Gait and balance disorders in Parkinson's disease: impaired active braking of the fall of centre of gravity.
Identifieur interne : 000028 ( Hal/Corpus ); précédent : 000027; suivant : 000029Gait and balance disorders in Parkinson's disease: impaired active braking of the fall of centre of gravity.
Auteurs : Nathalie Chastan ; Manh Cuong Do ; Fabrice Bonneville ; Frédéric Torny ; Frédéric Bloch ; G W Max Westby ; Didier Dormont ; Yves Agid ; Marie-Laure WelterSource :
- Movement Disorders [ 0885-3185 ] ; 2009-01-30.
Abstract
Gait and balance disorders are common in Parkinson's disease (PD), but its pathophysiology is still poorly understood. Step length, antero-posterior, and vertical velocities of the center of gravity (CG) during gait initiation were analyzed in 32 controls and 32 PD patients, with and without levodopa, using a force platform. Brain volumes and mesencephalic surface area were measured in PD patients. During the swing limb period, controls showed a fall in the CG, which was reversed before foot-contact indicating active braking of the CG fall. In PD patients, without levodopa, step length and velocity were significantly reduced and no braking occurred before foot-contact in 22 patients. With levodopa, step length and velocity increased in all patients and 7 patients improved their braking capacity. PD patients with normal braking (n = 17) had significantly lower gait and balance disorder scores and higher normalized-mesencephalic surface areas compared to patients with impaired braking (n = 15). The decreased step length and velocity, characteristic of PD, mainly result from degeneration of central dopaminergic systems. The markedly decreased braking capacity observed in half the PD patients contributes to their gait disorders and postural instability, perhaps as a result of nondopaminergic lesions, possibly at the mesencephalic level.
Url:
DOI: 10.1002/mds.22269
Links to Exploration step
Hal:hal-00805424Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Gait and balance disorders in Parkinson's disease: impaired active braking of the fall of centre of gravity.</title><author><name sortKey="Chastan, Nathalie" sort="Chastan, Nathalie" uniqKey="Chastan N" first="Nathalie" last="Chastan">Nathalie Chastan</name><affiliation><hal:affiliation type="laboratory" xml:id="struct-115097" status="VALID"><orgName>Service de neurophysiologie</orgName><desc><address><country key="FR"></country></address></desc><listRelation><relation active="#struct-300147" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-300147" type="direct"><org type="institution" xml:id="struct-300147" status="VALID"><orgName>CHU Rouen</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation></affiliation></author><author><name sortKey="Do, Manh Cuong" sort="Do, Manh Cuong" uniqKey="Do M" first="Manh Cuong" last="Do">Manh Cuong Do</name></author><author><name sortKey="Bonneville, Fabrice" sort="Bonneville, Fabrice" uniqKey="Bonneville F" first="Fabrice" last="Bonneville">Fabrice Bonneville</name><affiliation><hal:affiliation type="laboratory" xml:id="struct-205419" status="INCOMING"><orgName>Service de neuroradiologie</orgName><desc><address><addrLine>Hôpital Rangueil Toulouse</addrLine><country key="FR"></country></address></desc><listRelation><relation active="#struct-300075" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-300075" type="direct"><org type="institution" xml:id="struct-300075" status="VALID"><orgName>CHU Toulouse [Toulouse]</orgName><desc><address><addrLine>330 Avenue de Grande Bretagne, TSA 40031, 31059 Toulouse Cedex 09</addrLine><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation></affiliation></author><author><name sortKey="Torny, Frederic" sort="Torny, Frederic" uniqKey="Torny F" first="Frédéric" last="Torny">Frédéric Torny</name></author><author><name sortKey="Bloch, Frederic" sort="Bloch, Frederic" uniqKey="Bloch F" first="Frédéric" last="Bloch">Frédéric Bloch</name></author><author><name sortKey="Westby, G W Max" sort="Westby, G W Max" uniqKey="Westby G" first="G W Max" last="Westby">G W Max Westby</name></author><author><name sortKey="Dormont, Didier" sort="Dormont, Didier" uniqKey="Dormont D" first="Didier" last="Dormont">Didier Dormont</name><affiliation><hal:affiliation type="laboratory" xml:id="struct-41020" status="VALID"><orgName>Service de neuro-radiologie</orgName><desc><address><addrLine>47-83, boulevard de l'Hôpital 75651 PARIS Cedex 13</addrLine><country key="FR"></country></address></desc><listRelation><relation active="#struct-93591" type="direct"></relation><relation active="#struct-300068" type="direct"></relation><relation active="#struct-300887" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="VALID"><orgName>Université Pierre et Marie Curie - Paris 6</orgName><orgName type="acronym">UPMC</orgName><desc><address><addrLine>4 place Jussieu - 75005 Paris</addrLine><country key="FR"></country></address><ref type="url">http://www.upmc.fr/</ref></desc></org></tutelle><tutelle active="#struct-300068" type="direct"><org type="institution" xml:id="struct-300068" status="VALID"><orgName>Assistance publique - Hôpitaux de Paris (AP-HP)</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle><tutelle active="#struct-300887" type="direct"><org type="institution" xml:id="struct-300887" status="INCOMING"><orgName>Hôpital Pitié-Salpêtrière</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation></affiliation></author><author><name sortKey="Agid, Yves" sort="Agid, Yves" uniqKey="Agid Y" first="Yves" last="Agid">Yves Agid</name><affiliation><hal:affiliation type="laboratory" xml:id="struct-43171" status="VALID"><orgName>Fédération des Maladies du Système Nerveux</orgName><desc><address><addrLine>47-83, boulevard de l'Hôpital - 75651 PARIS Cedex 13</addrLine><country