Movement Disorders (revue)

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Dystonia in Wilson's disease

Identifieur interne : 002E86 ( Istex/Corpus ); précédent : 002E85; suivant : 002E87

Dystonia in Wilson's disease

Auteurs : Marina Svetel ; Duško Kozi ; Elka Stefanova ; Robert Semnic ; Nataša Dragaševi ; Vladimir S. Kosti

Source :

RBID : ISTEX:EA68B9EB7F07B70B244216AC469250E8F1920C14

English descriptors

Abstract

The frequency and type of dystonic movements, as well as brain abnormalities, as depicted with magnetic resonance imaging (MRI), which might correlate with dystonia, were studied in 27 consecutive patients with a neurologic form of Wilson's disease (WD) and optimized treatment. Dystonia was found in 10 patients (37%), being generalized in half of them, while two patients had segmental, two patients multifocal dystonia, and one patient bilateral foot dystonia. Dystonia was a presenting sign in four patients and developed later in the course of the disease in six patients, despite the administered therapy for WD. Putamen was the only structure significantly more frequently lesioned in dystonic (80%) in comparison to WD patients without dystonia (24%), suggesting a relation between abnormalities in this brain region and dystonic movements in WD. © 2001 Movement Disorder Society.

Url:
DOI: 10.1002/mds.1118

Links to Exploration step

ISTEX:EA68B9EB7F07B70B244216AC469250E8F1920C14

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<titleInfo lang="en">
<title>Dystonia in Wilson's disease</title>
</titleInfo>
<titleInfo type="abbreviated" lang="en">
<title>Wilson's Disease and Dystonia</title>
</titleInfo>
<titleInfo type="alternative" contentType="CDATA" lang="en">
<title>Dystonia in Wilson's disease</title>
</titleInfo>
<name type="personal">
<namePart type="given">Marina</namePart>
<namePart type="family">Svetel</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Institute of Neurology CCS, Belgrade, Yugoslavia</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Duško</namePart>
<namePart type="family">Kozić</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>MRI Center, Sremska Kamenica, Yugoslavia</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Elka</namePart>
<namePart type="family">Stefanova</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Institute of Neurology CCS, Belgrade, Yugoslavia</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Robert</namePart>
<namePart type="family">Semnic</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>MRI Center, Sremska Kamenica, Yugoslavia</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Nataša</namePart>
<namePart type="family">Dragaševič</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Institute of Neurology CCS, Belgrade, Yugoslavia</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Vladimir S.</namePart>
<namePart type="family">Kostič</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Institute of Neurology CCS, Belgrade, Yugoslavia</affiliation>
<description>Correspondence: Institute of Neurology CCS, ul. Subotica 6, 1 1000 Belgrade, Yugoslavia</description>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<typeOfResource>text</typeOfResource>
<genre authority="originalCategForm">shortCommunication</genre>
<originInfo>
<publisher>John Wiley & Sons, Inc.</publisher>
<place>
<placeTerm type="text">New York</placeTerm>
</place>
<dateIssued encoding="w3cdtf">2001-07</dateIssued>
<dateCaptured encoding="w3cdtf">2000-10-06</dateCaptured>
<dateValid encoding="w3cdtf">2001-01-22</dateValid>
<copyrightDate encoding="w3cdtf">2001</copyrightDate>
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<languageTerm type="code" authority="rfc3066">en</languageTerm>
<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
</language>
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<internetMediaType>text/html</internetMediaType>
<extent unit="figures">1</extent>
<extent unit="tables">3</extent>
<extent unit="references">26</extent>
<extent unit="words">2369</extent>
</physicalDescription>
<abstract lang="en">The frequency and type of dystonic movements, as well as brain abnormalities, as depicted with magnetic resonance imaging (MRI), which might correlate with dystonia, were studied in 27 consecutive patients with a neurologic form of Wilson's disease (WD) and optimized treatment. Dystonia was found in 10 patients (37%), being generalized in half of them, while two patients had segmental, two patients multifocal dystonia, and one patient bilateral foot dystonia. Dystonia was a presenting sign in four patients and developed later in the course of the disease in six patients, despite the administered therapy for WD. Putamen was the only structure significantly more frequently lesioned in dystonic (80%) in comparison to WD patients without dystonia (24%), suggesting a relation between abnormalities in this brain region and dystonic movements in WD. © 2001 Movement Disorder Society.</abstract>
<subject lang="en">
<genre>Keywords</genre>
<topic>Wilson's disease</topic>
<topic>dystonia</topic>
<topic>MRI</topic>
<topic>putamen</topic>
</subject>
<relatedItem type="host">
<titleInfo>
<title>Movement Disorders</title>
<subTitle>Official Journal of the Movement Disorder Society</subTitle>
</titleInfo>
<titleInfo type="abbreviated">
<title>Mov. Disord.</title>
</titleInfo>
<subject>
<genre>article category</genre>
<topic>Brief Report</topic>
</subject>
<identifier type="ISSN">0885-3185</identifier>
<identifier type="eISSN">1531-8257</identifier>
<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
<identifier type="PublisherID">MDS</identifier>
<part>
<date>2001</date>
<detail type="volume">
<caption>vol.</caption>
<number>16</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>4</number>
</detail>
<extent unit="pages">
<start>719</start>
<end>723</end>
<total>5</total>
</extent>
</part>
</relatedItem>
<identifier type="istex">EA68B9EB7F07B70B244216AC469250E8F1920C14</identifier>
<identifier type="DOI">10.1002/mds.1118</identifier>
<identifier type="ArticleID">MDS1118</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2001 Movement Disorder Society</accessCondition>
<recordInfo>
<recordOrigin>John Wiley & Sons, Inc.</recordOrigin>
<recordContentSource>WILEY</recordContentSource>
</recordInfo>
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