Movement Disorders (revue)

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Ultrasound‐guided injection of the iliopsoas muscle with botulinum toxin in camptocormia

Identifieur interne : 003004 ( Istex/Corpus ); précédent : 003003; suivant : 003005

Ultrasound‐guided injection of the iliopsoas muscle with botulinum toxin in camptocormia

Auteurs : Rainer Von Coelln ; Armin Raible ; Thomas Gasser ; Friedrich Asmus

Source :

RBID : ISTEX:F7DC47417E5C6A6F620009971F8A38AC343F2D16

English descriptors

Abstract

Camptocormia is characterized by an abnormal posture of the trunk with pronounced flexion of the thoraco‐lumbar spine during standing and walking, which abates in a supine position. Treatment options for camptocormia are limited and mostly futile. Here, we report on the ultrasound‐guided ventral injection of botulinum toxin A (BTX) into deep portions of the iliopsoas muscle in four parkinsonian patients with camptocormia as chief complaint. Using this novel and safe application technique, all patients received 500–1,500 MU of BTX per side in 4–6 month intervals. Treatment was generally well tolerated. At the highest dose, all patients complained of mild weakness of hip flexion. Standardized physical exam at follow‐up visits, as well as self‐assessment of patients, failed to show a relevant and lasting improvement of posture. In conclusion, injection of BTX into the iliopsoas does not appear to be a promising approach for the treatment of parkinsonism‐associated camptocormia. © 2008 Movement Disorder Society

Url:
DOI: 10.1002/mds.21967

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<title>Ultrasound‐guided injection of the iliopsoas muscle with botulinum toxin in camptocormia</title>
</titleInfo>
<name type="personal">
<namePart type="given">Rainer</namePart>
<namePart type="family">von Coelln</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Armin</namePart>
<namePart type="family">Raible</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Department of Internal Medicine I, University of Tuebingen,Tuebingen, Germany</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Thomas</namePart>
<namePart type="family">Gasser</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Friedrich</namePart>
<namePart type="family">Asmus</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany</affiliation>
<description>Correspondence: Dystonia and Botulinumtoxin Clinic, Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, Otfried‐Muller Str. 27, 4th floor, D‐72076 Tuebingen, Germany</description>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
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<publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<place>
<placeTerm type="text">Hoboken</placeTerm>
</place>
<dateIssued encoding="w3cdtf">2008-04-30</dateIssued>
<dateCaptured encoding="w3cdtf">2007-11-05</dateCaptured>
<dateValid encoding="w3cdtf">2008-01-13</dateValid>
<copyrightDate encoding="w3cdtf">2008</copyrightDate>
</originInfo>
<language>
<languageTerm type="code" authority="rfc3066">en</languageTerm>
<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
</language>
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<internetMediaType>text/html</internetMediaType>
<extent unit="figures">1</extent>
<extent unit="tables">1</extent>
<extent unit="references">15</extent>
<extent unit="words">2567</extent>
</physicalDescription>
<abstract lang="en">Camptocormia is characterized by an abnormal posture of the trunk with pronounced flexion of the thoraco‐lumbar spine during standing and walking, which abates in a supine position. Treatment options for camptocormia are limited and mostly futile. Here, we report on the ultrasound‐guided ventral injection of botulinum toxin A (BTX) into deep portions of the iliopsoas muscle in four parkinsonian patients with camptocormia as chief complaint. Using this novel and safe application technique, all patients received 500–1,500 MU of BTX per side in 4–6 month intervals. Treatment was generally well tolerated. At the highest dose, all patients complained of mild weakness of hip flexion. Standardized physical exam at follow‐up visits, as well as self‐assessment of patients, failed to show a relevant and lasting improvement of posture. In conclusion, injection of BTX into the iliopsoas does not appear to be a promising approach for the treatment of parkinsonism‐associated camptocormia. © 2008 Movement Disorder Society</abstract>
<subject lang="en">
<genre>Keywords</genre>
<topic>iliopsoas</topic>
<topic>psoas major</topic>
<topic>camptocormia</topic>
<topic>botulinum toxin A</topic>
<topic>ultrasound‐guidance</topic>
</subject>
<relatedItem type="host">
<titleInfo>
<title>Movement Disorders</title>
</titleInfo>
<titleInfo type="abbreviated">
<title>Mov. Disord.</title>
</titleInfo>
<subject>
<genre>article category</genre>
<topic>Brief Report</topic>
</subject>
<identifier type="ISSN">0885-3185</identifier>
<identifier type="eISSN">1531-8257</identifier>
<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
<identifier type="PublisherID">MDS</identifier>
<part>
<date>2008</date>
<detail type="volume">
<caption>vol.</caption>
<number>23</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>6</number>
</detail>
<extent unit="pages">
<start>889</start>
<end>892</end>
<total>4</total>
</extent>
</part>
</relatedItem>
<identifier type="istex">F7DC47417E5C6A6F620009971F8A38AC343F2D16</identifier>
<identifier type="DOI">10.1002/mds.21967</identifier>
<identifier type="ArticleID">MDS21967</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2008 Movement Disorder Society</accessCondition>
<recordInfo>
<recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin>
<recordContentSource>WILEY</recordContentSource>
</recordInfo>
</mods>
</metadata>
<serie></serie>
</istex>
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