Movement Disorders (revue)

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Complicated recessive dystonia parkinsonism syndromes

Identifieur interne : 001765 ( Istex/Corpus ); précédent : 001764; suivant : 001766

Complicated recessive dystonia parkinsonism syndromes

Auteurs : Susanne A. Schneider ; Kailash P. Bhatia ; John Hardy

Source :

RBID : ISTEX:A91680883B79BEB68301E371ACFBFFE8A7632AFA

English descriptors

Abstract

In addition to pure PD and pure dystonic syndromes, there are a group of disorders with overlapping features. The differential diagnosis of these dystonia parkinsonism syndromes can be complex. In view of the growing list of recognized disorders and recent advances in genetics, we review the autosomal recessive forms of dystonia parkinsonism, summarizing clinical presentations, results of investigations, and response to treatment of gene‐proven cases. We concentrate on PANK2‐, PLA2G6‐, ATP13A2‐, FBX07, TAF1‐, and PRKRA‐associated neurodegeneration. Parkin, PINK1, and DJ‐1 are also briefly reviewed. © 2009 Movement Disorder Society

Url:
DOI: 10.1002/mds.22314

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ISTEX:A91680883B79BEB68301E371ACFBFFE8A7632AFA

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<abstract lang="en">In addition to pure PD and pure dystonic syndromes, there are a group of disorders with overlapping features. The differential diagnosis of these dystonia parkinsonism syndromes can be complex. In view of the growing list of recognized disorders and recent advances in genetics, we review the autosomal recessive forms of dystonia parkinsonism, summarizing clinical presentations, results of investigations, and response to treatment of gene‐proven cases. We concentrate on PANK2‐, PLA2G6‐, ATP13A2‐, FBX07, TAF1‐, and PRKRA‐associated neurodegeneration. Parkin, PINK1, and DJ‐1 are also briefly reviewed. © 2009 Movement Disorder Society</abstract>
<note type="content">*Potential conflict of interest: None reported.</note>
<note type="funding">Brain Research Trust, UK</note>
<note type="funding">Bachmann Strauss Foundation</note>
<subject lang="en">
<genre>Keywords</genre>
<topic>dystonia</topic>
<topic>parkinsonism</topic>
<topic>genetic</topic>
<topic>recessive</topic>
<topic>NBIA</topic>
</subject>
<relatedItem type="host">
<titleInfo>
<title>Movement Disorders</title>
</titleInfo>
<titleInfo type="abbreviated">
<title>Mov. Disord.</title>
</titleInfo>
<subject>
<genre>article category</genre>
<topic>Review</topic>
</subject>
<identifier type="ISSN">0885-3185</identifier>
<identifier type="eISSN">1531-8257</identifier>
<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
<identifier type="PublisherID">MDS</identifier>
<part>
<date>2009</date>
<detail type="volume">
<caption>vol.</caption>
<number>24</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>4</number>
</detail>
<extent unit="pages">
<start>490</start>
<end>499</end>
<total>9</total>
</extent>
</part>
</relatedItem>
<identifier type="istex">A91680883B79BEB68301E371ACFBFFE8A7632AFA</identifier>
<identifier type="DOI">10.1002/mds.22314</identifier>
<identifier type="ArticleID">MDS22314</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2009 Movement Disorder Society</accessCondition>
<recordInfo>
<recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin>
<recordContentSource>WILEY</recordContentSource>
</recordInfo>
</mods>
</metadata>
<serie></serie>
</istex>
</record>

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