Neurosurgical treatment of tremor in mitochondrial encephalopathy
Identifieur interne : 003102 ( Istex/Corpus ); précédent : 003101; suivant : 003103Neurosurgical treatment of tremor in mitochondrial encephalopathy
Auteurs : Norbert Kovacs ; Endre Pal ; Istvan Balas ; Jozsef Janszky ; Ferenc Nagy ; Hajnalka MerkliSource :
- Movement Disorders [ 0885-3185 ] ; 2006-12.
English descriptors
Abstract
A 53‐year‐old woman underwent several ischemic stroke‐like episodes and later developed incomplete, bilateral ophthalmoplegia, left vision deterioration, and bilateral tremor. The clinical course, laboratory data, and muscle histology led to a diagnosis of mitochondrial encephalomyopathy. No other etiology could be identified in the background of her disabling bilateral postural–kinetic tremor. As this tremor did not respond to pharmacological therapy, left thalamotomy and subsequently right thalamic deep brain stimulator (DBS) implantation were performed, which resulted in an excellent clinical outcome. The Fahn–Tolosa–Marin Tremor Rating Scale improved from 110 to 11 points. This case suggests that the rare tremor caused by mitochondrial encephalopathy may be treated long‐term with either thalamotomy or thalamic DBS implantation. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.21128
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ISTEX:C797028743EB2151E9AFC862F6C4C458A5B0070BLe document en format XML
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The clinical course, laboratory data, and muscle histology led to a diagnosis of mitochondrial encephalomyopathy. No other etiology could be identified in the background of her disabling bilateral postural–kinetic tremor. As this tremor did not respond to pharmacological therapy, left thalamotomy and subsequently right thalamic deep brain stimulator (DBS) implantation were performed, which resulted in an excellent clinical outcome. The Fahn–Tolosa–Marin Tremor Rating Scale improved from 110 to 11 points. This case suggests that the rare tremor caused by mitochondrial encephalopathy may be treated long‐term with either thalamotomy or thalamic DBS implantation. © 2006 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Norbert Kovacs MD</name><affiliations><json:string>Department of Neurology, University of Pecs, Pecs, Hungary</json:string></affiliations></json:item><json:item><name>Endre Pal MD, PhD</name><affiliations><json:string>Department of Neurology, University of Pecs, Pecs, Hungary</json:string></affiliations></json:item><json:item><name>Istvan Balas MD, PhD</name><affiliations><json:string>Department of Neurosurgery, University of Pecs, Pecs, Hungary</json:string></affiliations></json:item><json:item><name>Jozsef Janszky MD, PhD</name><affiliations><json:string>Department of Neurology, University of Pecs, Pecs, Hungary</json:string></affiliations></json:item><json:item><name>Ferenc Nagy MD, PhD</name><affiliations><json:string>Department of Neurology, University of Pecs, Pecs, Hungary</json:string></affiliations></json:item><json:item><name>Hajnalka Merkli MD</name><affiliations><json:string>Department of Neurology, University of Pecs, Pecs, Hungary</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>deep brain stimulation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>mitochondrial encephalopathy</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>thalamotomy</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>tremor</value></json:item></subject><language><json:string>eng</json:string></language><abstract>A 53‐year‐old woman underwent several ischemic stroke‐like episodes and later developed incomplete, bilateral ophthalmoplegia, left vision deterioration, and bilateral tremor. 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This case suggests that the rare tremor caused by mitochondrial encephalopathy may be treated long‐term with either thalamotomy or thalamic DBS implantation. © 2006 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>deep brain stimulation</term></item><item><term>mitochondrial encephalopathy</term></item><item><term>thalamotomy</term></item><item><term>tremor</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Brief Report</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2005-11-28">Received</change><change when="2006-06-18">Registration</change><change when="2006-12">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/C797028743EB2151E9AFC862F6C4C458A5B0070B/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="subtitle">Official Journal of the Movement Disorder Society</title><title type="short">Mov. 