Direct medical costs associated with Parkinson's disease: A population‐based study
Identifieur interne : 000357 ( Istex/Corpus ); précédent : 000356; suivant : 000358Direct medical costs associated with Parkinson's disease: A population‐based study
Auteurs : Cynthia L. Leibson ; Kirsten Hall Long ; Demetrius M. Maraganore ; James H. Bower ; Jeanine E. Ransom ; Peter C. O'Brien ; Walter A. RoccaSource :
- Movement Disorders [ 0885-3185 ] ; 2006-11.
English descriptors
Abstract
The objective was to provide population‐based estimates of incremental medical costs associated with Parkinson's disease (PD) from onset forward. All Olmsted County, Minnesota, residents with confirmed PD onset from 1987 through 1995 (n = 92) and one age‐ and sex‐matched non‐PD referent subject per case were identified with retrospective record review and followed in provider‐linked billing data for direct medical costs (excluding outpatient pharmaceutical costs) from 1 year before index (i.e., year of symptom onset) through 10 years after index. Costs for each referent subject were subtracted from those for his/her matched case. Tests for statistical significance used Wilcoxon signed ranks. Preindex costs were similar [median difference in annual costs (MD) = −$3; P = 0.59]. One year post index, PD subjects exhibited borderline significantly higher costs compared to referent subjects (MD = $581; P = 0.052); the difference diminished over 5 years (MD = $118; P = 0.82). By 5 to 10 years, however, PD subjects exhibited significantly higher costs (MD = $1,146; P = 0.01). Over the full 10 years, excess costs were concentrated among PD subjects without rest tremor (MD = $2,261, P < 0.01, for those without tremor and −$229, P = 0.99, for those with tremor). These population‐based estimates of PD‐associated direct medical costs from onset forward can uniquely inform policy decisions and cost–effectiveness research. © 2006 Movement Disorder Society
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DOI: 10.1002/mds.21075
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Maraganore</name><affiliation><mods:affiliation>Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</mods:affiliation></affiliation></author><author><name sortKey="Bower, James H" sort="Bower, James H" uniqKey="Bower J" first="James H." last="Bower">James H. Bower</name><affiliation><mods:affiliation>Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</mods:affiliation></affiliation></author><author><name sortKey="Ransom, Jeanine E" sort="Ransom, Jeanine E" uniqKey="Ransom J" first="Jeanine E." last="Ransom">Jeanine E. Ransom</name><affiliation><mods:affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</mods:affiliation></affiliation></author><author><name sortKey="O Brien, Peter C" sort="O Brien, Peter C" uniqKey="O Brien P" first="Peter C." last="O'Brien">Peter C. 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Bower</name><affiliation><mods:affiliation>Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</mods:affiliation></affiliation></author><author><name sortKey="Ransom, Jeanine E" sort="Ransom, Jeanine E" uniqKey="Ransom J" first="Jeanine E." last="Ransom">Jeanine E. Ransom</name><affiliation><mods:affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</mods:affiliation></affiliation></author><author><name sortKey="O Brien, Peter C" sort="O Brien, Peter C" uniqKey="O Brien P" first="Peter C." last="O'Brien">Peter C. O'Brien</name><affiliation><mods:affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</mods:affiliation></affiliation></author><author><name sortKey="Rocca, Walter A" sort="Rocca, Walter A" uniqKey="Rocca W" first="Walter A." last="Rocca">Walter A. Rocca</name><affiliation><mods:affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2006-11">2006-11</date><biblScope unit="vol">21</biblScope><biblScope unit="issue">11</biblScope><biblScope unit="page" from="1864">1864</biblScope><biblScope unit="page" to="1871">1871</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">4EE7730B929D2EB6C9A9BC20B10CE96CC9B9CD63</idno><idno type="DOI">10.1002/mds.21075</idno><idno type="ArticleID">MDS21075</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term><term>cost analysis</term><term>costs</term><term>parkinsonian disorders</term><term>utilization</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The objective was to provide population‐based estimates of incremental medical costs associated with Parkinson's disease (PD) from onset forward. All Olmsted County, Minnesota, residents with confirmed PD onset from 1987 through 1995 (n = 92) and one age‐ and sex‐matched non‐PD referent subject per case were identified with retrospective record review and followed in provider‐linked billing data for direct medical costs (excluding outpatient pharmaceutical costs) from 1 year before index (i.e., year of symptom onset) through 10 years after index. Costs for each referent subject were subtracted from those for his/her matched case. Tests for statistical significance used