Chronic deep brain stimulation in patients with tardive dystonia without a history of major psychosis
Identifieur interne : 001828 ( Istex/Corpus ); précédent : 001827; suivant : 001829Chronic deep brain stimulation in patients with tardive dystonia without a history of major psychosis
Auteurs : Hans-Holger Capelle ; Christian Blahak ; Christoph Schrader ; Hansjörg Baezner ; Thomas M. Kinfe ; Jan Herzog ; Reinhard Dengler ; Joachim K. KraussSource :
- Movement Disorders [ 0885-3185 ] ; 2010-07-30.
English descriptors
Abstract
Tardive dystonia usually occurs with a delay after neuroleptic exposure in patients with major psychosis. A subgroup of patients, however, is given such medication for “mild depression” or “neurasthenia.” Tardive dystonia, in general, may respond favorably to pallidal deep brain stimulation (DBS). Nevertheless, it remains unclear thus far whether or not similar beneficial outcome is achieved with pallidal DBS in different subgroups of patients with tardive dystonia. Four women (mean age 59 years at surgery) underwent stereotactic pallidal DBS in the frame of an observational study. Tardive dystonia occurred secondary to medication with fluspirilene and haloperidol, and injection of long‐acting depot neuroleptics prescribed for mild depression or “nervousness.” Assessment included the Burke‐Fahn‐Marsden (BFM) scale preoperatively and at 12 months follow‐up. Extended follow‐up was available at a mean of 27.3 months postoperatively (range 16–36 months). There were no surgically related complications. All 4 patients experienced sustained statistically significant benefit from pallidal DBS. Mean improvement at 12 months was 77% for the BFM motor score (range, 45–91%; P = 0.043), and 84% at the last available follow‐up (range, 70–91%; P = 0.03). This was paralleled by improvement of the BFM disability score. Chronic pallidal DBS in patients with tardive dystonia without a history of major psychosis provides sustained improvement which is similar to that in other subgroups of patients with tardive dystonia. This effect is stable on extended follow‐up for up to 3 years. © 2010 Movement Disorder Society
Url:
DOI: 10.1002/mds.23123
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ISTEX:D5B338ACF5032196241FB8F13A921551A7A4F90CLe document en format XML
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Kinfe</name><affiliation><mods:affiliation>Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany</mods:affiliation></affiliation></author><author><name sortKey="Herzog, Jan" sort="Herzog, Jan" uniqKey="Herzog J" first="Jan" last="Herzog">Jan Herzog</name><affiliation><mods:affiliation>Department of Neurology, University Hospital Kiel, Kiel, Germany</mods:affiliation></affiliation></author><author><name sortKey="Dengler, Reinhard" sort="Dengler, Reinhard" uniqKey="Dengler R" first="Reinhard" last="Dengler">Reinhard Dengler</name><affiliation><mods:affiliation>Department of Neurology, Medical School Hannover, MHH, Hannover, Germany</mods:affiliation></affiliation></author><author><name sortKey="Krauss, Joachim K" sort="Krauss, Joachim K" uniqKey="Krauss J" first="Joachim K." last="Krauss">Joachim K. Krauss</name><affiliation><mods:affiliation>Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. 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A subgroup of patients, however, is given such medication for “mild depression” or “neurasthenia.” Tardive dystonia, in general, may respond favorably to pallidal deep brain stimulation (DBS). Nevertheless, it remains unclear thus far whether or not similar beneficial outcome is achieved with pallidal DBS in different subgroups of patients with tardive dystonia. Four women (mean age 59 years at surgery) underwent stereotactic pallidal DBS in the frame of an observational study. Tardive dystonia occurred secondary to medication with fluspirilene and haloperidol, and injection of long‐acting depot neuroleptics prescribed for mild depression or “nervousness.” Assessment included the Burke‐Fahn‐Marsden (BFM) scale preoperatively and at 12 months follow‐up. Extended follow‐up was available at a mean of 27.3 months postoperatively (range 16–36 months). There were no surgically related complications. All 4 patients experienced sustained statistically significant benefit from pallidal DBS. Mean improvement at 12 months was 77% for the BFM motor score (range, 45–91%; P = 0.043), and 84% at the last available follow‐up (range, 70–91%; P = 0.03). This was paralleled by improvement of the BFM disability score. Chronic pallidal DBS in patients with tardive dystonia without a history of major psychosis provides sustained improvement which is similar to that in other subgroups of patients with tardive dystonia. This effect is stable on extended follow‐up for up to 3 years. © 2010 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Hans‐Holger Capelle MD</name><affiliations><json:string>Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany</json:string></affiliations></json:item><json:item><name>Christian Blahak MD</name><affiliations><json:string>Department of Neurology, University Hospital Mannheim, Mannheim, Germany</json:string></affiliations></json:item><json:item><name>Christoph Schrader MD</name><affiliations><json:string>Department of Neurology, Medical School Hannover, MHH, Hannover, Germany</json:string></affiliations></json:item><json:item><name>Hansjörg Baezner MD</name><affiliations><json:string>Department of Neurology, University Hospital Mannheim, Mannheim, Germany</json:string></affiliations></json:item><json:item><name>Thomas M. Kinfe MD</name><affiliations><json:string>Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany</json:string></affiliations></json:item><json:item><name>Jan Herzog MD</name><affiliations><json:string>Department of Neurology, University Hospital