Movement Disorders (revue)

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Age at menopause predicts age at onset of Parkinson's disease

Identifieur interne : 002063 ( Istex/Checkpoint ); précédent : 002062; suivant : 002064

Age at menopause predicts age at onset of Parkinson's disease

Auteurs : Paolo Ragonese [Italie] ; Marco D'Amelio [Italie] ; Graziella Callari [Italie] ; Giuseppe Salemi [Italie] ; Letterio Morgante [Italie] ; Giovanni Savettieri [Italie]

Source :

RBID : ISTEX:34629850DF799A2469DB3FD0FA4F87960D12762D

English descriptors

Abstract

We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD. © 2006 Movement Disorder Society

Url:
DOI: 10.1002/mds.21127


Affiliations:


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ISTEX:34629850DF799A2469DB3FD0FA4F87960D12762D

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<title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
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<div type="abstract" xml:lang="en">We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD. © 2006 Movement Disorder Society</div>
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