Assessment of adaptive functioning in huntington's disease
Identifieur interne : 001993 ( Istex/Corpus ); précédent : 001992; suivant : 001994Assessment of adaptive functioning in huntington's disease
Auteurs : Bylsma ; Johannes Rothlind ; Michelle R. Hall ; Susan E. Folstein ; Jason BrandtSource :
- Movement Disorders [ 0885-3185 ] ; 1993.
English descriptors
- KwdEn :
Abstract
The Huntington's Disease Activities of Daily Living (HD–ADL) scale is a 17‐item informant‐completed instrument for rating adaptive functioning in Huntington's disease (HD) patients. To assess the reliability and clinical correlates of the HD–ADL, it was administered along with the Mini‐Mental State Exam (MMSE) and Quantified Neurological Exam (QNE) to 93 HD patients. The HD‐ADL has high internal consistency (coefficient alpha = 0.91). Principal components factor analysis of the HD‐ADL revealed four factors (General Functioning, Domestic Activities, Home Upkeep, and Family Relationships) accounting for 72% of the total variance. MMSE score, motor impairment score, and duration of disease were the best predictors of HD‐ADL score. Similar results were obtained in an independent replication sample of patients. The HD‐ADL scores correlate with Shoulson and Fahn's total functional capacity (TFC) index (r = −0.89). The HD‐ADL scale is a reliable and valid instrument for assessing adaptive function in HD patients.
Url:
DOI: 10.1002/mds.870080212
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ISTEX:DC6F762EA32F7614FA1F550D36C6EDD2695D32F3Le document en format XML
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="1993">1993</date><biblScope unit="vol">8</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="183">183</biblScope><biblScope unit="page" to="190">190</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">DC6F762EA32F7614FA1F550D36C6EDD2695D32F3</idno><idno type="DOI">10.1002/mds.870080212</idno><idno type="ArticleID">MDS870080212</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Activities of Daily Living</term><term>Huntington's disease</term><term>Mini‐Mental State Exam</term><term>Quantified Neurological Exam</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The Huntington's Disease Activities of Daily Living (HD–ADL) scale is a 17‐item informant‐completed instrument for rating adaptive functioning in Huntington's disease (HD) patients. To assess the reliability and clinical correlates of the HD–ADL, it was administered along with the Mini‐Mental State Exam (MMSE) and Quantified Neurological Exam (QNE) to 93 HD patients. The HD‐ADL has high internal consistency (coefficient alpha = 0.91). Principal components factor analysis of the HD‐ADL revealed four factors (General Functioning, Domestic Activities, Home Upkeep, and Family Relationships) accounting for 72% of the total variance. MMSE score, motor impairment score, and duration of disease were the best predictors of HD‐ADL score. Similar results were obtained in an independent replication sample of patients. The HD‐ADL scores correlate with Shoulson and Fahn's total functional capacity (TFC) index (r = −0.89). The HD‐ADL scale is a reliable and valid instrument for assessing adaptive function in HD patients.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Dr. Bylsma</name><affiliations><json:string>Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland</json:string></affiliations></json:item><json:item><name>Johannes Rothlind</name><affiliations><json:string>Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland</json:string></affiliations></json:item><json:item><name>Michelle R. Hall</name><affiliations><json:string>Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland</json:string></affiliations></json:item><json:item><name>Susan E. Folstein</name><affiliations><json:string>Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland</json:string></affiliations></json:item><json:item><name>Jason Brandt</name><affiliations><json:string>Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Huntington's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Activities of Daily Living</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Mini‐Mental State Exam</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Quantified Neurological Exam</value></json:item></subject><language><json:string>eng</json:string></language><abstract>The Huntington's Disease Activities of Daily Living (HD–ADL) scale is a 17‐item informant‐completed instrument for rating adaptive functioning in Huntington's disease (HD) patients. To assess the reliability and clinical correlates of the HD–ADL, it was administered along with the Mini‐Mental State Exam (MMSE) and Quantified Neurological Exam (QNE) to 93 HD patients. The HD‐ADL has high internal consistency (coefficient alpha = 0.91). Principal components factor analysis of the HD‐ADL revealed four factors (General Functioning, Domestic Activities, Home Upkeep, and Family Relationships) accounting for 72% of the total variance. MMSE score, motor impairment score, and duration of disease were the best predictors of HD‐ADL score. Similar results were obtained in an independent replication sample of patients. The HD‐ADL scores correlate with Shoulson and Fahn's total functional capacity (TFC) index (r = −0.89). 