Topiramate therapy for paroxysmal kinesigenic choreoathetosis
Identifieur interne : 002105 ( Istex/Checkpoint ); précédent : 002104; suivant : 002106Topiramate therapy for paroxysmal kinesigenic choreoathetosis
Auteurs : Yuan-Gui Huang [République populaire de Chine] ; Yun-Chun Chen [République populaire de Chine] ; Fang Du [République populaire de Chine] ; Rui Li [République populaire de Chine] ; Ge-Lin Xu [République populaire de Chine] ; Wen Jiang [République populaire de Chine] ; Jing Huang [République populaire de Chine]Source :
- Movement Disorders [ 0885-3185 ] ; 2005-01.
English descriptors
Abstract
We observed the clinical efficacy of topiramate for paroxysmal kinesigenic choreoathetosis (PKC). Topiramate was administered as a monotherapy with titrated dosages to 8 patients with PKC. Target daily dose of topiramate was 100 to 200 mg; the follow‐up period ranged from 8 months to 2 years. All of the patients became attack‐free, and side effects were mild. The results show that topiramate is effective as a monotherapy for treating patients with PKC. The response to topiramate indicates that the disease may be caused by an ion channel defect. © 2004 Movement Disorder Society
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DOI: 10.1002/mds.20283
Affiliations:
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2005-01">2005-01</date><biblScope unit="vol">20</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="75">75</biblScope><biblScope unit="page" to="77">77</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">804AD4AFE2AAFFCBCA39215F747DB3FF8E32163A</idno><idno type="DOI">10.1002/mds.20283</idno><idno type="ArticleID">MDS20283</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>paroxysmal kinesigenic choreoathetosis</term><term>topiramate</term><term>treatment</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We observed the clinical efficacy of topiramate for paroxysmal kinesigenic choreoathetosis (PKC). Topiramate was administered as a monotherapy with titrated dosages to 8 patients with PKC. Target daily dose of topiramate was 100 to 200 mg; the follow‐up period ranged from 8 months to 2 years. All of the patients became attack‐free, and side effects were mild. The results show that topiramate is effective as a monotherapy for treating patients with PKC. The response to topiramate indicates that the disease may be caused by an ion channel defect. © 2004 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Huang, Yuan Ui" sort="Huang, Yuan Ui" uniqKey="Huang Y" first="Yuan-Gui" last="Huang">Yuan-Gui Huang</name></noRegion><name sortKey="Chen, Yun Hun" sort="Chen, Yun Hun" uniqKey="Chen Y" first="Yun-Chun" last="Chen">Yun-Chun Chen</name><name sortKey="Du, Fang" sort="Du, Fang" uniqKey="Du F" first="Fang" last="Du">Fang Du</name><name sortKey="Huang, Jing" sort="Huang, Jing" uniqKey="Huang J" first="Jing" last="Huang">Jing Huang</name><name sortKey="Jiang, Wen" sort="Jiang, Wen" uniqKey="Jiang W" first="Wen" last="Jiang">Wen Jiang</name><name sortKey="Li, Rui" sort="Li, Rui" uniqKey="Li R" first="Rui" last="Li">Rui Li</name><name sortKey="Xu, Ge In" sort="Xu, Ge In" uniqKey="Xu G" first="Ge-Lin" last="Xu">Ge-Lin Xu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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