Teaching program for the Unified Dyskinesia Rating Scale
Identifieur interne : 002891 ( Istex/Corpus ); précédent : 002890; suivant : 002892Teaching program for the Unified Dyskinesia Rating Scale
Auteurs : Christopher G. Goetz ; John G. Nutt ; Glenn T. Stebbins ; Teresa A. ChmuraSource :
- Movement Disorders [ 0885-3185 ] ; 2009-07-15.
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Abstract
The Unified Dyskinesia Rating Scale (UDysRS) has been introduced as a comprehensive rating tool for the evaluation of dyskinesias in Parkinson's disease (PD). To enhance a uniform application, we developed a DVD‐based training program with instructions, patient examples, and a certification exercise. For training on the objective assessment of dyskinesia, seventy PD patients spanning the gamut of dyskinesias (none to severe) were videotaped during four tasks of daily living (speaking, drinking from a cup, putting on a coat, and walking). Dyskinesia severity in seven body parts was rated by 20 international movement disorder specialists using the UDysRS for impairment. Each task was also rated for disability. Inter‐rater reliability was assessed with generalized weighted kappa and intraclass correlation coefficients. For the teaching program, examples of each severity level and each body part were selected based on the criterion that they received a uniform rating (± 1 point) by at least 75% of the raters. For the certification exercise, four cases were selected to represent the four quartiles of overall objective UDysRS scores to reflect slight, mild, moderate, and severe dyskinesia. Each selection was based on the highest inter‐rater reliability score for that quartile (minimum kappa or intraclass correlation coefficient = 0.6). UDysRS ranges for certification were calculated based on the 95% confidence interval. The teaching program lasts 41 min, and the certification exercise requires 10 min (total 51 min). This training program, based on visual examples of dyskinesia and anchored in scores generated by movement disorder experts is aimed at increasing homogeneity of ratings among and within raters and centers. Large‐scale multicenter randomized clinical trials of dyskinesia treatment are strengthened by a uniform standard of scale application. © 2009 Movement Disorder Society
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DOI: 10.1002/mds.22563
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To enhance a uniform application, we developed a DVD‐based training program with instructions, patient examples, and a certification exercise. For training on the objective assessment of dyskinesia, seventy PD patients spanning the gamut of dyskinesias (none to severe) were videotaped during four tasks of daily living (speaking, drinking from a cup, putting on a coat, and walking). Dyskinesia severity in seven body parts was rated by 20 international movement disorder specialists using the UDysRS for impairment. Each task was also rated for disability. Inter‐rater reliability was assessed with generalized weighted kappa and intraclass correlation coefficients. For the teaching program, examples of each severity level and each body part were selected based on the criterion that they received a uniform rating (± 1 point) by at least 75% of the raters. For the certification exercise, four cases were selected to represent the four quartiles of overall objective UDysRS scores to reflect slight, mild, moderate, and severe dyskinesia. Each selection was based on the highest inter‐rater reliability score for that quartile (minimum kappa or intraclass correlation coefficient = 0.6). UDysRS ranges for certification were calculated based on the 95% confidence interval. The teaching program lasts 41 min, and the certification exercise requires 10 min (total 51 min). This training program, based on visual examples of dyskinesia and anchored in scores generated by movement disorder experts is aimed at increasing homogeneity of ratings among and within raters and centers. Large‐scale multicenter randomized clinical trials of dyskinesia treatment are strengthened by a uniform standard of scale application. © 2009 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Christopher G. Goetz MD</name><affiliations><json:string>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</json:string></affiliations></json:item><json:item><name>John G. Nutt MD</name><affiliations><json:string>Department of Neurology, Oregon Health Sciences University, Portland, Oregon, USA</json:string></affiliations></json:item><json:item><name>Glenn T. Stebbins PhD</name><affiliations><json:string>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</json:string></affiliations></json:item><json:item><name>Teresa A. Chmura BS</name><affiliations><json:string>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>dyskinesia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>rating scales</value></json:item></subject><language><json:string>eng</json:string></language><abstract>The Unified Dyskinesia Rating Scale (UDysRS) has been introduced as a comprehensive rating tool for the evaluation of dyskinesias in Parkinson's disease (PD). To enhance a uniform application, we developed a DVD‐based training program with instructions, patient examples, and