Movement Disorders (revue)

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Hypoperfusion of the auditory and prefrontal cortices in Parkinsonian patients with verbal hallucinations

Identifieur interne : 001E55 ( Istex/Checkpoint ); précédent : 001E54; suivant : 001E56

Hypoperfusion of the auditory and prefrontal cortices in Parkinsonian patients with verbal hallucinations

Auteurs : Hideaki Matsui [Japon] ; Kazuto Nishinaka [Japon] ; Masaya Oda [Japon] ; Narihiro Hara [Japon] ; Kenichi Komatsu [Japon] ; Tamotsu Kubori [Japon] ; Fukashi Udaka [Japon]

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RBID : ISTEX:EDDCC12E824BC40BB60241B9FEA64AA58B9291BA

English descriptors

Abstract

We examined patients with and without auditory hallucinations, using n‐isopropyl‐p‐[123I]iodoamphetamine single photon emission computed tomographic imaging. We assessed verbal hallucinations in the present study: patients with nonverbal auditory hallucinations were excluded. A total of 11 patients with verbal and visual hallucinations and 17 patients with visual hallucinations only were enrolled. Patients with both verbal and visual hallucinations revealed significant hypoperfusion in the bilateral prefrontal cortex and right superior temporal gyrus compared to patients with visual hallucinations only. There were no significant hyperperfusion in patients with verbal plus visual hallucinations. These results may support the release hallucination theory in verbal hallucinations of Parkinson's disease, although another explanations may be more appropriate and further studies are required. © 2006 Movement Disorder Society

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DOI: 10.1002/mds.21147


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ISTEX:EDDCC12E824BC40BB60241B9FEA64AA58B9291BA

Le document en format XML

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