Kiel, Kiel, Germany</json:string></affiliations></json:item><json:item><name>Reinhard Dengler MD</name><affiliations><json:string>Department of Neurology, Medical School Hannover, MHH, Hannover, Germany</json:string></affiliations></json:item><json:item><name>Joachim K. Krauss MD</name><affiliations><json:string>Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>tardive dystonia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>deep brain stimulation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>major psychosis</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Tardive dystonia usually occurs with a delay after neuroleptic exposure in patients with major psychosis. A subgroup of patients, however, is given such medication for “mild depression” or “neurasthenia.” Tardive dystonia, in general, may respond favorably to pallidal deep brain stimulation (DBS). Nevertheless, it remains unclear thus far whether or not similar beneficial outcome is achieved with pallidal DBS in different subgroups of patients with tardive dystonia. Four women (mean age 59 years at surgery) underwent stereotactic pallidal DBS in the frame of an observational study. Tardive dystonia occurred secondary to medication with fluspirilene and haloperidol, and injection of long‐acting depot neuroleptics prescribed for mild depression or “nervousness.” Assessment included the Burke‐Fahn‐Marsden (BFM) scale preoperatively and at 12 months follow‐up. Extended follow‐up was available at a mean of 27.3 months postoperatively (range 16–36 months). There were no surgically related complications. All 4 patients experienced sustained statistically significant benefit from pallidal DBS. Mean improvement at 12 months was 77% for the BFM motor score (range, 45–91%; P = 0.043), and 84% at the last available follow‐up (range, 70–91%; P = 0.03). This was paralleled by improvement of the BFM disability score. Chronic pallidal DBS in patients with tardive dystonia without a history of major psychosis provides sustained improvement which is similar to that in other subgroups of patients with tardive dystonia. 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A subgroup of patients, however, is given such medication for “mild depression” or “neurasthenia.” Tardive dystonia, in general, may respond favorably to pallidal deep brain stimulation (DBS). Nevertheless, it remains unclear thus far whether or not similar beneficial outcome is achieved with pallidal DBS in different subgroups of patients with tardive dystonia. Four women (mean age 59 years at surgery) underwent stereotactic pallidal DBS in the frame of an observational study. Tardive dystonia occurred secondary to medication with fluspirilene and haloperidol, and injection of long‐acting depot neuroleptics prescribed for mild depression or “nervousness.” Assessment included the Burke‐Fahn‐Marsden (BFM) scale preoperatively and at 12 months follow‐up. Extended follow‐up was available at a mean of 27.3 months postoperatively (range 16–36 months). There were no surgically related complications. All 4 patients experienced sustained statistically significant benefit from pallidal DBS. Mean improvement at 12 months was 77% for the BFM motor score (range, 45–91%; P = 0.043), and 84% at the last available follow‐up (range, 70–91%; P = 0.03). This was paralleled by improvement of the BFM disability score. Chronic pallidal DBS in patients with tardive dystonia without a history of major psychosis provides sustained improvement which is similar to that in other subgroups of patients with tardive dystonia. 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K.</givenNames><familyName>Krauss</familyName><degrees>MD</degrees></personName><contactDetails><email normalForm="krauss.joachim@mh-hannover.de">krauss.joachim@mh‐hannover.de</email></contactDetails></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="DE" type="organization"><unparsedAffiliation>Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="DE" type="organization"><unparsedAffiliation>Department of Neurology, University Hospital Mannheim, Mannheim, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="DE" type="organization"><unparsedAffiliation>Department of Neurology, Medical School Hannover, MHH, Hannover, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af4" countryCode="DE" type="organization"><unparsedAffiliation>Department of Neurology, University Hospital Kiel, Kiel, Germany</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">tardive dystonia</keyword><keyword xml:id="kwd2">deep brain stimulation</keyword><keyword xml:id="kwd3">major psychosis</keyword></keywordGroup><supportingInformation><p> Additional Supporting Information may be found in the online version of this article. </p><supportingInfoItem><mediaResource alt="supporting information" href="urn-x:wiley:08853185:media:mds23123:MDS_23123_sm_Suppinfo"></mediaResource><caption>Supporting Information.</caption></supportingInfoItem></supportingInformation><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Tardive dystonia usually occurs with a delay after neuroleptic exposure in patients with major psychosis. A subgroup of patients, however, is given such medication for “mild depression” or “neurasthenia.” Tardive dystonia, in general, may respond favorably to pallidal deep brain stimulation (DBS). Nevertheless, it remains unclear thus far whether or not similar beneficial outcome is achieved with pallidal DBS in different subgroups of patients with tardive dystonia. Four women (mean age 59 years at surgery) underwent stereotactic pallidal DBS in the frame of an observational study. Tardive dystonia occurred secondary to medication with fluspirilene and haloperidol, and injection of long‐acting depot neuroleptics prescribed for mild depression or “nervousness.” Assessment included the Burke‐Fahn‐Marsden (BFM) scale