Analysis of blink rate in patients with blepharospasm
Identifieur interne : 001D75 ( Istex/Corpus ); précédent : 001D74; suivant : 001D76Analysis of blink rate in patients with blepharospasm
Auteurs : Anna Rita Bentivoglio ; Antonio Daniele ; Alberto Albanese ; Pietro Attilio Tonali ; Alfonso FasanoSource :
- Movement Disorders [ 0885-3185 ] ; 2006-08.
English descriptors
- KwdEn :
Abstract
The blink rate (BR) during rest, conversation, and reading was assessed in 50 patients with blepharospasm (BS) and in 150 healthy subjects. BR at rest and during conversation was higher in patients with BS. Moreover, 76% of patients had BR higher at rest than during conversation, whereas in 74% of controls, BR was higher during conversation than at rest. The sensitivity and specificity of two parameters (value of BR at rest and pattern rest‐BR higher than conversation‐BR) in discriminating patients and controls were computed. The best fit was obtained with a rest‐BR above 27 blinks per minute. When the two parameters were combined (rest‐BR above 27 blinks per minute together with the pattern rest‐BR higher than conversation‐BR), we obtained a 92.3% sensitivity and a 82.0% specificity in discriminating between BS patients and controls. These findings indicate that specific features of BR can be associated with BS, suggesting that the analysis of BR might be helpful for the diagnosis of BS in early stages. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.20889
Links to Exploration step
ISTEX:A3FD52B28025B5D4E088C8984D773C088C52C277Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Analysis of blink rate in patients with blepharospasm</title><author><name sortKey="Bentivoglio, Anna Rita" sort="Bentivoglio, Anna Rita" uniqKey="Bentivoglio A" first="Anna Rita" last="Bentivoglio">Anna Rita Bentivoglio</name><affiliation><mods:affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</mods:affiliation></affiliation></author><author><name sortKey="Daniele, Antonio" sort="Daniele, Antonio" uniqKey="Daniele A" first="Antonio" last="Daniele">Antonio Daniele</name><affiliation><mods:affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</mods:affiliation></affiliation></author><author><name sortKey="Albanese, Alberto" sort="Albanese, Alberto" uniqKey="Albanese A" first="Alberto" last="Albanese">Alberto Albanese</name><affiliation><mods:affiliation>Istituto Nazionale Neurologico Carlo Besta, Milano, Italy</mods:affiliation></affiliation></author><author><name sortKey="Tonali, Pietro Attilio" sort="Tonali, Pietro Attilio" uniqKey="Tonali P" first="Pietro Attilio" last="Tonali">Pietro Attilio Tonali</name><affiliation><mods:affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</mods:affiliation></affiliation><affiliation><mods:affiliation>Fondazione Don Carlo Gnocchi, Milano, Italy</mods:affiliation></affiliation></author><author><name sortKey="Fasano, Alfonso" sort="Fasano, Alfonso" uniqKey="Fasano A" first="Alfonso" last="Fasano">Alfonso Fasano</name><affiliation><mods:affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:A3FD52B28025B5D4E088C8984D773C088C52C277</idno><date when="2006" year="2006">2006</date><idno type="doi">10.1002/mds.20889</idno><idno type="url">https://api.istex.fr/document/A3FD52B28025B5D4E088C8984D773C088C52C277/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001D75</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Analysis of blink rate in patients with blepharospasm</title><author><name sortKey="Bentivoglio, Anna Rita" sort="Bentivoglio, Anna Rita" uniqKey="Bentivoglio A" first="Anna Rita" last="Bentivoglio">Anna Rita Bentivoglio</name><affiliation><mods:affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</mods:affiliation></affiliation></author><author><name sortKey="Daniele, Antonio" sort="Daniele, Antonio" uniqKey="Daniele A" first="Antonio" last="Daniele">Antonio Daniele</name><affiliation><mods:affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</mods:affiliation></affiliation></author><author><name sortKey="Albanese, Alberto" sort="Albanese, Alberto" uniqKey="Albanese A" first="Alberto" last="Albanese">Alberto Albanese</name><affiliation><mods:affiliation>Istituto Nazionale Neurologico Carlo Besta, Milano, Italy</mods:affiliation></affiliation></author><author><name sortKey="Tonali, Pietro Attilio" sort="Tonali, Pietro Attilio" uniqKey="Tonali P" first="Pietro Attilio" last="Tonali">Pietro Attilio Tonali</name><affiliation><mods:affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</mods:affiliation></affiliation><affiliation><mods:affiliation>Fondazione Don Carlo Gnocchi, Milano, Italy</mods:affiliation></affiliation></author><author><name sortKey="Fasano, Alfonso" sort="Fasano, Alfonso" uniqKey="Fasano A" first="Alfonso" last="Fasano">Alfonso Fasano</name><affiliation><mods:affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2006-08">2006-08</date><biblScope unit="vol">21</biblScope><biblScope unit="issue">8</biblScope><biblScope unit="page" from="1225">1225</biblScope><biblScope unit="page" to="1229">1229</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">A3FD52B28025B5D4E088C8984D773C088C52C277</idno><idno type="DOI">10.1002/mds.20889</idno><idno type="ArticleID">MDS20889</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>blepharospasm</term><term>blinking</term><term>dystonia</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The blink rate (BR) during rest, conversation, and reading was assessed in 50 patients