliation>Department of Neurosurgery, University Hospital, Umeéa, Sweden</mods:affiliation></affiliation></author><author><name sortKey="Johansson, Eva" sort="Johansson, Eva" uniqKey="Johansson E" first="Eva" last="Johansson">Eva Johansson</name><affiliation><mods:affiliation>Department of Neurology, University Hospital, Umeéa, Sweden</mods:affiliation></affiliation></author><author><name sortKey="Hariz, Gun Arie" sort="Hariz, Gun Arie" uniqKey="Hariz G" first="Gun-Marie" last="Hariz">Gun-Marie Hariz</name><affiliation><mods:affiliation>Department of Rehabilitation Medicine, University Hospital, Umeéa, Sweden</mods:affiliation></affiliation></author><author><name sortKey="Fagerlund, Markku" sort="Fagerlund, Markku" uniqKey="Fagerlund M" first="Markku" last="Fagerlund">Markku Fagerlund</name><affiliation><mods:affiliation>Department of Neuroradiology, University Hospital, Umeéa, Sweden</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:DCCCED9930270C4BE7443CE7F93CA3FE81FCDCE8</idno><date when="2000" year="2000">2000</date><idno type="doi">10.1002/1531-8257(200001)15:1<136::AID-MDS1021>3.0.CO;2-5</idno><idno type="url">https://api.istex.fr/document/DCCCED9930270C4BE7443CE7F93CA3FE81FCDCE8/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">003273</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Bilateral subthalamic nucleus stimulation in a parkinsonian patient with preoperative deficits in speech and cognition: Persistent improvement in mobility but increased dependency: A case study</title><author><name sortKey="Hariz, Marwan I" sort="Hariz, Marwan I" uniqKey="Hariz M" first="Marwan I." last="Hariz">Marwan I. 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The patient was followed for 1 year after surgery, showing persistent good mobility without off periods and without freezing, which reverted completely when stopping the stimulation. There was deterioration of cognition as well as increased aphonia and drooling, all of which remained when the stimulation was turned off. The striking improvement in motor symptoms following STN stimulation was not paralleled by improvement in disability, probably as a result of a cognitive decline, suggesting a diagnosis of Parkinson's disease with dementia. We conclude that chronic STN stimulation is efficient in alleviating akinetic motor symptoms including gait freezing; this surgery should be offered before patients start to exhibit speech or cognitive disturbances.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Marwan I. Hariz MD, PhD</name><affiliations><json:string>Department of Neurosurgery, University Hospital, Umeéa, Sweden</json:string></affiliations></json:item><json:item><name>Folke Johansson MD, PhD</name><affiliations><json:string>Department of Neurology, University Hospital, Umeéa, Sweden</json:string></affiliations></json:item><json:item><name>Parvis Shamsgovara MD</name><affiliations><json:string>Department of Neurosurgery, University Hospital, Umeéa, Sweden</json:string></affiliations></json:item><json:item><name>Eva Johansson</name><affiliations><json:string>Department of Neurology, University Hospital, Umeéa, Sweden</json:string></affiliations></json:item><json:item><name>Gun‐Marie Hariz MS</name><affiliations><json:string>Department of Rehabilitation Medicine, University Hospital, Umeéa, Sweden</json:string></affiliations></json:item><json:item><name>Markku Fagerlund MD, PhD</name><affiliations><json:string>Department of Neuroradiology, University Hospital, Umeéa, Sweden</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Deep brain stimulation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Subthalamic nucleus</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Disability</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item></subject><language><json:string>eng</json:string></language><abstract>We report a patient with advanced Parkinson's disease, including severe and frequent off periods with freezing of gait, moderate dysphonia, and some cognitive impairment, who underwent bilateral subthalamic nucleus (STN) stimulation. 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The patient was followed for 1 year after surgery, showing persistent good mobility without off periods and without freezing, which reverted completely when stopping the stimulation. There was deterioration of cognition as well as increased aphonia and drooling, all of which remained when the stimulation was turned off. The striking improvement in motor symptoms following STN stimulation was not paralleled by improvement in disability, probably as a result of a cognitive decline, suggesting a diagnosis of Parkinson's disease with dementia. 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The patient was followed for 1 year after surgery, showing persistent good mobility without off periods and without freezing, which reverted completely when stopping the stimulation. There was deterioration of cognition as well as increased aphonia and drooling, all of which remained when the stimulation was turned off. The striking improvement in motor symptoms following STN stimulation was not paralleled by improvement in disability, probably as a result of a cognitive decline, suggesting a diagnosis of Parkinson's disease with dementia. We conclude that chronic STN stimulation is efficient in alleviating akinetic motor symptoms including gait freezing; this surgery should be offered before patients start to exhibit speech or cognitive disturbances.</abstract><subject lang="en"><genre>Keywords</genre><topic>Deep brain stimulation</topic><topic>Subthalamic nucleus</topic><topic>Disability</topic><topic>Parkinson's disease</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2000</date><detail type="volume"><caption>vol.</caption><number>15</number></detail><detail type="issue"><caption>no.</caption><number>1</number></detail><extent unit="pages"><start>136</start><end>139</end><total>4</total></extent></part></relatedItem><identifier type="istex">DCCCED9930270C4BE7443CE7F93CA3FE81FCDCE8</identifier><identifier type="DOI">10.1002/1531-8257(200001)15:1<136::AID-MDS1021>3.0.CO;2-5</identifier><identifier type="ArticleID">MDS1021</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2000 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>John Wiley & Sons, Inc.</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= Bilateral subthalamic nucleus stimulation in a parkinsonian patient with preoperative deficits in speech and cognition: Persistent improvement in mobility but increased dependency: A case study
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