Field validation of a method for population screening of parkinsonism
Identifieur interne : 000B94 ( Istex/Corpus ); précédent : 000B93; suivant : 000B95Field validation of a method for population screening of parkinsonism
Auteurs : Maria Dolores Sevillano ; Jesús De Pedro-Cuesta ; Jacinto Duarte ; Luis Erik ClaveríaSource :
- Movement Disorders [ 0885-3185 ] ; 2002-03.
English descriptors
- KwdEn :
Abstract
We sought to validate an instrument and two application procedures for screening for prevalence of parkinsonism in conjunction with a door‐to‐door survey in Cantalejo, Spain. Residents in Cantalejo aged 40 years or older were assigned to three groups specifically designed to optimise case‐finding and cost/efficiency. A nine‐item questionnaire aimed at identifying parkinsonism‐related symptoms was administered and collected door‐to‐door by laymen and repeated by specialists at a medical facility before neurological examination. Diagnoses were then established and confirmed after a 3‐year follow‐up. Different indices for and concordance of answers were studied for both applications in groups of 25 individuals with parkinsonism. The scoring procedure was updated using the prevalence community sample of parkinsonism. Whereas the application administered by laymen showed, using the same cut‐off scores, a higher sensitivity for parkinsonism than that administered by trained personnel, it yielded a lower positive predictive value for parkinsonism diagnosed during the study, i.e., at a 30‐point cut‐off (96% vs. 80% and 15% vs. 76%, respectively). Concordance was ≥64% with κ ≥0.316 and P ≤0.031 for six questions. Instrument sensitivity, determined by different cut‐off scores, had a high impact on PD detection, observed M/F ratio, severity, and mean age at onset. Choice of screening method or application can considerably affect prevalence measurements and disease natural history parameters described in PD surveys. © 2002 Movement Disorder Society
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DOI: 10.1002/mds.10088
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ISTEX:B74E6647E2B1D7F21925390EC524BAB3BE0EA656Le document en format XML
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Residents in Cantalejo aged 40 years or older were assigned to three groups specifically designed to optimise case‐finding and cost/efficiency. A nine‐item questionnaire aimed at identifying parkinsonism‐related symptoms was administered and collected door‐to‐door by laymen and repeated by specialists at a medical facility before neurological examination. Diagnoses were then established and confirmed after a 3‐year follow‐up. Different indices for and concordance of answers were studied for both applications in groups of 25 individuals with parkinsonism. The scoring procedure was updated using the prevalence community sample of parkinsonism. Whereas the application administered by laymen showed, using the same cut‐off scores, a higher sensitivity for parkinsonism than that administered by trained personnel, it yielded a lower positive predictive value for parkinsonism diagnosed during the study, i.e., at a 30‐point cut‐off (96% vs. 80% and 15% vs. 76%, respectively). Concordance was ≥64% with κ ≥0.316 and P ≤0.031 for six questions. Instrument sensitivity, determined by different cut‐off scores, had a high impact on PD detection, observed M/F ratio, severity, and mean age at onset. Choice of screening method or application can considerably affect prevalence measurements and disease natural history parameters described in PD surveys. © 2002 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Maria Dolores Sevillano MD, MPH, PhD</name><affiliations><json:string>Department of Applied Epidemiology, National Centre for Epidemiology, Carlos III Institute of Public Health, Madrid, Spain</json:string></affiliations></json:item><json:item><name>Jesús de Pedro‐Cuesta MD, PhD</name><affiliations><json:string>Department of Applied Epidemiology, National Centre for Epidemiology, Carlos III Institute of Public Health, Madrid, Spain</json:string><json:string>NEUROTEC, Division of Neurology, Huddinge University Hospital, Karolinska Institute, Huddinge, Sweden</json:string></affiliations></json:item><json:item><name>Jacinto Duarte MD</name><affiliations><json:string>Department of Neurology, Segovia General Hospital, Segovia, Spain</json:string></affiliations></json:item><json:item><name>Luis Erik Clavería MD</name><affiliations><json:string>Department of Neurology, Segovia General Hospital, Segovia, Spain</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>epidemiology</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>parkinsonism</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>door‐to‐door surveys</value></json:item></subject><language><json:string>eng</json:string></language><abstract>We sought to validate an instrument and two application procedures for screening for prevalence of parkinsonism in conjunction with a door‐to‐door survey in Cantalejo, Spain. 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Concordance was ≥64% with κ ≥0.316 and P ≤0.031 for six questions. Instrument sensitivity, determined by different cut‐off scores, had a high impact on PD detection, observed M/F ratio, severity, and mean age at onset. 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Residents in Cantalejo aged 40 years or older were assigned to three groups specifically designed to optimise case‐finding and cost/efficiency. A nine‐item questionnaire aimed at identifying parkinsonism‐related symptoms was administered and collected door‐to‐door by laymen and repeated by specialists at a medical facility before neurological examination. Diagnoses were then established and confirmed after a 3‐year follow‐up. Different indices for and concordance of answers were studied for both applications in groups of 25 individuals with parkinsonism. The scoring procedure was updated using the prevalence community sample of parkinsonism. Whereas the application administered by laymen showed, using the same cut‐off scores, a higher sensitivity for parkinsonism than that administered by trained personnel, it yielded a lower positive predictive value for parkinsonism diagnosed during the study, i.e., at a 30‐point cut‐off (96% vs. 80% and 15% vs. 76%, respectively). Concordance was ≥64% with κ ≥0.316 and P ≤0.031 for six questions. Instrument sensitivity, determined by different cut‐off scores, had a high impact on PD detection, observed M/F ratio, severity, and mean age at onset. Choice of screening method or application can considerably affect prevalence measurements and disease natural history parameters described in PD surveys. © 2002 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>epidemiology</term></item><item><term>parkinsonism</term></item><item><term>door‐to‐door surveys</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Research Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2000-09-15">Received</change><change when="2001-10-15">Registration</change><change when="2002-03">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/B74E6647E2B1D7F21925390EC524BAB3BE0EA656/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>New York</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="subtitle">Official Journal of the Movement Disorder Society</title><title type="short">Mov. 