Computed tomographic findings in progressive supranuclear palsy: Correlation with clinical grade
Identifieur interne : 004598 ( Istex/Checkpoint ); précédent : 004597; suivant : 004599Computed tomographic findings in progressive supranuclear palsy: Correlation with clinical grade
Auteurs : Schonfeld [États-Unis] ; Lawrence I. Golbe [États-Unis] ; Jacob I. Sage [États-Unis] ; Jan N. Safer [États-Unis] ; Roger C. Duvoisin [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 1987.
English descriptors
Abstract
We report clinical and computed tomography (CT) findings in 17 patients with progressive supranuclear palsy (PSP). Patients were divided into four clinical groups according to the severity of the disease and functional disability. In Grade 1, patients demonstrated minor disability and decreased anteroposterior (AP) diameter of the midbrain tegmentum was present. As the disease progressed clinically to Grade 2, more severe atrophy of the pons and midbrain and dilation of the quadrigeminal plate cistern were noted. The most severe stages of clinical disability (Grades 3 and 4) were characterized radiologically by dilatation of the aqueduct, progressive dilatation of the third and fourth ventricles and atrophy of the temporal lobes. Cortical atrophy was variable and not a prominent radiological feature. Midbrain and pontine AP diameters were significantly smaller in PSP patients than normal patients. Serial studies showed progressive involution of the pons and midbrain and enlargement of the third ventricle. While the most obvious CT changes in PSP occur late in the disease, CT may in fact suggest the correct diagnosis long before the classic clinical picture is evident.
Url:
DOI: 10.1002/mds.870020404
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
ISTEX:BABB09EE0A410D78CD6666F45B6F8EBCD6B6AAE8Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Computed tomographic findings in progressive supranuclear palsy: Correlation with clinical grade</title><author><name sortKey="Schonfeld" sort="Schonfeld" uniqKey="Schonfeld" last="Schonfeld">Schonfeld</name></author><author><name sortKey="Golbe, Lawrence I" sort="Golbe, Lawrence I" uniqKey="Golbe L" first="Lawrence I." last="Golbe">Lawrence I. Golbe</name></author><author><name sortKey="Sage, Jacob I" sort="Sage, Jacob I" uniqKey="Sage J" first="Jacob I." last="Sage">Jacob I. Sage</name></author><author><name sortKey="Safer, Jan N" sort="Safer, Jan N" uniqKey="Safer J" first="Jan N." last="Safer">Jan N. Safer</name></author><author><name sortKey="Duvoisin, Roger C" sort="Duvoisin, Roger C" uniqKey="Duvoisin R" first="Roger C." last="Duvoisin">Roger C. Duvoisin</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:BABB09EE0A410D78CD6666F45B6F8EBCD6B6AAE8</idno><date when="1987" year="1987">1987</date><idno type="doi">10.1002/mds.870020404</idno><idno type="url">https://api.istex.fr/document/BABB09EE0A410D78CD6666F45B6F8EBCD6B6AAE8/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001E92</idno><idno type="wicri:Area/Istex/Curation">001E92</idno><idno type="wicri:Area/Istex/Checkpoint">004598</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Computed tomographic findings in progressive supranuclear palsy: Correlation with clinical grade</title><author><name sortKey="Schonfeld" sort="Schonfeld" uniqKey="Schonfeld" last="Schonfeld">Schonfeld</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Departments of Radiology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Academic Health Science Center, New Brunswick, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Golbe, Lawrence I" sort="Golbe, Lawrence I" uniqKey="Golbe L" first="Lawrence I." last="Golbe">Lawrence I. Golbe</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Departments of Neurology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Academic Health Science Center, New Brunswick, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Sage, Jacob I" sort="Sage, Jacob I" uniqKey="Sage J" first="Jacob I." last="Sage">Jacob I. Sage</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Departments of Neurology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Academic Health Science Center, New Brunswick, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Safer, Jan N" sort="Safer, Jan N" uniqKey="Safer J" first="Jan N." last="Safer">Jan N. Safer</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Departments of Radiology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Academic Health Science Center, New Brunswick, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Duvoisin, Roger C" sort="Duvoisin, Roger C" uniqKey="Duvoisin R" first="Roger C." last="Duvoisin">Roger C. Duvoisin</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Departments of Neurology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Academic Health Science Center, New Brunswick, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="1987">1987</date><biblScope unit="vol">2</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="263">263</biblScope><biblScope unit="page" to="278">278</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">BABB09EE0A410D78CD6666F45B6F8EBCD6B6AAE8</idno><idno type="DOI">10.1002/mds.870020404</idno><idno type="ArticleID">MDS870020404</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Computed tomography</term><term>Parkinsonism</term><term>Progressive supranuclear palsy</term><term>Voluntary gaze paresis</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We report clinical and computed tomography (CT) findings in 17 patients with progressive supranuclear palsy (PSP). Patients were divided into four clinical groups according to the severity of the disease and functional disability. In Grade 1, patients demonstrated minor disability and decreased anteroposterior (AP) diameter of the midbrain tegmentum was present. As the disease progressed clinically to Grade 2, more severe atrophy of the pons and midbrain and dilation of the quadrigeminal plate cistern were noted. The most severe stages of clinical disability (Grades 3 and 4) were characterized radiologically by dilatation of the aqueduct, progressive dilatation of the third and fourth ventricles and atrophy of the temporal lobes. Cortical atrophy was variable and not a prominent radiological feature. Midbrain and pontine AP diameters were significantly smaller in PSP patients than normal patients. Serial studies showed progressive involution of the pons and midbrain and enlargement of the third ventricle. While the most obvious CT changes in PSP occur late in the disease, CT may in fact suggest the correct diagnosis long before the classic clinical picture is evident.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>New Jersey</li></region></list><tree><country name="États-Unis"><region name="New Jersey"><name sortKey="Schonfeld" sort="Schonfeld" uniqKey="Schonfeld" last="Schonfeld">Schonfeld</name></region><name sortKey="Duvoisin, Roger C" sort="Duvoisin, Roger C" uniqKey="Duvoisin R" first="Roger C." last="Duvoisin">Roger C. Duvoisin</name><name sortKey="Golbe, Lawrence I" sort="Golbe, Lawrence I" uniqKey="Golbe L" first="Lawrence I." last="Golbe">Lawrence I. Golbe</name><name sortKey="Safer, Jan N" sort="Safer, Jan N" uniqKey="Safer J" first="Jan N." last="Safer">Jan N. Safer</name><name sortKey="Sage, Jacob I" sort="Sage, Jacob I" uniqKey="Sage J" first="Jacob I." last="Sage">Jacob I. Sage</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004598 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Checkpoint/biblio.hfd -nk 004598 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Istex
|étape= Checkpoint
|type= RBID
|clé= ISTEX:BABB09EE0A410D78CD6666F45B6F8EBCD6B6AAE8
|texte= Computed tomographic findings in progressive supranuclear palsy: Correlation with clinical grade
}}
| This area was generated with Dilib version V0.6.23. |  |