Parkinsonism after glycine‐derivate exposure
Identifieur interne : 001995 ( Istex/Corpus ); précédent : 001994; suivant : 001996Parkinsonism after glycine‐derivate exposure
Auteurs : Egberto R. Barbosa ; Maria D. Leiros Da Costa ; Luiz A. Bacheschi ; Milberto Scaff ; Claudia C. LeiteSource :
- Movement Disorders [ 0885-3185 ] ; 2001-05.
Abstract
This 54‐year‐old man accidentally sprayed himself with the chemical agent glyphosate, a herbicide derived from the amino acid glycine. He developed disseminated skin lesions 6 hours after the accident. One month later, he developed a symmetrical parkinsonian syndrome. Two years after the initial exposure to glyphosate, magnetic resonance imaging revealed hyperintense signal in the globus pallidus and substantia nigra, bilaterally, on T2‐weighted images. Levodopa/benserazide 500/125 mg daily provided satisfactory clinical outcome.
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DOI: 10.1002/mds.1105
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ISTEX:A61CC955B1E29A4D83222CD652CB5C7A2692D31DLe document en format XML
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He developed disseminated skin lesions 6 hours after the accident. One month later, he developed a symmetrical parkinsonian syndrome. Two years after the initial exposure to glyphosate, magnetic resonance imaging revealed hyperintense signal in the globus pallidus and substantia nigra, bilaterally, on T2‐weighted images. Levodopa/benserazide 500/125 mg daily provided satisfactory clinical outcome.</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><p>A videotape accompanies this article.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Parkinsonism after glycine‐derivate exposure</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Clinical/Scientific Notes</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Parkinsonism after glycine‐derivate exposure</title></titleInfo><name type="personal"><namePart type="given">Egberto R.</namePart><namePart type="family">Barbosa</namePart><affiliation>Divisão de Clínica Neurológica, do Hospital das Clínicas da Faculdade, de Medicina da Universidade, de São Paulo, São Paulo, Brazil</affiliation><description>Correspondence: Rua Sergipe 401, sala 311, São Paulo (SP), Brazil 01243‐001</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Maria D.</namePart><namePart type="family">Leiros da Costa</namePart><affiliation>Divisão de Clínica Neurológica, do Hospital das Clínicas da Faculdade, de Medicina da Universidade, de São Paulo, São Paulo, Brazil</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Luiz A.</namePart><namePart type="family">Bacheschi</namePart><affiliation>Divisão de Clínica Neurológica, do Hospital das Clínicas da Faculdade, de Medicina da Universidade, de São Paulo, São Paulo, Brazil</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Milberto</namePart><namePart type="family">Scaff</namePart><affiliation>Divisão de Clínica Neurológica, do Hospital das Clínicas da Faculdade, de Medicina da Universidade, de São Paulo, São Paulo, Brazil</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Claudia C.</namePart><namePart type="family">Leite</namePart><affiliation>Departamento de Radiologia, da Faculdade de Medicina, da Universidade de São Paulo, São Paulo</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>John Wiley & Sons, Inc.</publisher><place><placeTerm type="text">New York</placeTerm></place><dateIssued encoding="w3cdtf">2001-05</dateIssued><dateCaptured encoding="w3cdtf">1999-10-20</dateCaptured><dateValid encoding="w3cdtf">2000-06-09</dateValid><copyrightDate encoding="w3cdtf">2001</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">4</extent><extent unit="references">30</extent><extent unit="words">1968</extent></physicalDescription><abstract lang="en">This 54‐year‐old man accidentally sprayed himself with the chemical agent glyphosate, a herbicide derived from the amino acid glycine. He developed disseminated skin lesions 6 hours after the accident. One month later, he developed a symmetrical parkinsonian syndrome. Two years after the initial exposure to glyphosate, magnetic resonance imaging revealed hyperintense signal in the globus pallidus and substantia nigra, bilaterally, on T2‐weighted images. Levodopa/benserazide 500/125 mg daily provided satisfactory clinical outcome.</abstract><note type="content">*A videotape accompanies this article.</note><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. 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