Subthalamotomy in cervical dystonia: A case study of lesion location and clinical outcome
Identifieur interne : 000F05 ( Istex/Corpus ); précédent : 000F04; suivant : 000F06Subthalamotomy in cervical dystonia: A case study of lesion location and clinical outcome
Auteurs : Christian K. E. Moll ; Wolfgang Hamel ; Christoph B. Ostertag ; Dieter Müller ; Jürgen Finsterbusch ; Andreas K. Engel ; Alexander MünchauSource :
- Movement Disorders [ 0885-3185 ] ; 2008-09-15.
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Abstract
Here we report a 63‐year‐old woman with primary cervical dystonia (CD) whose symptoms subsided for more than 30 years following a unilateral stereotactic subthalamotomy contralateral to the overactive left sternocleidomastoid muscle but then gradually recurred over a period of several months. The aim of the present study was to correlate the topography of the stereotactic lesion with the long lasting therapeutic effect. High‐resolution magnetic resonance imaging and subsequent stereotactic analysis were performed to determine the anatomical localization of the lesion. The primary coagulation focus comprised the posterior subthalamic white matter in the prelemniscal radiation and field H of Forel. Neighboring structures were implicated to various extents. It is suggested that the posterior subthalamic area, with its abundance of interconnecting fibers and related nuclei, represents an effective target for the neurosurgical treatment of CD that may be explored further with deep brain stimulation. © 2008 Movement Disorder Society
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DOI: 10.1002/mds.22088
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Moll</name><affiliation><mods:affiliation>Department of Neurophysiology and Pathophysiology, Center of Experimental Medicine, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Hamel, Wolfgang" sort="Hamel, Wolfgang" uniqKey="Hamel W" first="Wolfgang" last="Hamel">Wolfgang Hamel</name><affiliation><mods:affiliation>Department of Neurosurgery, University Medical Center Hamburg‐ Eppendorf, Hamburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Ostertag, Christoph B" sort="Ostertag, Christoph B" uniqKey="Ostertag C" first="Christoph B." last="Ostertag">Christoph B. 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Engel</name><affiliation><mods:affiliation>Department of Neurophysiology and Pathophysiology, Center of Experimental Medicine, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Munchau, Alexander" sort="Munchau, Alexander" uniqKey="Munchau A" first="Alexander" last="Münchau">Alexander Münchau</name><affiliation><mods:affiliation>Department of Neurology, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. 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The aim of the present study was to correlate the topography of the stereotactic lesion with the long lasting therapeutic effect. High‐resolution magnetic resonance imaging and subsequent stereotactic analysis were performed to determine the anatomical localization of the lesion. The primary coagulation focus comprised the posterior subthalamic white matter in the prelemniscal radiation and field H of Forel. Neighboring structures were implicated to various extents. It is suggested that the posterior subthalamic area, with its abundance of interconnecting fibers and related nuclei, represents an effective target for the neurosurgical treatment of CD that may be explored further with deep brain stimulation. © 2008 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Christian K.E. Moll MD</name><affiliations><json:string>Department of Neurophysiology and Pathophysiology, Center of Experimental Medicine, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany</json:string></affiliations></json:item><json:item><name>Wolfgang Hamel MD</name><affiliations><json:string>Department of Neurosurgery, University Medical Center Hamburg‐ Eppendorf, Hamburg, Germany</json:string></affiliations></json:item><json:item><name>Christoph B. 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The aim of the present study was to correlate the topography of the stereotactic lesion with the long lasting therapeutic effect. High‐resolution magnetic resonance imaging and subsequent stereotactic analysis were performed to determine the anatomical localization of the lesion. The primary coagulation focus comprised the posterior subthalamic white matter in the prelemniscal radiation and field H of Forel. Neighboring structures were implicated to various extents. It is suggested that the posterior subthalamic area, with its abundance of interconnecting fibers and related nuclei, represents an effective target for the neurosurgical treatment of CD that may be explored further with deep brain stimulation. © 2008 Movement Disorder Society</abstract><qualityIndicators><score>6.764</score><pdfVersion>1.3</pdfVersion><pdfPageSize>612 x 810 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>1042</abstractCharCount><pdfWordCount>25524</pdfWordCount><pdfCharCount>166099</pdfCharCount><pdfPageCount>44</pdfPageCount><abstractWordCount>147</abstractWordCount></qualityIndicators><title>Subthalamotomy in cervical dystonia: A case study of lesion location and clinical outcome</title><genre><json:string>Serial article</json:string></genre><host><volume>23</volume><pages><total>6</total><last>1756</last><first>1751</first></pages><issn><json:string>0885-3185</json:string></issn><issue>12</issue><subject><json:item><value>Brief 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Eppendorf, Hamburg, Germany</affiliation></author><author><persName><forename type="first">Jürgen</forename><surname>Finsterbusch</surname><roleName type="degree">PhD</roleName></persName><affiliation>Department of Systems Neuroscience, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany</affiliation><affiliation>Neuroimage Nord, University Medical Centers Hamburg‐Kiel‐Lübeck, Germany</affiliation></author><author><persName><forename type="first">Andreas K.</forename><surname>Engel</surname><roleName type="degree">MD, PhD</roleName></persName><affiliation>Department of Neurophysiology and Pathophysiology, Center of Experimental Medicine, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany</affiliation></author><author><persName><forename type="first">Alexander</forename><surname>Münchau</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, University Medical Center Hamburg‐Eppendorf, Hamburg, 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The aim of the present study was to correlate the topography of the stereotactic lesion with the long lasting therapeutic effect. High‐resolution magnetic resonance imaging and subsequent stereotactic analysis were performed to determine the anatomical localization of the lesion. The primary coagulation focus comprised the posterior subthalamic white matter in the prelemniscal radiation and field H of Forel. Neighboring structures were implicated to various extents. 