preoperatively and at 12 months follow‐up. Extended follow‐up was available at a mean of 27.3 months postoperatively (range 16–36 months). There were no surgically related complications. All 4 patients experienced sustained statistically significant benefit from pallidal DBS. Mean improvement at 12 months was 77% for the BFM motor score (range, 45–91%; <i>P</i> = 0.043), and 84% at the last available follow‐up (range, 70–91%; <i>P</i> = 0.03). This was paralleled by improvement of the BFM disability score. Chronic pallidal DBS in patients with tardive dystonia without a history of major psychosis provides sustained improvement which is similar to that in other subgroups of patients with tardive dystonia. This effect is stable on extended follow‐up for up to 3 years. © 2010 Movement Disorder Society</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><p>Potential conflict of interest: Nothing to report.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Chronic deep brain stimulation in patients with tardive dystonia without a history of major psychosis</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>DBS in Patients with Tardive Dystonia</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Chronic deep brain stimulation in patients with tardive dystonia without a history of major psychosis</title></titleInfo><name type="personal"><namePart type="given">Hans‐Holger</namePart><namePart type="family">Capelle</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Christian</namePart><namePart type="family">Blahak</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University Hospital Mannheim, Mannheim, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Christoph</namePart><namePart type="family">Schrader</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Medical School Hannover, MHH, Hannover, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hansjörg</namePart><namePart type="family">Baezner</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University Hospital Mannheim, Mannheim, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Thomas M.</namePart><namePart type="family">Kinfe</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jan</namePart><namePart type="family">Herzog</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University Hospital Kiel, Kiel, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Reinhard</namePart><namePart type="family">Dengler</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Medical School Hannover, MHH, Hannover, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Joachim K.</namePart><namePart type="family">Krauss</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany</affiliation><description>Correspondence: Department of Neurosurgery Medical School Hannover, MHH Carl‐Neuberg‐Straße 1, Hannover 30652, Germany</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2010-07-30</dateIssued><dateCaptured encoding="w3cdtf">2009-02-24</dateCaptured><dateValid encoding="w3cdtf">2010-03-02</dateValid><copyrightDate encoding="w3cdtf">2010</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">2</extent><extent unit="references">26</extent><extent unit="words">3728</extent></physicalDescription><abstract lang="en">Tardive dystonia usually occurs with a delay after neuroleptic exposure in patients with major psychosis. A subgroup of patients, however, is given such medication for “mild depression” or “neurasthenia.” Tardive dystonia, in general, may respond favorably to pallidal deep brain stimulation (DBS). Nevertheless, it remains unclear thus far whether or not similar beneficial outcome is achieved with pallidal DBS in different subgroups of patients with tardive dystonia. Four women (mean age 59 years at surgery) underwent stereotactic pallidal DBS in the frame of an observational study. Tardive dystonia occurred secondary to medication with fluspirilene and haloperidol, and injection of long‐acting depot neuroleptics prescribed for mild depression or “nervousness.” Assessment included the Burke‐Fahn‐Marsden (BFM) scale preoperatively and at 12 months follow‐up. Extended follow‐up was available at a mean of 27.3 months postoperatively (range 16–36 months). There were no surgically related complications. All 4 patients experienced sustained statistically significant benefit from pallidal DBS. Mean improvement at 12 months was 77% for the BFM motor score (range, 45–91%; P = 0.043), and 84% at the last available follow‐up (range, 70–91%; P = 0.03). This was paralleled by improvement of the BFM disability score. Chronic pallidal DBS in patients with tardive dystonia without a history of major psychosis provides sustained improvement which is similar to that in other subgroups of patients with tardive dystonia. This effect is stable on extended follow‐up for up to 3 years. © 2010 Movement Disorder Society</abstract><note type="content">*Potential conflict of interest: Nothing to report.</note><subject lang="en"><genre>Keywords</genre><topic>tardive dystonia</topic><topic>deep brain stimulation</topic><topic>major psychosis</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><note type="content"> Additional Supporting Information may be found in the online version of this article.Supporting Info Item: Supporting Information. - </note><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>25</number></detail><detail type="issue"><caption>no.</caption><number>10</number></detail><extent unit="pages"><start>1477</start><end>1481</end><total>5</total></extent></part></relatedItem><identifier type="istex">D5B338ACF5032196241FB8F13A921551A7A4F90C</identifier><identifier type="DOI">10.1002/mds.23123</identifier><identifier type="ArticleID">MDS23123</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2010 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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