Clinical and economic analysis of spa therapy in Parkinson's disease
Identifieur interne : 000716 ( Istex/Corpus ); précédent : 000715; suivant : 000717Clinical and economic analysis of spa therapy in Parkinson's disease
Auteurs : Christine Brefel-Courbon ; Karine Desboeuf ; Claire Thalamas ; Monique Galitzky ; Jean-Michel Senard ; Olivier Rascol ; Jean-Louis MontastrucSource :
- Movement Disorders [ 0885-3185 ] ; 2003-05.
English descriptors
Abstract
The effectiveness of spa therapy in the management of patients with Parkinson's disease (PD) has never been evaluated. This is assessed in this pilot study. A prospective, randomized, cross‐over, controlled study was conducted in 31 PD patients who underwent a 20‐week spa period, including spa therapy for 3 weeks, and a 20‐week non‐spa period. Effectiveness was assessed using quality of life scales (PDQ‐39 and SF‐36), motor scale (UPDRS) and psychological questionnaire (GHQ‐28), at baseline and at 4 (T4) and at 20 weeks (T20). Direct medical costs (radiological and laboratory tests, physician fees, drug therapy, and ancillary care) were recorded over each 20‐week period. At T4, spa therapy improved significantly several dimensions of PDQ‐39 and SF‐36, part IV of the UPDRS, and GHQ‐28. At T20, no difference in any parameter was found. The mean direct medical cost over 20 weeks (€1,328 ± 167; £776 ± 97 per patient) in the spa period was slightly but significantly reduced in comparison with that of the non‐spa period (€1380 ± 523; £807 ± 306 per patient). This cost‐effectiveness analysis suggests that spa therapy is more effective and less expensive than conventional treatment alone and could be beneficial in the management of PD.
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DOI: 10.1002/mds.10404
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ISTEX:DFE14B63358F5167B0F176C4E87ED98845C77D87Le document en format XML
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This is assessed in this pilot study. A prospective, randomized, cross‐over, controlled study was conducted in 31 PD patients who underwent a 20‐week spa period, including spa therapy for 3 weeks, and a 20‐week non‐spa period. Effectiveness was assessed using quality of life scales (PDQ‐39 and SF‐36), motor scale (UPDRS) and psychological questionnaire (GHQ‐28), at baseline and at 4 (T4) and at 20 weeks (T20). Direct medical costs (radiological and laboratory tests, physician fees, drug therapy, and ancillary care) were recorded over each 20‐week period. At T4, spa therapy improved significantly several dimensions of PDQ‐39 and SF‐36, part IV of the UPDRS, and GHQ‐28. At T20, no difference in any parameter was found. The mean direct medical cost over 20 weeks (€1,328 ± 167; £776 ± 97 per patient) in the spa period was slightly but significantly reduced in comparison with that of the non‐spa period (€1380 ± 523; £807 ± 306 per patient). 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type="first">Jean‐Michel</forename><surname>Senard</surname><roleName type="degree">MD, PhD</roleName></persName><affiliation>Service de Pharmacologie Clinique and Service d'Hydrologie et de Climatologie Médicales, Laboratoire de Médecine Thermale, University Hospital, Toulouse, France</affiliation></author><author><persName><forename type="first">Olivier</forename><surname>Rascol</surname><roleName type="degree">MD, PhD</roleName></persName><affiliation>Service de Pharmacologie Clinique and Service d'Hydrologie et de Climatologie Médicales, Laboratoire de Médecine Thermale, University Hospital, Toulouse, France</affiliation><affiliation>Centre d'Investigation Clinique, Purpan Hospital, Toulouse, France</affiliation></author><author><persName><forename type="first">Jean‐Louis</forename><surname>Montastruc</surname><roleName type="degree">MD, PhD</roleName></persName><affiliation>Service de Pharmacologie Clinique and Service d'Hydrologie et de Climatologie Médicales, Laboratoire de 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creatorRole="author" affiliationRef="#af2"><personName><givenNames>Claire</givenNames><familyName>Thalamas</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Monique</givenNames><familyName>Galitzky</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Jean‐Michel</givenNames><familyName>Senard</familyName><degrees>MD, PhD</degrees></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af1 #af2"><personName><givenNames>Olivier</givenNames><familyName>Rascol</familyName><degrees>MD, PhD</degrees></personName></creator><creator xml:id="au7" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Jean‐Louis</givenNames><familyName>Montastruc</familyName><degrees>MD, PhD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="FR" type="organization"><unparsedAffiliation>Service de Pharmacologie Clinique and Service d'Hydrologie et de Climatologie Médicales, Laboratoire de Médecine Thermale, University Hospital, Toulouse, France</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="FR" type="organization"><unparsedAffiliation>Centre d'Investigation Clinique, Purpan Hospital, Toulouse, France</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">Parkinson's disease</keyword><keyword xml:id="kwd2">spa therapy</keyword><keyword xml:id="kwd3">cost effectiveness</keyword><keyword xml:id="kwd4">quality of life</keyword><keyword xml:id="kwd5">clinical trial</keyword></keywordGroup><fundingInfo><fundingAgency>Ussat Les Bains</fundingAgency></fundingInfo><fundingInfo><fundingAgency>regional council of Haute Garonne</fundingAgency></fundingInfo><fundingInfo><fundingAgency>department council of Ariege</fundingAgency></fundingInfo><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>The effectiveness of spa therapy in the management of patients with Parkinson's disease (PD) has never been evaluated. This is assessed in this pilot study. A prospective, randomized, cross‐over, controlled study was conducted in 31 PD patients who underwent a 20‐week spa period, including spa therapy for 3 weeks, and a 20‐week non‐spa period. Effectiveness was assessed using quality of life scales (PDQ‐39 and SF‐36), motor scale (UPDRS) and psychological questionnaire (GHQ‐28), at baseline and at 4 (T4) and at 20 weeks (T20). Direct medical costs (radiological and laboratory tests, physician fees, drug therapy, and ancillary care) were recorded over each 20‐week period. At T4, spa therapy improved significantly several dimensions of PDQ‐39 and SF‐36, part IV of the UPDRS, and GHQ‐28. At T20, no difference in any parameter was found. The mean direct medical cost over 20 weeks (€1,328 ± 167; £776 ± 97 per patient) in the spa period was slightly but significantly reduced in comparison with that of the non‐spa period (€1380 ± 523; £807 ± 306 per patient). This cost‐effectiveness analysis suggests that spa therapy is more effective and less expensive than conventional treatment alone and could be beneficial in the management of PD.