Midbrain transcranial sonography in Korean patients with Parkinson's disease
Identifieur interne : 002087 ( Istex/Corpus ); précédent : 002086; suivant : 002088Midbrain transcranial sonography in Korean patients with Parkinson's disease
Auteurs : Ji Youn Kim ; Seong Tae Kim ; Seong Hee Jeon ; Won Yong LeeSource :
- Movement Disorders [ 0885-3185 ] ; 2007-10-15.
English descriptors
Abstract
Transcranial sonography (TCS) is potentially useful for the diagnosis of Parkinson's disease (PD). However, studies on TCS have so far been restricted to European populations. To investigate the efficacy of TCS in Korean PD patients and its correlation with the clinical features, we carried out midbrain TCS in 43 PD patients and 35 normal controls and evaluated the area of the substantia nigra (SN) hyperechogenicity and its ratio to the area of the whole midbrain. In 16 subjects (21%), TCS was unsuccessful due to insufficient acoustic temporal bone windows. The mean area of bilateral SN hyperechogenicity and its ratio to the midbrain area were greater in the PD patients than that in the controls (P < 0.01). In the PD patients, the area of SN hyperechogenicity and its ratio to the individual midbrain area were moderately correlated with the PD duration (r = 0.526 and 0.536, P = 0.01, respectively) but not with the age, UPDRS motor scores or H‐Y stage. There was no difference in the SN hyperechogenicity between the tremor‐dominant, akinetic‐rigid, and mixed‐type PD patients. In conclusion, midbrain TCS is an effective diagnostic tool for detecting PD in the Korean population. However, it does not reflect the severity or phenotypes of parkinsonism. © 2007 Movement Disorder Society
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DOI: 10.1002/mds.21628
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ISTEX:82866657589E761C6ED81FF1602F5B719CD4EE3DLe document en format XML
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However, studies on TCS have so far been restricted to European populations. To investigate the efficacy of TCS in Korean PD patients and its correlation with the clinical features, we carried out midbrain TCS in 43 PD patients and 35 normal controls and evaluated the area of the substantia nigra (SN) hyperechogenicity and its ratio to the area of the whole midbrain. In 16 subjects (21%), TCS was unsuccessful due to insufficient acoustic temporal bone windows. The mean area of bilateral SN hyperechogenicity and its ratio to the midbrain area were greater in the PD patients than that in the controls (P < 0.01). In the PD patients, the area of SN hyperechogenicity and its ratio to the individual midbrain area were moderately correlated with the PD duration (r = 0.526 and 0.536, P = 0.01, respectively) but not with the age, UPDRS motor scores or H‐Y stage. There was no difference in the SN hyperechogenicity between the tremor‐dominant, akinetic‐rigid, and mixed‐type PD patients. In conclusion, midbrain TCS is an effective diagnostic tool for detecting PD in the Korean population. However, it does not reflect the severity or phenotypes of parkinsonism. © 2007 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Ji Youn Kim MD</name><affiliations><json:string>Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea</json:string></affiliations></json:item><json:item><name>Seong Tae Kim MD, PhD</name><affiliations><json:string>Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea</json:string></affiliations></json:item><json:item><name>Seong Hee Jeon</name><affiliations><json:string>Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea</json:string></affiliations></json:item><json:item><name>Won Yong Lee MD, PhD</name><affiliations><json:string>Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>transcranial sonography</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>substantia nigra</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Korean</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Transcranial sonography (TCS) is potentially useful for the diagnosis of Parkinson's disease (PD). However, studies on TCS have so far been restricted to European populations. To investigate the efficacy of TCS in Korean PD patients and its correlation with the clinical features, we carried out midbrain TCS in 43 PD patients and 35 normal controls and evaluated the area of the substantia nigra (SN) hyperechogenicity and its ratio to the area of the whole midbrain. In 16 subjects (21%), TCS was unsuccessful due to insufficient acoustic temporal bone windows. The mean area of bilateral SN hyperechogenicity and its ratio to the midbrain area were greater in the PD patients than that in the controls (P > 0.01). In the PD patients, the area of SN hyperechogenicity and its ratio to the individual midbrain area were moderately correlated with the PD duration (r = 0.526 and 0.536, P = 0.01, respectively) but not with the age, UPDRS motor scores or H‐Y stage. There was no difference in the SN hyperechogenicity between the tremor‐dominant, akinetic‐rigid, and mixed‐type PD patients. In conclusion, midbrain TCS is an effective diagnostic tool for detecting PD in the Korean population. 