Time of loss of employment in Parkinson's disease
Identifieur interne : 001A35 ( Istex/Corpus ); précédent : 001A34; suivant : 001A36Time of loss of employment in Parkinson's disease
Auteurs : Anette Schrag ; Pauline BanksSource :
- Movement Disorders [ 0885-3185 ] ; 2006-11.
English descriptors
- KwdEn :
Abstract
We examined time to loss of employment in two U.K.‐based studies of 151 and 308 patients with Parkinson's disease (PD) with onset age before 65 years. Fifty‐two percent and 57% of patients had retired early due to PD, 18% and 5% of patients were unemployed, and 8% and 11% were part‐time–employed. Mean age of retirement was 55.8 years compared to an average retirement age of 62 years in the U.K. population. Mean time to loss of employment was 4.9 years, ranging from a mean of 6.7 years in those with onset before age 45 to 1.7 years in those with onset after age 56, but the range was large (0–17 years). After censoring for those still working and those retiring at a normal retirement age, survival analysis revealed that 46% had stopped working after a disease duration of 5 years and 82% after 10 years with a median survival to loss of employment of 6.0 (95% CI: 5.4–6.6) years. Age of onset correlated negatively with time to loss of employment (r = −0.6; P < 0.001). There were no differences between sexes, rural vs. urban living, types of work, those living alone or with a partner, and those with and without children in their household. We conclude that Parkinson's disease leads to loss of employment on average within less than 10 years of disease onset. However, the variability of time to loss of employment is large, indicating that other factors than onset age and disease duration influence loss of patients' employment. © 2006 Movement Disorder Society
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DOI: 10.1002/mds.21030
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Fifty‐two percent and 57% of patients had retired early due to PD, 18% and 5% of patients were unemployed, and 8% and 11% were part‐time–employed. Mean age of retirement was 55.8 years compared to an average retirement age of 62 years in the U.K. population. Mean time to loss of employment was 4.9 years, ranging from a mean of 6.7 years in those with onset before age 45 to 1.7 years in those with onset after age 56, but the range was large (0–17 years). After censoring for those still working and those retiring at a normal retirement age, survival analysis revealed that 46% had stopped working after a disease duration of 5 years and 82% after 10 years with a median survival to loss of employment of 6.0 (95% CI: 5.4–6.6) years. Age of onset correlated negatively with time to loss of employment (r = −0.6; P < 0.001). There were no differences between sexes, rural vs. urban living, types of work, those living alone or with a partner, and those with and without children in their household. We conclude that Parkinson's disease leads to loss of employment on average within less than 10 years of disease onset. However, the variability of time to loss of employment is large, indicating that other factors than onset age and disease duration influence loss of patients' employment. © 2006 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Anette Schrag MD, PhD</name><affiliations><json:string>Royal Free and University College Medical School, University College London, London, United Kingdom</json:string><json:string>Institute of Neurology, University College London, London, United Kingdom</json:string></affiliations></json:item><json:item><name>Pauline Banks PhD</name><affiliations><json:string>Strathclyde Centre for Disability Research, University of Glasgow, Glasgow, United Kingdom</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>loss of employment</value></json:item></subject><language><json:string>eng</json:string></language><abstract>We examined time to loss of employment in two U.K.‐based studies of 151 and 308 patients with Parkinson's disease (PD) with onset age before 65 years. 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There were no differences between sexes, rural vs. urban living, types of work, those living alone or with a partner, and those with and without children in their household. We conclude that Parkinson's disease leads to loss of employment on average within less than 10 years of disease onset. 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Fifty‐two percent and 57% of patients had retired early due to PD, 18% and 5% of patients were unemployed, and 8% and 11% were part‐time–employed. Mean age of retirement was 55.8 years compared to an average retirement age of 62 years in the U.K. population. Mean time to loss of employment was 4.9 years, ranging from a mean of 6.7 years in those with onset before age 45 to 1.7 years in those with onset after age 56, but the range was large (0–17 years). After censoring for those still working and those retiring at a normal retirement age, survival analysis revealed that 46% had stopped working after a disease duration of 5 years and 82% after 10 years with a median survival to loss of employment of 6.0 (95% CI: 5.4–6.6) years. Age of onset correlated negatively with time to loss of employment (r = −0.6; P < 0.001). There were no differences between sexes, rural vs. urban living, types of work, those living alone or with a partner, and those with and without children in their household. We conclude that Parkinson's disease leads to loss of employment on average within less than 10 years of disease onset. 