Evidence for shoulder girdle dystonia in selected patients with cervical disc prolapse
Identifieur interne : 000518 ( Istex/Corpus ); précédent : 000517; suivant : 000519Evidence for shoulder girdle dystonia in selected patients with cervical disc prolapse
Auteurs : Georg Becker ; Daniela Berg ; Niels Kruse ; Ute Schröder ; Monika Warmuth-Metz ; Peter Rieckmann ; Markus Naumann ; Karlheinz ReinersSource :
- Movement Disorders [ 0885-3185 ] ; 2002-07.
English descriptors
- KwdEn :
Abstract
Some patients with cervical disc herniation suffer from persistent nuchal pain and muscle spasms after decompressive surgery despite the lack of clinical and radiological signs for actual spinal root compression. Sonographic examination of the brain in some of these patients showed increased echogenicity of the lentiform nuclei as described in patients with idiopathic dystonia. This has been linked to an altered Menkes protein level and copper metabolism. We suggest a relationship between persistent nuchal pain after adequate cervical disc surgery and dystonic movement disorders. Thirteen patients with persistent nonradicular nuchal pain after at least one cervical disc surgery and without evidence of continuing spinal root compression and 13 age‐matched controls were included. All patients had a complete neurological examination, ultrasound, and MRI scan of the brain. In addition, Menkes protein mRNA levels of leucocytes were analyzed in patients and controls. All patients with persistent nuchal pain exhibited a constant tonic unilateral shoulder elevation associated with an ipsilateral hypertrophy of the trapezius muscle. Ultrasound examination showed an increased echogenicity of the lentiform nucleus in one patient unilaterally and in 10 patients bilaterally but in none of the controls. On MRI the T2‐values of the lentiform nuclei were found to be higher in patients exhibiting a hyperechogenicity of the lentiform nuclei compared to controls (P = 0.01). In addition, Menkes protein mRNA levels were decreased in patients with cervical disc herniation (P = 0.03). Clinical, neuroimaging, and biochemical findings of this selected patient sample with chronic nuchal pain and muscle spasms after cervical disc surgery resemble alterations in patients with idiopathic cervical dystonia. This suggests a link between both disorders. A peripheral trauma to the nerve roots may precipitate dystonic movements in susceptible patients and chronic dystonic muscle contraction would account for the persistent nuchal pain. © 2002 Movement Disorder Society
Url:
DOI: 10.1002/mds.10132
Links to Exploration step
ISTEX:CE5656C05B381CBFC382FB9BA4F0D9BEF0CE8830Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Evidence for shoulder girdle dystonia in selected patients with cervical disc prolapse</title><author><name sortKey="Becker, Georg" sort="Becker, Georg" uniqKey="Becker G" first="Georg" last="Becker">Georg Becker</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Kruse, Niels" sort="Kruse, Niels" uniqKey="Kruse N" first="Niels" last="Kruse">Niels Kruse</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Schroder, Ute" sort="Schroder, Ute" uniqKey="Schroder U" first="Ute" last="Schröder">Ute Schröder</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Warmuth Etz, Monika" sort="Warmuth Etz, Monika" uniqKey="Warmuth Etz M" first="Monika" last="Warmuth-Metz">Monika Warmuth-Metz</name><affiliation><mods:affiliation>Division of Neuroradiology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Rieckmann, Peter" sort="Rieckmann, Peter" uniqKey="Rieckmann P" first="Peter" last="Rieckmann">Peter Rieckmann</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Naumann, Markus" sort="Naumann, Markus" uniqKey="Naumann M" first="Markus" last="Naumann">Markus Naumann</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Reiners, Karlheinz" sort="Reiners, Karlheinz" uniqKey="Reiners K" first="Karlheinz" last="Reiners">Karlheinz Reiners</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:CE5656C05B381CBFC382FB9BA4F0D9BEF0CE8830</idno><date when="2002" year="2002">2002</date><idno type="doi">10.1002/mds.10132</idno><idno type="url">https://api.istex.fr/document/CE5656C05B381CBFC382FB9BA4F0D9BEF0CE8830/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000518</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Evidence for shoulder girdle dystonia in selected patients with cervical disc prolapse</title><author><name sortKey="Becker, Georg" sort="Becker, Georg" uniqKey="Becker G" first="Georg" last="Becker">Georg Becker</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Kruse, Niels" sort="Kruse, Niels" uniqKey="Kruse N" first="Niels" last="Kruse">Niels Kruse</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Schroder, Ute" sort="Schroder, Ute" uniqKey="Schroder U" first="Ute" last="Schröder">Ute Schröder</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Warmuth Etz, Monika" sort="Warmuth Etz, Monika" uniqKey="Warmuth