Dystonia in Wilson's disease
Identifieur interne : 002E86 ( Istex/Corpus ); précédent : 002E85; suivant : 002E87Dystonia in Wilson's disease
Auteurs : Marina Svetel ; Duško Kozi ; Elka Stefanova ; Robert Semnic ; Nataša Dragaševi ; Vladimir S. KostiSource :
- Movement Disorders [ 0885-3185 ] ; 2001-07.
English descriptors
- KwdEn :
Abstract
The frequency and type of dystonic movements, as well as brain abnormalities, as depicted with magnetic resonance imaging (MRI), which might correlate with dystonia, were studied in 27 consecutive patients with a neurologic form of Wilson's disease (WD) and optimized treatment. Dystonia was found in 10 patients (37%), being generalized in half of them, while two patients had segmental, two patients multifocal dystonia, and one patient bilateral foot dystonia. Dystonia was a presenting sign in four patients and developed later in the course of the disease in six patients, despite the administered therapy for WD. Putamen was the only structure significantly more frequently lesioned in dystonic (80%) in comparison to WD patients without dystonia (24%), suggesting a relation between abnormalities in this brain region and dystonic movements in WD. © 2001 Movement Disorder Society.
Url:
DOI: 10.1002/mds.1118
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<front><div type="abstract" xml:lang="en">The frequency and type of dystonic movements, as well as brain abnormalities, as depicted with magnetic resonance imaging (MRI), which might correlate with dystonia, were studied in 27 consecutive patients with a neurologic form of Wilson's disease (WD) and optimized treatment. Dystonia was found in 10 patients (37%), being generalized in half of them, while two patients had segmental, two patients multifocal dystonia, and one patient bilateral foot dystonia. Dystonia was a presenting sign in four patients and developed later in the course of the disease in six patients, despite the administered therapy for WD. Putamen was the only structure significantly more frequently lesioned in dystonic (80%) in comparison to WD patients without dystonia (24%), suggesting a relation between abnormalities in this brain region and dystonic movements in WD. © 2001 Movement Disorder Society.</div>
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<namePart type="family">Dragaševič</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Institute of Neurology CCS, Belgrade, Yugoslavia</affiliation>
<role><roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal"><namePart type="given">Vladimir S.</namePart>
<namePart type="family">Kostič</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Institute of Neurology CCS, Belgrade, Yugoslavia</affiliation>
<description>Correspondence: Institute of Neurology CCS, ul. Subotica 6, 1 1000 Belgrade, Yugoslavia</description>
<role><roleTerm type="text">author</roleTerm>
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<typeOfResource>text</typeOfResource>
<genre authority="originalCategForm">shortCommunication</genre>
<originInfo><publisher>John Wiley & Sons, Inc.</publisher>
<place><placeTerm type="text">New York</placeTerm>
</place>
<dateIssued encoding="w3cdtf">2001-07</dateIssued>
<dateCaptured encoding="w3cdtf">2000-10-06</dateCaptured>
<dateValid encoding="w3cdtf">2001-01-22</dateValid>
<copyrightDate encoding="w3cdtf">2001</copyrightDate>
</originInfo>
<language><languageTerm type="code" authority="rfc3066">en</languageTerm>
<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
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<extent unit="figures">1</extent>
<extent unit="tables">3</extent>
<extent unit="references">26</extent>
<extent unit="words">2369</extent>
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<abstract lang="en">The frequency and type of dystonic movements, as well as brain abnormalities, as depicted with magnetic resonance imaging (MRI), which might correlate with dystonia, were studied in 27 consecutive patients with a neurologic form of Wilson's disease (WD) and optimized treatment. Dystonia was found in 10 patients (37%), being generalized in half of them, while two patients had segmental, two patients multifocal dystonia, and one patient bilateral foot dystonia. Dystonia was a presenting sign in four patients and developed later in the course of the disease in six patients, despite the administered therapy for WD. Putamen was the only structure significantly more frequently lesioned in dystonic (80%) in comparison to WD patients without dystonia (24%), suggesting a relation between abnormalities in this brain region and dystonic movements in WD. © 2001 Movement Disorder Society.</abstract>
<subject lang="en"><genre>Keywords</genre>
<topic>Wilson's disease</topic>
<topic>dystonia</topic>
<topic>MRI</topic>
<topic>putamen</topic>
</subject>
<relatedItem type="host"><titleInfo><title>Movement Disorders</title>
<subTitle>Official Journal of the Movement Disorder Society</subTitle>
</titleInfo>
<titleInfo type="abbreviated"><title>Mov. Disord.</title>
</titleInfo>
<subject><genre>article category</genre>
<topic>Brief Report</topic>
</subject>
<identifier type="ISSN">0885-3185</identifier>
<identifier type="eISSN">1531-8257</identifier>
<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
<identifier type="PublisherID">MDS</identifier>
<part><date>2001</date>
<detail type="volume"><caption>vol.</caption>
<number>16</number>
</detail>
<detail type="issue"><caption>no.</caption>
<number>4</number>
</detail>
<extent unit="pages"><start>719</start>
<end>723</end>
<total>5</total>
</extent>
</part>
</relatedItem>
<identifier type="istex">EA68B9EB7F07B70B244216AC469250E8F1920C14</identifier>
<identifier type="DOI">10.1002/mds.1118</identifier>
<identifier type="ArticleID">MDS1118</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2001 Movement Disorder Society</accessCondition>
<recordInfo><recordOrigin>John Wiley & Sons, Inc.</recordOrigin>
<recordContentSource>WILEY</recordContentSource>
</recordInfo>
</mods>
</metadata>
<serie></serie>
</istex>
</record>
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