Sympathetic skin response and cardiovascular autonomic function tests in Parkinson's disease and multiple system atrophy with autonomic failure
Identifieur interne : 001538 ( Istex/Corpus ); précédent : 001537; suivant : 001539Sympathetic skin response and cardiovascular autonomic function tests in Parkinson's disease and multiple system atrophy with autonomic failure
Auteurs : M. De Marinis ; F. Stocchi ; B. Gregori ; N. AccorneroSource :
- Movement Disorders [ 0885-3185 ] ; 2000-11.
English descriptors
- KwdEn :
Abstract
The relationship between sympathetic skin response (SSR) and cardiovascular autonomic function tests (CVTs) was investigated in 15 patients with idiopathic Parkinson's disease (PD), 15 patients with clinical evidence of multiple system atrophy (MSA) with autonomic failure, and in 15 healthy control subjects. SSR was elicited by electrical stimulation of the right and left median nerves and simultaneously recorded on the palms of both hands. CVTs included the following sympathetic and parasympathetic tests: orthostatism, head‐up tilt, cold pressor test, deep breathing, Valsalva maneuver, and hyperventilation. The SSR was normal in all patients with PD and control subjects but was abnormal or absent in all patients with MSA. For patients with MSA, SSR latency was significantly longer and amplitude was significantly smaller than that of patients with PD and control subjects. For patients with PD, SSR did not differ from that of control subjects. In these patients, SSR latency was significantly longer and SSR amplitude was smaller when the side with more marked motor symptoms was stimulated, both ipsilaterally and contralaterally to the side of stimulation. A statistically significant difference in SSR latencies and amplitudes was found between patients with PD and control subjects only when motor asymmetries were considered. CVTs showed severe sympathetic and parasympathetic hypofunction in patients with MSA, but not in patients with PD or control subjects. No correlation was found between SSR and CVTs that assess sympathetic function in patients and control subjects. SSR is indicated as an additional test for the evaluation of sympathetic degeneration in patients with MSA.
Url:
DOI: 10.1002/1531-8257(200011)15:6<1215::AID-MDS1023>3.0.CO;2-J
Links to Exploration step
ISTEX:7FD23AED516263F7AEB465EEDD9CB0ECE5724756Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Sympathetic skin response and cardiovascular autonomic function tests in Parkinson's disease and multiple system atrophy with autonomic failure</title><author><name sortKey="De Marinis, M" sort="De Marinis, M" uniqKey="De Marinis M" first="M." last="De Marinis">M. De Marinis</name><affiliation><mods:affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</mods:affiliation></affiliation></author><author><name sortKey="Stocchi, F" sort="Stocchi, F" uniqKey="Stocchi F" first="F." last="Stocchi">F. Stocchi</name><affiliation><mods:affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</mods:affiliation></affiliation></author><author><name sortKey="Gregori, B" sort="Gregori, B" uniqKey="Gregori B" first="B." last="Gregori">B. Gregori</name><affiliation><mods:affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</mods:affiliation></affiliation></author><author><name sortKey="Accornero, N" sort="Accornero, N" uniqKey="Accornero N" first="N." last="Accornero">N. Accornero</name><affiliation><mods:affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:7FD23AED516263F7AEB465EEDD9CB0ECE5724756</idno><date when="2000" year="2000">2000</date><idno type="doi">10.1002/1531-8257(200011)15:6<1215::AID-MDS1023>3.0.CO;2-J</idno><idno type="url">https://api.istex.fr/document/7FD23AED516263F7AEB465EEDD9CB0ECE5724756/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001538</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Sympathetic skin response and cardiovascular autonomic function tests in Parkinson's disease and multiple system atrophy with autonomic failure</title><author><name sortKey="De Marinis, M" sort="De Marinis, M" uniqKey="De Marinis M" first="M." last="De Marinis">M. De Marinis</name><affiliation><mods:affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</mods:affiliation></affiliation></author><author><name sortKey="Stocchi, F" sort="Stocchi, F" uniqKey="Stocchi F" first="F." last="Stocchi">F. Stocchi</name><affiliation><mods:affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</mods:affiliation></affiliation></author><author><name sortKey="Gregori, B" sort="Gregori, B" uniqKey="Gregori B" first="B." last="Gregori">B. Gregori</name><affiliation><mods:affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</mods:affiliation></affiliation></author><author><name sortKey="Accornero, N" sort="Accornero, N" uniqKey="Accornero N" first="N." last="Accornero">N. Accornero</name><affiliation><mods:affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>John Wiley & Sons, Inc.