Etz M" first="Monika" last="Warmuth-Metz">Monika Warmuth-Metz</name><affiliation><mods:affiliation>Division of Neuroradiology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Rieckmann, Peter" sort="Rieckmann, Peter" uniqKey="Rieckmann P" first="Peter" last="Rieckmann">Peter Rieckmann</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Naumann, Markus" sort="Naumann, Markus" uniqKey="Naumann M" first="Markus" last="Naumann">Markus Naumann</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Reiners, Karlheinz" sort="Reiners, Karlheinz" uniqKey="Reiners K" first="Karlheinz" last="Reiners">Karlheinz Reiners</name><affiliation><mods:affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>New York</pubPlace><date type="published" when="2002-07">2002-07</date><biblScope unit="vol">17</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="710">710</biblScope><biblScope unit="page" to="716">716</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">CE5656C05B381CBFC382FB9BA4F0D9BEF0CE8830</idno><idno type="DOI">10.1002/mds.10132</idno><idno type="ArticleID">MDS10132</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>cervical disc herniation</term><term>dystonia</term><term>nuchal pain</term><term>spinal root compression</term><term>transcranial sonography</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Some patients with cervical disc herniation suffer from persistent nuchal pain and muscle spasms after decompressive surgery despite the lack of clinical and radiological signs for actual spinal root compression. Sonographic examination of the brain in some of these patients showed increased echogenicity of the lentiform nuclei as described in patients with idiopathic dystonia. This has been linked to an altered Menkes protein level and copper metabolism. We suggest a relationship between persistent nuchal pain after adequate cervical disc surgery and dystonic movement disorders. Thirteen patients with persistent nonradicular nuchal pain after at least one cervical disc surgery and without evidence of continuing spinal root compression and 13 age‐matched controls were included. All patients had a complete neurological examination, ultrasound, and MRI scan of the brain. In addition, Menkes protein mRNA levels of leucocytes were analyzed in patients and controls. All patients with persistent nuchal pain exhibited a constant tonic unilateral shoulder elevation associated with an ipsilateral hypertrophy of the trapezius muscle. Ultrasound examination showed an increased echogenicity of the lentiform nucleus in one patient unilaterally and in 10 patients bilaterally but in none of the controls. On MRI the T2‐values of the lentiform nuclei were found to be higher in patients exhibiting a hyperechogenicity of the lentiform nuclei compared to controls (P = 0.01). In addition, Menkes protein mRNA levels were decreased in patients with cervical disc herniation (P = 0.03). Clinical, neuroimaging, and biochemical findings of this selected patient sample with chronic nuchal pain and muscle spasms after cervical disc surgery resemble alterations in patients with idiopathic cervical dystonia. This suggests a link between both disorders. A peripheral trauma to the nerve roots may precipitate dystonic movements in susceptible patients and chronic dystonic muscle contraction would account for the persistent nuchal pain. © 2002 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Georg Becker MD</name><affiliations><json:string>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</json:string></affiliations></json:item><json:item><name>Daniela Berg MD</name><affiliations><json:string>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</json:string></affiliations></json:item><json:item><name>Niels Kruse PhD</name><affiliations><json:string>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</json:string></affiliations></json:item><json:item><name>Ute Schröder</name><affiliations><json:string>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</json:string></affiliations></json:item><json:item><name>Monika Warmuth‐Metz MD</name><affiliations><json:string>Division of Neuroradiology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</json:string></affiliations></json:item><json:item><name>Peter Rieckmann MD</name><affiliations><json:string>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</json:string></affiliations></json:item><json:item><name>Markus Naumann MD</name><affiliations><json:string>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</json:string></affiliations></json:item><json:item><name>Karlheinz Reiners MD</name><affiliations><json:string>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>cervical disc herniation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>spinal root compression</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>nuchal pain</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>dystonia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>transcranial