Age at menopause predicts age at onset of Parkinson's disease
Identifieur interne : 002063 ( Istex/Checkpoint ); précédent : 002062; suivant : 002064Age at menopause predicts age at onset of Parkinson's disease
Auteurs : Paolo Ragonese [Italie] ; Marco D'Amelio [Italie] ; Graziella Callari [Italie] ; Giuseppe Salemi [Italie] ; Letterio Morgante [Italie] ; Giovanni Savettieri [Italie]Source :
- Movement Disorders [ 0885-3185 ] ; 2006-12.
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Abstract
We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD. © 2006 Movement Disorder Society
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DOI: 10.1002/mds.21127
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<front><div type="abstract" xml:lang="en">We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD. © 2006 Movement Disorder Society</div>
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