Reliability and validity of ICARS in focal cerebellar lesions
Identifieur interne : 001035 ( Istex/Corpus ); précédent : 001034; suivant : 001036Reliability and validity of ICARS in focal cerebellar lesions
Auteurs : Beate Schoch ; Jens Peter Regel ; Markus Frings ; Marcus Gerwig ; Matthias Maschke ; Markus Neuh User ; Dagmar TimmannSource :
- Movement Disorders [ 0885-3185 ] ; 2007-11-15.
English descriptors
Abstract
To evaluate the therapies for cerebellar diseases appropriate neurological assessment methods to measure severity of ataxia are required. Reliability and validity of the semiquantitative International Cooperative Ataxia Rating Scale (ICARS) has recently been examined in patients with degenerative ataxias. We evaluated reliability (internal consistency), criterion‐related validity and internal construct validity of ICARS for the first time in patients with focal cerebellar lesions (68 patients with surgical lesions and 68 patients with ischemic lesions). For comparison 45 patients with degenerative cerebellar ataxia were included. We found an excellent Cronbach's α as a measurement for internal consistency which was independent from underlying disease. Criterion‐related validity was high. Total ICARS score mirrored clearly the immediate postsurgical worsening and the improvement during the first 3 months after focal surgical and ischemic lesions, whereas in chronic state of focal and degenerative cerebellar disorders ICARS score remained nearly unchanged. Principal component analysis in patients with focal lesions revealed five distinct and clinically meaningful factors which corresponded to the four ICARS subscores and reflected the laterality of kinetic functions. In degenerative disorders, however, the items for the subscore “kinetic function” loaded to more than one factor. Total ICARS score seems to be a useful and valid measurement to describe the time course of ataxia in patients with focal and degenerative disorders affecting primarily the cerebellum. Validity of subscores however is good in focal, but not in degenerative disorders. © 2007 Movement Disorder Society
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DOI: 10.1002/mds.21543
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Reliability and validity of the semiquantitative International Cooperative Ataxia Rating Scale (ICARS) has recently been examined in patients with degenerative ataxias. We evaluated reliability (internal consistency), criterion‐related validity and internal construct validity of ICARS for the first time in patients with focal cerebellar lesions (68 patients with surgical lesions and 68 patients with ischemic lesions). For comparison 45 patients with degenerative cerebellar ataxia were included. We found an excellent Cronbach's α as a measurement for internal consistency which was independent from underlying disease. Criterion‐related validity was high. Total ICARS score mirrored clearly the immediate postsurgical worsening and the improvement during the first 3 months after focal surgical and ischemic lesions, whereas in chronic state of focal and degenerative cerebellar disorders ICARS score remained nearly unchanged. Principal component analysis in patients with focal lesions revealed five distinct and clinically meaningful factors which corresponded to the four ICARS subscores and reflected the laterality of kinetic functions. In degenerative disorders, however, the items for the subscore “kinetic function” loaded to more than one factor. Total ICARS score seems to be a useful and valid measurement to describe the time course of ataxia in patients with focal and degenerative disorders affecting primarily the cerebellum. Validity of subscores however is good in focal, but not in degenerative disorders. © 2007 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Beate Schoch MD</name><affiliations><json:string>Department of Neurosurgery, University of Duisburg‐Essen, Essen, Germany</json:string></affiliations></json:item><json:item><name>Jens Peter Regel MD</name><affiliations><json:string>Department of Neurosurgery, University of Duisburg‐Essen, Essen, Germany</json:string></affiliations></json:item><json:item><name>Markus Frings MD</name><affiliations><json:string>Department of Neurology, University of Duisburg‐Essen, Essen, Germany</json:string></affiliations></json:item><json:item><name>Marcus Gerwig MD</name><affiliations><json:string>Department of Neurology, University of Duisburg‐Essen, Essen, Germany</json:string></affiliations></json:item><json:item><name>Matthias Maschke MD</name><affiliations><json:string>Department of Neurology, University of Duisburg‐Essen, Essen, Germany</json:string><json:string>Department of Neurology, Hospital der Barmherzigen Brüder, Trier, Germany</json:string></affiliations></json:item><json:item><name>Markus Neuhäuser MD</name><affiliations><json:string>Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg‐Essen, Essen, Germany</json:string><json:string>Department of Mathematics and