Force control and disease severity in Parkinson's disease
Identifieur interne : 000362 ( Istex/Corpus ); précédent : 000361; suivant : 000363Force control and disease severity in Parkinson's disease
Auteurs : Julie A. Robichaud ; Kerstin D. Pfann ; David E. Vaillancourt ; Cynthia L. Comella ; Daniel M. CorcosSource :
- Movement Disorders [ 0885-3185 ] ; 2005-04.
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Abstract
Several measures of isometric contractions reflect motor impairments in subjects with Parkinson's disease (PD), including long relaxation times and greater power in the 5 to 15 Hz electromyographic (EMG) bandwidth during the holding phase of contractions compared to those measures in healthy subjects. We sought to determine whether the impairments observed in subjects with PD in the performance of isometric contractions reflect disease severity. Twenty‐eight subjects with PD performed isometric contractions at a torque level equal to 50% of the torque generated during a maximum voluntary contraction while off medication. Subjects were instructed to reach the target torque as fast as possible upon hearing the auditory “go” signal and to relax their muscles when a second auditory cue signaled the end of the hold phase. There was a significant positive correlation between torque relaxation time and Unified Parkinson's Disease Rating Scale (UPDRS)‐Motor score. A significant positive correlation was also observed between the proportion of power in the 5 to 15 Hz frequency bin of the agonist EMG signal and UPDRS‐Motor score, and a significant negative correlation between the proportion of power in the 15 to 30 Hz frequency bin and UPDRS‐Motor score. These measures provide objective quantification of the severity of motor impairment that can be used to investigate the efficacy of different interventions in individuals with PD. © 2004 Movement Disorder Society
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DOI: 10.1002/mds.20350
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ISTEX:01B4FAACD0F1B7507F971A5B0E67EF1A28321CA2Le document en format XML
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We sought to determine whether the impairments observed in subjects with PD in the performance of isometric contractions reflect disease severity. Twenty‐eight subjects with PD performed isometric contractions at a torque level equal to 50% of the torque generated during a maximum voluntary contraction while off medication. Subjects were instructed to reach the target torque as fast as possible upon hearing the auditory “go” signal and to relax their muscles when a second auditory cue signaled the end of the hold phase. There was a significant positive correlation between torque relaxation time and Unified Parkinson's Disease Rating Scale (UPDRS)‐Motor score. A significant positive correlation was also observed between the proportion of power in the 5 to 15 Hz frequency bin of the agonist EMG signal and UPDRS‐Motor score, and a significant negative correlation between the proportion of power in the 15 to 30 Hz frequency bin and UPDRS‐Motor score. 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These measures provide objective quantification of the severity of motor impairment that can be used to investigate the efficacy of different interventions in individuals with PD. © 2004 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>isometric contractions</term></item><item><term>EMG</term></item><item><term>frequency analysis</term></item><item><term>muscle relaxation</term></item><item><term>Parkinson's disease</term></item><item><term>disease severity</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Research Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2004-02-18">Received</change><change when="2004-07-04">Registration</change><change when="2005-04">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/01B4FAACD0F1B7507F971A5B0E67EF1A28321CA2/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="short">Mov. 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We sought to determine whether the impairments observed in subjects with PD in the performance of isometric contractions reflect disease severity. Twenty‐eight subjects with PD performed isometric contractions at a torque level equal to 50% of the torque generated during a maximum voluntary contraction while <i>off</i> medication. Subjects were instructed to reach the target torque as fast as possible upon hearing the auditory “go” signal and to relax their muscles when a second auditory cue signaled the end of the hold phase. There was a significant positive correlation between torque relaxation time and Unified Parkinson's Disease Rating Scale (UPDRS)‐Motor score. A significant positive correlation was also observed between the proportion of power in the 5 to 15 Hz frequency bin of the agonist EMG signal and UPDRS‐Motor score, and a significant negative correlation between the proportion of power in the 15 to 30 Hz frequency bin and UPDRS‐Motor score. These measures provide objective quantification of the severity of motor impairment that can be used to investigate the efficacy of different interventions in individuals with PD. © 2004 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Force control and disease severity in Parkinson's disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Force Control in Parkinson's Disease</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Force control and disease severity in Parkinson's disease</title></titleInfo><name type="personal"><namePart type="given">Julie A.