Wilcoxon signed ranks. Preindex costs were similar [median difference in annual costs (MD) = −$3; P = 0.59]. One year post index, PD subjects exhibited borderline significantly higher costs compared to referent subjects (MD = $581; P = 0.052); the difference diminished over 5 years (MD = $118; P = 0.82). By 5 to 10 years, however, PD subjects exhibited significantly higher costs (MD = $1,146; P = 0.01). Over the full 10 years, excess costs were concentrated among PD subjects without rest tremor (MD = $2,261, P < 0.01, for those without tremor and −$229, P = 0.99, for those with tremor). These population‐based estimates of PD‐associated direct medical costs from onset forward can uniquely inform policy decisions and cost–effectiveness research. © 2006 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Cynthia L. Leibson PhD</name><affiliations><json:string>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</json:string></affiliations></json:item><json:item><name>Kirsten Hall Long PhD</name><affiliations><json:string>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</json:string></affiliations></json:item><json:item><name>Demetrius M. Maraganore MD</name><affiliations><json:string>Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</json:string></affiliations></json:item><json:item><name>James H. Bower MD</name><affiliations><json:string>Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</json:string></affiliations></json:item><json:item><name>Jeanine E. Ransom BS</name><affiliations><json:string>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</json:string></affiliations></json:item><json:item><name>Peter C. O'Brien PhD</name><affiliations><json:string>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</json:string></affiliations></json:item><json:item><name>Walter A. Rocca MD, MPH</name><affiliations><json:string>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</json:string><json:string>Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>parkinsonian disorders</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>costs</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>cost analysis</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>utilization</value></json:item></subject><language><json:string>eng</json:string></language><abstract>The objective was to provide population‐based estimates of incremental medical costs associated with Parkinson's disease (PD) from onset forward. All Olmsted County, Minnesota, residents with confirmed PD onset from 1987 through 1995 (n = 92) and one age‐ and sex‐matched non‐PD referent subject per case were identified with retrospective record review and followed in provider‐linked billing data for direct medical costs (excluding outpatient pharmaceutical costs) from 1 year before index (i.e., year of symptom onset) through 10 years after index. Costs for each referent subject were subtracted from those for his/her matched case. Tests for statistical significance used Wilcoxon signed ranks. Preindex costs were similar [median difference in annual costs (MD) = −$3; P = 0.59]. One year post index, PD subjects exhibited borderline significantly higher costs compared to referent subjects (MD = $581; P = 0.052); the difference diminished over 5 years (MD = $118; P = 0.82). By 5 to 10 years, however, PD subjects exhibited significantly higher costs (MD = $1,146; P = 0.01). Over the full 10 years, excess costs were concentrated among PD subjects without rest tremor (MD = $2,261, P > 0.01, for those without tremor and −$229, P = 0.99, for those with tremor). These population‐based estimates of PD‐associated direct medical costs from onset forward can uniquely inform policy decisions and cost–effectiveness research. © 2006 Movement Disorder Society</abstract><qualityIndicators><score>7.7</score><pdfVersion>1.3</pdfVersion><pdfPageSize>594 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>1464</abstractCharCount><pdfWordCount>5418</pdfWordCount><pdfCharCount>32978</pdfCharCount><pdfPageCount>8</pdfPageCount><abstractWordCount>225</abstractWordCount></qualityIndicators><title>Direct medical costs associated with Parkinson's disease: A population‐based study</title><genre><json:string>Serial article</json:string></genre><host><volume>21</volume><pages><total>8</total><last>1871</last><first>1864</first></pages><issn><json:string>0885-3185</json:string></issn><issue>11</issue><subject><json:item><value>Research Article</value></json:item></subject><genre></genre><language><json:string>unknown</json:string></language><title>Movement Disorders</title><doi><json:string>10.1002/(ISSN)1531-8257</json:string></doi></host><publicationDate>2006</publicationDate><copyrightDate>2006</copyrightDate><doi><json:string>10.1002/mds.21075</json:string></doi><id>4EE7730B929D2EB6C9A9BC20B10CE96CC9B9CD63</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/4EE7730B929D2EB6C9A9BC20B10CE96CC9B9CD63/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/4EE7730B929D2EB6C9A9BC20B10CE96CC9B9CD63/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/4EE7730B929D2EB6C9A9BC20B10CE96CC9B9CD63/fulltext/tei"><teiHeader type="text"><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Direct medical costs associated with Parkinson's disease: A population‐based study</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><p>Wiley Subscription Services, Inc., A Wiley Company</p></availability><date>2006</date></publicationStmt><notesStmt><note>Pfizer Pharmaceuticals</note><note>National Institute of Neurological Disorders - No. RO1 NS33978;</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Direct medical costs associated with Parkinson's disease: A population‐based study</title><author><persName><forename type="first">Cynthia L.