Mirror movements in patients with Parkinson's disease
Identifieur interne : 001628 ( Istex/Corpus ); précédent : 001627; suivant : 001629Mirror movements in patients with Parkinson's disease
Auteurs : Donatella Ottaviani ; Dorina Tiple ; Antonio Suppa ; Carlo Colosimo ; Giovanni Fabbrini ; Massimo Cincotta ; Giovanni Defazio ; Alfredo BerardelliSource :
- Movement Disorders [ 0885-3185 ] ; 2008-01-30.
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Abstract
Mirror movements (MM) refer to ipsilateral involuntary movements that appear during voluntary activity in contralateral homologous body regions. This study aimed to compare the frequency and distribution of MM in an unselected sample of 274 patients with Parkinson's disease (PD) and 100 healthy subjects, and to check a possible relationship between MM and parkinsonian features. MM of the hand were scored according to the Woods and Teuber scale. The frequency of MM was lower in PD patients than in healthy subjects (29% vs. 71%, P < 0.0001). The distribution of MM also differed in the two groups being often bilateral in healthy subjects, invariably unilateral in PD patients. When parkinsonian signs were unilateral, MM always manifested on the unaffected side; when parkinsonian signs were bilateral, MM manifested on the less affected side. PD patients manifesting MM scored significantly lower on Hohen and Yahr staging than patients without MM. Likewise, there was a significant inverse correlation between the intensity of MM as rated by the Woods and Teuber score and HY staging (r = −0.16, P < 0.01). The low frequency of MM in PD probably relates to the complex interactions between the pathophysiological mechanisms leading to parkinsonian signs and the mechanisms responsible for movement lateralization. © 2007 Movement Disorder Society
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DOI: 10.1002/mds.21825
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uniqKey="Cincotta M" first="Massimo" last="Cincotta">Massimo Cincotta</name><affiliation><mods:affiliation>Unit of Neurology, Santa Maria Nuova Hospital, Florence, Italy</mods:affiliation></affiliation></author><author><name sortKey="Defazio, Giovanni" sort="Defazio, Giovanni" uniqKey="Defazio G" first="Giovanni" last="Defazio">Giovanni Defazio</name><affiliation><mods:affiliation>Department of Neurological and Psychiatric Sciences, University of Bari, Bari, Italy</mods:affiliation></affiliation></author><author><name sortKey="Berardelli, Alfredo" sort="Berardelli, Alfredo" uniqKey="Berardelli A" first="Alfredo" last="Berardelli">Alfredo Berardelli</name><affiliation><mods:affiliation>Department of Neurological Sciences and Neuromed Institute (IRCCS), “La Sapienza” University of Rome, Rome, Italy</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2008-01-30">2008-01-30</date><biblScope unit="vol">23</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="253">253</biblScope><biblScope unit="page" to="258">258</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">529A650FCD8F95002CF73AF81E58554B15059ED2</idno><idno type="DOI">10.1002/mds.21825</idno><idno type="ArticleID">MDS21825</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term><term>motor systems</term><term>movements</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Mirror movements (MM) refer to ipsilateral involuntary movements that appear during voluntary activity in contralateral homologous body regions. This study aimed to compare the frequency and distribution of MM in an unselected sample of 274 patients with Parkinson's disease (PD) and 100 healthy subjects, and to check a possible relationship between MM and parkinsonian features. MM of the hand were scored according to the Woods and Teuber scale. The frequency of MM was lower in PD patients than in healthy subjects (29% vs. 71%, P < 0.0001). The distribution of MM also differed in the two groups being often bilateral in healthy subjects, invariably unilateral in PD patients. When parkinsonian signs were unilateral, MM always manifested on the unaffected side; when parkinsonian signs were bilateral, MM manifested on the less affected side. PD patients manifesting MM scored significantly lower on Hohen and Yahr staging than patients without MM. Likewise, there was a significant inverse correlation between the intensity of MM as rated by the Woods and Teuber score and HY staging (r = −0.16, P < 0.01). The low frequency of MM in PD probably relates to the complex interactions between the pathophysiological mechanisms leading to parkinsonian signs and the mechanisms responsible for movement lateralization. © 2007 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Donatella Ottaviani MD</name><affiliations><json:string>Department of Neurological Sciences and Neuromed Institute (IRCCS), “La Sapienza” University of Rome, Rome, Italy</json:string></affiliations></json:item><json:item><name>Dorina Tiple MD</name><affiliations><json:string>Department of Neurological Sciences and Neuromed Institute (IRCCS), “La Sapienza” University of Rome, Rome, Italy</json:string></affiliations></json:item><json:item><name>Antonio