Perverted head‐shaking and positional downbeat nystagmus in patients with multiple system atrophy
Identifieur interne : 001731 ( Istex/Corpus ); précédent : 001730; suivant : 001732Perverted head‐shaking and positional downbeat nystagmus in patients with multiple system atrophy
Auteurs : Jee-Young Lee ; Woong-Woo Lee ; Ji Soo Kim ; Hee Jin Kim ; Jin-Kyung Kim ; Beom S. JeonSource :
- Movement Disorders [ 0885-3185 ] ; 2009-07-15.
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- KwdEn :
Abstract
The diagnosis of multiple system atrophy (MSA) is mainly based on the clinical criteria, which are often of little assistance in the early stages of the disease. Positional downbeat nystagmus (pDBN) and perverted head‐shaking nystagmus (pHSN), possible signs of cerebellar dysfunction, may be useful in differentiating MSA from other parkinsonian disorders. To investigate the occurrences of pDBN and pHSN in patients with MSA compared with those in patients with Parkinson's disease (PD). A total of 127 consecutive patients with MSA and 274 patients with PD underwent a video‐oculographic recording of head‐shaking and positional nystagmus over a year. The occurrences of pDBN and pHSN were higher in MSA than in PD. pDBN was more frequently observed in MSA with overt cerebellar signs than in those without, but the occurrence of pHSN did not differ between the MSA groups. pHSN was more frequently observed in MSA‐p without overt cerebellar signs than in PD, but there was no difference in the occurrence of pDBN between them. The presence of pHSN and pDBN may be a clue for the diagnosis of MSA, and pHSN may be helpful in differentiating MSA‐p from PD when the patients do not have overt cerebellar features. © 2009 Movement Disorder Society
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DOI: 10.1002/mds.22559
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Jeon</name><affiliation><mods:affiliation>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</mods:affiliation></affiliation><affiliation><mods:affiliation>Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, South Korea</mods:affiliation></affiliation><affiliation><mods:affiliation>Clinical Research Institute and Movement Disorder Center, Seoul National University Hospital, Seoul, South Korea</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. 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Positional downbeat nystagmus (pDBN) and perverted head‐shaking nystagmus (pHSN), possible signs of cerebellar dysfunction, may be useful in differentiating MSA from other parkinsonian disorders. To investigate the occurrences of pDBN and pHSN in patients with MSA compared with those in patients with Parkinson's disease (PD). A total of 127 consecutive patients with MSA and 274 patients with PD underwent a video‐oculographic recording of head‐shaking and positional nystagmus over a year. The occurrences of pDBN and pHSN were higher in MSA than in PD. pDBN was more frequently observed in MSA with overt cerebellar signs than in those without, but the occurrence of pHSN did not differ between the MSA groups. pHSN was more frequently observed in MSA‐p without overt cerebellar signs than in PD, but there was no difference in the occurrence of pDBN between them. The presence of pHSN and pDBN may be a clue for the diagnosis of MSA, and pHSN may be helpful in differentiating MSA‐p from PD when the patients do not have overt cerebellar features. © 2009 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Jee‐Young Lee MD</name><affiliations><json:string>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</json:string><json:string>Clinical Research Institute and Movement Disorder Center, Seoul National University Hospital, Seoul, South Korea</json:string><json:string>Current Address: Inje University Ilsan Paik Hospital, Goyang, Gyeonggi‐Do, South Korea</json:string></affiliations></json:item><json:item><name>Woong‐Woo Lee MD</name><affiliations><json:string>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</json:string></affiliations></json:item><json:item><name>Ji Soo Kim MD, PhD</name><affiliations><json:string>Department of Neurology, Seoul National University Bundang Hospital, Seoul, South Korea</json:string></affiliations></json:item><json:item><name>Hee Jin Kim MD</name><affiliations><json:string>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</json:string><json:string>Clinical Research Institute and Movement Disorder Center, Seoul National University Hospital, Seoul, South Korea</json:string></affiliations></json:item><json:item><name>Jin‐Kyung Kim BS</name><affiliations><json:string>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</json:string><json:string>Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, South Korea</json:string></affiliations></json:item><json:item><name>Beom S. Jeon