Grip force behavior in Gilles de la Tourette syndrome
Identifieur interne : 000326 ( Istex/Corpus ); précédent : 000325; suivant : 000327Grip force behavior in Gilles de la Tourette syndrome
Auteurs : Dennis A. Nowak ; John Rothwell ; Helge Topka ; Mary M. Robertson ; Michael OrthSource :
- Movement Disorders [ 0885-3185 ] ; 2005-02.
English descriptors
Abstract
We analyzed predictive and reactive grip force behavior in 15 patients with Gilles de la Tourette syndrome (GTS) and 15 sex‐ and age‐matched healthy control subjects. Nine patients were without medication; six patients were on medication. In a first experiment, participants lifted and held instrumented objects of different weight. In a second experiment, participants performed vertical point‐to‐point and continuous arm movements at different frequencies with a hand‐held object. In a third experiment, preparatory and reactive grip force responses to sudden load perturbations were analyzed when a weight was dropped into a hand‐held cup either by the subject or unexpectedly by the experimenter. Compared to the healthy subjects, GTS patients had increased grip forces relative to the load force in all tasks. Despite this finding, they adjusted the grip force to changes in load force (due to either a change in the mass lifted or accelerating the mass during continuous movements) in the same way as healthy subjects. The temporal coupling between grip and load force profiles was also similar in patients and healthy controls, and they displayed normal anticipation of impact forces when they dropped a weight into a hand‐held cup. We found no significant effect of medication on the performance of GTS patients, regardless of the task performed. These results are consistent with deficient sensory–motor processing in Gilles de la Tourette syndrome. © 2004 Movement Disorder Society
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DOI: 10.1002/mds.20309
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ISTEX:78D961FAA856141CBDA5E4C33756EEC0A467B43DLe document en format XML
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Nowak</name><affiliation><mods:affiliation>Sobell Department of Motor Neuroscience and Movements Disorders, Institute of Neurology, University of London, London, United Kingdom</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Neurology and Clinical Neurophysiology, Academic Hospital Bogenhausen of the Technical University of Munich, Munich, Germany</mods:affiliation></affiliation></author><author><name sortKey="Rothwell, John" sort="Rothwell, John" uniqKey="Rothwell J" first="John" last="Rothwell">John Rothwell</name><affiliation><mods:affiliation>Sobell Department of Motor Neuroscience and Movements Disorders, Institute of Neurology, University of London, London, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Topka, Helge" sort="Topka, Helge" uniqKey="Topka H" first="Helge" last="Topka">Helge Topka</name><affiliation><mods:affiliation>Department of Neurology and Clinical Neurophysiology, Academic Hospital Bogenhausen of the Technical University of Munich, Munich, Germany</mods:affiliation></affiliation></author><author><name sortKey="Robertson, Mary M" sort="Robertson, Mary M" uniqKey="Robertson M" first="Mary M." last="Robertson">Mary M. 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Nine patients were without medication; six patients were on medication. In a first experiment, participants lifted and held instrumented objects of different weight. In a second experiment, participants performed vertical point‐to‐point and continuous arm movements at different frequencies with a hand‐held object. In a third experiment, preparatory and reactive grip force responses to sudden load perturbations were analyzed when a weight was dropped into a hand‐held cup either by the subject or unexpectedly by the experimenter. Compared to the healthy subjects, GTS patients had increased grip forces relative to the load force in all tasks. Despite this finding, they adjusted the grip force to changes in load force (due to either a change in the mass lifted or accelerating the mass during continuous movements) in the same way as healthy subjects. The temporal coupling between grip and load force profiles was also similar in patients and healthy controls, and they displayed normal anticipation of impact forces when they dropped a weight into a hand‐held cup. We found no significant effect of medication on the performance of GTS patients, regardless of the task performed. These results are consistent with deficient sensory–motor processing in Gilles de la Tourette syndrome. © 2004 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Dennis A. Nowak MD</name><affiliations><json:string>Sobell Department of Motor Neuroscience and Movements Disorders, Institute of Neurology, University of London, London, United Kingdom</json:string><json:string>Department of Neurology and Clinical Neurophysiology, Academic Hospital Bogenhausen of the Technical University of Munich, Munich, Germany</json:string></affiliations></json:item><json:item><name>John Rothwell PhD</name><affiliations><json:string>Sobell Department of Motor Neuroscience and Movements Disorders, Institute of Neurology, University of London, London, United Kingdom</json:string></affiliations></json:item><json:item><name>Helge Topka MD</name><affiliations><json:string>Department of Neurology and Clinical Neurophysiology, Academic Hospital Bogenhausen of the Technical University of Munich, Munich, Germany</json:string></affiliations></json:item><json:item><name>Mary M. Robertson MD</name><affiliations><json:string>Department of Psychiatry and Behavioural Sciences, University College and the National