Nighttime sleep problems and daytime sleepiness in Parkinson's disease
Identifieur interne : 000B24 ( Istex/Corpus ); précédent : 000B23; suivant : 000B25Nighttime sleep problems and daytime sleepiness in Parkinson's disease
Auteurs : Dagmar Verbaan ; Stephanie M. Van Rooden ; Martine Visser ; Johan Marinus ; Jacobus J. Van HiltenSource :
- Movement Disorders [ 0885-3185 ] ; 2008-01.
English descriptors
Abstract
Our objective is to evaluate nighttime sleep problems (NSP) and daytime sleepiness (DS) in patients with Parkinson's disease (PD) compared to controls, and to assess relations with demographic, disease‐related, and clinical characteristics in patients. NSP and DS were evaluated with the SCOPA‐SLEEP questionnaire in PD patients and controls. In patients, other disease‐related and clinical characteristics were also evaluated. Four hundred twenty PD patients [mean (SD) age 61.1 (11.5) years] and 150 controls [mean (SD) age 60.9 (9.9) years] participated in the study. Compared to controls, a significantly greater proportion of patients had excessive DS (EDS) (43 vs. 10%), excessive NSP (ENSP) (27 vs. 9%), or used sleep medication (17 vs. 12%). Difficulties with falling asleep were similar in both groups. In both patients and controls, women experienced more NSP than men. In patients, depressive symptoms accounted for 21% of NSP variance and was the major contributor to the total explained variance (30%). Furthermore, NSP were related to dopamine‐agonist and levodopa dose, whereas DS was related to age, dopamine‐agonist dose, and disease severity. NSP and DS occur frequently in PD, with EDS being reported more commonly than ENSP. No strong relations were found between DS and demographic or clinical variables. The strong relation between NSP and depressive symptoms in PD calls for future studies to explore the nature of this relation. © 2007 Movement Disorder Society
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DOI: 10.1002/mds.21727
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ISTEX:BEE00B7711D7D7DF1865090033D443D02661DFA4Le document en format XML
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Van Rooden</name><affiliation><mods:affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Visser, Martine" sort="Visser, Martine" uniqKey="Visser M" first="Martine" last="Visser">Martine Visser</name><affiliation><mods:affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Marinus, Johan" sort="Marinus, Johan" uniqKey="Marinus J" first="Johan" last="Marinus">Johan Marinus</name><affiliation><mods:affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Van Hilten, Jacobus J" sort="Van Hilten, Jacobus J" uniqKey="Van Hilten J" first="Jacobus J." last="Van Hilten">Jacobus J. 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Van Rooden</name><affiliation><mods:affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Visser, Martine" sort="Visser, Martine" uniqKey="Visser M" first="Martine" last="Visser">Martine Visser</name><affiliation><mods:affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Marinus, Johan" sort="Marinus, Johan" uniqKey="Marinus J" first="Johan" last="Marinus">Johan Marinus</name><affiliation><mods:affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Van Hilten, Jacobus J" sort="Van Hilten, Jacobus J" uniqKey="Van Hilten J" first="Jacobus J." last="Van Hilten">Jacobus J. 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NSP and DS were evaluated with the SCOPA‐SLEEP questionnaire in PD patients and controls. In patients, other disease‐related and clinical characteristics were also evaluated. Four hundred twenty PD patients [mean (SD) age 61.1 (11.5) years] and 150 controls [mean (SD) age 60.9 (9.9) years] participated in the study. Compared to controls, a significantly greater proportion of patients had excessive DS (EDS) (43 vs. 10%), excessive NSP (ENSP) (27 vs. 9%), or used sleep medication (17 vs. 12%). Difficulties with falling asleep were similar in both groups. In both patients and controls, women experienced more NSP than men. In patients, depressive symptoms accounted for 21% of NSP variance and was the major contributor to the total explained variance (30%). Furthermore, NSP were related to dopamine‐agonist and levodopa dose, whereas DS was related to age, dopamine‐agonist dose, and disease severity. NSP and DS occur frequently in PD, with EDS being reported more commonly than ENSP. No strong relations were found between DS and demographic or clinical variables. The strong relation between NSP and depressive symptoms in PD calls for future studies to explore the nature of this relation. © 2007 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Dagmar Verbaan MSc</name><affiliations><json:string>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</json:string></affiliations></json:item><json:item><name>Stephanie M. van Rooden MSc</name><affiliations><json:string>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</json:string></affiliations></json:item><json:item><name>Martine Visser PhD</name><affiliations><json:string>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</json:string></affiliations></json:item><json:item><name>Johan Marinus PhD</name><affiliations><json:string>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</json:string></affiliations></json:item><json:item><name>Jacobus J. van Hilten MD, PhD</name><affiliations><json:string>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>sleep</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>SCOPA‐SLEEP</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>insomnia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>excessive daytime sleepiness</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Our objective is to evaluate nighttime sleep problems (NSP) and daytime sleepiness (DS) in patients with Parkinson's disease (PD) compared to controls, and to assess relations with demographic, disease‐related, and clinical characteristics in patients. NSP and DS were evaluated with the