sonography</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Some patients with cervical disc herniation suffer from persistent nuchal pain and muscle spasms after decompressive surgery despite the lack of clinical and radiological signs for actual spinal root compression. Sonographic examination of the brain in some of these patients showed increased echogenicity of the lentiform nuclei as described in patients with idiopathic dystonia. This has been linked to an altered Menkes protein level and copper metabolism. We suggest a relationship between persistent nuchal pain after adequate cervical disc surgery and dystonic movement disorders. Thirteen patients with persistent nonradicular nuchal pain after at least one cervical disc surgery and without evidence of continuing spinal root compression and 13 age‐matched controls were included. All patients had a complete neurological examination, ultrasound, and MRI scan of the brain. In addition, Menkes protein mRNA levels of leucocytes were analyzed in patients and controls. All patients with persistent nuchal pain exhibited a constant tonic unilateral shoulder elevation associated with an ipsilateral hypertrophy of the trapezius muscle. Ultrasound examination showed an increased echogenicity of the lentiform nucleus in one patient unilaterally and in 10 patients bilaterally but in none of the controls. On MRI the T2‐values of the lentiform nuclei were found to be higher in patients exhibiting a hyperechogenicity of the lentiform nuclei compared to controls (P = 0.01). In addition, Menkes protein mRNA levels were decreased in patients with cervical disc herniation (P = 0.03). Clinical, neuroimaging, and biochemical findings of this selected patient sample with chronic nuchal pain and muscle spasms after cervical disc surgery resemble alterations in patients with idiopathic cervical dystonia. This suggests a link between both disorders. A peripheral trauma to the nerve roots may precipitate dystonic movements in susceptible patients and chronic dystonic muscle contraction would account for the persistent nuchal pain. © 2002 Movement Disorder Society</abstract><qualityIndicators><score>7.511</score><pdfVersion>1.4</pdfVersion><pdfPageSize>612 x 792 pts (letter)</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>2070</abstractCharCount><pdfWordCount>4011</pdfWordCount><pdfCharCount>25522</pdfCharCount><pdfPageCount>7</pdfPageCount><abstractWordCount>299</abstractWordCount></qualityIndicators><title>Evidence for shoulder girdle dystonia in selected patients with cervical disc prolapse</title><genre><json:string>Serial article</json:string></genre><host><volume>17</volume><pages><total>7</total><last>716</last><first>710</first></pages><issn><json:string>0885-3185</json:string></issn><issue>4</issue><subject><json:item><value>Research Article</value></json:item></subject><genre></genre><language><json:string>unknown</json:string></language><title>Movement Disorders</title><doi><json:string>10.1002/(ISSN)1531-8257</json:string></doi></host><publicationDate>2002</publicationDate><copyrightDate>2002</copyrightDate><doi><json:string>10.1002/mds.10132</json:string></doi><id>CE5656C05B381CBFC382FB9BA4F0D9BEF0CE8830</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/CE5656C05B381CBFC382FB9BA4F0D9BEF0CE8830/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/CE5656C05B381CBFC382FB9BA4F0D9BEF0CE8830/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/CE5656C05B381CBFC382FB9BA4F0D9BEF0CE8830/fulltext/tei"><teiHeader type="text"><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Evidence for shoulder girdle dystonia in selected patients with cervical disc prolapse</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>New York</pubPlace><availability><p>Wiley Subscription Services, Inc., A Wiley Company</p></availability><date>2002</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Evidence for shoulder girdle dystonia in selected patients with cervical disc prolapse</title><author><persName><forename type="first">Georg</forename><surname>Becker</surname><roleName type="degree">MD</roleName></persName><note type="correspondence"><p>Correspondence: Department of Neurology, Universität des Saarlandes, Gebäude 90, 66421 Homburg/Saar, Germany</p></note><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation></author><author><persName><forename type="first">Daniela</forename><surname>Berg</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation></author><author><persName><forename type="first">Niels</forename><surname>Kruse</surname><roleName type="degree">PhD</roleName></persName><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation></author><author><persName><forename type="first">Ute</forename><surname>Schröder</surname></persName><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation></author><author><persName><forename type="first">Monika</forename><surname>Warmuth‐Metz</surname><roleName