Severe hypokinesis caused by paraneoplastic anti‐Ma2 encephalitis associated with bilateral intratubular germ‐cell neoplasm of the testes
Identifieur interne : 001692 ( Istex/Checkpoint ); précédent : 001691; suivant : 001693Severe hypokinesis caused by paraneoplastic anti‐Ma2 encephalitis associated with bilateral intratubular germ‐cell neoplasm of the testes
Auteurs : Lumine Matsumoto [Japon] ; Tomotaka Yamamoto [Japon] ; Mana Higashihara [Japon] ; Izumi Sugimoto [Japon] ; Hisatomo Kowa [Japon] ; Junji Shibahara [Japon] ; Koichiro Nakamura [Japon] ; Jun Shimizu [Japon] ; Yoshikazu Ugawa [Japon] ; Jun Goto [Japon] ; Josep Dalmau [États-Unis] ; Shoji Tsuji [Japon]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-04-15.
English descriptors
- KwdEn :
Abstract
We report a 40‐year‐old man with severe hypokinesis as paraneoplastic manifestation of a microscopic “carcinoma in situ” of the testis. The young age of the patient, along with progressive neurologic deterioration, detection of anti‐Ma2 antibodies, and ultrasound findings of bilateral microcalcifications, led to bilateral orchiectomy, revealing the tumor in both testes. After orchiectomy, neurological symptoms stabilized, but the patient eventually died of systemic complications caused by his severe neurological deficits. Anti‐Ma2 paraneoplastic encephalitis should be considered in patients with severe hypokinesis, and intensive investigation and aggressive approach to treatment is encouraged to prevent progression of the neurological deficits. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.21314
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
ISTEX:5EB5E12C59D842A3A97211F6ABC9D543D07BD0CALe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Severe hypokinesis caused by paraneoplastic anti‐Ma2 encephalitis associated with bilateral intratubular germ‐cell neoplasm of the testes</title>
<author><name sortKey="Matsumoto, Lumine" sort="Matsumoto, Lumine" uniqKey="Matsumoto L" first="Lumine" last="Matsumoto">Lumine Matsumoto</name>
</author>
<author><name sortKey="Yamamoto, Tomotaka" sort="Yamamoto, Tomotaka" uniqKey="Yamamoto T" first="Tomotaka" last="Yamamoto">Tomotaka Yamamoto</name>
</author>
<author><name sortKey="Higashihara, Mana" sort="Higashihara, Mana" uniqKey="Higashihara M" first="Mana" last="Higashihara">Mana Higashihara</name>
</author>
<author><name sortKey="Sugimoto, Izumi" sort="Sugimoto, Izumi" uniqKey="Sugimoto I" first="Izumi" last="Sugimoto">Izumi Sugimoto</name>
</author>
<author><name sortKey="Kowa, Hisatomo" sort="Kowa, Hisatomo" uniqKey="Kowa H" first="Hisatomo" last="Kowa">Hisatomo Kowa</name>
</author>
<author><name sortKey="Shibahara, Junji" sort="Shibahara, Junji" uniqKey="Shibahara J" first="Junji" last="Shibahara">Junji Shibahara</name>
</author>
<author><name sortKey="Nakamura, Koichiro" sort="Nakamura, Koichiro" uniqKey="Nakamura K" first="Koichiro" last="Nakamura">Koichiro Nakamura</name>
</author>
<author><name sortKey="Shimizu, Jun" sort="Shimizu, Jun" uniqKey="Shimizu J" first="Jun" last="Shimizu">Jun Shimizu</name>
</author>
<author><name sortKey="Ugawa, Yoshikazu" sort="Ugawa, Yoshikazu" uniqKey="Ugawa Y" first="Yoshikazu" last="Ugawa">Yoshikazu Ugawa</name>
</author>
<author><name sortKey="Goto, Jun" sort="Goto, Jun" uniqKey="Goto J" first="Jun" last="Goto">Jun Goto</name>
</author>
<author><name sortKey="Dalmau, Josep" sort="Dalmau, Josep" uniqKey="Dalmau J" first="Josep" last="Dalmau">Josep Dalmau</name>
</author>
<author><name sortKey="Tsuji, Shoji" sort="Tsuji, Shoji" uniqKey="Tsuji S" first="Shoji" last="Tsuji">Shoji Tsuji</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:5EB5E12C59D842A3A97211F6ABC9D543D07BD0CA</idno>
<date when="2007" year="2007">2007</date>