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Residents in Cantalejo aged 40 years or older were assigned to three groups specifically designed to optimise case‐finding and cost/efficiency. A nine‐item questionnaire aimed at identifying parkinsonism‐related symptoms was administered and collected door‐to‐door by laymen and repeated by specialists at a medical facility before neurological examination. Diagnoses were then established and confirmed after a 3‐year follow‐up. Different indices for and concordance of answers were studied for both applications in groups of 25 individuals with parkinsonism. The scoring procedure was updated using the prevalence community sample of parkinsonism. Whereas the application administered by laymen showed, using the same cut‐off scores, a higher sensitivity for parkinsonism than that administered by trained personnel, it yielded a lower positive predictive value for parkinsonism diagnosed during the study, i.e., at a 30‐point cut‐off (96% vs. 80% and 15% vs. 76%, respectively). Concordance was ≥64% with κ ≥0.316 and <i>P</i> ≤0.031 for six questions. Instrument sensitivity, determined by different cut‐off scores, had a high impact on PD detection, observed M/F ratio, severity, and mean age at onset. Choice of screening method or application can considerably affect prevalence measurements and disease natural history parameters described in PD surveys. © 2002 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Field validation of a method for population screening of parkinsonism</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Population Screening of Parkinsonism</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Field validation of a method for population screening of parkinsonism</title></titleInfo><name type="personal"><namePart type="given">Maria Dolores</namePart><namePart type="family">Sevillano</namePart><namePart type="termsOfAddress">MD, MPH, PhD</namePart><affiliation>Department of Applied Epidemiology, National Centre for Epidemiology, Carlos III Institute of Public Health, Madrid, Spain</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jesús</namePart><namePart type="family">de Pedro‐Cuesta</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Applied Epidemiology, National Centre for Epidemiology, Carlos III Institute of Public Health, Madrid, Spain</affiliation><affiliation>NEUROTEC, Division of Neurology, Huddinge University Hospital, Karolinska Institute, Huddinge, Sweden</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jacinto</namePart><namePart type="family">Duarte</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Segovia General Hospital, Segovia, Spain</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Luis Erik</namePart><namePart type="family">Clavería</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Segovia General Hospital, Segovia, Spain</affiliation><description>Correspondence: Sección de Neurología, Hospital General de Segovia, Ctra de Avila s/n, 40001 Segovia, Spain</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">New York</placeTerm></place><dateIssued encoding="w3cdtf">2002-03</dateIssued><dateCaptured encoding="w3cdtf">2000-09-15</dateCaptured><dateValid encoding="w3cdtf">2001-10-15</dateValid><copyrightDate encoding="w3cdtf">2002</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">3</extent><extent unit="tables">4</extent><extent unit="references">25</extent><extent unit="words">3589</extent></physicalDescription><abstract lang="en">We sought to validate an instrument and two application procedures for screening for prevalence of parkinsonism in conjunction with a door‐to‐door survey in Cantalejo, Spain. Residents in Cantalejo aged 40 years or older were assigned to three groups specifically designed to optimise case‐finding and cost/efficiency. A nine‐item questionnaire aimed at identifying parkinsonism‐related symptoms was administered and collected door‐to‐door by laymen and repeated by specialists at a medical facility before neurological examination. Diagnoses were then established and confirmed after a 3‐year follow‐up. Different indices for and concordance of answers were studied for both applications in groups of 25 individuals with parkinsonism. The scoring procedure was updated using the prevalence community sample of parkinsonism. Whereas the application administered by laymen showed, using the same cut‐off scores, a higher sensitivity for parkinsonism than that administered by trained personnel, it yielded a lower positive predictive value for parkinsonism diagnosed during the study, i.e., at a 30‐point cut‐off (96% vs. 80% and 15% vs. 76%, respectively). Concordance was ≥64% with κ ≥0.316 and P ≤0.031 for six questions. Instrument sensitivity, determined by different cut‐off scores, had a high impact on PD detection, observed M/F ratio, severity, and mean age at onset. Choice of screening method or application can considerably affect prevalence measurements and disease natural history parameters described in PD surveys. © 2002 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>epidemiology</topic><topic>parkinsonism</topic><topic>door‐to‐door surveys</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>258</start><end>264</end><total>7</total></extent></part></relatedItem><identifier type="istex">B74E6647E2B1D7F21925390EC524BAB3BE0EA656</identifier><identifier type="DOI">10.1002/mds.10088</identifier><identifier type="ArticleID">MDS10088</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2002 Movement Disorders Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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