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To investigate the efficacy of TCS in Korean PD patients and its correlation with the clinical features, we carried out midbrain TCS in 43 PD patients and 35 normal controls and evaluated the area of the substantia nigra (SN) hyperechogenicity and its ratio to the area of the whole midbrain. In 16 subjects (21%), TCS was unsuccessful due to insufficient acoustic temporal bone windows. The mean area of bilateral SN hyperechogenicity and its ratio to the midbrain area were greater in the PD patients than that in the controls (P < 0.01). In the PD patients, the area of SN hyperechogenicity and its ratio to the individual midbrain area were moderately correlated with the PD duration (r = 0.526 and 0.536, P = 0.01, respectively) but not with the age, UPDRS motor scores or H‐Y stage. There was no difference in the SN hyperechogenicity between the tremor‐dominant, akinetic‐rigid, and mixed‐type PD patients. In conclusion, midbrain TCS is an effective diagnostic tool for detecting PD in the Korean population. 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However, studies on TCS have so far been restricted to European populations. To investigate the efficacy of TCS in Korean PD patients and its correlation with the clinical features, we carried out midbrain TCS in 43 PD patients and 35 normal controls and evaluated the area of the substantia nigra (SN) hyperechogenicity and its ratio to the area of the whole midbrain. In 16 subjects (21%), TCS was unsuccessful due to insufficient acoustic temporal bone windows. The mean area of bilateral SN hyperechogenicity and its ratio to the midbrain area were greater in the PD patients than that in the controls (<i>P</i> < 0.01). In the PD patients, the area of SN hyperechogenicity and its ratio to the individual midbrain area were moderately correlated with the PD duration (r = 0.526 and 0.536, <i>P</i> = 0.01, respectively) but not with the age, UPDRS motor scores or H‐Y stage. There was no difference in the SN hyperechogenicity between the tremor‐dominant, akinetic‐rigid, and mixed‐type PD patients. In conclusion, midbrain TCS is an effective diagnostic tool for detecting PD in the Korean population. However, it does not reflect the severity or phenotypes of parkinsonism. © 2007 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Midbrain transcranial sonography in Korean patients with Parkinson's disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Midbrain TCS in Korean Patients with PD</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Midbrain transcranial sonography in Korean patients with Parkinson's disease</title></titleInfo><name type="personal"><namePart type="given">Ji Youn</namePart><namePart type="family">Kim</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Seong Tae</namePart><namePart type="family">Kim</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Seong Hee</namePart><namePart type="family">Jeon</namePart><affiliation>Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Won Yong</namePart><namePart type="family">Lee</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea</affiliation><description>Correspondence: Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50, Irwon‐Dong, Gangnam‐Gu, Seoul, 135‐710, Korea</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2007-10-15</dateIssued><dateCaptured encoding="w3cdtf">2007-02-27</dateCaptured><dateValid encoding="w3cdtf">2007-05-17</dateValid><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">2</extent><extent unit="tables">2</extent><extent unit="references">19</extent><extent unit="words">3115</extent></physicalDescription><abstract lang="en">Transcranial sonography (TCS) is potentially useful for the diagnosis of Parkinson's disease (PD). However, studies on TCS have so far been restricted to European populations. To investigate the efficacy of TCS in Korean PD patients and its correlation with the clinical features, we carried out midbrain TCS in 43 PD patients and 35 normal controls and evaluated the area of the substantia nigra (SN) hyperechogenicity and its ratio to the area of the whole midbrain. In 16 subjects (21%), TCS was unsuccessful due to insufficient acoustic temporal bone windows. The mean area of bilateral SN hyperechogenicity and its ratio to the midbrain area were greater in the PD patients than that in the controls (P < 0.01). In the PD patients, the area of SN hyperechogenicity and its ratio to the individual midbrain area were moderately correlated with the PD duration (r = 0.526 and 0.536, P = 0.01, respectively) but not with the age, UPDRS motor scores or H‐Y stage. There was no difference in the SN hyperechogenicity between the tremor‐dominant, akinetic‐rigid, and mixed‐type PD patients. In conclusion, midbrain TCS is an effective diagnostic tool for detecting PD in the Korean population. However, it does not reflect the severity or phenotypes of parkinsonism. © 2007 Movement Disorder Society</abstract><note type="funding">Samsung Medical Center Clinical Research Development Program - No. CRS106‐15‐1); </note><subject lang="en"><genre>Keywords</genre><topic>transcranial sonography</topic><topic>substantia nigra</topic><topic>Parkinson's disease</topic><topic>Korean</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><detail type="issue"><caption>no.</caption><number>13</number></detail><extent unit="pages"><start>1922</start><end>1926</end><total>5</total></extent></part></relatedItem><identifier type="istex">82866657589E761C6ED81FF1602F5B719CD4EE3D</identifier><identifier type="DOI">10.1002/mds.21628</identifier><identifier type="ArticleID">MDS21628</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2007 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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