The prodromal phase of sporadic Parkinson's disease: Does it exist and if so how long is it?
Identifieur interne : 001132 ( Istex/Checkpoint ); précédent : 001131; suivant : 001133The prodromal phase of sporadic Parkinson's disease: Does it exist and if so how long is it?
Auteurs : Christopher H. Hawkes [Royaume-Uni]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-10-15.
English descriptors
Abstract
It is frequently assumed that idiopathic Parkinson's disease starts with several nonmotor symptoms and signs, but the evidence for this stage in the disease process is of variable quality. This review evaluates the more robust prospective or pathologically confirmed publications to establish whether there is a premotor period and if so what is its duration. The most informative studies are considered to be those concerned with olfaction, dysautonomia, and sleep disorder. Estimates for the duration of the prodromal phase vary from months to decades. It is concluded that there probably is an early phase in the disease where a variety of nonmotor features develop, but the sequence and time of onset of such features is not well established. © 2008 Movement Disorder Society
Url:
DOI: 10.1002/mds.22242
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
ISTEX:0A0E5233BC029ED2E1BC3FAB605961AC59E2D1ECLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">The prodromal phase of sporadic Parkinson's disease: Does it exist and if so how long is it?</title>
<author><name sortKey="Hawkes, Christopher H" sort="Hawkes, Christopher H" uniqKey="Hawkes C" first="Christopher H." last="Hawkes">Christopher H. Hawkes</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:0A0E5233BC029ED2E1BC3FAB605961AC59E2D1EC</idno>
<date when="2008" year="2008">2008</date>
<idno type="doi">10.1002/mds.22242</idno>
<idno type="url">https://api.istex.fr/document/0A0E5233BC029ED2E1BC3FAB605961AC59E2D1EC/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001213</idno>
<idno type="wicri:Area/Istex/Curation">001213</idno>
<idno type="wicri:Area/Istex/Checkpoint">001132</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">The prodromal phase of sporadic Parkinson's disease: Does it exist and if so how long is it?</title>
<author><name sortKey="Hawkes, Christopher H" sort="Hawkes, Christopher H" uniqKey="Hawkes C" first="Christopher H." last="Hawkes">Christopher H. Hawkes</name>
<affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Neuroscience Centre, Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2008-10-15">2008-10-15</date>
<biblScope unit="vol">23</biblScope>
<biblScope unit="issue">13</biblScope>
<biblScope unit="page" from="1799">1799</biblScope>
<biblScope unit="page" to="1807">1807</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">0A0E5233BC029ED2E1BC3FAB605961AC59E2D1EC</idno>
<idno type="DOI">10.1002/mds.22242</idno>
<idno type="ArticleID">MDS22242</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Braak staging</term>
<term>Parkinson's disease</term>
<term>premotor phase</term>
<term>prodromal period</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">It is frequently assumed that idiopathic Parkinson's disease starts with several nonmotor symptoms and signs, but the evidence for this stage in the disease process is of variable quality. This review evaluates the more robust prospective or pathologically confirmed publications to establish whether there is a premotor period and if so what is its duration. The most informative studies are considered to be those concerned with olfaction, dysautonomia, and sleep disorder. Estimates for the duration of the prodromal phase vary from months to decades. It is concluded that there probably is an early phase in the disease where a variety of nonmotor features develop, but the sequence and time of onset of such features is not well established. © 2008 Movement Disorder Society</div>
</front>
</TEI>
<affiliations><list><country><li>Royaume-Uni</li>
</country>
<region><li>Angleterre</li>
<li>Grand Londres</li>
</region>
<settlement><li>Londres</li>
</settlement>
</list>
<tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Hawkes, Christopher H" sort="Hawkes, Christopher H" uniqKey="Hawkes C" first="Christopher H." last="Hawkes">Christopher H. Hawkes</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001132 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Checkpoint/biblio.hfd -nk 001132 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Istex |étape= Checkpoint |type= RBID |clé= ISTEX:0A0E5233BC029ED2E1BC3FAB605961AC59E2D1EC |texte= The prodromal phase of sporadic Parkinson's disease: Does it exist and if so how long is it? }}
![]() | This area was generated with Dilib version V0.6.23. | ![]() |