</publisher><pubPlace>New York</pubPlace><date type="published" when="2000-11">2000-11</date><biblScope unit="vol">15</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="1215">1215</biblScope><biblScope unit="page" to="1220">1220</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">7FD23AED516263F7AEB465EEDD9CB0ECE5724756</idno><idno type="DOI">10.1002/1531-8257(200011)15:6<1215::AID-MDS1023>3.0.CO;2-J</idno><idno type="ArticleID">MDS1023</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Autonomic nervous system</term><term>Multiple system atrophy</term><term>Parkinson's disease</term><term>Sympathetic skin response</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The relationship between sympathetic skin response (SSR) and cardiovascular autonomic function tests (CVTs) was investigated in 15 patients with idiopathic Parkinson's disease (PD), 15 patients with clinical evidence of multiple system atrophy (MSA) with autonomic failure, and in 15 healthy control subjects. SSR was elicited by electrical stimulation of the right and left median nerves and simultaneously recorded on the palms of both hands. CVTs included the following sympathetic and parasympathetic tests: orthostatism, head‐up tilt, cold pressor test, deep breathing, Valsalva maneuver, and hyperventilation. The SSR was normal in all patients with PD and control subjects but was abnormal or absent in all patients with MSA. For patients with MSA, SSR latency was significantly longer and amplitude was significantly smaller than that of patients with PD and control subjects. For patients with PD, SSR did not differ from that of control subjects. In these patients, SSR latency was significantly longer and SSR amplitude was smaller when the side with more marked motor symptoms was stimulated, both ipsilaterally and contralaterally to the side of stimulation. A statistically significant difference in SSR latencies and amplitudes was found between patients with PD and control subjects only when motor asymmetries were considered. CVTs showed severe sympathetic and parasympathetic hypofunction in patients with MSA, but not in patients with PD or control subjects. No correlation was found between SSR and CVTs that assess sympathetic function in patients and control subjects. SSR is indicated as an additional test for the evaluation of sympathetic degeneration in patients with MSA.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>M. De Marinis MD</name><affiliations><json:string>Department of Neurological Sciences, La Sapienza University, Rome, Italy</json:string></affiliations></json:item><json:item><name>F. Stocchi MD</name><affiliations><json:string>Department of Neurological Sciences, La Sapienza University, Rome, Italy</json:string></affiliations></json:item><json:item><name>B. Gregori MD</name><affiliations><json:string>Department of Neurological Sciences, La Sapienza University, Rome, Italy</json:string></affiliations></json:item><json:item><name>N. Accornero MD</name><affiliations><json:string>Department of Neurological Sciences, La Sapienza University, Rome, Italy</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Autonomic nervous system</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Multiple system atrophy</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Sympathetic skin response</value></json:item></subject><language><json:string>eng</json:string></language><abstract>The relationship between sympathetic skin response (SSR) and cardiovascular autonomic function tests (CVTs) was investigated in 15 patients with idiopathic Parkinson's disease (PD), 15 patients with clinical evidence of multiple system atrophy (MSA) with autonomic failure, and in 15 healthy control subjects. SSR was elicited by electrical stimulation of the right and left median nerves and simultaneously recorded on the palms of both hands. CVTs included the following sympathetic and parasympathetic tests: orthostatism, head‐up tilt, cold pressor test, deep breathing, Valsalva maneuver, and hyperventilation. The SSR was normal in all patients with PD and control subjects but was abnormal or absent in all patients with MSA. For patients with MSA, SSR latency was significantly longer and amplitude was significantly smaller than that of patients with PD and control subjects. For patients with PD, SSR did not differ from that of control subjects. In these patients, SSR latency was significantly longer and SSR amplitude was smaller when the side with more marked motor symptoms was stimulated, both ipsilaterally and contralaterally to the side of stimulation. A statistically significant difference in SSR latencies and amplitudes was found between patients with PD and control subjects only when motor asymmetries were considered. CVTs showed severe sympathetic and parasympathetic hypofunction in patients with MSA, but not in patients with PD or control subjects. No correlation was found between SSR and CVTs that assess sympathetic function in patients and control subjects. SSR is indicated as an additional test for the evaluation of sympathetic degeneration in patients with MSA.