a certification exercise. For training on the objective assessment of dyskinesia, seventy PD patients spanning the gamut of dyskinesias (none to severe) were videotaped during four tasks of daily living (speaking, drinking from a cup, putting on a coat, and walking). Dyskinesia severity in seven body parts was rated by 20 international movement disorder specialists using the UDysRS for impairment. Each task was also rated for disability. Inter‐rater reliability was assessed with generalized weighted kappa and intraclass correlation coefficients. For the teaching program, examples of each severity level and each body part were selected based on the criterion that they received a uniform rating (± 1 point) by at least 75% of the raters. For the certification exercise, four cases were selected to represent the four quartiles of overall objective UDysRS scores to reflect slight, mild, moderate, and severe dyskinesia. Each selection was based on the highest inter‐rater reliability score for that quartile (minimum kappa or intraclass correlation coefficient = 0.6). UDysRS ranges for certification were calculated based on the 95% confidence interval. The teaching program lasts 41 min, and the certification exercise requires 10 min (total 51 min). This training program, based on visual examples of dyskinesia and anchored in scores generated by movement disorder experts is aimed at increasing homogeneity of ratings among and within raters and centers. 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He has received funding from NIH, Michael J. Fox Foundation, and directs the Rush Parkinson's Disease Research Center that receives support from the Parkinson's Disease Foundation. Dr. Stebbins, Consulting and Advisory Board Membership in the past three years: Boehringer‐Ingelheim, Novartis Pharmaceuticals. He has received funding from NIH, the Michael J. Fox Foundation, the Fragile X Foundation and the Kinetics Foundation. Dr. Nutt, Consulting and Advisory Board Positions: IMPAX Laboratories, Schering‐Plough Research, Xenoport, Inc. Research funding: NIH, MJFF, Kinetics Fdn, Ceregene, and National Parkinson Foundation. Dr. Nutt directs the Movement Disorder Program at OHSU and co‐directs the PADRECC at the Portland VA.</note><note>UDysRS</note><note>Michael J Fox Foundation</note><note>EMD/Merck KGaA Pharmaceuticals</note><note>Santhera Pharmaceuticals</note><note>i3 Research Inc.</note><note>Rush Movement Disorder Program is a Parkinson's Disease Foundation Research Center</note><note>OHSU Movement Disorder Program is a National Parkinson Disease Center of Excellence</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Teaching program for the Unified Dyskinesia Rating Scale</title><author><persName><forename type="first">Christopher G.</forename><surname>Goetz</surname><roleName type="degree">MD</roleName></persName><note type="correspondence"><p>Correspondence: Department of Neurological Sciences, Rush University Medical Center, Suite 755: 1725 West Harrison Street, Chicago, IL 60612</p></note><affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</affiliation></author><author><persName><forename type="first">John G.</forename><surname>Nutt</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, Oregon Health Sciences University, Portland, Oregon, USA</affiliation></author><author><persName><forename type="first">Glenn T.</forename><surname>Stebbins</surname><roleName type="degree">PhD</roleName></persName><affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</affiliation></author><author><persName><forename type="first">Teresa A.</forename><surname>Chmura</surname><roleName type="degree">BS</roleName></persName><affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</affiliation></author></analytic><monogr><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2009-07-15"></date><biblScope unit="vol">24</biblScope><biblScope unit="issue">9</biblScope><biblScope unit="page" from="1296">1296</biblScope><biblScope unit="page" to="1298">1298</biblScope></imprint></monogr><idno type="istex">1B80B36CAB12DD09DC41EE0A12ECB4F41D9BF64E</idno><idno type="DOI">10.1002/mds.22563</idno><idno type="ArticleID">MDS22563</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2009</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>The Unified Dyskinesia Rating Scale (UDysRS) has been introduced as a comprehensive rating tool for the evaluation of dyskinesias in Parkinson's disease (PD). To enhance a uniform application, we developed a DVD‐based training program with instructions, patient examples, and a certification exercise. For training on the objective assessment of dyskinesia, seventy PD patients spanning the gamut of dyskinesias (none to severe) were videotaped during four tasks of daily living (speaking, drinking from a cup, putting on a coat, and walking). Dyskinesia severity in seven body parts was rated by 20 international movement disorder specialists using the UDysRS for impairment. Each task was also rated for disability. Inter‐rater reliability was assessed with generalized weighted kappa and intraclass correlation coefficients. For the teaching program, examples of each severity level and each body part were selected based on the criterion that they received a uniform rating (± 1 point) by