Suppa MD</name><affiliations><json:string>Department of Neurological Sciences and Neuromed Institute (IRCCS), “La Sapienza” University of Rome, Rome, Italy</json:string></affiliations></json:item><json:item><name>Carlo Colosimo MD</name><affiliations><json:string>Department of Neurological Sciences and Neuromed Institute (IRCCS), “La Sapienza” University of Rome, Rome, Italy</json:string></affiliations></json:item><json:item><name>Giovanni Fabbrini MD</name><affiliations><json:string>Department of Neurological Sciences and Neuromed Institute (IRCCS), “La Sapienza” University of Rome, Rome, Italy</json:string></affiliations></json:item><json:item><name>Massimo Cincotta MD</name><affiliations><json:string>Unit of Neurology, Santa Maria Nuova Hospital, Florence, Italy</json:string></affiliations></json:item><json:item><name>Giovanni Defazio MD</name><affiliations><json:string>Department of Neurological and Psychiatric Sciences, University of Bari, Bari, Italy</json:string></affiliations></json:item><json:item><name>Alfredo Berardelli MD</name><affiliations><json:string>Department of Neurological Sciences and Neuromed Institute (IRCCS), “La Sapienza” University of Rome, Rome, Italy</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>motor systems</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>movements</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Mirror movements (MM) refer to ipsilateral involuntary movements that appear during voluntary activity in contralateral homologous body regions. This study aimed to compare the frequency and distribution of MM in an unselected sample of 274 patients with Parkinson's disease (PD) and 100 healthy subjects, and to check a possible relationship between MM and parkinsonian features. MM of the hand were scored according to the Woods and Teuber scale. The frequency of MM was lower in PD patients than in healthy subjects (29% vs. 71%, P > 0.0001). The distribution of MM also differed in the two groups being often bilateral in healthy subjects, invariably unilateral in PD patients. When parkinsonian signs were unilateral, MM always manifested on the unaffected side; when parkinsonian signs were bilateral, MM manifested on the less affected side. PD patients manifesting MM scored significantly lower on Hohen and Yahr staging than patients without MM. Likewise, there was a significant inverse correlation between the intensity of MM as rated by the Woods and Teuber score and HY staging (r = −0.16, P > 0.01). 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This study aimed to compare the frequency and distribution of MM in an unselected sample of 274 patients with Parkinson's disease (PD) and 100 healthy subjects, and to check a possible relationship between MM and parkinsonian features. MM of the hand were scored according to the Woods and Teuber scale. The frequency of MM was lower in PD patients than in healthy subjects (29% vs. 71%, P < 0.0001). The distribution of MM also differed in the two groups being often bilateral in healthy subjects, invariably unilateral in PD patients. When parkinsonian signs were unilateral, MM always manifested on the unaffected side; when parkinsonian signs were bilateral, MM manifested on the less affected side. PD patients manifesting MM scored significantly lower on Hohen and Yahr staging than patients without MM. Likewise, there was a significant inverse correlation between the intensity of MM as rated by the Woods and Teuber score and HY staging (r = −0.16, P < 0.01). 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xml:id="kwd1">motor systems</keyword> <keyword xml:id="kwd2">movements</keyword> <keyword xml:id="kwd3">Parkinson's disease</keyword> </keywordGroup> <fundingInfo> <fundingAgency>“Ente Cassa di Risparmio di Firenze”, Florence, Italy</fundingAgency> </fundingInfo> <abstractGroup> <abstract type="main" xml:lang="en"> <title type="main">Abstract</title> <p>Mirror movements (MM) refer to ipsilateral involuntary movements that appear during voluntary activity in contralateral homologous body regions. This study aimed to compare the frequency and distribution of MM in an unselected sample of 274 patients with Parkinson's disease (PD) and 100 healthy subjects, and to check a possible relationship between MM and parkinsonian features. MM of the hand were scored according to the Woods and Teuber scale. The frequency of MM was lower in PD patients than in healthy subjects (29% vs. 71%, <i>P</i> < 0.0001). The distribution of MM also differed in the two groups being often bilateral in healthy subjects, invariably unilateral in PD patients. When parkinsonian signs were unilateral, MM always manifested on the unaffected side; when parkinsonian signs were bilateral, MM manifested on the less affected side. PD patients manifesting MM scored significantly lower on Hohen and Yahr staging than patients without MM. Likewise, there was a significant inverse correlation between the intensity of MM as rated by the Woods and Teuber score and HY staging (r = −0.16, <i>P</i> < 0.01). The low frequency