type="degree">MD</roleName></persName><affiliation>Division of Neuroradiology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation></author><author><persName><forename type="first">Peter</forename><surname>Rieckmann</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation></author><author><persName><forename type="first">Markus</forename><surname>Naumann</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation></author><author><persName><forename type="first">Karlheinz</forename><surname>Reiners</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation></author></analytic><monogr><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>New York</pubPlace><date type="published" when="2002-07"></date><biblScope unit="vol">17</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="710">710</biblScope><biblScope unit="page" to="716">716</biblScope></imprint></monogr><idno type="istex">CE5656C05B381CBFC382FB9BA4F0D9BEF0CE8830</idno><idno type="DOI">10.1002/mds.10132</idno><idno type="ArticleID">MDS10132</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2002</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Some patients with cervical disc herniation suffer from persistent nuchal pain and muscle spasms after decompressive surgery despite the lack of clinical and radiological signs for actual spinal root compression. Sonographic examination of the brain in some of these patients showed increased echogenicity of the lentiform nuclei as described in patients with idiopathic dystonia. This has been linked to an altered Menkes protein level and copper metabolism. We suggest a relationship between persistent nuchal pain after adequate cervical disc surgery and dystonic movement disorders. Thirteen patients with persistent nonradicular nuchal pain after at least one cervical disc surgery and without evidence of continuing spinal root compression and 13 age‐matched controls were included. All patients had a complete neurological examination, ultrasound, and MRI scan of the brain. In addition, Menkes protein mRNA levels of leucocytes were analyzed in patients and controls. All patients with persistent nuchal pain exhibited a constant tonic unilateral shoulder elevation associated with an ipsilateral hypertrophy of the trapezius muscle. Ultrasound examination showed an increased echogenicity of the lentiform nucleus in one patient unilaterally and in 10 patients bilaterally but in none of the controls. On MRI the T2‐values of the lentiform nuclei were found to be higher in patients exhibiting a hyperechogenicity of the lentiform nuclei compared to controls (P = 0.01). In addition, Menkes protein mRNA levels were decreased in patients with cervical disc herniation (P = 0.03). Clinical, neuroimaging, and biochemical findings of this selected patient sample with chronic nuchal pain and muscle spasms after cervical disc surgery resemble alterations in patients with idiopathic cervical dystonia. This suggests a link between both disorders. A peripheral trauma to the nerve roots may precipitate dystonic movements in susceptible patients and chronic dystonic muscle contraction would account for the persistent nuchal pain. © 2002 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>cervical disc herniation</term></item><item><term>spinal root compression</term></item><item><term>nuchal pain</term></item><item><term>dystonia</term></item><item><term>transcranial sonography</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Research Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2001-04-18">Received</change><change when="2001-12-17">Registration</change><change when="2002-07">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/CE5656C05B381CBFC382FB9BA4F0D9BEF0CE8830/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>New York</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="short">Mov. Disord.</title></titleGroup></publicationMeta><publicationMeta level="part" position="40"><doi origin="wiley" registered="yes">10.1002/mds.v17:4</doi><numberingGroup><numbering type="journalVolume" number="17">17</numbering><numbering type="journalIssue">4</numbering></numberingGroup><coverDate startDate="2002-07">July/August 2002</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="110" status="forIssue"><doi origin="wiley" registered="yes">10.1002/mds.10132</doi><idGroup><id type="unit" value="MDS10132"></id></idGroup><countGroup><count type="pageTotal" number="7"></count></countGroup><titleGroup><title type="articleCategory">Research Article</title><title type="tocHeading1">Research Articles</title></titleGroup><copyright ownership="thirdParty">Copyright © 2002 Movement Disorders Society</copyright><eventGroup><event type="manuscriptReceived" date="2001-04-18"></event><event type="manuscriptRevised" date="2001-09-07"></event><event type="manuscriptAccepted" date="2001-12-17"></event><event type="firstOnline" date="2002-04-10"></event><event type="publishedOnlineFinalForm" date="2002-07-22"></event><event type="publishedOnlineAcceptedOrEarlyUnpaginated" date="2002-04-10"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.4.7 mode:FullText source:FullText result:FullText" date="2011-02-24"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-02"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-31"></event></eventGroup><numberingGroup><numbering type="pageFirst">710</numbering><numbering type="pageLast">716</numbering></numberingGroup><correspondenceTo>Department of Neurology, Universität des Saarlandes, Gebäude 90, 66421 Homburg/Saar, Germany</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:MDS.MDS10132.