SCOPA‐SLEEP questionnaire in PD patients and controls. In patients, other disease‐related and clinical characteristics were also evaluated. Four hundred twenty PD patients [mean (SD) age 61.1 (11.5) years] and 150 controls [mean (SD) age 60.9 (9.9) years] participated in the study. Compared to controls, a significantly greater proportion of patients had excessive DS (EDS) (43 vs. 10%), excessive NSP (ENSP) (27 vs. 9%), or used sleep medication (17 vs. 12%). Difficulties with falling asleep were similar in both groups. In both patients and controls, women experienced more NSP than men. In patients, depressive symptoms accounted for 21% of NSP variance and was the major contributor to the total explained variance (30%). Furthermore, NSP were related to dopamine‐agonist and levodopa dose, whereas DS was related to age, dopamine‐agonist dose, and disease severity. NSP and DS occur frequently in PD, with EDS being reported more commonly than ENSP. No strong relations were found between DS and demographic or clinical variables. 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WAR05‐0120;</note><note>Netherlands Organization of Scientific Research - No. NWO, project no. 0940‐33‐021;</note><note>van Alkemade‐Keuls Foundation</note><note>Dutch Parkinson's Disease Society</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Nighttime sleep problems and daytime sleepiness in Parkinson's disease</title><author><persName><forename type="first">Dagmar</forename><surname>Verbaan</surname><roleName type="degree">MSc</roleName></persName><note type="correspondence"><p>Correspondence: Department of Neurology, K5Q‐92, Leiden University Medical Center, P.O. 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Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2008-01"></date><biblScope unit="vol">23</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="35">35</biblScope><biblScope unit="page" to="41">41</biblScope></imprint></monogr><idno type="istex">BEE00B7711D7D7DF1865090033D443D02661DFA4</idno><idno type="DOI">10.1002/mds.21727</idno><idno type="ArticleID">MDS21727</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2008</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Our objective is to evaluate nighttime sleep problems (NSP) and daytime sleepiness (DS) in patients with Parkinson's disease (PD) compared to controls, and to assess relations with demographic, disease‐related, and clinical characteristics in patients. NSP and DS were evaluated with the SCOPA‐SLEEP questionnaire in PD patients and controls. In patients, other disease‐related and clinical characteristics were also evaluated. Four hundred twenty PD patients [mean (SD) age 61.1 (11.5) years] and 150 controls [mean (SD) age 60.9 (9.9) years] participated in the study. Compared to controls, a significantly greater proportion of patients had excessive DS (EDS) (43 vs. 10%), excessive NSP (ENSP) (27 vs. 9%), or used sleep medication (17 vs. 12%). Difficulties with falling asleep were similar in both groups. In both patients and controls, women experienced more NSP than men. In patients, depressive symptoms accounted for 21% of NSP variance and was the major contributor to the total explained variance (30%). Furthermore, NSP were related to dopamine‐agonist and levodopa dose, whereas DS was related to age, dopamine‐agonist dose, and disease severity. NSP and DS occur frequently in PD, with EDS being reported more commonly than ENSP. No strong relations were found between DS and demographic or clinical variables. The strong relation between NSP and depressive symptoms in PD calls for future studies to explore the nature of this relation. © 2007 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>sleep</term></item><item><term>Parkinson's disease</term></item><item><term>SCOPA‐SLEEP</term></item><item><term>insomnia</term></item><item><term>excessive daytime sleepiness</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Research Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2007-06-12">Received</change><change when="2007-08-14">Registration</change><change when="2008-01">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/BEE00B7711D7D7DF1865090033D443D02661DFA4/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="short">Mov. 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Box 9600, 2300 RC Leiden, The Netherlands</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:MDS.MDS21727.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="0"></count><count type="tableTotal" number="4"></count><count type="referenceTotal" number="42"></count><count type="wordTotal" number="5022"></count></countGroup><titleGroup><title type="main" xml:lang="en">Nighttime sleep problems and daytime sleepiness in Parkinson's disease</title><title type="short" xml:lang="en">Nighttime Sleep Problems and Daytime Sleepiness in PD</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Dagmar</givenNames><familyName>Verbaan</familyName><degrees>MSc</degrees></personName><contactDetails><email>d.verbaan@lumc.nl</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Stephanie M.</givenNames><familyName>van Rooden</familyName><degrees>MSc</degrees></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Martine</givenNames><familyName>Visser</familyName><degrees>PhD</degrees></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Johan</givenNames><familyName>Marinus</familyName><degrees>PhD</degrees></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Jacobus J.