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The HD‐ADL scale is a reliable and valid instrument for assessing adaptive function in HD patients.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Huntington's disease</term></item><item><term>Activities of Daily Living</term></item><item><term>Mini‐Mental State Exam</term></item><item><term>Quantified Neurological Exam</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1993">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/DC6F762EA32F7614FA1F550D36C6EDD2695D32F3/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="tocForm">Movement Disorders</title><title type="subtitle">Official Journal of the Movement Disorder Society</title><title type="short">Mov. 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To assess the reliability and clinical correlates of the HD–ADL, it was administered along with the Mini‐Mental State Exam (MMSE) and Quantified Neurological Exam (QNE) to 93 HD patients. The HD‐ADL has high internal consistency (coefficient alpha = 0.91). Principal components factor analysis of the HD‐ADL revealed four factors (General Functioning, Domestic Activities, Home Upkeep, and Family Relationships) accounting for 72% of the total variance. MMSE score, motor impairment score, and duration of disease were the best predictors of HD‐ADL score. Similar results were obtained in an independent replication sample of patients. The HD‐ADL scores correlate with Shoulson and Fahn's total functional capacity (TFC) index (<i>r</i> = −0.89). The HD‐ADL scale is a reliable and valid instrument for assessing adaptive function in HD patients.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Assessment of adaptive functioning in huntington's disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>ASSESSING ADAPTIVE FUNCTIONING IN HD</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Assessment of adaptive functioning in huntington's disease</title></titleInfo><name type="personal"><namePart type="termsOfAddress">Dr.</namePart><namePart type="family">Bylsma</namePart><affiliation>Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland</affiliation><description>Correspondence: Division of Medical Psychology, Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Meyer 218, 600 North Wolfe Street, Baltimore, MD 21287–7218, U.S.A</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Johannes</namePart><namePart type="family">Rothlind</namePart><affiliation>Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Michelle R.</namePart><namePart type="family">Hall</namePart><affiliation>Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Susan E.</namePart><namePart type="family">Folstein</namePart><affiliation>Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jason</namePart><namePart type="family">Brandt</namePart><affiliation>Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">1993</dateIssued><copyrightDate encoding="w3cdtf">1993</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">4</extent><extent unit="references">13</extent></physicalDescription><abstract lang="en">The Huntington's Disease Activities of Daily Living (HD–ADL) scale is a 17‐item informant‐completed instrument for rating adaptive functioning in Huntington's disease (HD) patients. To assess the reliability and clinical correlates of the HD–ADL, it was administered along with the Mini‐Mental State Exam (MMSE) and Quantified Neurological Exam (QNE) to 93 HD patients. The HD‐ADL has high internal consistency (coefficient alpha = 0.91). Principal components factor analysis of the HD‐ADL revealed four factors (General Functioning, Domestic Activities, Home Upkeep, and Family Relationships) accounting for 72% of the total variance. MMSE score, motor impairment score, and duration of disease were the best predictors of HD‐ADL score. Similar results were obtained in an independent replication sample of patients. The HD‐ADL scores correlate with Shoulson and Fahn's total functional capacity (TFC) index (r = −0.89). The HD‐ADL scale is a reliable and valid instrument for assessing adaptive function in HD patients.</abstract><subject lang="en"><genre>Keywords</genre><topic>Huntington's disease</topic><topic>Activities of Daily Living</topic><topic>Mini‐Mental State Exam</topic><topic>Quantified Neurological Exam</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. 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