A defect of kinesthesia in Parkinson's disease
Identifieur interne : 001A43 ( Istex/Corpus ); précédent : 001A42; suivant : 001A44A defect of kinesthesia in Parkinson's disease
Auteurs : Klockgether ; Maike Borutta ; Herbert Rapp ; Sybille Spieker ; Johannes DichgansSource :
- Movement Disorders [ 0885-3185 ] ; 1995-07.
English descriptors
Abstract
Patients suffering from Parkinson's disease (PD) are more dependent on visual feedback during movement than are normals. Studying two‐dimensional pointing movements, we recently found that PD patients undershoot targets when vision of their own moving hand is occluded but not when complete vision is provided or when the target is extinguished immediately before movement onset. In the absence of vision, information about position of the moving hand may originate from peripheral kinesthetic feedback and from corollary discharges derved from the efferent motor signal. To find out which of both mechanisms–kinesthetic feedback or corollary discharge–is defective in PD, we compared active movements with imposed movements in which the hand is passively moved by the experimenter, whereas vision of the hand was occluded under either condition. In agreement with our earlier findings, slow, active pointing movements of PD patients were hypometric. In addition, PD patients terminated passively imposed movements of comparable speed earlier than did normals, with the consequence that imposed movements were equally hypometric. Our results make it unlikely that disturbed corollary discharge is responsible for hypometria under nonvisual conditions. Instead, the data suggest that PD patients have a defect of kinesthesia in slowly executed movements.
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DOI: 10.1002/mds.870100410
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ISTEX:0752CB14867A0ABF057BDA14BF87648AA7F18BB9Le document en format XML
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="1995-07">1995-07</date><biblScope unit="vol">10</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="460">460</biblScope><biblScope unit="page" to="465">465</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">0752CB14867A0ABF057BDA14BF87648AA7F18BB9</idno><idno type="DOI">10.1002/mds.870100410</idno><idno type="ArticleID">MDS870100410</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Corollary discharges</term><term>Kinesthesia</term><term>Parkinson's disease</term><term>Visual feedback</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Patients suffering from Parkinson's disease (PD) are more dependent on visual feedback during movement than are normals. Studying two‐dimensional pointing movements, we recently found that PD patients undershoot targets when vision of their own moving hand is occluded but not when complete vision is provided or when the target is extinguished immediately before movement onset. In the absence of vision, information about position of the moving hand may originate from peripheral kinesthetic feedback and from corollary discharges derved from the efferent motor signal. To find out which of both mechanisms–kinesthetic feedback or corollary discharge–is defective in PD, we compared active movements with imposed movements in which the hand is passively moved by the experimenter, whereas vision of the hand was occluded under either condition. In agreement with our earlier findings, slow, active pointing movements of PD patients were hypometric. In addition, PD patients terminated passively imposed movements of comparable speed earlier than did normals, with the consequence that imposed movements were equally hypometric. Our results make it unlikely that disturbed corollary discharge is responsible for hypometria under nonvisual conditions. Instead, the data suggest that PD patients have a defect of kinesthesia in slowly executed movements.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Dr. Klockgether</name><affiliations><json:string>Department of Neurology, University of Tübingen, Tübingen, Germany</json:string></affiliations></json:item><json:item><name>Maike Borutta</name><affiliations><json:string>Department of Neurology, University of Tübingen, Tübingen, Germany</json:string></affiliations></json:item><json:item><name>Herbert Rapp</name><affiliations><json:string>Department of Neurology, University of Tübingen, Tübingen, Germany</json:string></affiliations></json:item><json:item><name>Sybille Spieker</name><affiliations><json:string>Department of Neurology, University of Tübingen, Tübingen, Germany</json:string></affiliations></json:item><json:item><name>Johannes Dichgans</name><affiliations><json:string>Department of Neurology, University of Tübingen, Tübingen, Germany</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Kinesthesia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Visual feedback</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Corollary discharges</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Patients suffering from Parkinson's disease (PD) are more dependent on visual feedback during movement than are normals. Studying two‐dimensional pointing movements, we recently found that PD patients undershoot targets when vision of their own moving hand is occluded but not when complete vision is provided or when the target is extinguished immediately before movement onset. In the absence of vision, information about position of the moving hand may originate from peripheral kinesthetic feedback and from corollary discharges derved from the efferent motor signal. To find out which of both mechanisms–kinesthetic feedback or corollary discharge–is defective in PD, we compared active movements with imposed movements in which the hand is passively moved by the experimenter, whereas vision of the hand was occluded under either condition. In agreement with our earlier findings, slow, active pointing movements of PD patients were hypometric. In addition, PD patients terminated passively imposed movements of comparable speed earlier than did normals, with the consequence that imposed movements were equally hypometric. Our results make it unlikely that disturbed corollary discharge is responsible for hypometria under nonvisual conditions. 