A blessing in disguise: Resolution of tardive dyskinesia with development of cervical myelitis
Identifieur interne : 003146 ( Istex/Corpus ); précédent : 003145; suivant : 003147A blessing in disguise: Resolution of tardive dyskinesia with development of cervical myelitis
Auteurs : Erle Chuen-Hian Lim ; Einar P. V. Wilder-Smith ; Raymond Chee-Seong SeetSource :
- Movement Disorders [ 0885-3185 ] ; 2006-01.
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Abstract
Tardive dyskinesia (TD), which is frequently seen in patients treated with dopamine receptor blocking agents, is difficult to manage. We report on a young Chinese man with bipolar disorder who developed TD after haloperidol treatment, involving the trunk, limbs, and orofacial area. TD persisted despite switching to atypical antipsychotic agents and treatment with valproate, benzodiazepines, and tetrabenazine. Resolution only occurred years later when he developed quadriplegia arising from infective myelitis of the cervical cord (C4–5). He had concomitant vertebral osteomyelitis, which was successfully treated with intravenous antibiotics. With intensive rehabilitation, he recovered the use of his limbs, but had no recurrence of TD. We attribute the resolution of orofacial dyskinesias with a cervical lesion to the interconnections between the orofacial area and cervical spine via the trigeminal nucleus (which has fibers descending as far caudally as C6), as well as to resetting of cortical maps. © 2005 Movement Disorder Society
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DOI: 10.1002/mds.20715
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We attribute the resolution of orofacial dyskinesias with a cervical lesion to the interconnections between the orofacial area and cervical spine via the trigeminal nucleus (which has fibers descending as far caudally as C6), as well as to resetting of cortical maps. © 2005 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Erle Chuen‐Hian Lim MMed(Int Med)</name><affiliations><json:string>Division of Neurology, National University Hospital, Singapore</json:string></affiliations></json:item><json:item><name>Einar P.V. 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Resolution of dyskinesia with onset of cervical myelitis. Patient is seen after having undergone physical rehabilitation. This video presentation has been abbreviated. The full version will appear on theMovementDisorders DVD Supplement, which is issued bi‐annually. </caption></supportingInfoItem></supportingInformation><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Tardive dyskinesia (TD), which is frequently seen in patients treated with dopamine receptor blocking agents, is difficult to manage. We report on a young Chinese man with bipolar disorder who developed TD after haloperidol treatment, involving the trunk, limbs, and orofacial area. TD persisted despite switching to atypical antipsychotic agents and treatment with valproate, benzodiazepines, and tetrabenazine. Resolution only occurred years later when he developed quadriplegia arising from infective myelitis of the cervical cord (C4–5). He had concomitant vertebral osteomyelitis, which was successfully treated with intravenous antibiotics. With intensive rehabilitation, he recovered the use of his limbs, but had no recurrence of TD. We attribute the resolution of orofacial dyskinesias with a cervical lesion to the interconnections between the orofacial area and cervical spine via the trigeminal nucleus (which has fibers descending as far caudally as C6), as well as to resetting of cortical maps. © 2005 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>A blessing in disguise: Resolution of tardive dyskinesia with development of cervical myelitis</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Blessing in Disguise</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>A blessing in disguise: Resolution of tardive dyskinesia with development of cervical myelitis</title></titleInfo><name type="personal"><namePart type="given">Erle Chuen‐Hian</namePart><namePart type="family">Lim</namePart><namePart type="termsOfAddress">MMed(Int Med)</namePart><affiliation>Division of Neurology, National University Hospital, Singapore</affiliation><description>Correspondence: National University Hospital, 5 Lower Kent Ridge Road, 119074 Singapore</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Einar P.V.</namePart><namePart type="family">Wilder‐Smith</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Division of Neurology, National University Hospital, Singapore</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Raymond Chee‐Seong</namePart><namePart type="family">Seet</namePart><namePart type="termsOfAddress">MRCP</namePart><affiliation>Division of Neurology, National University Hospital, Singapore</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">shortCommunication</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2006-01</dateIssued><dateCaptured encoding="w3cdtf">2005-05-10</dateCaptured><dateValid encoding="w3cdtf">2005-06-28</dateValid><copyrightDate encoding="w3cdtf">2006</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="references">15</extent><extent unit="words">2102</extent></physicalDescription><abstract lang="en">Tardive dyskinesia (TD), which is frequently seen in patients treated with dopamine receptor blocking agents, is difficult to manage. We report on a young Chinese man with bipolar disorder who developed TD after haloperidol treatment, involving the trunk, limbs, and orofacial area. TD persisted despite switching to atypical antipsychotic agents and treatment with valproate, benzodiazepines, and tetrabenazine. Resolution only occurred years later when he developed quadriplegia arising from infective myelitis of the cervical cord (C4–5). He had concomitant vertebral osteomyelitis, which was successfully treated with intravenous antibiotics. With intensive rehabilitation, he recovered the use of his limbs, but had no recurrence of TD. We attribute the resolution of orofacial dyskinesias with a cervical lesion to the interconnections between the orofacial area and cervical spine via the trigeminal nucleus (which has fibers descending as far caudally as C6), as well as to resetting of cortical maps. © 2005 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>resolution</topic><topic>tardive dyskinesia</topic><topic>cervical</topic><topic>myelitis</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><note type="content"> This article includes Supplementary Video, available online at http://www.interscience.wiley.com/jpages/0885‐3185/suppmat .Supporting Info Item: Initial presentation of tardive dyskinesia. Resolution of dyskinesia with onset of cervical myelitis. Patient is seen after having undergone physical rehabilitation. This video presentation has been abbreviated. The full version will appear on theMovementDisorders DVD Supplement, which is issued bi‐annually. - </note><subject><genre>article category</genre><topic>Video Brief</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>21</number></detail><detail type="issue"><caption>no.</caption><number>1</number></detail><extent unit="pages"><start>120</start><end>122</end><total>4</total></extent></part></relatedItem><identifier type="istex">AA7EC8B3A66CE3B2012280036B75D03C4BB38C0F</identifier><identifier type="DOI">10.1002/mds.20715</identifier><identifier type="ArticleID">MDS20715</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2005 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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