Movement Disorders (revue)

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Pathological gambling in Parkinson's disease—a review of the literature

Identifieur interne : 001330 ( Istex/Corpus ); précédent : 001329; suivant : 001331

Pathological gambling in Parkinson's disease—a review of the literature

Auteurs : Atbin Djamshidian ; Francisco Cardoso ; Donald Grosset ; Henrietta Bowden-Jones ; Andrew J. Lees

Source :

RBID : ISTEX:F71B531DEBB4BCCAC03F53B87E258C16E7E6C0A8

English descriptors

Abstract

The prevalence of pathological gambling is 3.4% to 6% in treated Parkinson's disease, which is higher than the background population rate. In this review we discuss current evidence to indicate that dopamine agonists are much more likely to trigger this behavior than either L‐dopa or selective monoamine oxidase B inhibitor monotherapy. New insights from recent behavioral and functional imaging studies and possible treatment approaches are also covered. A PubMed literature search using the terms “gambling” and “Parkinson's disease,” “impulse control disorder,” “impulsive compulsive behaviour,” “dopamine agonist,” of individual dopamine agonists, and of ongoing drug trials, using http://www.clinicaltrials.gov, was carried out for the period up to January 2011. © 2011 Movement Disorder Society

Url:
DOI: 10.1002/mds.23821

Links to Exploration step

ISTEX:F71B531DEBB4BCCAC03F53B87E258C16E7E6C0A8

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<url href="http://www.clinicaltrials.gov">http://www.clinicaltrials.gov</url>
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<affiliation>Department of Molecular Neuroscience and Reta Lila Weston Institute for Neurological Studies, University of London, London, United Kingdom</affiliation>
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<abstract lang="en">The prevalence of pathological gambling is 3.4% to 6% in treated Parkinson's disease, which is higher than the background population rate. In this review we discuss current evidence to indicate that dopamine agonists are much more likely to trigger this behavior than either L‐dopa or selective monoamine oxidase B inhibitor monotherapy. New insights from recent behavioral and functional imaging studies and possible treatment approaches are also covered. A PubMed literature search using the terms “gambling” and “Parkinson's disease,” “impulse control disorder,” “impulsive compulsive behaviour,” “dopamine agonist,” of individual dopamine agonists, and of ongoing drug trials, using http://www.clinicaltrials.gov, was carried out for the period up to January 2011. © 2011 Movement Disorder Society</abstract>
<note type="content">*Relevant conflicts of interest/financial disclosures: Nothing to report.</note>
<note type="content">*Full financial disclosures and author roles may be found in the online version of this article.</note>
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<topic>Parkinson's disease</topic>
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<topic>dopamine agonists</topic>
<topic>impulse control</topic>
<topic>adverse effects</topic>
<topic>compulsions</topic>
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