Basal ganglia physiology and deep brain stimulation
Identifieur interne : 002D47 ( Istex/Corpus ); précédent : 002D46; suivant : 002D48Basal ganglia physiology and deep brain stimulation
Auteurs : Andres M. Lozano ; Brian J. Snyder ; Clement Hamani ; William D. Hutchison ; Jonathan O. DostrovskySource :
- Movement Disorders [ 0885-3185 ] ; 2010.
English descriptors
- KwdEn :
Abstract
Despite improvements in anatomic imaging of the basal ganglia, microelectrode recording is still an invaluable tool in locating appropriate targets for neurosurgical intervention. These recording also provide an unparalleled opportunity to study the pathophysiological aspects of diseases. This article reviews the principles of microelectrode recording in functional neurosurgery and discusses the pathologic neurophysiologic findings commonly encountered. It also highlights some of the potential mechanisms of action of both dopaminergic drugs and deep brain stimulation. In addition we review the recent work on pedunculopontine nucleus neurophysiology and trials of deep brain stimulation in that region for gait disturbances in Parkinson's disease. © 2010 Movement Disorder Society
Url:
DOI: 10.1002/mds.22714
Links to Exploration step
ISTEX:C70B0DF7DB3629CAAA9FB53541A86B16CEFEAF0FLe document en format XML
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These recording also provide an unparalleled opportunity to study the pathophysiological aspects of diseases. This article reviews the principles of microelectrode recording in functional neurosurgery and discusses the pathologic neurophysiologic findings commonly encountered. It also highlights some of the potential mechanisms of action of both dopaminergic drugs and deep brain stimulation. In addition we review the recent work on pedunculopontine nucleus neurophysiology and trials of deep brain stimulation in that region for gait disturbances in Parkinson's disease. © 2010 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Andres M. 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xml:id="kwd1">deep brain stimulation</keyword><keyword xml:id="kwd2">globus pallidus</keyword><keyword xml:id="kwd3">microelectrode recording</keyword><keyword xml:id="kwd4">Parkinson's disease</keyword><keyword xml:id="kwd5">subthalamic nucleus</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Despite improvements in anatomic imaging of the basal ganglia, microelectrode recording is still an invaluable tool in locating appropriate targets for neurosurgical intervention. These recording also provide an unparalleled opportunity to study the pathophysiological aspects of diseases. This article reviews the principles of microelectrode recording in functional neurosurgery and discusses the pathologic neurophysiologic findings commonly encountered. It also highlights some of the potential mechanisms of action of both dopaminergic drugs and deep brain stimulation. In addition we review the recent work on pedunculopontine nucleus neurophysiology and trials of deep brain stimulation in that region for gait disturbances in Parkinson's disease. © 2010 Movement Disorder Society</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><p>Potential conflict of interest: None reported.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Basal ganglia physiology and deep brain stimulation</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Basal Ganglia Physiology and DBS</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Basal ganglia physiology and deep brain stimulation</title></titleInfo><name type="personal"><namePart type="given">Andres M.</namePart><namePart type="family">Lozano</namePart><namePart type="termsOfAddress">FRCSC, MD, PhD</namePart><affiliation>Division of Neurosurgery, Toronto Western Hospital, University of Toronto, UHN, Toronto, Ontario, Canada</affiliation><affiliation>Toronto Western Research Institute, Toronto, Ontario, Canada</affiliation><description>Correspondence: Division of Neurosurgery, Toronto Western Hospital, 399 Bathurst Street WW 4‐447, Toronto, ON M5T2S8, Canada</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Brian J.</namePart><namePart type="family">Snyder</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Division of Neurosurgery, Toronto Western Hospital, University of Toronto, UHN, Toronto, Ontario, Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Clement</namePart><namePart type="family">Hamani</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Division of Neurosurgery, Toronto Western Hospital, University of Toronto, UHN, Toronto, Ontario, Canada</affiliation><affiliation>Toronto Western Research Institute, Toronto, Ontario, Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">William D.</namePart><namePart type="family">Hutchison</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Toronto Western Research Institute, Toronto, Ontario, Canada</affiliation><affiliation>Department of Physiology, University of Toronto, Toronto, Ontario, Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jonathan O.</namePart><namePart type="family">Dostrovsky</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Toronto Western Research Institute, Toronto, Ontario, Canada</affiliation><affiliation>Department of Physiology, University of Toronto, Toronto, Ontario, Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2010</dateIssued><dateCaptured encoding="w3cdtf">2009-12-03</dateCaptured><dateValid encoding="w3cdtf">2009-07-06</dateValid><copyrightDate encoding="w3cdtf">2010</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="references">24</extent><extent unit="words">3174</extent></physicalDescription><abstract lang="en">Despite improvements in anatomic imaging of the basal ganglia, microelectrode recording is still an invaluable tool in locating appropriate targets for neurosurgical intervention. These recording also provide an unparalleled opportunity to study the pathophysiological aspects of diseases. This article reviews the principles of microelectrode recording in functional neurosurgery and discusses the pathologic neurophysiologic findings commonly encountered. It also highlights some of the potential mechanisms of action of both dopaminergic drugs and deep brain stimulation. In addition we review the recent work on pedunculopontine nucleus neurophysiology and trials of deep brain stimulation in that region for gait disturbances in Parkinson's disease. © 2010 Movement Disorder Society</abstract><note type="content">*Potential conflict of interest: None reported.</note><subject lang="en"><genre>Keywords</genre><topic>deep brain stimulation</topic><topic>globus pallidus</topic><topic>microelectrode recording</topic><topic>Parkinson's disease</topic><topic>subthalamic nucleus</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><name type="personal"><namePart type="given">Fahn</namePart><namePart type="family">Stanley</namePart><namePart type="termsOfAddress">MD</namePart></name><name type="personal"><namePart type="given">Marder</namePart><namePart type="family">Karen</namePart><namePart type="termsOfAddress">MD</namePart></name><name type="personal"><namePart type="given">Côté</namePart><namePart type="family">Lucien</namePart><namePart type="termsOfAddress">MD</namePart></name><name type="personal"><namePart type="given">Reich</namePart><namePart type="family">Stephen G.</namePart><namePart type="termsOfAddress">MD</namePart></name><subject><genre>article category</genre><topic>Status of the Central Role of Dopamine in PD</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2010</date><detail type="title"><title>Frontiers of Science and Clinical Advances in Quality of Life in Parkinson's Disease</title></detail><detail type="volume"><caption>vol.</caption><number>25</number></detail><detail type="issue"><caption>no.</caption><number>S1</number></detail><extent unit="pages"><start>S71</start><end>S75</end><total>5</total></extent></part></relatedItem><identifier type="istex">C70B0DF7DB3629CAAA9FB53541A86B16CEFEAF0F</identifier><identifier type="DOI">10.1002/mds.22714</identifier><identifier type="ArticleID">MDS22714</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2010 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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