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="3"></count><count type="tableTotal" number="1"></count><count type="referenceTotal" number="21"></count><count type="wordTotal" number="3854"></count></countGroup><titleGroup><title type="main" xml:lang="en">Evidence for shoulder girdle dystonia in selected patients with cervical disc prolapse</title><title type="short" xml:lang="en">Dystonia and Cervical Disc Prolapse</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Georg</givenNames><familyName>Becker</familyName><degrees>MD</degrees></personName><contactDetails><email normalForm="georg.becker@uniklinik-saarland.de">georg.becker@uniklinik‐saarland.de</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Daniela</givenNames><familyName>Berg</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Niels</givenNames><familyName>Kruse</familyName><degrees>PhD</degrees></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Ute</givenNames><familyName>Schröder</familyName></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Monika</givenNames><familyName>Warmuth‐Metz</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Peter</givenNames><familyName>Rieckmann</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au7" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Markus</givenNames><familyName>Naumann</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au8" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Karlheinz</givenNames><familyName>Reiners</familyName><degrees>MD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="DE" type="organization"><unparsedAffiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="DE" type="organization"><unparsedAffiliation>Division of Neuroradiology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">cervical disc herniation</keyword><keyword xml:id="kwd2">spinal root compression</keyword><keyword xml:id="kwd3">nuchal pain</keyword><keyword xml:id="kwd4">dystonia</keyword><keyword xml:id="kwd5">transcranial sonography</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Some patients with cervical disc herniation suffer from persistent nuchal pain and muscle spasms after decompressive surgery despite the lack of clinical and radiological signs for actual spinal root compression. Sonographic examination of the brain in some of these patients showed increased echogenicity of the lentiform nuclei as described in patients with idiopathic dystonia. This has been linked to an altered Menkes protein level and copper metabolism. We suggest a relationship between persistent nuchal pain after adequate cervical disc surgery and dystonic movement disorders. Thirteen patients with persistent nonradicular nuchal pain after at least one cervical disc surgery and without evidence of continuing spinal root compression and 13 age‐matched controls were included. All patients had a complete neurological examination, ultrasound, and MRI scan of the brain. In addition, Menkes protein mRNA levels of leucocytes were analyzed in patients and controls. All patients with persistent nuchal pain exhibited a constant tonic unilateral shoulder elevation associated with an ipsilateral hypertrophy of the trapezius muscle. Ultrasound examination showed an increased echogenicity of the lentiform nucleus in one patient unilaterally and in 10 patients bilaterally but in none of the controls. On MRI the T2‐values of the lentiform nuclei were found to be higher in patients exhibiting a hyperechogenicity of the lentiform nuclei compared to controls (<i>P</i> = 0.01). In addition, Menkes protein mRNA levels were decreased in patients with cervical disc herniation (<i>P</i> = 0.03). Clinical, neuroimaging, and biochemical findings of this selected patient sample with chronic nuchal pain and muscle spasms after cervical disc surgery resemble alterations in patients with idiopathic cervical dystonia. This suggests a link between both disorders. A peripheral trauma to the nerve roots may precipitate dystonic movements in susceptible patients and chronic dystonic muscle contraction would account for the persistent nuchal pain. © 2002 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Evidence for shoulder girdle dystonia in selected patients with cervical disc prolapse</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Dystonia