Survival in multiple system atrophy
Identifieur interne : 001168 ( Istex/Checkpoint ); précédent : 001167; suivant : 001169Survival in multiple system atrophy
Auteurs : Anette Schrag [Royaume-Uni] ; Gregor K. Wenning [Autriche] ; Niall Quinn [Royaume-Uni] ; Yoav Ben-Shlomo [Royaume-Uni]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-01-30.
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Abstract
We here report survival in patients with multiple system atrophy (MSA) in a large, prospectively studied group of patients with MSA. Eighty‐five of 100 patients were known to have died. Three patients were rediagnosed as having PD. Twenty‐four patients came to autopsy, which showed MSA in 22 and idiopathic Parkinson's disease in 2. The median survival time was 8.6 and 7.3 years for men and women, respectively (hazard ratio for women was 1.49, 95% CI 0.97–2.31, P = 0.07). Except for rediagnosis as PD, no predictive factors for better survival could be identified. These data confirm the relatively poor prognosis of MSA of less than 9 years on average. © 2007 Movement Disorder Society
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DOI: 10.1002/mds.21839
Affiliations:
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<front><div type="abstract" xml:lang="en">We here report survival in patients with multiple system atrophy (MSA) in a large, prospectively studied group of patients with MSA. Eighty‐five of 100 patients were known to have died. Three patients were rediagnosed as having PD. Twenty‐four patients came to autopsy, which showed MSA in 22 and idiopathic Parkinson's disease in 2. The median survival time was 8.6 and 7.3 years for men and women, respectively (hazard ratio for women was 1.49, 95% CI 0.97–2.31, P = 0.07). Except for rediagnosis as PD, no predictive factors for better survival could be identified. These data confirm the relatively poor prognosis of MSA of less than 9 years on average. © 2007 Movement Disorder Society</div>
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