of MM in PD probably relates to the complex interactions between the pathophysiological mechanisms leading to parkinsonian signs and the mechanisms responsible for movement lateralization. © 2007 Movement Disorder Society</p> </abstract> </abstractGroup> </contentMeta> </header> </component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Mirror movements in patients with Parkinson's disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>MM in Patients with Parkinson's Disease</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Mirror movements in patients with Parkinson's disease</title></titleInfo><name type="personal"><namePart type="given">Donatella</namePart><namePart type="family">Ottaviani</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences and Neuromed Institute (IRCCS), “La Sapienza” University of Rome, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Dorina</namePart><namePart type="family">Tiple</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences and Neuromed Institute (IRCCS), “La Sapienza” University of Rome, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Antonio</namePart><namePart type="family">Suppa</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences and Neuromed Institute (IRCCS), “La Sapienza” University of Rome, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Carlo</namePart><namePart type="family">Colosimo</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences and Neuromed Institute (IRCCS), “La Sapienza” University of Rome, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Giovanni</namePart><namePart type="family">Fabbrini</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences and Neuromed Institute (IRCCS), “La Sapienza” University of Rome, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Massimo</namePart><namePart type="family">Cincotta</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Unit of Neurology, Santa Maria Nuova Hospital, Florence, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Giovanni</namePart><namePart type="family">Defazio</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological and Psychiatric Sciences, University of Bari, Bari, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Alfredo</namePart><namePart type="family">Berardelli</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences and Neuromed Institute (IRCCS), “La Sapienza” University of Rome, Rome, Italy</affiliation><description>Correspondence: Professor of Neurology, Department of Neurological Sciences and Neuromed Institute, “La Sapienza”University of Rome, Viale dell'Università, 30, 00185 Roma, Italy</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2008-01-30</dateIssued><dateCaptured encoding="w3cdtf">2007-06-06</dateCaptured><dateValid encoding="w3cdtf">2007-10-07</dateValid><copyrightDate encoding="w3cdtf">2008</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">3</extent><extent unit="references">30</extent><extent unit="words">4196</extent></physicalDescription><abstract lang="en">Mirror movements (MM) refer to ipsilateral involuntary movements that appear during voluntary activity in contralateral homologous body regions. This study aimed to compare the frequency and distribution of MM in an unselected sample of 274 patients with Parkinson's disease (PD) and 100 healthy subjects, and to check a possible relationship between MM and parkinsonian features. MM of the hand were scored according to the Woods and Teuber scale. The frequency of MM was lower in PD patients than in healthy subjects (29% vs. 71%, P < 0.0001). The distribution of MM also differed in the two groups being often bilateral in healthy subjects, invariably unilateral in PD patients. When parkinsonian signs were unilateral, MM always manifested on the unaffected side; when parkinsonian signs were bilateral, MM manifested on the less affected side. PD patients manifesting MM scored significantly lower on Hohen and Yahr staging than patients without MM. Likewise, there was a significant inverse correlation between the intensity of MM as rated by the Woods and Teuber score and HY staging (r = −0.16, P < 0.01). The low frequency of MM in PD probably relates to the complex interactions between the pathophysiological mechanisms leading to parkinsonian signs and the mechanisms responsible for movement lateralization. © 2007 Movement Disorder Society</abstract><note type="funding">“Ente Cassa di Risparmio di Firenze”, Florence, Italy</note><subject lang="en"><genre>Keywords</genre><topic>motor systems</topic><topic>movements</topic><topic>Parkinson's disease</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>23</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>253</start><end>258</end><total>6</total></extent></part></relatedItem><identifier type="istex">529A650FCD8F95002CF73AF81E58554B15059ED2</identifier><identifier type="DOI">10.1002/mds.21825</identifier><identifier type="ArticleID">MDS21825</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2007 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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