and Cervical Disc Prolapse</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Evidence for shoulder girdle dystonia in selected patients with cervical disc prolapse</title></titleInfo><name type="personal"><namePart type="given">Georg</namePart><namePart type="family">Becker</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation><description>Correspondence: Department of Neurology, Universität des Saarlandes, Gebäude 90, 66421 Homburg/Saar, Germany</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Daniela</namePart><namePart type="family">Berg</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Niels</namePart><namePart type="family">Kruse</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ute</namePart><namePart type="family">Schröder</namePart><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Monika</namePart><namePart type="family">Warmuth‐Metz</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Division of Neuroradiology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Peter</namePart><namePart type="family">Rieckmann</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Markus</namePart><namePart type="family">Naumann</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Karlheinz</namePart><namePart type="family">Reiners</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Bayerische Julius‐Maximilians‐Universität Würzburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">New York</placeTerm></place><dateIssued encoding="w3cdtf">2002-07</dateIssued><dateCaptured encoding="w3cdtf">2001-04-18</dateCaptured><dateValid encoding="w3cdtf">2001-12-17</dateValid><copyrightDate encoding="w3cdtf">2002</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">3</extent><extent unit="tables">1</extent><extent unit="references">21</extent><extent unit="words">3854</extent></physicalDescription><abstract lang="en">Some patients with cervical disc herniation suffer from persistent nuchal pain and muscle spasms after decompressive surgery despite the lack of clinical and radiological signs for actual spinal root compression. Sonographic examination of the brain in some of these patients showed increased echogenicity of the lentiform nuclei as described in patients with idiopathic dystonia. This has been linked to an altered Menkes protein level and copper metabolism. We suggest a relationship between persistent nuchal pain after adequate cervical disc surgery and dystonic movement disorders. Thirteen patients with persistent nonradicular nuchal pain after at least one cervical disc surgery and without evidence of continuing spinal root compression and 13 age‐matched controls were included. All patients had a complete neurological examination, ultrasound, and MRI scan of the brain. In addition, Menkes protein mRNA levels of leucocytes were analyzed in patients and controls. All patients with persistent nuchal pain exhibited a constant tonic unilateral shoulder elevation associated with an ipsilateral hypertrophy of the trapezius muscle. Ultrasound examination showed an increased echogenicity of the lentiform nucleus in one patient unilaterally and in 10 patients bilaterally but in none of the controls. On MRI the T2‐values of the lentiform nuclei were found to be higher in patients exhibiting a hyperechogenicity of the lentiform nuclei compared to controls (P = 0.01). In addition, Menkes protein mRNA levels were decreased in patients with cervical disc herniation (P = 0.03). Clinical, neuroimaging, and biochemical findings of this selected patient sample with chronic nuchal pain and muscle spasms after cervical disc surgery resemble alterations in patients with idiopathic cervical dystonia. This suggests a link between both disorders. A peripheral trauma to the nerve roots may precipitate dystonic movements in susceptible patients and chronic dystonic muscle contraction would account for the persistent nuchal pain. © 2002 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>cervical disc herniation</topic><topic>spinal root compression</topic><topic>nuchal pain</topic><topic>dystonia</topic><topic>transcranial sonography</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><detail type="issue"><caption>no.</caption><number>4</number></detail><extent unit="pages"><start>710</start><end>716</end><total>7</total></extent></part></relatedItem><identifier type="istex">CE5656C05B381CBFC382FB9BA4F0D9BEF0CE8830</identifier><identifier type="DOI">10.1002/mds.10132</identifier><identifier type="ArticleID">MDS10132</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2002 Movement Disorders Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000518 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000518 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:CE5656C05B381CBFC382FB9BA4F0D9BEF0CE8830
|texte= Evidence for shoulder girdle dystonia in selected patients with cervical disc prolapse
}}
| This area was generated with Dilib version V0.6.23. |  |