at least 75% of the raters. For the certification exercise, four cases were selected to represent the four quartiles of overall objective UDysRS scores to reflect slight, mild, moderate, and severe dyskinesia. Each selection was based on the highest inter‐rater reliability score for that quartile (minimum kappa or intraclass correlation coefficient = 0.6). UDysRS ranges for certification were calculated based on the 95% confidence interval. The teaching program lasts 41 min, and the certification exercise requires 10 min (total 51 min). This training program, based on visual examples of dyskinesia and anchored in scores generated by movement disorder experts is aimed at increasing homogeneity of ratings among and within raters and centers. Large‐scale multicenter randomized clinical trials of dyskinesia treatment are strengthened by a uniform standard of scale application. © 2009 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Parkinson's disease</term></item><item><term>dyskinesia</term></item><item><term>rating scales</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Research Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2009-02-06">Received</change><change when="2009-03-03">Registration</change><change when="2009-07-15">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/1B80B36CAB12DD09DC41EE0A12ECB4F41D9BF64E/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="subtitle">Official Journal of the Movement Disorder Society</title><title type="short">Mov. 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To enhance a uniform application, we developed a DVD‐based training program with instructions, patient examples, and a certification exercise. For training on the objective assessment of dyskinesia, seventy PD patients spanning the gamut of dyskinesias (none to severe) were videotaped during four tasks of daily living (speaking, drinking from a cup, putting on a coat, and walking). Dyskinesia severity in seven body parts was rated by 20 international movement disorder specialists using the UDysRS for impairment. Each task was also rated for disability. Inter‐rater reliability was assessed with generalized weighted kappa and intraclass correlation coefficients. For the teaching program, examples of each severity level and each body part were selected based on the criterion that they received a uniform rating (± 1 point) by at least 75% of the raters. For the certification exercise, four cases were selected to represent the four quartiles of overall objective UDysRS scores to reflect slight, mild, moderate, and severe dyskinesia. Each selection was based on the highest inter‐rater reliability score for that quartile (minimum kappa or intraclass correlation coefficient = 0.6). UDysRS ranges for certification were calculated based on the 95% confidence interval. The teaching program lasts 41 min, and the certification exercise requires 10 min (total 51 min). This training program, based on visual examples of dyskinesia and anchored in scores generated by movement disorder experts is aimed at increasing homogeneity of ratings among and within raters and centers. Large‐scale multicenter randomized clinical trials of dyskinesia treatment are strengthened by a uniform standard of scale application. © 2009 Movement Disorder Society</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><p>Potential conflicts of interest: Dr. Goetz, Consulting and Advisory Board Membership in the past 3 years: Biogen, Boehringer‐Ingelheim, Cerogene, EMD Pharmaceuticals, Impax Pharmaceuticals, I3 Research, Juvantia Pharmaceuticals, Kiowa Pharmaceuticals, GlaxoSmith Kline, Merck KgaA, Merck and Co, Neurim Pharmaceuticals, Novartis Pharmaceuticals, Ovation Pharmaceuticals, Oxford Biomedica, Schering‐Plough, Solstice Neurosciences, Solvay Pharmaceuticals, Synergy/Intec, Teva Pharmaceuticals. He has received funding from NIH, Michael J. Fox Foundation, and directs the Rush Parkinson's Disease Research Center that receives support from the Parkinson's Disease Foundation. Dr. Stebbins, Consulting and Advisory Board Membership in the past three years: Boehringer‐Ingelheim, Novartis Pharmaceuticals. He has received funding from NIH, the Michael J. Fox Foundation, the Fragile X Foundation and the Kinetics Foundation. Dr. Nutt, Consulting and Advisory Board Positions: IMPAX Laboratories, Schering‐Plough Research, Xenoport, Inc. Research funding: NIH, MJFF, Kinetics Fdn, Ceregene, and National Parkinson Foundation. Dr. Nutt directs the Movement Disorder Program at OHSU and co‐directs the PADRECC at the Portland VA.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Teaching program for the Unified Dyskinesia Rating Scale</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Unified Dyskinesia Rating Scale</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Teaching program for the Unified Dyskinesia Rating Scale</title></titleInfo><name type="personal"><namePart type="given">Christopher G.</namePart><namePart type="family">Goetz</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</affiliation><description>Correspondence: Department of Neurological Sciences, Rush University Medical Center, Suite 755: 1725 West Harrison Street, Chicago, IL 60612</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">John G.