</abstract><qualityIndicators><score>6.213</score><pdfVersion>1.3</pdfVersion><pdfPageSize>612 x 792 pts (letter)</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>1699</abstractCharCount><pdfWordCount>3213</pdfWordCount><pdfCharCount>21394</pdfCharCount><pdfPageCount>6</pdfPageCount><abstractWordCount>252</abstractWordCount></qualityIndicators><title>Sympathetic skin response and cardiovascular autonomic function tests in Parkinson's disease and multiple system atrophy with autonomic failure</title><genre><json:string>Serial article</json:string></genre><host><volume>15</volume><pages><total>6</total><last>1220</last><first>1215</first></pages><issn><json:string>0885-3185</json:string></issn><issue>6</issue><subject><json:item><value>Brief Report</value></json:item></subject><genre></genre><language><json:string>unknown</json:string></language><title>Movement Disorders</title><doi><json:string>10.1002/(ISSN)1531-8257</json:string></doi></host><publicationDate>2000</publicationDate><copyrightDate>2000</copyrightDate><doi><json:string>10.1002/1531-8257(200011)15:6>1215::AID-MDS1023>3.0.CO;2-J</json:string></doi><id>7FD23AED516263F7AEB465EEDD9CB0ECE5724756</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/7FD23AED516263F7AEB465EEDD9CB0ECE5724756/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/7FD23AED516263F7AEB465EEDD9CB0ECE5724756/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/7FD23AED516263F7AEB465EEDD9CB0ECE5724756/fulltext/tei"><teiHeader type="text"><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Sympathetic skin response and cardiovascular autonomic function tests in Parkinson's disease and multiple system atrophy with autonomic failure</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>John Wiley & Sons, Inc.</publisher><pubPlace>New York</pubPlace><availability><p>John Wiley & Sons, Inc.</p></availability><date>2000</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Sympathetic skin response and cardiovascular autonomic function tests in Parkinson's disease and multiple system atrophy with autonomic failure</title><author><persName><forename type="first">M.</forename><surname>De Marinis</surname><roleName type="degree">MD</roleName></persName><note type="correspondence"><p>Correspondence: Via A. Bertoloni 1/E, 00197 Rome, Italy</p></note><affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</affiliation></author><author><persName><forename type="first">F.</forename><surname>Stocchi</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</affiliation></author><author><persName><forename type="first">B.</forename><surname>Gregori</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</affiliation></author><author><persName><forename type="first">N.</forename><surname>Accornero</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</affiliation></author></analytic><monogr><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>John Wiley & Sons, Inc.</publisher><pubPlace>New York</pubPlace><date type="published" when="2000-11"></date><biblScope unit="vol">15</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="1215">1215</biblScope><biblScope unit="page" to="1220">1220</biblScope></imprint></monogr><idno type="istex">7FD23AED516263F7AEB465EEDD9CB0ECE5724756</idno><idno type="DOI">10.1002/1531-8257(200011)15:6<1215::AID-MDS1023>3.0.CO;2-J</idno><idno type="ArticleID">MDS1023</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2000</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>The relationship between sympathetic skin response (SSR) and cardiovascular autonomic function tests (CVTs) was investigated in 15 patients with idiopathic Parkinson's disease (PD), 15 patients with clinical evidence of multiple system atrophy (MSA) with autonomic failure, and in 15 healthy control subjects. SSR was elicited by electrical stimulation of the right and left median nerves and simultaneously recorded on the palms of both hands. CVTs included the following sympathetic and parasympathetic tests: orthostatism, head‐up tilt, cold pressor test, deep breathing, Valsalva maneuver, and hyperventilation. The SSR was normal in all patients with PD and control subjects but was abnormal or absent in all patients with MSA. For patients with MSA, SSR latency was significantly longer and amplitude was significantly smaller than that of patients with PD and control subjects. For patients with PD, SSR did not differ from that of control subjects. In these patients, SSR latency was significantly longer and SSR amplitude was smaller when the side with more marked motor symptoms was stimulated, both ipsilaterally and contralaterally to the side of stimulation. A statistically significant difference in SSR latencies and amplitudes was found between patients with PD and control subjects only when motor asymmetries were considered. CVTs showed severe sympathetic and parasympathetic hypofunction in patients with MSA, but not in patients with PD or control subjects. No correlation was found between SSR and CVTs that assess sympathetic function in patients and control subjects. SSR is indicated as an additional test for the evaluation of sympathetic degeneration in patients with MSA.