</namePart><namePart type="family">Robichaud</namePart><namePart type="termsOfAddress">PT, PhD</namePart><affiliation>Department of Physical Therapy, School of Health and Rehabilitation Sciences, Indiana University, Indianapolis, Indiana, USA</affiliation><description>Correspondence: Department of Physical Therapy, School of Health and Rehabilitation Sciences, Indiana University, 1140 W. Michigan Street, Coleman Hall 326, Indianapolis, IN 46202</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Kerstin D.</namePart><namePart type="family">Pfann</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Movement Sciences (M/C 994), University of Illinois at Chicago, Chicago, Illinois, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">David E.</namePart><namePart type="family">Vaillancourt</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Movement Sciences (M/C 994), University of Illinois at Chicago, Chicago, Illinois, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Cynthia L.</namePart><namePart type="family">Comella</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences, Rush Medical Center, Chicago, Illinois, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Daniel M.</namePart><namePart type="family">Corcos</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Movement Sciences (M/C 994), University of Illinois at Chicago, Chicago, Illinois, USA</affiliation><affiliation>Department of Neurological Sciences, Rush Medical Center, Chicago, Illinois, USA</affiliation><affiliation>Department of Physical Therapy, University of Illinois at Chicago, Chicago, Illinois, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2005-04</dateIssued><dateCaptured encoding="w3cdtf">2004-02-18</dateCaptured><dateValid encoding="w3cdtf">2004-07-04</dateValid><copyrightDate encoding="w3cdtf">2005</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">5</extent><extent unit="tables">2</extent><extent unit="references">31</extent><extent unit="words">6610</extent></physicalDescription><abstract lang="en">Several measures of isometric contractions reflect motor impairments in subjects with Parkinson's disease (PD), including long relaxation times and greater power in the 5 to 15 Hz electromyographic (EMG) bandwidth during the holding phase of contractions compared to those measures in healthy subjects. We sought to determine whether the impairments observed in subjects with PD in the performance of isometric contractions reflect disease severity. Twenty‐eight subjects with PD performed isometric contractions at a torque level equal to 50% of the torque generated during a maximum voluntary contraction while off medication. Subjects were instructed to reach the target torque as fast as possible upon hearing the auditory “go” signal and to relax their muscles when a second auditory cue signaled the end of the hold phase. There was a significant positive correlation between torque relaxation time and Unified Parkinson's Disease Rating Scale (UPDRS)‐Motor score. A significant positive correlation was also observed between the proportion of power in the 5 to 15 Hz frequency bin of the agonist EMG signal and UPDRS‐Motor score, and a significant negative correlation between the proportion of power in the 15 to 30 Hz frequency bin and UPDRS‐Motor score. These measures provide objective quantification of the severity of motor impairment that can be used to investigate the efficacy of different interventions in individuals with PD. © 2004 Movement Disorder Society</abstract><note type="funding">National Institute of Arthritis and Musculoskeletal and Skin Diseases - No. RO1‐AR 33189; </note><note type="funding">National Institute of Neurological Disorders and Stroke - No. RO1‐NS 28127; No. RO1‐NS 40902; No. F32‐NS‐44727; </note><note type="funding">National Institute on Disability and Rehabilitation Research - No. H133P000005; </note><note type="funding">Movement Disorders in the Department of Neurology at Rush–Presbyterian St. Luke's Medical Center</note><subject lang="en"><genre>Keywords</genre><topic>isometric contractions</topic><topic>EMG</topic><topic>frequency analysis</topic><topic>muscle relaxation</topic><topic>Parkinson's disease</topic><topic>disease severity</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>20</number></detail><detail type="issue"><caption>no.</caption><number>4</number></detail><extent unit="pages"><start>441</start><end>450</end><total>10</total></extent></part></relatedItem><identifier type="istex">01B4FAACD0F1B7507F971A5B0E67EF1A28321CA2</identifier><identifier type="DOI">10.1002/mds.20350</identifier><identifier type="ArticleID">MDS20350</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2004 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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