<idno type="doi">10.1002/mds.21314</idno>
<idno type="url">https://api.istex.fr/document/5EB5E12C59D842A3A97211F6ABC9D543D07BD0CA/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">003403</idno>
<idno type="wicri:Area/Istex/Curation">003403</idno>
<idno type="wicri:Area/Istex/Checkpoint">001692</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Severe hypokinesis caused by paraneoplastic anti‐Ma2 encephalitis associated with bilateral intratubular germ‐cell neoplasm of the testes</title>
<author><name sortKey="Matsumoto, Lumine" sort="Matsumoto, Lumine" uniqKey="Matsumoto L" first="Lumine" last="Matsumoto">Lumine Matsumoto</name>
<affiliation wicri:level="3"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, The University of Tokyo, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yamamoto, Tomotaka" sort="Yamamoto, Tomotaka" uniqKey="Yamamoto T" first="Tomotaka" last="Yamamoto">Tomotaka Yamamoto</name>
<affiliation wicri:level="3"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, The University of Tokyo, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Higashihara, Mana" sort="Higashihara, Mana" uniqKey="Higashihara M" first="Mana" last="Higashihara">Mana Higashihara</name>
<affiliation wicri:level="3"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, The University of Tokyo, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sugimoto, Izumi" sort="Sugimoto, Izumi" uniqKey="Sugimoto I" first="Izumi" last="Sugimoto">Izumi Sugimoto</name>
<affiliation wicri:level="3"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, The University of Tokyo, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kowa, Hisatomo" sort="Kowa, Hisatomo" uniqKey="Kowa H" first="Hisatomo" last="Kowa">Hisatomo Kowa</name>
<affiliation wicri:level="3"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, The University of Tokyo, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Shibahara, Junji" sort="Shibahara, Junji" uniqKey="Shibahara J" first="Junji" last="Shibahara">Junji Shibahara</name>
<affiliation wicri:level="3"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Pathology, The University of Tokyo, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nakamura, Koichiro" sort="Nakamura, Koichiro" uniqKey="Nakamura K" first="Koichiro" last="Nakamura">Koichiro Nakamura</name>
<affiliation wicri:level="3"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, The University of Tokyo, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Shimizu, Jun" sort="Shimizu, Jun" uniqKey="Shimizu J" first="Jun" last="Shimizu">Jun Shimizu</name>
<affiliation wicri:level="3"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, The University of Tokyo, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ugawa, Yoshikazu" sort="Ugawa, Yoshikazu" uniqKey="Ugawa Y" first="Yoshikazu" last="Ugawa">Yoshikazu Ugawa</name>
<affiliation wicri:level="3"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, The University of Tokyo, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Goto, Jun" sort="Goto, Jun" uniqKey="Goto J" first="Jun" last="Goto">Jun Goto</name>
<affiliation wicri:level="3"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, The University of Tokyo, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dalmau, Josep" sort="Dalmau, Josep" uniqKey="Dalmau J" first="Josep" last="Dalmau">Josep Dalmau</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology (Division Neuro‐Oncology), University of Pennsylvania, Philadelphia, Pennsylvania</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tsuji, Shoji" sort="Tsuji, Shoji" uniqKey="Tsuji S" first="Shoji" last="Tsuji">Shoji Tsuji</name>
<affiliation wicri:level="3"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, The University of Tokyo, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2007-04-15">2007-04-15</date>