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Autonomic nervous system</term></item><item><term>Parkinson's disease</term></item><item><term>Multiple system atrophy</term></item><item><term>Sympathetic skin response</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Brief Report</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1999-11-03">Received</change><change when="2000-06-20">Registration</change><change when="2000-11">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/7FD23AED516263F7AEB465EEDD9CB0ECE5724756/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>John Wiley & Sons, Inc.</publisherName><publisherLoc>New York</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="subtitle">Official Journal of the Movement Disorder Society</title><title type="short">Mov. Disord.</title></titleGroup></publicationMeta><publicationMeta level="part" position="60"><doi origin="wiley" registered="yes">10.1002/1531-8257(200011)15:6<>1.0.CO;2-D</doi><numberingGroup><numbering type="journalVolume" number="15">15</numbering><numbering type="journalIssue">6</numbering></numberingGroup><coverDate startDate="2000-11">November 2000</coverDate></publicationMeta><publicationMeta level="unit" type="shortCommunication" position="23" status="forIssue"><doi origin="wiley" registered="yes">10.1002/1531-8257(200011)15:6<1215::AID-MDS1023>3.0.CO;2-J</doi><idGroup><id type="unit" value="MDS1023"></id></idGroup><countGroup><count type="pageTotal" number="6"></count></countGroup><titleGroup><title type="articleCategory">Brief Report</title><title type="tocHeading1">Brief Reports</title></titleGroup><copyright ownership="thirdParty">Copyright © 2000 Movement Disorder Society</copyright><eventGroup><event type="manuscriptReceived" date="1999-11-03"></event><event type="manuscriptRevised" date="2000-01-10"></event><event type="manuscriptAccepted" date="2000-06-20"></event><event type="firstOnline" date="2001-01-17"></event><event type="publishedOnlineFinalForm" date="2001-01-17"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.2 mode:FullText source:HeaderRef result:HeaderRef" date="2010-03-04"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-02"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-31"></event></eventGroup><numberingGroup><numbering type="pageFirst">1215</numbering><numbering type="pageLast">1220</numbering></numberingGroup><correspondenceTo>Via A. Bertoloni 1/E, 00197 Rome, Italy</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:MDS.MDS1023.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="2"></count><count type="tableTotal" number="1"></count><count type="referenceTotal" number="34"></count><count type="wordTotal" number="3110"></count></countGroup><titleGroup><title type="main" xml:lang="en">Sympathetic skin response and cardiovascular autonomic function tests in Parkinson's disease and multiple system atrophy with autonomic failure</title><title type="short" xml:lang="en">SSR and CVTs in PD and MSA</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>M.</givenNames><familyName>De Marinis</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>F.</givenNames><familyName>Stocchi</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1"><personName><givenNames>B.</givenNames><familyName>Gregori</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af1"><personName><givenNames>N.</givenNames><familyName>Accornero</familyName><degrees>MD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="IT" type="organization"><unparsedAffiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">Autonomic nervous system</keyword><keyword xml:id="kwd2">Parkinson's disease</keyword><keyword xml:id="kwd3">Multiple system atrophy</keyword><keyword xml:id="kwd4">Sympathetic skin response</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>The relationship between sympathetic skin response (SSR) and cardiovascular autonomic function tests (CVTs) was investigated in 15 patients with idiopathic Parkinson's disease (PD), 15 patients with clinical evidence of multiple system atrophy (MSA) with autonomic failure, and in 15 healthy control subjects. SSR was elicited by electrical stimulation of the right and left median nerves and simultaneously recorded on the palms of both hands. CVTs included the following sympathetic and parasympathetic tests: orthostatism, head‐up tilt, cold pressor test, deep breathing, Valsalva maneuver, and hyperventilation. The SSR was normal in all patients with PD and control subjects but was abnormal or absent in all patients with MSA. For patients with MSA, SSR latency was significantly longer and amplitude was significantly smaller than that of patients with PD and control subjects. For patients with PD, SSR did not differ from that of control subjects. In these patients, SSR latency was significantly longer and SSR amplitude was smaller when the side with more marked motor symptoms was stimulated, both ipsilaterally and contralaterally to the side of stimulation. A statistically significant difference in SSR latencies and amplitudes was found between patients with PD and control subjects only when motor asymmetries were considered. CVTs showed severe sympathetic and parasympathetic hypofunction in patients with MSA, but not in patients with PD or control subjects. No correlation was found between SSR and CVTs that assess sympathetic function in patients and control subjects. SSR is indicated as an additional test for the evaluation of sympathetic degeneration in patients with MSA.