Technology, RheinAhrCampus, Remagen, Germany</json:string></affiliations></json:item><json:item><name>Dagmar Timmann MD</name><affiliations><json:string>Department of Neurology, University of Duisburg‐Essen, Essen, Germany</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>cerebellar lesion</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>ICARS</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>validity</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>reliability</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>principal component analysis</value></json:item></subject><language><json:string>eng</json:string></language><abstract>To evaluate the therapies for cerebellar diseases appropriate neurological assessment methods to measure severity of ataxia are required. Reliability and validity of the semiquantitative International Cooperative Ataxia Rating Scale (ICARS) has recently been examined in patients with degenerative ataxias. We evaluated reliability (internal consistency), criterion‐related validity and internal construct validity of ICARS for the first time in patients with focal cerebellar lesions (68 patients with surgical lesions and 68 patients with ischemic lesions). For comparison 45 patients with degenerative cerebellar ataxia were included. We found an excellent Cronbach's α as a measurement for internal consistency which was independent from underlying disease. Criterion‐related validity was high. Total ICARS score mirrored clearly the immediate postsurgical worsening and the improvement during the first 3 months after focal surgical and ischemic lesions, whereas in chronic state of focal and degenerative cerebellar disorders ICARS score remained nearly unchanged. Principal component analysis in patients with focal lesions revealed five distinct and clinically meaningful factors which corresponded to the four ICARS subscores and reflected the laterality of kinetic functions. In degenerative disorders, however, the items for the subscore “kinetic function” loaded to more than one factor. Total ICARS score seems to be a useful and valid measurement to describe the time course of ataxia in patients with focal and degenerative disorders affecting primarily the cerebellum. 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Reliability and validity of the semiquantitative International Cooperative Ataxia Rating Scale (ICARS) has recently been examined in patients with degenerative ataxias. We evaluated reliability (internal consistency), criterion‐related validity and internal construct validity of ICARS for the first time in patients with focal cerebellar lesions (68 patients with surgical lesions and 68 patients with ischemic lesions). For comparison 45 patients with degenerative cerebellar ataxia were included. We found an excellent Cronbach's α as a measurement for internal consistency which was independent from underlying disease. Criterion‐related validity was high. Total ICARS score mirrored clearly the immediate postsurgical worsening and the improvement during the first 3 months after focal surgical and ischemic lesions, whereas in chronic state of focal and degenerative cerebellar disorders ICARS score remained nearly unchanged. Principal component analysis in patients with focal lesions revealed five distinct and clinically meaningful factors which corresponded to the four ICARS subscores and reflected the laterality of kinetic functions. In degenerative disorders, however, the items for the subscore “kinetic function” loaded to more than one factor. Total ICARS score seems to be a useful and valid measurement to describe the time course of ataxia in patients with focal and degenerative disorders affecting primarily the cerebellum. 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Reliability and validity of the semiquantitative International Cooperative Ataxia Rating Scale (ICARS) has recently been examined in patients with degenerative ataxias. We evaluated reliability (internal consistency), criterion‐related validity and internal construct validity of ICARS for the first time in patients with focal cerebellar lesions (68 patients with surgical lesions and 68 patients with ischemic lesions). For comparison 45 patients with degenerative cerebellar ataxia were included. We found an excellent Cronbach's α as a measurement for internal consistency which was independent from underlying disease. Criterion‐related validity was high. Total ICARS score mirrored clearly the immediate postsurgical worsening and the improvement during the first 3 months after focal surgical and ischemic lesions, whereas in chronic state of focal and degenerative cerebellar disorders ICARS score remained nearly unchanged. Principal component analysis in patients with focal lesions revealed five distinct and clinically meaningful factors which corresponded to the four ICARS subscores and reflected the laterality of kinetic functions. In degenerative disorders, however, the items for the subscore “kinetic function” loaded to more than one factor. Total ICARS score seems to be a