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Clinical and economic analysis of spa therapy in Parkinson's disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Spa Therapy in Parkinson's Disease</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Clinical and economic analysis of spa therapy in Parkinson's disease</title></titleInfo><name type="personal"><namePart type="given">Christine</namePart><namePart type="family">Brefel‐Courbon</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Service de Pharmacologie Clinique and Service d'Hydrologie et de Climatologie Médicales, Laboratoire de Médecine Thermale, University Hospital, Toulouse, France</affiliation><description>Correspondence: Service de Pharmacologie Médicale et Clinique, Faculté de Medecine, 37 allées Jules Guesde, 31073 Toulouse Cedex, France</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Karine</namePart><namePart type="family">Desboeuf</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Service de Pharmacologie Clinique and Service d'Hydrologie et de Climatologie Médicales, Laboratoire de Médecine Thermale, University Hospital, Toulouse, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Claire</namePart><namePart type="family">Thalamas</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Centre d'Investigation Clinique, Purpan Hospital, Toulouse, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Monique</namePart><namePart type="family">Galitzky</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Centre d'Investigation Clinique, Purpan Hospital, Toulouse, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jean‐Michel</namePart><namePart type="family">Senard</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Service de Pharmacologie Clinique and Service d'Hydrologie et de Climatologie Médicales, Laboratoire de Médecine Thermale, University Hospital, Toulouse, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Olivier</namePart><namePart type="family">Rascol</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Service de Pharmacologie Clinique and Service d'Hydrologie et de Climatologie Médicales, Laboratoire de Médecine Thermale, University Hospital, Toulouse, France</affiliation><affiliation>Centre d'Investigation Clinique, Purpan Hospital, Toulouse, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jean‐Louis</namePart><namePart type="family">Montastruc</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Service de Pharmacologie Clinique and Service d'Hydrologie et de Climatologie Médicales, Laboratoire de Médecine Thermale, University Hospital, Toulouse, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">New York</placeTerm></place><dateIssued encoding="w3cdtf">2003-05</dateIssued><dateCaptured encoding="w3cdtf">2002-03-25</dateCaptured><dateValid encoding="w3cdtf">2002-10-18</dateValid><copyrightDate encoding="w3cdtf">2003</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="tables">5</extent><extent unit="references">23</extent><extent unit="words">4365</extent></physicalDescription><abstract lang="en">The effectiveness of spa therapy in the management of patients with Parkinson's disease (PD) has never been evaluated. This is assessed in this pilot study. A prospective, randomized, cross‐over, controlled study was conducted in 31 PD patients who underwent a 20‐week spa period, including spa therapy for 3 weeks, and a 20‐week non‐spa period. Effectiveness was assessed using quality of life scales (PDQ‐39 and SF‐36), motor scale (UPDRS) and psychological questionnaire (GHQ‐28), at baseline and at 4 (T4) and at 20 weeks (T20). Direct medical costs (radiological and laboratory tests, physician fees, drug therapy, and ancillary care) were recorded over each 20‐week period. At T4, spa therapy improved significantly several dimensions of PDQ‐39 and SF‐36, part IV of the UPDRS, and GHQ‐28. At T20, no difference in any parameter was found. The mean direct medical cost over 20 weeks (€1,328 ± 167; £776 ± 97 per patient) in the spa period was slightly but significantly reduced in comparison with that of the non‐spa period (€1380 ± 523; £807 ± 306 per patient). This cost‐effectiveness analysis suggests that spa therapy is more effective and less expensive than conventional treatment alone and could be beneficial in the management of PD.</abstract><note type="funding">Ussat Les Bains</note><note type="funding">regional council of Haute Garonne</note><note type="funding">department council of Ariege</note><subject lang="en"><genre>Keywords</genre><topic>Parkinson's disease</topic><topic>spa therapy</topic><topic>cost effectiveness</topic><topic>quality of life</topic><topic>clinical trial</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><detail type="issue"><caption>no.</caption><number>5</number></detail><extent unit="pages"><start>578</start><end>584</end><total>6</total></extent></part></relatedItem><identifier type="istex">DFE14B63358F5167B0F176C4E87ED98845C77D87</identifier><identifier type="DOI">10.1002/mds.10404</identifier><identifier type="ArticleID">MDS10404</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2003 Movement Disorders Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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