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Sympathetic skin response and cardiovascular autonomic function tests in Parkinson's disease and multiple system atrophy with autonomic failure</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>SSR and CVTs in PD and MSA</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Sympathetic skin response and cardiovascular autonomic function tests in Parkinson's disease and multiple system atrophy with autonomic failure</title></titleInfo><name type="personal"><namePart type="given">M.</namePart><namePart type="family">De Marinis</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</affiliation><description>Correspondence: Via A. Bertoloni 1/E, 00197 Rome, Italy</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F.</namePart><namePart type="family">Stocchi</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B.</namePart><namePart type="family">Gregori</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N.</namePart><namePart type="family">Accornero</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences, La Sapienza University, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">shortCommunication</genre><originInfo><publisher>John Wiley & Sons, Inc.</publisher><place><placeTerm type="text">New York</placeTerm></place><dateIssued encoding="w3cdtf">2000-11</dateIssued><dateCaptured encoding="w3cdtf">1999-11-03</dateCaptured><dateValid encoding="w3cdtf">2000-06-20</dateValid><copyrightDate encoding="w3cdtf">2000</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">2</extent><extent unit="tables">1</extent><extent unit="references">34</extent><extent unit="words">3110</extent></physicalDescription><abstract lang="en">The relationship between sympathetic skin response (SSR) and cardiovascular autonomic function tests (CVTs) was investigated in 15 patients with idiopathic Parkinson's disease (PD), 15 patients with clinical evidence of multiple system atrophy (MSA) with autonomic failure, and in 15 healthy control subjects. SSR was elicited by electrical stimulation of the right and left median nerves and simultaneously recorded on the palms of both hands. CVTs included the following sympathetic and parasympathetic tests: orthostatism, head‐up tilt, cold pressor test, deep breathing, Valsalva maneuver, and hyperventilation. The SSR was normal in all patients with PD and control subjects but was abnormal or absent in all patients with MSA. For patients with MSA, SSR latency was significantly longer and amplitude was significantly smaller than that of patients with PD and control subjects. For patients with PD, SSR did not differ from that of control subjects. In these patients, SSR latency was significantly longer and SSR amplitude was smaller when the side with more marked motor symptoms was stimulated, both ipsilaterally and contralaterally to the side of stimulation. A statistically significant difference in SSR latencies and amplitudes was found between patients with PD and control subjects only when motor asymmetries were considered. CVTs showed severe sympathetic and parasympathetic hypofunction in patients with MSA, but not in patients with PD or control subjects. No correlation was found between SSR and CVTs that assess sympathetic function in patients and control subjects. SSR is indicated as an additional test for the evaluation of sympathetic degeneration in patients with MSA.</abstract><subject lang="en"><genre>Keywords</genre><topic>Autonomic nervous system</topic><topic>Parkinson's disease</topic><topic>Multiple system atrophy</topic><topic>Sympathetic skin response</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2000</date><detail type="volume"><caption>vol.</caption><number>15</number></detail><detail type="issue"><caption>no.</caption><number>6</number></detail><extent unit="pages"><start>1215</start><end>1220</end><total>6</total></extent></part></relatedItem><identifier type="istex">7FD23AED516263F7AEB465EEDD9CB0ECE5724756</identifier><identifier type="DOI">10.1002/1531-8257(200011)15:6<1215::AID-MDS1023>3.0.CO;2-J</identifier><identifier type="ArticleID">MDS1023</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2000 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>John Wiley & Sons, Inc.</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001538 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 001538 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:7FD23AED516263F7AEB465EEDD9CB0ECE5724756
|texte= Sympathetic skin response and cardiovascular autonomic function tests in Parkinson's disease and multiple system atrophy with autonomic failure
}}
| This area was generated with Dilib version V0.6.23. |  |