MD, PhD</name><affiliations><json:string>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</json:string><json:string>Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, South Korea</json:string><json:string>Clinical Research Institute and Movement Disorder Center, Seoul National University Hospital, Seoul, South Korea</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>multiple system atrophy</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>perverted head‐shaking nystagmus</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>positional downbeat nystagmus</value></json:item></subject><language><json:string>eng</json:string></language><abstract>The diagnosis of multiple system atrophy (MSA) is mainly based on the clinical criteria, which are often of little assistance in the early stages of the disease. Positional downbeat nystagmus (pDBN) and perverted head‐shaking nystagmus (pHSN), possible signs of cerebellar dysfunction, may be useful in differentiating MSA from other parkinsonian disorders. To investigate the occurrences of pDBN and pHSN in patients with MSA compared with those in patients with Parkinson's disease (PD). A total of 127 consecutive patients with MSA and 274 patients with PD underwent a video‐oculographic recording of head‐shaking and positional nystagmus over a year. The occurrences of pDBN and pHSN were higher in MSA than in PD. pDBN was more frequently observed in MSA with overt cerebellar signs than in those without, but the occurrence of pHSN did not differ between the MSA groups. pHSN was more frequently observed in MSA‐p without overt cerebellar signs than in PD, but there was no difference in the occurrence of pDBN between them. The presence of pHSN and pDBN may be a clue for the diagnosis of MSA, and pHSN may be helpful in differentiating MSA‐p from PD when the patients do not have overt cerebellar features. © 2009 Movement Disorder Society</abstract><qualityIndicators><score>6.037</score><pdfVersion>1.3</pdfVersion><pdfPageSize>612 x 810 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>1247</abstractCharCount><pdfWordCount>3613</pdfWordCount><pdfCharCount>22058</pdfCharCount><pdfPageCount>6</pdfPageCount><abstractWordCount>202</abstractWordCount></qualityIndicators><title>Perverted head‐shaking and positional downbeat nystagmus in patients with multiple system atrophy</title><genre><json:string>Serial article</json:string></genre><host><volume>24</volume><pages><total>6</total><last>1295</last><first>1290</first></pages><issn><json:string>0885-3185</json:string></issn><issue>9</issue><subject><json:item><value>Research 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University Hospital, Seoul, South Korea</affiliation><affiliation>Clinical Research Institute and Movement Disorder Center, Seoul National University Hospital, Seoul, South Korea</affiliation><affiliation>Current Address: Inje University Ilsan Paik Hospital, Goyang, Gyeonggi‐Do, South Korea</affiliation></author><author><persName><forename type="first">Woong‐Woo</forename><surname>Lee</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</affiliation></author><author><persName><forename type="first">Ji Soo</forename><surname>Kim</surname><roleName type="degree">MD, PhD</roleName></persName><affiliation>Department of Neurology, Seoul National University Bundang Hospital, Seoul, South Korea</affiliation></author><author><persName><forename type="first">Hee Jin</forename><surname>Kim</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</affiliation><affiliation>Clinical Research Institute and Movement Disorder Center, Seoul National University Hospital, Seoul, South Korea</affiliation></author><author><persName><forename type="first">Jin‐Kyung</forename><surname>Kim</surname><roleName type="degree">BS</roleName></persName><affiliation>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</affiliation><affiliation>Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, South Korea</affiliation></author><author><persName><forename type="first">Beom S.</forename><surname>Jeon</surname><roleName type="degree">MD, PhD</roleName></persName><note type="correspondence"><p>Correspondence: Department of Neurology, Seoul National University Hospital, College of Medicine, Seoul National University, 28, Yongon‐Dong, Chongno‐Gu, Seoul 110‐744, Korea</p></note><affiliation>Department of Neurology, Seoul National University Hospital, 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Positional downbeat nystagmus (pDBN) and perverted head‐shaking nystagmus (pHSN), possible signs of cerebellar dysfunction, may be useful in differentiating MSA from other parkinsonian disorders. To investigate the occurrences of pDBN and pHSN in patients with MSA compared with those in patients with Parkinson's disease (PD). A total of 127 consecutive patients with MSA and 274 patients with PD underwent a