<biblScope unit="vol">22</biblScope>
<biblScope unit="issue">5</biblScope>
<biblScope unit="page" from="728">728</biblScope>
<biblScope unit="page" to="731">731</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">5EB5E12C59D842A3A97211F6ABC9D543D07BD0CA</idno>
<idno type="DOI">10.1002/mds.21314</idno>
<idno type="ArticleID">MDS21314</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinsonism</term>
<term>anti‐Ma2 paraneoplastic encephalitis</term>
<term>hypokinesis</term>
<term>intratubular germ‐cell neoplasia</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">We report a 40‐year‐old man with severe hypokinesis as paraneoplastic manifestation of a microscopic “carcinoma in situ” of the testis. The young age of the patient, along with progressive neurologic deterioration, detection of anti‐Ma2 antibodies, and ultrasound findings of bilateral microcalcifications, led to bilateral orchiectomy, revealing the tumor in both testes. After orchiectomy, neurological symptoms stabilized, but the patient eventually died of systemic complications caused by his severe neurological deficits. Anti‐Ma2 paraneoplastic encephalitis should be considered in patients with severe hypokinesis, and intensive investigation and aggressive approach to treatment is encouraged to prevent progression of the neurological deficits. © 2006 Movement Disorder Society</div>
</front>
</TEI>
<affiliations><list><country><li>Japon</li>
<li>États-Unis</li>
</country>
<region><li>Pennsylvanie</li>
</region>
<settlement><li>Tokyo</li>
</settlement>
</list>
<tree><country name="Japon"><noRegion><name sortKey="Matsumoto, Lumine" sort="Matsumoto, Lumine" uniqKey="Matsumoto L" first="Lumine" last="Matsumoto">Lumine Matsumoto</name>
</noRegion>
<name sortKey="Goto, Jun" sort="Goto, Jun" uniqKey="Goto J" first="Jun" last="Goto">Jun Goto</name>
<name sortKey="Higashihara, Mana" sort="Higashihara, Mana" uniqKey="Higashihara M" first="Mana" last="Higashihara">Mana Higashihara</name>
<name sortKey="Kowa, Hisatomo" sort="Kowa, Hisatomo" uniqKey="Kowa H" first="Hisatomo" last="Kowa">Hisatomo Kowa</name>
<name sortKey="Nakamura, Koichiro" sort="Nakamura, Koichiro" uniqKey="Nakamura K" first="Koichiro" last="Nakamura">Koichiro Nakamura</name>
<name sortKey="Shibahara, Junji" sort="Shibahara, Junji" uniqKey="Shibahara J" first="Junji" last="Shibahara">Junji Shibahara</name>
<name sortKey="Shimizu, Jun" sort="Shimizu, Jun" uniqKey="Shimizu J" first="Jun" last="Shimizu">Jun Shimizu</name>
<name sortKey="Sugimoto, Izumi" sort="Sugimoto, Izumi" uniqKey="Sugimoto I" first="Izumi" last="Sugimoto">Izumi Sugimoto</name>
<name sortKey="Tsuji, Shoji" sort="Tsuji, Shoji" uniqKey="Tsuji S" first="Shoji" last="Tsuji">Shoji Tsuji</name>
<name sortKey="Ugawa, Yoshikazu" sort="Ugawa, Yoshikazu" uniqKey="Ugawa Y" first="Yoshikazu" last="Ugawa">Yoshikazu Ugawa</name>
<name sortKey="Yamamoto, Tomotaka" sort="Yamamoto, Tomotaka" uniqKey="Yamamoto T" first="Tomotaka" last="Yamamoto">Tomotaka Yamamoto</name>
</country>
<country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Dalmau, Josep" sort="Dalmau, Josep" uniqKey="Dalmau J" first="Josep" last="Dalmau">Josep Dalmau</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001692 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Checkpoint/biblio.hfd -nk 001692 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Istex |étape= Checkpoint |type= RBID |clé= ISTEX:5EB5E12C59D842A3A97211F6ABC9D543D07BD0CA |texte= Severe hypokinesis caused by paraneoplastic anti‐Ma2 encephalitis associated with bilateral intratubular germ‐cell neoplasm of the testes }}
![]() | This area was generated with Dilib version V0.6.23. | ![]() |