Hospital for Neurology and Neurosurgery, London, United Kingdom</json:string><json:string>Department of Neuropsychiatry, The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom</json:string></affiliations></json:item><json:item><name>Michael Orth MD</name><affiliations><json:string>Sobell Department of Motor Neuroscience and Movements Disorders, Institute of Neurology, University of London, London, United Kingdom</json:string><json:string>Department of Neuropsychiatry, The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>grip force</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>object manipulation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>predictive force control</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Gilles de la Tourette syndrome</value></json:item></subject><language><json:string>eng</json:string></language><abstract>We analyzed predictive and reactive grip force behavior in 15 patients with Gilles de la Tourette syndrome (GTS) and 15 sex‐ and age‐matched healthy control subjects. Nine patients were without medication; six patients were on medication. In a first experiment, participants lifted and held instrumented objects of different weight. In a second experiment, participants performed vertical point‐to‐point and continuous arm movements at different frequencies with a hand‐held object. In a third experiment, preparatory and reactive grip force responses to sudden load perturbations were analyzed when a weight was dropped into a hand‐held cup either by the subject or unexpectedly by the experimenter. Compared to the healthy subjects, GTS patients had increased grip forces relative to the load force in all tasks. Despite this finding, they adjusted the grip force to changes in load force (due to either a change in the mass lifted or accelerating the mass during continuous movements) in the same way as healthy subjects. The temporal coupling between grip and load force profiles was also similar in patients and healthy controls, and they displayed normal anticipation of impact forces when they dropped a weight into a hand‐held cup. We found no significant effect of medication on the performance of GTS patients, regardless of the task performed. 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Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2005-02"></date><biblScope unit="vol">20</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="217">217</biblScope><biblScope unit="page" to="223">223</biblScope></imprint></monogr><idno type="istex">78D961FAA856141CBDA5E4C33756EEC0A467B43D</idno><idno type="DOI">10.1002/mds.20309</idno><idno type="ArticleID">MDS20309</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2005</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>We analyzed predictive and reactive grip force behavior in 15 patients with Gilles de la Tourette syndrome (GTS) and 15 sex‐ and age‐matched healthy control subjects. Nine patients were without medication; six patients were on medication. In a first experiment, participants lifted and held instrumented objects of different weight. In a second experiment, participants performed vertical point‐to‐point and continuous arm movements at different frequencies with a hand‐held object. In a third experiment, preparatory and reactive grip force responses to sudden load perturbations were analyzed when a weight was dropped into a hand‐held cup either by the subject or unexpectedly by the experimenter. Compared to the healthy subjects, GTS patients had increased grip forces relative to the load force in all tasks. Despite this finding, they adjusted the grip force to changes in load force (due to either a change in the mass lifted or accelerating the mass during continuous movements) in the same way as healthy subjects. The temporal coupling between grip and load force profiles was also similar in patients and healthy controls, and they displayed normal anticipation of impact forces when they dropped a weight into a hand‐held cup. We found no significant effect of medication on the performance of GTS patients, regardless of the task performed. These results are consistent with deficient sensory–motor processing in Gilles de la Tourette syndrome. © 2004 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>grip force</term></item><item><term>object manipulation</term></item><item><term>predictive force control</term></item><item><term>Gilles de la Tourette syndrome</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Brief Report</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2004-02-04">Received</change><change when="2004-05-29">Registration</change><change when="2005-02">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/78D961FAA856141CBDA5E4C33756EEC0A467B43D/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="subtitle">Official Journal of the Movement Disorder Society</title><title type="short">Mov. 