video‐oculographic recording of head‐shaking and positional nystagmus over a year. The occurrences of pDBN and pHSN were higher in MSA than in PD. pDBN was more frequently observed in MSA with overt cerebellar signs than in those without, but the occurrence of pHSN did not differ between the MSA groups. pHSN was more frequently observed in MSA‐p without overt cerebellar signs than in PD, but there was no difference in the occurrence of pDBN between them. The presence of pHSN and pDBN may be a clue for the diagnosis of MSA, and pHSN may be helpful in differentiating MSA‐p from PD when the patients do not have overt cerebellar features. © 2009 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>multiple system atrophy</term></item><item><term>Parkinson's disease</term></item><item><term>perverted head‐shaking nystagmus</term></item><item><term>positional downbeat nystagmus</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Research Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2008-11-27">Received</change><change when="2009-02-26">Registration</change><change when="2009-07-15">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/821EDB770F8C0283312BAF10D60F7C25060837B7/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="subtitle">Official Journal of the Movement Disorder Society</title><title type="short">Mov. 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href="file:MDS.MDS22559.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="0"></count><count type="tableTotal" number="1"></count><count type="referenceTotal" number="21"></count><count type="wordTotal" number="4051"></count></countGroup><titleGroup><title type="main" xml:lang="en">Perverted head‐shaking and positional downbeat nystagmus in patients with multiple system atrophy<link href="#fn1"></link></title><title type="short" xml:lang="en">Induced Downbeat Nystagmus in MSA</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1 #af4" currentRef="#curr1"><personName><givenNames>Jee‐Young</givenNames><familyName>Lee</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Woong‐Woo</givenNames><familyName>Lee</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au3" creatorRole="author" 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xml:id="kwd2">Parkinson's disease</keyword><keyword xml:id="kwd3">perverted head‐shaking nystagmus</keyword><keyword xml:id="kwd4">positional downbeat nystagmus</keyword></keywordGroup><fundingInfo><fundingAgency>Seoul National University Hospital Research</fundingAgency></fundingInfo><fundingInfo><fundingAgency>Chung Suk‐Gyoo and Shinyang Cultural Foundation</fundingAgency></fundingInfo><supportingInformation><p> Additional Supporting Information may be found in the online version of this article. </p><supportingInfoItem><mediaResource alt="supporting information" href="urn-x:wiley:08853185:media:mds22559:MDS_22559_sm_supptable"></mediaResource><caption>Clinical profiles of the patients clinically diagnosed with PD, but showing pDBN or pHSN</caption></supportingInfoItem></supportingInformation><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>The diagnosis of multiple system atrophy (MSA) is mainly based on the clinical criteria, which are often of little assistance in the early stages of the disease. Positional downbeat nystagmus (pDBN) and perverted head‐shaking nystagmus (pHSN), possible signs of cerebellar dysfunction, may be useful in differentiating MSA from other parkinsonian disorders. To investigate the occurrences of pDBN and pHSN in patients with MSA compared with those in patients with Parkinson's disease (PD). A total of 127 consecutive patients with MSA and 274 patients with PD underwent a video‐oculographic recording of head‐shaking and positional nystagmus over a year. The occurrences of pDBN and pHSN were higher in MSA than in PD. pDBN was more frequently observed in MSA with overt cerebellar signs than in those without, but the occurrence of pHSN did not differ between the MSA groups. pHSN was more frequently observed in MSA‐p without overt cerebellar signs than in PD, but there was no difference in the occurrence of pDBN between them. The presence of pHSN and pDBN may be a clue for the diagnosis of MSA, and pHSN may be helpful in differentiating MSA‐p from PD when the patients do not have overt cerebellar features. © 2009 Movement Disorder Society</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><p>Potential conflict of interest: Nothing to reported.