Treatment of periodic limb movements in sleep with selegiline HCl
Identifieur interne : 002B41 ( Istex/Checkpoint ); précédent : 002B40; suivant : 002B42Treatment of periodic limb movements in sleep with selegiline HCl
Auteurs : Manavdeep Grewal [Canada] ; Raed Hawa [Canada] ; Colin Shapiro [Canada]Source :
- Movement Disorders [ 0885-3185 ] ; 2002-03.
English descriptors
Abstract
Thirty‐one patients undergoing treatment with selegiline HCl for periodic limb movements in sleep (PLMS) were examined with respect to specific sleep composition in a retrospective study. Pre‐ and post‐treatment overnight polysomnographs revealed a highly significant decrease in the number of PLMS per hour of total sleep time (P < 0.0005). The alerting effect associated with selegiline was not found to have significant effect on patients' sleep efficiency or sleep‐onset latency (P > 0.10). As controversy continues regarding the medicated treatment of PLMS, our findings with selegiline point to an alternative for clinicians to consider. © 2002 Movement Disorder Society
Url:
DOI: 10.1002/mds.10082
Affiliations:
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