</namePart><namePart type="family">Nutt</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Oregon Health Sciences University, Portland, Oregon, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Glenn T.</namePart><namePart type="family">Stebbins</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Teresa A.</namePart><namePart type="family">Chmura</namePart><namePart type="termsOfAddress">BS</namePart><affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2009-07-15</dateIssued><dateCaptured encoding="w3cdtf">2009-02-06</dateCaptured><dateValid encoding="w3cdtf">2009-03-03</dateValid><copyrightDate encoding="w3cdtf">2009</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="references">2</extent><extent unit="words">2213</extent></physicalDescription><abstract lang="en">The Unified Dyskinesia Rating Scale (UDysRS) has been introduced as a comprehensive rating tool for the evaluation of dyskinesias in Parkinson's disease (PD). To enhance a uniform application, we developed a DVD‐based training program with instructions, patient examples, and a certification exercise. For training on the objective assessment of dyskinesia, seventy PD patients spanning the gamut of dyskinesias (none to severe) were videotaped during four tasks of daily living (speaking, drinking from a cup, putting on a coat, and walking). Dyskinesia severity in seven body parts was rated by 20 international movement disorder specialists using the UDysRS for impairment. Each task was also rated for disability. Inter‐rater reliability was assessed with generalized weighted kappa and intraclass correlation coefficients. For the teaching program, examples of each severity level and each body part were selected based on the criterion that they received a uniform rating (± 1 point) by at least 75% of the raters. For the certification exercise, four cases were selected to represent the four quartiles of overall objective UDysRS scores to reflect slight, mild, moderate, and severe dyskinesia. Each selection was based on the highest inter‐rater reliability score for that quartile (minimum kappa or intraclass correlation coefficient = 0.6). UDysRS ranges for certification were calculated based on the 95% confidence interval. The teaching program lasts 41 min, and the certification exercise requires 10 min (total 51 min). This training program, based on visual examples of dyskinesia and anchored in scores generated by movement disorder experts is aimed at increasing homogeneity of ratings among and within raters and centers. Large‐scale multicenter randomized clinical trials of dyskinesia treatment are strengthened by a uniform standard of scale application. © 2009 Movement Disorder Society</abstract><note type="content">*Potential conflicts of interest: Dr. Goetz, Consulting and Advisory Board Membership in the past 3 years: Biogen, Boehringer‐Ingelheim, Cerogene, EMD Pharmaceuticals, Impax Pharmaceuticals, I3 Research, Juvantia Pharmaceuticals, Kiowa Pharmaceuticals, GlaxoSmith Kline, Merck KgaA, Merck and Co, Neurim Pharmaceuticals, Novartis Pharmaceuticals, Ovation Pharmaceuticals, Oxford Biomedica, Schering‐Plough, Solstice Neurosciences, Solvay Pharmaceuticals, Synergy/Intec, Teva Pharmaceuticals. He has received funding from NIH, Michael J. Fox Foundation, and directs the Rush Parkinson's Disease Research Center that receives support from the Parkinson's Disease Foundation. Dr. Stebbins, Consulting and Advisory Board Membership in the past three years: Boehringer‐Ingelheim, Novartis Pharmaceuticals. He has received funding from NIH, the Michael J. Fox Foundation, the Fragile X Foundation and the Kinetics Foundation. Dr. Nutt, Consulting and Advisory Board Positions: IMPAX Laboratories, Schering‐Plough Research, Xenoport, Inc. Research funding: NIH, MJFF, Kinetics Fdn, Ceregene, and National Parkinson Foundation. Dr. Nutt directs the Movement Disorder Program at OHSU and co‐directs the PADRECC at the Portland VA.</note><note type="funding">UDysRS</note><note type="funding">Michael J Fox Foundation</note><note type="funding">EMD/Merck KGaA Pharmaceuticals</note><note type="funding">Santhera Pharmaceuticals</note><note type="funding">i3 Research Inc.</note><note type="funding">Rush Movement Disorder Program is a Parkinson's Disease Foundation Research Center</note><note type="funding">OHSU Movement Disorder Program is a National Parkinson Disease Center of Excellence</note><subject lang="en"><genre>Keywords</genre><topic>Parkinson's disease</topic><topic>dyskinesia</topic><topic>rating scales</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><note type="content"> Additional Supporting Information may be found in the online version of this article.</note><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>24</number></detail><detail type="issue"><caption>no.</caption><number>9</number></detail><extent unit="pages"><start>1296</start><end>1298</end><total>3</total></extent></part></relatedItem><identifier type="istex">1B80B36CAB12DD09DC41EE0A12ECB4F41D9BF64E</identifier><identifier type="DOI">10.1002/mds.22563</identifier><identifier type="ArticleID">MDS22563</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2009 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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