with blepharospasm (BS) and in 150 healthy subjects. BR at rest and during conversation was higher in patients with BS. Moreover, 76% of patients had BR higher at rest than during conversation, whereas in 74% of controls, BR was higher during conversation than at rest. The sensitivity and specificity of two parameters (value of BR at rest and pattern rest‐BR higher than conversation‐BR) in discriminating patients and controls were computed. The best fit was obtained with a rest‐BR above 27 blinks per minute. When the two parameters were combined (rest‐BR above 27 blinks per minute together with the pattern rest‐BR higher than conversation‐BR), we obtained a 92.3% sensitivity and a 82.0% specificity in discriminating between BS patients and controls. These findings indicate that specific features of BR can be associated with BS, suggesting that the analysis of BR might be helpful for the diagnosis of BS in early stages. © 2006 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Anna Rita Bentivoglio MD, PhD</name><affiliations><json:string>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</json:string></affiliations></json:item><json:item><name>Antonio Daniele MD, PhD</name><affiliations><json:string>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</json:string></affiliations></json:item><json:item><name>Alberto Albanese MD</name><affiliations><json:string>Istituto Nazionale Neurologico Carlo Besta, Milano, Italy</json:string></affiliations></json:item><json:item><name>Pietro Attilio Tonali MD</name><affiliations><json:string>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</json:string><json:string>Fondazione Don Carlo Gnocchi, Milano, Italy</json:string></affiliations></json:item><json:item><name>Alfonso Fasano MD</name><affiliations><json:string>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>blepharospasm</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>blinking</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>dystonia</value></json:item></subject><language><json:string>eng</json:string></language><abstract>The blink rate (BR) during rest, conversation, and reading was assessed in 50 patients with blepharospasm (BS) and in 150 healthy subjects. BR at rest and during conversation was higher in patients with BS. Moreover, 76% of patients had BR higher at rest than during conversation, whereas in 74% of controls, BR was higher during conversation than at rest. The sensitivity and specificity of two parameters (value of BR at rest and pattern rest‐BR higher than conversation‐BR) in discriminating patients and controls were computed. The best fit was obtained with a rest‐BR above 27 blinks per minute. When the two parameters were combined (rest‐BR above 27 blinks per minute together with the pattern rest‐BR higher than conversation‐BR), we obtained a 92.3% sensitivity and a 82.0% specificity in discriminating between BS patients and controls. These findings indicate that specific features of BR can be associated with BS, suggesting that the analysis of BR might be helpful for the diagnosis of BS in early stages. © 2006 Movement Disorder Society</abstract><qualityIndicators><score>5.499</score><pdfVersion>1.3</pdfVersion><pdfPageSize>594 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>1052</abstractCharCount><pdfWordCount>3483</pdfWordCount><pdfCharCount>22156</pdfCharCount><pdfPageCount>5</pdfPageCount><abstractWordCount>168</abstractWordCount></qualityIndicators><title>Analysis of blink rate in patients with blepharospasm</title><genre><json:string>Serial article</json:string></genre><host><volume>21</volume><pages><total>4</total><last>1229</last><first>1225</first></pages><issn><json:string>0885-3185</json:string></issn><issue>8</issue><subject><json:item><value>Brief Report</value></json:item></subject><genre></genre><language><json:string>unknown</json:string></language><title>Movement Disorders</title><doi><json:string>10.1002/(ISSN)1531-8257</json:string></doi></host><publicationDate>2006</publicationDate><copyrightDate>2006</copyrightDate><doi><json:string>10.1002/mds.20889</json:string></doi><id>A3FD52B28025B5D4E088C8984D773C088C52C277</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/A3FD52B28025B5D4E088C8984D773C088C52C277/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/A3FD52B28025B5D4E088C8984D773C088C52C277/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/A3FD52B28025B5D4E088C8984D773C088C52C277/fulltext/tei"><teiHeader type="text"><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Analysis of blink rate in patients with blepharospasm</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><p>Wiley Subscription Services, Inc., A Wiley Company</p></availability><date>2006</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Analysis of blink rate in patients with blepharospasm</title><author><persName><forename type="first">Anna Rita</forename><surname>Bentivoglio</surname><roleName type="degree">MD, PhD</roleName></persName><note type="correspondence"><p>Correspondence: Istituto di Neurologia Università Cattolica del Sacro Cuore Largo Agostino Gemelli, 8 00168 Roma, Italy</p></note><affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</affiliation></author><author><persName><forename type="first">Antonio</forename><surname>Daniele</surname><roleName type="degree">MD, PhD</roleName></persName><affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</affiliation></author><author><persName><forename