</forename><surname>Leibson</surname><roleName type="degree">PhD</roleName></persName><note type="correspondence"><p>Correspondence: Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905</p></note><affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation></author><author><persName><forename type="first">Kirsten Hall</forename><surname>Long</surname><roleName type="degree">PhD</roleName></persName><affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation></author><author><persName><forename type="first">Demetrius M.</forename><surname>Maraganore</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation></author><author><persName><forename type="first">James H.</forename><surname>Bower</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation></author><author><persName><forename type="first">Jeanine E.</forename><surname>Ransom</surname><roleName type="degree">BS</roleName></persName><affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation></author><author><persName><forename type="first">Peter C.</forename><surname>O'Brien</surname><roleName type="degree">PhD</roleName></persName><affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation></author><author><persName><forename type="first">Walter A.</forename><surname>Rocca</surname><roleName type="degree">MD, MPH</roleName></persName><affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation><affiliation>Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation></author></analytic><monogr><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. 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All Olmsted County, Minnesota, residents with confirmed PD onset from 1987 through 1995 (n = 92) and one age‐ and sex‐matched non‐PD referent subject per case were identified with retrospective record review and followed in provider‐linked billing data for direct medical costs (excluding outpatient pharmaceutical costs) from 1 year before index (i.e., year of symptom onset) through 10 years after index. Costs for each referent subject were subtracted from those for his/her matched case. Tests for statistical significance used Wilcoxon signed ranks. Preindex costs were similar [median difference in annual costs (MD) = −$3; P = 0.59]. One year post index, PD subjects exhibited borderline significantly higher costs compared to referent subjects (MD = $581; P = 0.052); the difference diminished over 5 years (MD = $118; P = 0.82). By 5 to 10 years, however, PD subjects exhibited significantly higher costs (MD = $1,146; P = 0.01). Over the full 10 years, excess costs were concentrated among PD subjects without rest tremor (MD = $2,261, P < 0.01, for those without tremor and −$229, P = 0.99, for those with tremor). These population‐based estimates of PD‐associated direct medical costs from onset forward can uniquely inform policy decisions and cost–effectiveness research. © 2006 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Parkinson's disease</term></item><item><term>parkinsonian disorders</term></item><item><term>costs</term></item><item><term>cost analysis</term></item><item><term>utilization</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Research Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2005-10-31">Received</change><change when="2006-04-18">Registration</change><change when="2006-11">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/4EE7730B929D2EB6C9A9BC20B10CE96CC9B9CD63/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="subtitle">Official Journal of the Movement Disorder Society</title><title type="short">Mov. 