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Perverted head‐shaking and positional downbeat nystagmus in patients with multiple system atrophy</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Induced Downbeat Nystagmus in MSA</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Perverted head‐shaking and positional downbeat nystagmus in patients with multiple system atrophy</title></titleInfo><name type="personal"><namePart type="given">Jee‐Young</namePart><namePart type="family">Lee</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</affiliation><affiliation>Clinical Research Institute and Movement Disorder Center, Seoul National University Hospital, Seoul, South Korea</affiliation><affiliation>Current Address: Inje University Ilsan Paik Hospital, Goyang, Gyeonggi‐Do, South Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Woong‐Woo</namePart><namePart type="family">Lee</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ji Soo</namePart><namePart type="family">Kim</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurology, Seoul National University Bundang Hospital, Seoul, South Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hee Jin</namePart><namePart type="family">Kim</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</affiliation><affiliation>Clinical Research Institute and Movement Disorder Center, Seoul National University Hospital, Seoul, South Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jin‐Kyung</namePart><namePart type="family">Kim</namePart><namePart type="termsOfAddress">BS</namePart><affiliation>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</affiliation><affiliation>Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, South Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Beom S.</namePart><namePart type="family">Jeon</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</affiliation><affiliation>Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, South Korea</affiliation><affiliation>Clinical Research Institute and Movement Disorder Center, Seoul National University Hospital, Seoul, South Korea</affiliation><description>Correspondence: Department of Neurology, Seoul National University Hospital, College of Medicine, Seoul National University, 28, Yongon‐Dong, Chongno‐Gu, Seoul 110‐744, Korea</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2009-07-15</dateIssued><dateCaptured encoding="w3cdtf">2008-11-27</dateCaptured><dateValid encoding="w3cdtf">2009-02-26</dateValid><copyrightDate encoding="w3cdtf">2009</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">1</extent><extent unit="references">21</extent><extent unit="words">4051</extent></physicalDescription><abstract lang="en">The diagnosis of multiple system atrophy (MSA) is mainly based on the clinical criteria, which are often of little assistance in the early stages of the disease. Positional downbeat nystagmus (pDBN) and perverted head‐shaking nystagmus (pHSN), possible signs of cerebellar dysfunction, may be useful in differentiating MSA from other parkinsonian disorders. To investigate the occurrences of pDBN and pHSN in patients with MSA compared with those in patients with Parkinson's disease (PD). A total of 127 consecutive patients with MSA and 274 patients with PD underwent a video‐oculographic recording of head‐shaking and positional nystagmus over a year. The occurrences of pDBN and pHSN were higher in MSA than in PD. pDBN was more frequently observed in MSA with overt cerebellar signs than in those without, but the occurrence of pHSN did not differ between the MSA groups. pHSN was more frequently observed in MSA‐p without overt cerebellar signs than in PD, but there was no difference in the occurrence of pDBN between them. The presence of pHSN and pDBN may be a clue for the diagnosis of MSA, and pHSN may be helpful in differentiating MSA‐p from PD when the patients do not have overt cerebellar features. © 2009 Movement Disorder Society</abstract><note type="content">*Potential conflict of interest: Nothing to reported.</note><note type="funding">Seoul National University Hospital Research</note><note type="funding">Chung Suk‐Gyoo and Shinyang Cultural Foundation</note><subject lang="en"><genre>Keywords</genre><topic>multiple system atrophy</topic><topic>Parkinson's disease</topic><topic>perverted head‐shaking nystagmus</topic><topic>positional downbeat nystagmus</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><note type="content"> Additional Supporting Information may be found in the online version of this article.Supporting Info Item: Clinical profiles of the patients clinically diagnosed with PD, but showing pDBN or pHSN - </note><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>24</number></detail><detail type="issue"><caption>no.</caption><number>9</number></detail><extent unit="pages"><start>1290</start><end>1295</end><total>6</total></extent></part></relatedItem><identifier type="istex">821EDB770F8C0283312BAF10D60F7C25060837B7</identifier><identifier type="DOI">10.1002/mds.22559</identifier><identifier type="ArticleID">MDS22559</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2009 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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