Fulminant Lewy body disease
Identifieur interne : 002F96 ( Istex/Corpus ); précédent : 002F95; suivant : 002F97Fulminant Lewy body disease
Auteurs : Isabelle Momjian-Mayor ; Gian Paolo Pizzolato ; Karim Burkhardt ; Theodor Landis ; Alessandra Coeytaux ; Pierre R. BurkhardSource :
- Movement Disorders [ 0885-3185 ] ; 2006-10.
English descriptors
- KwdEn :
Abstract
The clinical distinction between Parkinson's disease (PD) with dementia (PDD) and dementia with Lewy bodies (DLB) is challenged by most neuropathological studies showing nearly identical changes in both conditions. We report an unusual case of PD evolving into a rapidly progressive dementia leading to death within 3 months that showed nearly all clinical features of DLB. At autopsy, numerous Lewy bodies and Lewy neurites were found in several areas of the brainstem, the limbic system, and the neocortex, consistent with pure DLB. This case demonstrates that Lewy body disease may exhibit a dramatic course without any coexisting pathology and exemplifies that PD, PDD, and DLB may sometimes represent sequential, yet overlapping, phenotypes of a same clinicopathological entity. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.21034
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ISTEX:30B3B414DC73EA5DBB0EA2A45B9A32BB88740277Le document en format XML
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We report an unusual case of PD evolving into a rapidly progressive dementia leading to death within 3 months that showed nearly all clinical features of DLB. At autopsy, numerous Lewy bodies and Lewy neurites were found in several areas of the brainstem, the limbic system, and the neocortex, consistent with pure DLB. 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We report an unusual case of PD evolving into a rapidly progressive dementia leading to death within 3 months that showed nearly all clinical features of DLB. At autopsy, numerous Lewy bodies and Lewy neurites were found in several areas of the brainstem, the limbic system, and the neocortex, consistent with pure DLB. 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We report an unusual case of PD evolving into a rapidly progressive dementia leading to death within 3 months that showed nearly all clinical features of DLB. At autopsy, numerous Lewy bodies and Lewy neurites were found in several areas of the brainstem, the limbic system, and the neocortex, consistent with pure DLB. This case demonstrates that Lewy body disease may exhibit a dramatic course without any coexisting pathology and exemplifies that PD, PDD, and DLB may sometimes represent sequential, yet overlapping, phenotypes of a same clinicopathological entity. © 2006 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>Parkinson's disease</topic><topic>dementia</topic><topic>Lewy body</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. 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|étape= Corpus
|type= RBID
|clé= ISTEX:30B3B414DC73EA5DBB0EA2A45B9A32BB88740277
|texte= Fulminant Lewy body disease
}}
| This area was generated with Dilib version V0.6.23. |  |