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Fifty‐two percent and 57% of patients had retired early due to PD, 18% and 5% of patients were unemployed, and 8% and 11% were part‐time–employed. Mean age of retirement was 55.8 years compared to an average retirement age of 62 years in the U.K. population. Mean time to loss of employment was 4.9 years, ranging from a mean of 6.7 years in those with onset before age 45 to 1.7 years in those with onset after age 56, but the range was large (0–17 years). After censoring for those still working and those retiring at a normal retirement age, survival analysis revealed that 46% had stopped working after a disease duration of 5 years and 82% after 10 years with a median survival to loss of employment of 6.0 (95% CI: 5.4–6.6) years. Age of onset correlated negatively with time to loss of employment (r = −0.6; <i>P</i> < 0.001). There were no differences between sexes, rural vs. urban living, types of work, those living alone or with a partner, and those with and without children in their household. We conclude that Parkinson's disease leads to loss of employment on average within less than 10 years of disease onset. However, the variability of time to loss of employment is large, indicating that other factors than onset age and disease duration influence loss of patients' employment. © 2006 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Time of loss of employment in Parkinson's disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Loss of Employment in Parkinson's Disease</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Time of loss of employment in Parkinson's disease</title></titleInfo><name type="personal"><namePart type="given">Anette</namePart><namePart type="family">Schrag</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Royal Free and University College Medical School, University College London, London, United Kingdom</affiliation><affiliation>Institute of Neurology, University College London, London, United Kingdom</affiliation><description>Correspondence: Royal Free and University College Medical School, University College London, NW3 2PF, London, United Kingdom</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Pauline</namePart><namePart type="family">Banks</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Strathclyde Centre for Disability Research, University of Glasgow, Glasgow, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2006-11</dateIssued><dateCaptured encoding="w3cdtf">2005-03-20</dateCaptured><dateValid encoding="w3cdtf">2005-11-03</dateValid><copyrightDate encoding="w3cdtf">2006</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">3</extent><extent unit="tables">3</extent><extent unit="references">11</extent><extent unit="words">3243</extent></physicalDescription><abstract lang="en">We examined time to loss of employment in two U.K.‐based studies of 151 and 308 patients with Parkinson's disease (PD) with onset age before 65 years. Fifty‐two percent and 57% of patients had retired early due to PD, 18% and 5% of patients were unemployed, and 8% and 11% were part‐time–employed. Mean age of retirement was 55.8 years compared to an average retirement age of 62 years in the U.K. population. Mean time to loss of employment was 4.9 years, ranging from a mean of 6.7 years in those with onset before age 45 to 1.7 years in those with onset after age 56, but the range was large (0–17 years). After censoring for those still working and those retiring at a normal retirement age, survival analysis revealed that 46% had stopped working after a disease duration of 5 years and 82% after 10 years with a median survival to loss of employment of 6.0 (95% CI: 5.4–6.6) years. Age of onset correlated negatively with time to loss of employment (r = −0.6; P < 0.001). There were no differences between sexes, rural vs. urban living, types of work, those living alone or with a partner, and those with and without children in their household. We conclude that Parkinson's disease leads to loss of employment on average within less than 10 years of disease onset. However, the variability of time to loss of employment is large, indicating that other factors than onset age and disease duration influence loss of patients' employment. © 2006 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>Parkinson's disease</topic><topic>loss of employment</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. 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