useful and valid measurement to describe the time course of ataxia in patients with focal and degenerative disorders affecting primarily the cerebellum. Validity of subscores however is good in focal, but not in degenerative disorders. © 2007 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Reliability and validity of ICARS in focal cerebellar lesions</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>ICARS in Focal Cerebellar Lesions</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Reliability and validity of ICARS in focal cerebellar lesions</title></titleInfo><name type="personal"><namePart type="given">Beate</namePart><namePart type="family">Schoch</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurosurgery, University of Duisburg‐Essen, Essen, Germany</affiliation><description>Correspondence: Department of Neurosurgery, University Duisburg‐Essen, Hufelandstr, 55 / D‐45122 Essen, Germany</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jens Peter</namePart><namePart type="family">Regel</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurosurgery, University of Duisburg‐Essen, Essen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Markus</namePart><namePart type="family">Frings</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University of Duisburg‐Essen, Essen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Marcus</namePart><namePart type="family">Gerwig</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University of Duisburg‐Essen, Essen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Matthias</namePart><namePart type="family">Maschke</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University of Duisburg‐Essen, Essen, Germany</affiliation><affiliation>Department of Neurology, Hospital der Barmherzigen Brüder, Trier, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Markus</namePart><namePart type="family">Neuhäuser</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg‐Essen, Essen, Germany</affiliation><affiliation>Department of Mathematics and Technology, RheinAhrCampus, Remagen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Dagmar</namePart><namePart type="family">Timmann</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University of Duisburg‐Essen, Essen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2007-11-15</dateIssued><dateCaptured encoding="w3cdtf">2007-02-14</dateCaptured><dateValid encoding="w3cdtf">2007-04-01</dateValid><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="tables">4</extent><extent unit="references">30</extent><extent unit="words">4626</extent></physicalDescription><abstract lang="en">To evaluate the therapies for cerebellar diseases appropriate neurological assessment methods to measure severity of ataxia are required. Reliability and validity of the semiquantitative International Cooperative Ataxia Rating Scale (ICARS) has recently been examined in patients with degenerative ataxias. We evaluated reliability (internal consistency), criterion‐related validity and internal construct validity of ICARS for the first time in patients with focal cerebellar lesions (68 patients with surgical lesions and 68 patients with ischemic lesions). For comparison 45 patients with degenerative cerebellar ataxia were included. We found an excellent Cronbach's α as a measurement for internal consistency which was independent from underlying disease. Criterion‐related validity was high. Total ICARS score mirrored clearly the immediate postsurgical worsening and the improvement during the first 3 months after focal surgical and ischemic lesions, whereas in chronic state of focal and degenerative cerebellar disorders ICARS score remained nearly unchanged. Principal component analysis in patients with focal lesions revealed five distinct and clinically meaningful factors which corresponded to the four ICARS subscores and reflected the laterality of kinetic functions. In degenerative disorders, however, the items for the subscore “kinetic function” loaded to more than one factor. Total ICARS score seems to be a useful and valid measurement to describe the time course of ataxia in patients with focal and degenerative disorders affecting primarily the cerebellum. Validity of subscores however is good in focal, but not in degenerative disorders. © 2007 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>cerebellar lesion</topic><topic>ICARS</topic><topic>validity</topic><topic>reliability</topic><topic>principal component analysis</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><detail type="issue"><caption>no.</caption><number>15</number></detail><extent unit="pages"><start>2162</start><end>2169</end><total>8</total></extent></part></relatedItem><identifier type="istex">956C12DE67766C978123188E008824E1AC9588C0</identifier><identifier type="DOI">10.1002/mds.21543</identifier><identifier type="ArticleID">MDS21543</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2007 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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