type="first">Alberto</forename><surname>Albanese</surname><roleName type="degree">MD</roleName></persName><affiliation>Istituto Nazionale Neurologico Carlo Besta, Milano, Italy</affiliation></author><author><persName><forename type="first">Pietro Attilio</forename><surname>Tonali</surname><roleName type="degree">MD</roleName></persName><affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</affiliation><affiliation>Fondazione Don Carlo Gnocchi, Milano, Italy</affiliation></author><author><persName><forename type="first">Alfonso</forename><surname>Fasano</surname><roleName type="degree">MD</roleName></persName><affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</affiliation></author></analytic><monogr><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2006-08"></date><biblScope unit="vol">21</biblScope><biblScope unit="issue">8</biblScope><biblScope unit="page" from="1225">1225</biblScope><biblScope unit="page" to="1229">1229</biblScope></imprint></monogr><idno type="istex">A3FD52B28025B5D4E088C8984D773C088C52C277</idno><idno type="DOI">10.1002/mds.20889</idno><idno type="ArticleID">MDS20889</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2006</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>The blink rate (BR) during rest, conversation, and reading was assessed in 50 patients with blepharospasm (BS) and in 150 healthy subjects. BR at rest and during conversation was higher in patients with BS. Moreover, 76% of patients had BR higher at rest than during conversation, whereas in 74% of controls, BR was higher during conversation than at rest. The sensitivity and specificity of two parameters (value of BR at rest and pattern rest‐BR higher than conversation‐BR) in discriminating patients and controls were computed. The best fit was obtained with a rest‐BR above 27 blinks per minute. When the two parameters were combined (rest‐BR above 27 blinks per minute together with the pattern rest‐BR higher than conversation‐BR), we obtained a 92.3% sensitivity and a 82.0% specificity in discriminating between BS patients and controls. These findings indicate that specific features of BR can be associated with BS, suggesting that the analysis of BR might be helpful for the diagnosis of BS in early stages. © 2006 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>blepharospasm</term></item><item><term>blinking</term></item><item><term>dystonia</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Brief Report</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2005-03-22">Received</change><change when="2005-11-13">Registration</change><change when="2006-08">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/A3FD52B28025B5D4E088C8984D773C088C52C277/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="subtitle">Official Journal of the Movement Disorder Society</title><title type="short">Mov. Disord.</title></titleGroup></publicationMeta><publicationMeta level="part" position="80"><doi origin="wiley" registered="yes">10.1002/mds.v21:8</doi><numberingGroup><numbering type="journalVolume" number="21">21</numbering><numbering type="journalIssue">8</numbering></numberingGroup><coverDate startDate="2006-08">August 2006</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="300" status="forIssue"><doi origin="wiley" registered="yes">10.1002/mds.20889</doi><idGroup><id type="unit" value="MDS20889"></id></idGroup><countGroup><count type="pageTotal" number="4"></count></countGroup><titleGroup><title type="articleCategory">Brief Report</title><title type="tocHeading1">Brief Reports</title></titleGroup><copyright ownership="thirdParty">Copyright © 2006 Movement Disorder Society</copyright><eventGroup><event type="manuscriptReceived" date="2005-03-22"></event><event type="manuscriptRevised" date="2005-11-05"></event><event type="manuscriptAccepted" date="2005-11-13"></event><event type="publishedOnlineEarlyUnpaginated" date="2006-04-18"></event><event type="firstOnline" date="2006-04-18"></event><event type="publishedOnlineFinalForm" date="2006-08-22"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.2 mode:FullText source:FullText result:FullText" date="2010-03-09"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-02"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-31"></event></eventGroup><numberingGroup><numbering type="pageFirst">1225</numbering><numbering type="pageLast">1229</numbering></numberingGroup><correspondenceTo>Istituto di Neurologia Università Cattolica del Sacro Cuore Largo Agostino Gemelli, 8 00168 Roma, Italy</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:MDS.MDS20889.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="1"></count><count type="tableTotal" number="1"></count><count type="referenceTotal" number="15"></count><count type="wordTotal" number="2660"></count></countGroup><titleGroup><title type="main" xml:lang="en">Analysis of blink rate in patients with blepharospasm</title><title type="short" xml:lang="en">Blink Rate in Blepharospasm</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Anna Rita</givenNames><familyName>Bentivoglio</familyName><degrees>MD, PhD</degrees></personName><contactDetails><email>annarita.bentivoglio@rm.unicatt.it</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Antonio</givenNames><familyName>Daniele</familyName><degrees>MD, PhD</degrees></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Alberto</givenNames><familyName>Albanese</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af1 #af3"><personName><givenNames>Pietro Attilio</givenNames><familyName>Tonali</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Alfonso</givenNames><familyName>Fasano</familyName><degrees>MD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="IT" type="organization"><unparsedAffiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="IT" type="organization"><unparsedAffiliation>Istituto Nazionale Neurologico Carlo Besta, Milano, Italy</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="IT" type="organization"><unparsedAffiliation>Fondazione Don Carlo Gnocchi, Milano, Italy</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">blepharospasm</keyword><keyword xml:id="kwd2">blinking</keyword><keyword xml:id="kwd3">dystonia</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>The blink rate (BR) during rest, conversation, and reading was assessed in 50 patients with blepharospasm (BS) and in 150 healthy subjects. BR at rest and during conversation was higher in patients with BS. Moreover, 76% of patients had BR higher at rest than during conversation, whereas in 74% of controls, BR was higher during conversation than at rest. The sensitivity and specificity of two parameters (value of BR at rest and pattern <i>rest‐BR higher than conversation‐BR</i>) in discriminating patients and controls were computed. The best fit was obtained with a rest‐BR above 27 blinks per minute. When the two parameters were combined (rest‐BR above 27 blinks per minute together with the pattern <i>rest‐BR higher than conversation‐BR</i>), we obtained a 92.3% sensitivity and a 82.0% specificity in discriminating between BS patients and controls. These findings indicate that specific features of BR can be associated with BS, suggesting that the analysis of BR might be helpful for the diagnosis of BS in early stages. © 2006 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Analysis of blink rate in patients with blepharospasm</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Blink Rate in Blepharospasm</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Analysis of blink rate in patients with blepharospasm</title></titleInfo><name type="personal"><namePart type="given">Anna Rita</namePart><namePart type="family">Bentivoglio</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</affiliation><description>Correspondence: Istituto di Neurologia Università Cattolica del Sacro Cuore Largo Agostino Gemelli, 8 00168 Roma, Italy</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Antonio</namePart><namePart type="family">Daniele</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Alberto</namePart><namePart type="family">Albanese</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Istituto Nazionale Neurologico Carlo Besta, Milano, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Pietro Attilio</namePart><namePart type="family">Tonali</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</affiliation><affiliation>Fondazione Don Carlo Gnocchi, Milano, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Alfonso</namePart><namePart type="family">Fasano</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2006-08</dateIssued><dateCaptured encoding="w3cdtf">2005-03-22</dateCaptured><dateValid encoding="w3cdtf">2005-11-13</dateValid><copyrightDate encoding="w3cdtf">2006</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="tables">1</extent><extent unit="references">15</extent><extent unit="words">2660</extent></physicalDescription><abstract lang="en">The blink rate (BR) during rest, conversation, and reading was assessed in 50 patients with blepharospasm (BS) and in 150 healthy subjects. BR at rest and during conversation was higher in patients with BS. Moreover, 76% of patients had BR higher at rest than during conversation, whereas in 74% of controls, BR was higher during conversation than at rest. The sensitivity and specificity of two parameters (value of BR at rest and pattern rest‐BR higher than conversation‐BR) in discriminating patients and controls were computed. The best fit was obtained with a rest‐BR above 27 blinks per minute. When the two parameters were combined (rest‐BR above 27 blinks per minute together with the pattern rest‐BR higher than conversation‐BR), we obtained a 92.3% sensitivity and a 82.0% specificity in discriminating between BS patients and controls. These findings indicate that specific features of BR can be associated with BS, suggesting that the analysis of BR might be helpful for the diagnosis of BS in early stages. © 2006 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>blepharospasm</topic><topic>blinking</topic><topic>dystonia</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>21</number></detail><detail type="issue"><caption>no.</caption><number>8</number></detail><extent unit="pages"><start>1225</start><end>1229</end><total>4</total></extent></part></relatedItem><identifier type="istex">A3FD52B28025B5D4E088C8984D773C088C52C277</identifier><identifier type="DOI">10.1002/mds.20889</identifier><identifier type="ArticleID">MDS20889</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2006 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001D75 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 001D75 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:A3FD52B28025B5D4E088C8984D773C088C52C277
|texte= Analysis of blink rate in patients with blepharospasm
}}
| This area was generated with Dilib version V0.6.23. |  |