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affiliationRef="#af6"><personName><givenNames>Alexander</givenNames><familyName>Münchau</familyName><degrees>MD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="DE" type="organization"><unparsedAffiliation>Department of Neurophysiology and Pathophysiology, Center of Experimental Medicine, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="DE" type="organization"><unparsedAffiliation>Department of Neurosurgery, University Medical Center Hamburg‐ Eppendorf, Hamburg, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="DE" type="organization"><unparsedAffiliation>Department of Stereotactic and Functional Neurosurgery, University‐Hospital Freiburg, Freiburg, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af4" countryCode="DE" type="organization"><unparsedAffiliation>Department of Systems Neuroscience, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af5" countryCode="DE" type="organization"><unparsedAffiliation>Neuroimage Nord, University Medical Centers Hamburg‐Kiel‐Lübeck, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af6" countryCode="DE" type="organization"><unparsedAffiliation>Department of Neurology, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">cervical dystonia</keyword><keyword xml:id="kwd2">subthalamotomy</keyword><keyword xml:id="kwd3">subthalamic nucleus</keyword><keyword xml:id="kwd4">stereotaxy</keyword><keyword xml:id="kwd5">magnetic resonance imaging</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Here we report a 63‐year‐old woman with primary cervical dystonia (CD) whose symptoms subsided for more than 30 years following a unilateral stereotactic subthalamotomy contralateral to the overactive left sternocleidomastoid muscle but then gradually recurred over a period of several months. The aim of the present study was to correlate the topography of the stereotactic lesion with the long lasting therapeutic effect. High‐resolution magnetic resonance imaging and subsequent stereotactic analysis were performed to determine the anatomical localization of the lesion. The primary coagulation focus comprised the posterior subthalamic white matter in the prelemniscal radiation and field H of Forel. Neighboring structures were implicated to various extents. It is suggested that the posterior subthalamic area, with its abundance of interconnecting fibers and related nuclei, represents an effective target for the neurosurgical treatment of CD that may be explored further with deep brain stimulation. © 2008 Movement Disorder Society</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><p>Potential conflict of interest: None reported.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Subthalamotomy in cervical dystonia: A case study of lesion location and clinical outcome</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Subthalamotomy in Cervical Dystonia</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Subthalamotomy in cervical dystonia: A case study of lesion location and clinical outcome</title></titleInfo><name type="personal"><namePart type="given">Christian K.E.</namePart><namePart type="family">Moll</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurophysiology and Pathophysiology, Center of Experimental Medicine, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany</affiliation><description>Correspondence: Department of Neurophysiology and Pathophysiology, Basal Ganglia Physiology Group, Center of Experimental Medicine, University Medical Center Hamburg‐Eppendorf, Martinistraße 52, 20246 Hamburg, Germany</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Wolfgang</namePart><namePart type="family">Hamel</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurosurgery, University Medical Center Hamburg‐ Eppendorf, Hamburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Christoph B.</namePart><namePart type="family">Ostertag</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Stereotactic and Functional Neurosurgery, University‐Hospital Freiburg, Freiburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Dieter</namePart><namePart type="family">Müller</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurosurgery, University Medical Center Hamburg‐ Eppendorf, Hamburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jürgen</namePart><namePart type="family">Finsterbusch</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Systems Neuroscience, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany</affiliation><affiliation>Neuroimage Nord, University Medical Centers Hamburg‐Kiel‐Lübeck, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Andreas K.</namePart><namePart type="family">Engel</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurophysiology and Pathophysiology, Center of Experimental Medicine, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Alexander</namePart><namePart type="family">Münchau</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2008-09-15</dateIssued><dateCaptured encoding="w3cdtf">2007-04-02</dateCaptured><dateValid encoding="w3cdtf">2008-03-23</dateValid><copyrightDate encoding="w3cdtf">2008</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="references">27</extent><extent unit="words">3352</extent></physicalDescription><abstract lang="en">Here we report a 63‐year‐old woman with primary cervical dystonia (CD) whose symptoms subsided for more than 30 years following a unilateral stereotactic subthalamotomy contralateral to the overactive left sternocleidomastoid muscle but then gradually recurred over a period of several months. The aim of the present study was to correlate the topography of the stereotactic lesion with the long lasting therapeutic effect. High‐resolution magnetic resonance imaging and subsequent stereotactic analysis were performed to determine the anatomical localization of the lesion. The primary coagulation focus comprised the posterior subthalamic white matter in the prelemniscal radiation and field H of Forel. Neighboring structures were implicated to various extents. It is suggested that the posterior subthalamic area, with its abundance of interconnecting fibers and related nuclei, represents an effective target for the neurosurgical treatment of CD that may be explored further with deep brain stimulation. © 2008 Movement Disorder Society</abstract><note type="content">*Potential conflict of interest: None reported.</note><subject lang="en"><genre>Keywords</genre><topic>cervical dystonia</topic><topic>subthalamotomy</topic><topic>subthalamic nucleus</topic><topic>stereotaxy</topic><topic>magnetic resonance imaging</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>23</number></detail><detail type="issue"><caption>no.</caption><number>12</number></detail><extent unit="pages"><start>1751</start><end>1756</end><total>6</total></extent></part></relatedItem><identifier type="istex">32609DADCC4ACB39D5836B185FB481111CD6A71A</identifier><identifier type="DOI">10.1002/mds.22088</identifier><identifier type="ArticleID">MDS22088</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2008 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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