Restless legs syndrome in Parkinson's disease and other neurodegenerative diseases of the central nervous system
Identifieur interne : 000711 ( Istex/Corpus ); précédent : 000710; suivant : 000712Restless legs syndrome in Parkinson's disease and other neurodegenerative diseases of the central nervous system
Auteurs : Alex Iranzo ; Cynthia L. Comella ; Joan Santamaria ; Wolfgang OertelSource :
- Movement Disorders [ 0885-3185 ] ; 2007.
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- KwdEn :
Abstract
The pathophysiology of restless legs syndrome (RLS) is associated with central dopaminergic system dysfunction leading to speculations that RLS may be common in those neurodegenerative diseases with dopaminergic cell loss. However, since RLS is a very common condition, the co‐occurrence with less frequent disorders such as the neurodegenerative diseases might be a matter of chance. Currently, no data suggests that patients with sporadic and familial RLS are at increased risk for developing a neurodegenerative disease. In particular, whether RLS is associated with Parkinson's disease has not been established. Only a few studies have directly addressed this issue, and these have methodological limitations yielding conflicting results. Few studies have assessed the frequency of RLS in other neurodegenerative disorders. In several autosomal dominant spinocerebellar ataxias, particularly in Machado‐Joseph disease, a higher frequency of RLS is reported than could be accounted for in the general population. Two anecdotal publications have reported the presence of RLS in patients with Huntington's disease and hereditary spastic paraparesis. There are no studies that have examined the association between RLS and other neurodegenerative diseases, such as Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, multiple system atrophy, progressive supranuclear palsy, and corticobasal degeneration. © 2007 Movement Disorder Society
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DOI: 10.1002/mds.21600
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ISTEX:41D79A3AC267341773474CDCD01DC4032FBFE275Le document en format XML
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However, since RLS is a very common condition, the co‐occurrence with less frequent disorders such as the neurodegenerative diseases might be a matter of chance. Currently, no data suggests that patients with sporadic and familial RLS are at increased risk for developing a neurodegenerative disease. In particular, whether RLS is associated with Parkinson's disease has not been established. Only a few studies have directly addressed this issue, and these have methodological limitations yielding conflicting results. Few studies have assessed the frequency of RLS in other neurodegenerative disorders. In several autosomal dominant spinocerebellar ataxias, particularly in Machado‐Joseph disease, a higher frequency of RLS is reported than could be accounted for in the general population. Two anecdotal publications have reported the presence of RLS in patients with Huntington's disease and hereditary spastic paraparesis. There are no studies that have examined the association between RLS and other neurodegenerative diseases, such as Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, multiple system atrophy, progressive supranuclear palsy, and corticobasal degeneration. © 2007 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Alex Iranzo MD</name><affiliations><json:string>Neurology Service, Hospital Clínic and Institut D'Investigació Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain</json:string></affiliations></json:item><json:item><name>Cynthia L. 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number="5695"></count></countGroup><titleGroup><title type="main" xml:lang="en">Restless legs syndrome in Parkinson's disease and other neurodegenerative diseases of the central nervous system</title><title type="short" xml:lang="en">RLS in PD and Other Neurodegenerative Diseases</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Alex</givenNames><familyName>Iranzo</familyName><degrees>MD</degrees></personName><contactDetails><email>airanzo@clinic.ub.es</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Cynthia L.</givenNames><familyName>Comella</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Joan</givenNames><familyName>Santamaria</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au4" creatorRole="author" 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However, since RLS is a very common condition, the co‐occurrence with less frequent disorders such as the neurodegenerative diseases might be a matter of chance. Currently, no data suggests that patients with sporadic and familial RLS are at increased risk for developing a neurodegenerative disease. In particular, whether RLS is associated with Parkinson's disease has not been established. Only a few studies have directly addressed this issue, and these have methodological limitations yielding conflicting results. Few studies have assessed the frequency of RLS in other neurodegenerative disorders. In several autosomal dominant spinocerebellar ataxias, particularly in Machado‐Joseph disease, a higher frequency of RLS is reported than could be