</givenNames><familyName>van Hilten</familyName><degrees>MD, PhD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="NL" type="organization"><unparsedAffiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">sleep</keyword><keyword xml:id="kwd2">Parkinson's disease</keyword><keyword xml:id="kwd3">SCOPA‐SLEEP</keyword><keyword xml:id="kwd4">insomnia</keyword><keyword xml:id="kwd5">excessive daytime sleepiness</keyword></keywordGroup><fundingInfo><fundingAgency>Prinses Beatrix Foundation</fundingAgency><fundingNumber>PBF, project no. WAR05‐0120</fundingNumber></fundingInfo><fundingInfo><fundingAgency>Netherlands Organization of Scientific Research</fundingAgency><fundingNumber>NWO, project no. 0940‐33‐021</fundingNumber></fundingInfo><fundingInfo><fundingAgency>van Alkemade‐Keuls Foundation</fundingAgency></fundingInfo><fundingInfo><fundingAgency>Dutch Parkinson's Disease Society</fundingAgency></fundingInfo><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Our objective is to evaluate nighttime sleep problems (NSP) and daytime sleepiness (DS) in patients with Parkinson's disease (PD) compared to controls, and to assess relations with demographic, disease‐related, and clinical characteristics in patients. NSP and DS were evaluated with the SCOPA‐SLEEP questionnaire in PD patients and controls. In patients, other disease‐related and clinical characteristics were also evaluated. Four hundred twenty PD patients [mean (SD) age 61.1 (11.5) years] and 150 controls [mean (SD) age 60.9 (9.9) years] participated in the study. Compared to controls, a significantly greater proportion of patients had excessive DS (EDS) (43 vs. 10%), excessive NSP (ENSP) (27 vs. 9%), or used sleep medication (17 vs. 12%). Difficulties with falling asleep were similar in both groups. In both patients and controls, women experienced more NSP than men. In patients, depressive symptoms accounted for 21% of NSP variance and was the major contributor to the total explained variance (30%). Furthermore, NSP were related to dopamine‐agonist and levodopa dose, whereas DS was related to age, dopamine‐agonist dose, and disease severity. NSP and DS occur frequently in PD, with EDS being reported more commonly than ENSP. No strong relations were found between DS and demographic or clinical variables. The strong relation between NSP and depressive symptoms in PD calls for future studies to explore the nature of this relation. © 2007 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Nighttime sleep problems and daytime sleepiness in Parkinson's disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Nighttime Sleep Problems and Daytime Sleepiness in PD</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Nighttime sleep problems and daytime sleepiness in Parkinson's disease</title></titleInfo><name type="personal"><namePart type="given">Dagmar</namePart><namePart type="family">Verbaan</namePart><namePart type="termsOfAddress">MSc</namePart><affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</affiliation><description>Correspondence: Department of Neurology, K5Q‐92, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Stephanie M.</namePart><namePart type="family">van Rooden</namePart><namePart type="termsOfAddress">MSc</namePart><affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Martine</namePart><namePart type="family">Visser</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Johan</namePart><namePart type="family">Marinus</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jacobus J.</namePart><namePart type="family">van Hilten</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2008-01</dateIssued><dateCaptured encoding="w3cdtf">2007-06-12</dateCaptured><dateValid encoding="w3cdtf">2007-08-14</dateValid><copyrightDate encoding="w3cdtf">2008</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">4</extent><extent unit="references">42</extent><extent unit="words">5022</extent></physicalDescription><abstract lang="en">Our objective is to evaluate nighttime sleep problems (NSP) and daytime sleepiness (DS) in patients with Parkinson's disease (PD) compared to controls, and to assess relations with demographic, disease‐related, and clinical characteristics in patients. NSP and DS were evaluated with the SCOPA‐SLEEP questionnaire in PD patients and controls. In patients, other disease‐related and clinical characteristics were also evaluated. Four hundred twenty PD patients [mean (SD) age 61.1 (11.5) years] and 150 controls [mean (SD) age 60.9 (9.9) years] participated in the study. Compared to controls, a significantly greater proportion of patients had excessive DS (EDS) (43 vs. 10%), excessive NSP (ENSP) (27 vs. 9%), or used sleep medication (17 vs. 12%). Difficulties with falling asleep were similar in both groups. In both patients and controls, women experienced more NSP than men. In patients, depressive symptoms accounted for 21% of NSP variance and was the major contributor to the total explained variance (30%). Furthermore, NSP were related to dopamine‐agonist and levodopa dose, whereas DS was related to age, dopamine‐agonist dose, and disease severity. NSP and DS occur frequently in PD, with EDS being reported more commonly than ENSP. No strong relations were found between DS and demographic or clinical variables. The strong relation between NSP and depressive symptoms in PD calls for future studies to explore the nature of this relation. © 2007 Movement Disorder Society</abstract><note type="funding">Prinses Beatrix Foundation - No. PBF, project no. WAR05‐0120; </note><note type="funding">Netherlands Organization of Scientific Research - No. NWO, project no. 0940‐33‐021; </note><note type="funding">van Alkemade‐Keuls Foundation</note><note type="funding">Dutch Parkinson's Disease Society</note><subject lang="en"><genre>Keywords</genre><topic>sleep</topic><topic>Parkinson's disease</topic><topic>SCOPA‐SLEEP</topic><topic>insomnia</topic><topic>excessive daytime sleepiness</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>23</number></detail><detail type="issue"><caption>no.</caption><number>1</number></detail><extent unit="pages"><start>35</start><end>41</end><total>7</total></extent></part></relatedItem><identifier type="istex">BEE00B7711D7D7DF1865090033D443D02661DFA4</identifier><identifier type="DOI">10.1002/mds.21727</identifier><identifier type="ArticleID">MDS21727</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2007 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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