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type="main">Abstract</title><p>The objective was to provide population‐based estimates of incremental medical costs associated with Parkinson's disease (PD) from onset forward. All Olmsted County, Minnesota, residents with confirmed PD onset from 1987 through 1995 (n = 92) and one age‐ and sex‐matched non‐PD referent subject per case were identified with retrospective record review and followed in provider‐linked billing data for direct medical costs (excluding outpatient pharmaceutical costs) from 1 year before index (i.e., year of symptom onset) through 10 years after index. Costs for each referent subject were subtracted from those for his/her matched case. Tests for statistical significance used Wilcoxon signed ranks. Preindex costs were similar [median difference in annual costs (MD) = −$3; <i>P</i> = 0.59]. One year post index, PD subjects exhibited borderline significantly higher costs compared to referent subjects (MD = $581; <i>P</i> = 0.052); the difference diminished over 5 years (MD = $118; <i>P</i> = 0.82). By 5 to 10 years, however, PD subjects exhibited significantly higher costs (MD = $1,146; <i>P</i> = 0.01). Over the full 10 years, excess costs were concentrated among PD subjects without rest tremor (MD = $2,261, <i>P</i> < 0.01, for those without tremor and −$229, <i>P</i> = 0.99, for those with tremor). These population‐based estimates of PD‐associated direct medical costs from onset forward can uniquely inform policy decisions and cost–effectiveness research. © 2006 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Direct medical costs associated with Parkinson's disease: A population‐based study</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Parkinson's Disease Medical Costs</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Direct medical costs associated with Parkinson's disease: A population‐based study</title></titleInfo><name type="personal"><namePart type="given">Cynthia L.</namePart><namePart type="family">Leibson</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation><description>Correspondence: Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Kirsten Hall</namePart><namePart type="family">Long</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Demetrius M.</namePart><namePart type="family">Maraganore</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">James H.</namePart><namePart type="family">Bower</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jeanine E.</namePart><namePart type="family">Ransom</namePart><namePart type="termsOfAddress">BS</namePart><affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Peter C.</namePart><namePart type="family">O'Brien</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Walter A.</namePart><namePart type="family">Rocca</namePart><namePart type="termsOfAddress">MD, MPH</namePart><affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation><affiliation>Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2006-11</dateIssued><dateCaptured encoding="w3cdtf">2005-10-31</dateCaptured><dateValid encoding="w3cdtf">2006-04-18</dateValid><copyrightDate encoding="w3cdtf">2006</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="tables">1</extent><extent unit="references">35</extent><extent unit="words">5985</extent></physicalDescription><abstract lang="en">The objective was to provide population‐based estimates of incremental medical costs associated with Parkinson's disease (PD) from onset forward. All Olmsted County, Minnesota, residents with confirmed PD onset from 1987 through 1995 (n = 92) and one age‐ and sex‐matched non‐PD referent subject per case were identified with retrospective record review and followed in provider‐linked billing data for direct medical costs (excluding outpatient pharmaceutical costs) from 1 year before index (i.e., year of symptom onset) through 10 years after index. Costs for each referent subject were subtracted from those for his/her matched case. Tests for statistical significance used Wilcoxon signed ranks. Preindex costs were similar [median difference in annual costs (MD) = −$3; P = 0.59]. One year post index, PD subjects exhibited borderline significantly higher costs compared to referent subjects (MD = $581; P = 0.052); the difference diminished over 5 years (MD = $118; P = 0.82). By 5 to 10 years, however, PD subjects exhibited significantly higher costs (MD = $1,146; P = 0.01). Over the full 10 years, excess costs were concentrated among PD subjects without rest tremor (MD = $2,261, P < 0.01, for those without tremor and −$229, P = 0.99, for those with tremor). These population‐based estimates of PD‐associated direct medical costs from onset forward can uniquely inform policy decisions and cost–effectiveness research. © 2006 Movement Disorder Society</abstract><note type="funding">Pfizer Pharmaceuticals</note><note type="funding">National Institute of Neurological Disorders - No. RO1 NS33978; </note><subject lang="en"><genre>Keywords</genre><topic>Parkinson's disease</topic><topic>parkinsonian disorders</topic><topic>costs</topic><topic>cost analysis</topic><topic>utilization</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>21</number></detail><detail type="issue"><caption>no.</caption><number>11</number></detail><extent unit="pages"><start>1864</start><end>1871</end><total>8</total></extent></part></relatedItem><identifier type="istex">4EE7730B929D2EB6C9A9BC20B10CE96CC9B9CD63</identifier><identifier type="DOI">10.1002/mds.21075</identifier><identifier type="ArticleID">MDS21075</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2006 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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