accounted for in the general population. Two anecdotal publications have reported the presence of RLS in patients with Huntington's disease and hereditary spastic paraparesis. There are no studies that have examined the association between RLS and other neurodegenerative diseases, such as Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, multiple system atrophy, progressive supranuclear palsy, and corticobasal degeneration. © 2007 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Restless legs syndrome in Parkinson's disease and other neurodegenerative diseases of the central nervous system</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>RLS in PD and Other Neurodegenerative Diseases</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Restless legs syndrome in Parkinson's disease and other neurodegenerative diseases of the central nervous system</title></titleInfo><name type="personal"><namePart type="given">Alex</namePart><namePart type="family">Iranzo</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Neurology Service, Hospital Clínic and Institut D'Investigació Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain</affiliation><description>Correspondence: Neurology Service, Hospital Clinic de Barcelona, C/Villarroel 170, Barcelona 08036, Spain</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Cynthia L.</namePart><namePart type="family">Comella</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences, Rush University, Medical Center, Chicago, Illinois, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Joan</namePart><namePart type="family">Santamaria</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Neurology Service, Hospital Clínic and Institut D'Investigació Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Wolfgang</namePart><namePart type="family">Oertel</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Center for Nervous Diseases, Philipps University of Marburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">reviewArticle</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2007</dateIssued><dateCaptured encoding="w3cdtf">2007-01-07</dateCaptured><dateValid encoding="w3cdtf">2007-04-24</dateValid><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">2</extent><extent unit="references">60</extent><extent unit="words">5695</extent></physicalDescription><abstract lang="en">The pathophysiology of restless legs syndrome (RLS) is associated with central dopaminergic system dysfunction leading to speculations that RLS may be common in those neurodegenerative diseases with dopaminergic cell loss. However, since RLS is a very common condition, the co‐occurrence with less frequent disorders such as the neurodegenerative diseases might be a matter of chance. Currently, no data suggests that patients with sporadic and familial RLS are at increased risk for developing a neurodegenerative disease. In particular, whether RLS is associated with Parkinson's disease has not been established. Only a few studies have directly addressed this issue, and these have methodological limitations yielding conflicting results. Few studies have assessed the frequency of RLS in other neurodegenerative disorders. In several autosomal dominant spinocerebellar ataxias, particularly in Machado‐Joseph disease, a higher frequency of RLS is reported than could be accounted for in the general population. Two anecdotal publications have reported the presence of RLS in patients with Huntington's disease and hereditary spastic paraparesis. There are no studies that have examined the association between RLS and other neurodegenerative diseases, such as Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, multiple system atrophy, progressive supranuclear palsy, and corticobasal degeneration. © 2007 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>restless legs syndrome</topic><topic>neurodegenerative diseases</topic><topic>dopaminergic system</topic><topic>Parkinson's disease</topic><topic>autosomal dominant spinocerebellar ataxias</topic><topic>Machado–Joseph disease</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><name type="personal"><namePart type="given">Claudia</namePart><namePart type="family">Trenkwalder</namePart></name><name type="personal"><namePart type="given">Wolfgang</namePart><namePart type="family">Oertel</namePart></name><name type="personal"><namePart type="given">Richard</namePart><namePart type="family">Allen</namePart></name><name type="personal"><namePart type="given">Diego</namePart><namePart type="family">Garcia‐Borreguero</namePart></name><subject><genre>article category</genre><topic>Review</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><detail type="issue"><caption>no.</caption><number>S18</number></detail><detail type="supplement"><caption>Suppl. no.</caption><number>S18</number></detail><extent unit="pages"><start>S424</start><end>S430</end><total>7</total></extent></part></relatedItem><identifier type="istex">41D79A3AC267341773474CDCD01DC4032FBFE275</identifier><identifier type="DOI">10.1002/mds.21600</identifier><identifier type="ArticleID">MDS21600</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2007 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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