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Studying two‐dimensional pointing movements, we recently found that PD patients undershoot targets when vision of their own moving hand is occluded but not when complete vision is provided or when the target is extinguished immediately before movement onset. In the absence of vision, information about position of the moving hand may originate from peripheral kinesthetic feedback and from corollary discharges derved from the efferent motor signal. To find out which of both mechanisms–kinesthetic feedback or corollary discharge–is defective in PD, we compared active movements with imposed movements in which the hand is passively moved by the experimenter, whereas vision of the hand was occluded under either condition. In agreement with our earlier findings, slow, active pointing movements of PD patients were hypometric. In addition, PD patients terminated passively imposed movements of comparable speed earlier than did normals, with the consequence that imposed movements were equally hypometric. Our results make it unlikely that disturbed corollary discharge is responsible for hypometria under nonvisual conditions. 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Studying two‐dimensional pointing movements, we recently found that PD patients undershoot targets when vision of their own moving hand is occluded but not when complete vision is provided or when the target is extinguished immediately before movement onset. In the absence of vision, information about position of the moving hand may originate from peripheral kinesthetic feedback and from corollary discharges derved from the efferent motor signal. To find out which of both mechanisms–kinesthetic feedback or corollary discharge–is defective in PD, we compared active movements with imposed movements in which the hand is passively moved by the experimenter, whereas vision of the hand was occluded under either condition. In agreement with our earlier findings, slow, active pointing movements of PD patients were hypometric. In addition, PD patients terminated passively imposed movements of comparable speed earlier than did normals, with the consequence that imposed movements were equally hypometric. Our results make it unlikely that disturbed corollary discharge is responsible for hypometria under nonvisual conditions. Instead, the data suggest that PD patients have a defect of kinesthesia in slowly executed movements.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>A defect of kinesthesia in Parkinson's disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>KINESTHESIA IN PD</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>A defect of kinesthesia in Parkinson's disease</title></titleInfo><name type="personal"><namePart type="termsOfAddress">Dr.</namePart><namePart type="family">Klockgether</namePart><affiliation>Department of Neurology, University of Tübingen, Tübingen, Germany</affiliation><description>Correspondence: Depatment of Neurology, University of Tübingen, Hoppe‐Seyler‐Str. 3, D‐72076 Tübingen, Germany</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Maike</namePart><namePart type="family">Borutta</namePart><affiliation>Department of Neurology, University of Tübingen, Tübingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Herbert</namePart><namePart type="family">Rapp</namePart><affiliation>Department of Neurology, University of Tübingen, Tübingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Sybille</namePart><namePart type="family">Spieker</namePart><affiliation>Department of Neurology, University of Tübingen, Tübingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Johannes</namePart><namePart type="family">Dichgans</namePart><affiliation>Department of Neurology, University of Tübingen, Tübingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">1995-07</dateIssued><dateValid encoding="w3cdtf">1994-11-30</dateValid><copyrightDate encoding="w3cdtf">1995</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="references">20</extent></physicalDescription><abstract lang="en">Patients suffering from Parkinson's disease (PD) are more dependent on visual feedback during movement than are normals. Studying two‐dimensional pointing movements, we recently found that PD patients undershoot targets when vision of their own moving hand is occluded but not when complete vision is provided or when the target is extinguished immediately before movement onset. In the absence of vision, information about position of the moving hand may originate from peripheral kinesthetic feedback and from corollary discharges derved from the efferent motor signal. To find out which of both mechanisms–kinesthetic feedback or corollary discharge–is defective in PD, we compared active movements with imposed movements in which the hand is passively moved by the experimenter, whereas vision of the hand was occluded under either condition. In agreement with our earlier findings, slow, active pointing movements of PD patients were hypometric. In addition, PD patients terminated passively imposed movements of comparable speed earlier than did normals, with the consequence that imposed movements were equally hypometric. Our results make it unlikely that disturbed corollary discharge is responsible for hypometria under nonvisual conditions. Instead, the data suggest that PD patients have a defect of kinesthesia in slowly executed movements.</abstract><subject lang="en"><genre>Keywords</genre><topic>Kinesthesia</topic><topic>Parkinson's disease</topic><topic>Visual feedback</topic><topic>Corollary discharges</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. 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