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Before the left thalamotomy. Segment 2 . Two days before right thalamic deep brain stimulator implantation. Segment 3 .Three years after the implantation, deep brain stimulation turned off. Segment 4 .Three years after the implantation, deep brain stimulation turned on. </caption></supportingInfoItem></supportingInformation><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>A 53‐year‐old woman underwent several ischemic stroke‐like episodes and later developed incomplete, bilateral ophthalmoplegia, left vision deterioration, and bilateral tremor. The clinical course, laboratory data, and muscle histology led to a diagnosis of mitochondrial encephalomyopathy. No other etiology could be identified in the background of her disabling bilateral postural–kinetic tremor. As this tremor did not respond to pharmacological therapy, left thalamotomy and subsequently right thalamic deep brain stimulator (DBS) implantation were performed, which resulted in an excellent clinical outcome. The Fahn–Tolosa–Marin Tremor Rating Scale improved from 110 to 11 points. This case suggests that the rare tremor caused by mitochondrial encephalopathy may be treated long‐term with either thalamotomy or thalamic DBS implantation. © 2006 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Neurosurgical treatment of tremor in mitochondrial encephalopathy</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Tremor in Mitochondrial Disorder</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Neurosurgical treatment of tremor in mitochondrial encephalopathy</title></titleInfo><name type="personal"><namePart type="given">Norbert</namePart><namePart type="family">Kovacs</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University of Pecs, Pecs, Hungary</affiliation><description>Correspondence: Department of Neurology, University of Pecs, H‐7623, Pecs, Ret utca 2, Hungary</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Endre</namePart><namePart type="family">Pal</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurology, University of Pecs, Pecs, Hungary</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Istvan</namePart><namePart type="family">Balas</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurosurgery, University of Pecs, Pecs, Hungary</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jozsef</namePart><namePart type="family">Janszky</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurology, University of Pecs, Pecs, Hungary</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ferenc</namePart><namePart type="family">Nagy</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurology, University of Pecs, Pecs, Hungary</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hajnalka</namePart><namePart type="family">Merkli</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University of Pecs, Pecs, Hungary</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2006-12</dateIssued><dateCaptured encoding="w3cdtf">2005-11-28</dateCaptured><dateValid encoding="w3cdtf">2006-06-18</dateValid><copyrightDate encoding="w3cdtf">2006</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">2</extent><extent unit="references">7</extent><extent unit="words">2081</extent></physicalDescription><abstract lang="en">A 53‐year‐old woman underwent several ischemic stroke‐like episodes and later developed incomplete, bilateral ophthalmoplegia, left vision deterioration, and bilateral tremor. The clinical course, laboratory data, and muscle histology led to a diagnosis of mitochondrial encephalomyopathy. No other etiology could be identified in the background of her disabling bilateral postural–kinetic tremor. As this tremor did not respond to pharmacological therapy, left thalamotomy and subsequently right thalamic deep brain stimulator (DBS) implantation were performed, which resulted in an excellent clinical outcome. The Fahn–Tolosa–Marin Tremor Rating Scale improved from 110 to 11 points. This case suggests that the rare tremor caused by mitochondrial encephalopathy may be treated long‐term with either thalamotomy or thalamic DBS implantation. © 2006 Movement Disorder Society</abstract><note type="funding">OTKA - No. T043005; </note><subject lang="en"><genre>Keywords</genre><topic>deep brain stimulation</topic><topic>mitochondrial encephalopathy</topic><topic>thalamotomy</topic><topic>tremor</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><note type="content"> This article includes Supplementary Video, available online at http://www.interscience.wiley.com/jpages/0885‐3185/suppmatSupporting Info Item: Segment 1 . Before the left thalamotomy. Segment 2 . Two days before right thalamic deep brain stimulator implantation. Segment 3 .Three years after the implantation, deep brain stimulation turned off. Segment 4 .Three years after the implantation, deep brain stimulation turned on. - </note><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>21</number></detail><detail type="issue"><caption>no.</caption><number>12</number></detail><extent unit="pages"><start>2227</start><end>2230</end><total>4</total></extent></part></relatedItem><identifier type="istex">C797028743EB2151E9AFC862F6C4C458A5B0070B</identifier><identifier type="DOI">10.1002/mds.21128</identifier><identifier type="ArticleID">MDS21128</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2006 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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