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type="main" xml:lang="en"><title type="main">Abstract</title><p>We analyzed predictive and reactive grip force behavior in 15 patients with Gilles de la Tourette syndrome (GTS) and 15 sex‐ and age‐matched healthy control subjects. Nine patients were without medication; six patients were on medication. In a first experiment, participants lifted and held instrumented objects of different weight. In a second experiment, participants performed vertical point‐to‐point and continuous arm movements at different frequencies with a hand‐held object. In a third experiment, preparatory and reactive grip force responses to sudden load perturbations were analyzed when a weight was dropped into a hand‐held cup either by the subject or unexpectedly by the experimenter. Compared to the healthy subjects, GTS patients had increased grip forces relative to the load force in all tasks. Despite this finding, they adjusted the grip force to changes in load force (due to either a change in the mass lifted or accelerating the mass during continuous movements) in the same way as healthy subjects. The temporal coupling between grip and load force profiles was also similar in patients and healthy controls, and they displayed normal anticipation of impact forces when they dropped a weight into a hand‐held cup. We found no significant effect of medication on the performance of GTS patients, regardless of the task performed. These results are consistent with deficient sensory–motor processing in Gilles de la Tourette syndrome. © 2004 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Grip force behavior in Gilles de la Tourette syndrome</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Grip force behavior in TS</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Grip force behavior in Gilles de la Tourette syndrome</title></titleInfo><name type="personal"><namePart type="given">Dennis A.</namePart><namePart type="family">Nowak</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Sobell Department of Motor Neuroscience and Movements Disorders, Institute of Neurology, University of London, London, United Kingdom</affiliation><affiliation>Department of Neurology and Clinical Neurophysiology, Academic Hospital Bogenhausen of the Technical University of Munich, Munich, Germany</affiliation><description>Correspondence: Department of Neurology & Clinical Neurophysiology, Academic Hospital Academic Hospital München Bogenhausen, Technical University of Munich, Englschalkingerstrasse 77, D‐81925 Munich, Germany</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">John</namePart><namePart type="family">Rothwell</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Sobell Department of Motor Neuroscience and Movements Disorders, Institute of Neurology, University of London, London, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Helge</namePart><namePart type="family">Topka</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology and Clinical Neurophysiology, Academic Hospital Bogenhausen of the Technical University of Munich, Munich, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Mary M.</namePart><namePart type="family">Robertson</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Psychiatry and Behavioural Sciences, University College and the National Hospital for Neurology and Neurosurgery, London, United Kingdom</affiliation><affiliation>Department of Neuropsychiatry, The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Michael</namePart><namePart type="family">Orth</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Sobell Department of Motor Neuroscience and Movements Disorders, Institute of Neurology, University of London, London, United Kingdom</affiliation><affiliation>Department of Neuropsychiatry, The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2005-02</dateIssued><dateCaptured encoding="w3cdtf">2004-02-04</dateCaptured><dateValid encoding="w3cdtf">2004-05-29</dateValid><copyrightDate encoding="w3cdtf">2005</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">2</extent><extent unit="tables">2</extent><extent unit="references">33</extent><extent unit="words">5380</extent></physicalDescription><abstract lang="en">We analyzed predictive and reactive grip force behavior in 15 patients with Gilles de la Tourette syndrome (GTS) and 15 sex‐ and age‐matched healthy control subjects. Nine patients were without medication; six patients were on medication. In a first experiment, participants lifted and held instrumented objects of different weight. In a second experiment, participants performed vertical point‐to‐point and continuous arm movements at different frequencies with a hand‐held object. In a third experiment, preparatory and reactive grip force responses to sudden load perturbations were analyzed when a weight was dropped into a hand‐held cup either by the subject or unexpectedly by the experimenter. Compared to the healthy subjects, GTS patients had increased grip forces relative to the load force in all tasks. Despite this finding, they adjusted the grip force to changes in load force (due to either a change in the mass lifted or accelerating the mass during continuous movements) in the same way as healthy subjects. The temporal coupling between grip and load force profiles was also similar in patients and healthy controls, and they displayed normal anticipation of impact forces when they dropped a weight into a hand‐held cup. We found no significant effect of medication on the performance of GTS patients, regardless of the task performed. These results are consistent with deficient sensory–motor processing in Gilles de la Tourette syndrome. © 2004 Movement Disorder Society</abstract><note type="funding">Deutsche Gesellschaft für Klinische Neurophysiologie</note><subject lang="en"><genre>Keywords</genre><topic>grip force</topic><topic>object manipulation</topic><topic>predictive force control</topic><topic>Gilles de la Tourette syndrome</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>20</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>217</start><end>223</end><total>7</total></extent></part></relatedItem><identifier type="istex">78D961FAA856141CBDA5E4C33756EEC0A467B43D</identifier><identifier type="DOI">10.1002/mds.20309</identifier><identifier type="ArticleID">MDS20309</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2004 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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