key="FR"></country></address></desc><listRelation><relation active="#struct-300068" type="direct"></relation><relation active="#struct-300887" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-300068" type="direct"><org type="institution" xml:id="struct-300068" status="VALID"><orgName>Assistance publique - Hôpitaux de Paris (AP-HP)</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle><tutelle active="#struct-300887" type="direct"><org type="institution" xml:id="struct-300887" status="INCOMING"><orgName>Hôpital Pitié-Salpêtrière</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation></affiliation></author><author><name sortKey="Welter, Marie Laure" sort="Welter, Marie Laure" uniqKey="Welter M" first="Marie-Laure" last="Welter">Marie-Laure Welter</name><affiliation><hal:affiliation type="laboratory" xml:id="struct-81470" status="OLD"><orgName>Centre de Recherche de l'Institut du Cerveau et de la Moelle épinière [Paris]</orgName><orgName type="acronym">CRICM</orgName><desc><address><addrLine>GH Pitié-Salpêtrière 47, boulevard de l'Hôpital 75651 Paris cedex 13</addrLine><country key="FR"></country></address><ref type="url">http://www.cricm.upmc.fr/</ref></desc><listRelation><relation active="#struct-93591" type="direct"></relation><relation name="U975" active="#struct-300002" type="direct"></relation><relation name="UMR7225" active="#struct-441569" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="VALID"><orgName>Université Pierre et Marie Curie - Paris 6</orgName><orgName type="acronym">UPMC</orgName><desc><address><addrLine>4 place Jussieu - 75005 Paris</addrLine><country key="FR"></country></address><ref type="url">http://www.upmc.fr/</ref></desc></org></tutelle><tutelle name="U975" active="#struct-300002" type="direct"><org type="institution" xml:id="struct-300002" status="VALID"><orgName>INSERM</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle><tutelle name="UMR7225" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">HAL</idno><idno type="RBID">Hal:hal-00805424</idno><idno type="halId">hal-00805424</idno><idno type="halUri">https://hal.inria.fr/hal-00805424</idno><idno type="url">https://hal.inria.fr/hal-00805424</idno><idno type="doi">10.1002/mds.22269</idno><date when="2009-01-30">2009-01-30</date><idno type="wicri:Area/Hal/Corpus">000028</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Gait and balance disorders in Parkinson's disease: impaired active braking of the fall of centre of gravity.</title><author><name sortKey="Chastan, Nathalie" sort="Chastan, Nathalie" uniqKey="Chastan N" first="Nathalie" last="Chastan">Nathalie Chastan</name><affiliation><hal:affiliation type="laboratory" xml:id="struct-115097" status="VALID"><orgName>Service de neurophysiologie</orgName><desc><address><country key="FR"></country></address></desc><listRelation><relation active="#struct-300147" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-300147" type="direct"><org type="institution" xml:id="struct-300147" status="VALID"><orgName>CHU Rouen</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation></affiliation></author><author><name sortKey="Do, Manh Cuong" sort="Do, Manh Cuong" uniqKey="Do M" first="Manh Cuong" last="Do">Manh Cuong Do</name></author><author><name sortKey="Bonneville, Fabrice" sort="Bonneville, Fabrice" uniqKey="Bonneville F" first="Fabrice" last="Bonneville">Fabrice Bonneville</name><affiliation><hal:affiliation type="laboratory" xml:id="struct-205419" status="INCOMING"><orgName>Service de neuroradiologie</orgName><desc><address><addrLine>Hôpital Rangueil Toulouse</addrLine><country key="FR"></country></address></desc><listRelation><relation active="#struct-300075" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-300075" type="direct"><org type="institution" xml:id="struct-300075" status="VALID"><orgName>CHU Toulouse [Toulouse]</orgName><desc><address><addrLine>330 Avenue de Grande Bretagne, TSA 40031, 31059 Toulouse Cedex 09</addrLine><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation></affiliation></author><author><name sortKey="Torny, Frederic" sort="Torny, Frederic" uniqKey="Torny F" first="Frédéric" last="Torny">Frédéric Torny</name></author><author><name sortKey="Bloch, Frederic" sort="Bloch, Frederic" uniqKey="Bloch F" first="Frédéric" last="Bloch">Frédéric Bloch</name></author><author><name sortKey="Westby, G W Max" sort="Westby, G W Max" uniqKey="Westby G" first="G W Max" last="Westby">G W Max Westby</name></author><author><name sortKey="Dormont, Didier" sort="Dormont, Didier" uniqKey="Dormont D" first="Didier" last="Dormont">Didier Dormont</name><affiliation><hal:affiliation type="laboratory" xml:id="struct-41020" status="VALID"><orgName>Service de neuro-radiologie</orgName><desc><address><addrLine>47-83, boulevard de l'Hôpital 75651 PARIS Cedex 13</addrLine><country key="FR"></country></address></desc><listRelation><relation active="#struct-93591" type="direct"></relation><relation active="#struct-300068" type="direct"></relation><relation active="#struct-300887" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="VALID"><orgName>Université Pierre et Marie Curie - Paris 6</orgName><orgName type="acronym">UPMC</orgName><desc><address><addrLine>4 place Jussieu - 75005 Paris</addrLine><country key="FR"></country></address><ref type="url">http://www.upmc.fr/</ref></desc></org></tutelle><tutelle active="#struct-300068" type="direct"><org type="institution" xml:id="struct-300068" status="VALID"><orgName>Assistance publique - Hôpitaux de Paris (AP-HP)</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle><tutelle active="#struct-300887" type="direct"><org type="institution" xml:id="struct-300887" status="INCOMING"><orgName>Hôpital Pitié-Salpêtrière</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation></affiliation></author><author><name sortKey="Agid, Yves" sort="Agid, Yves" uniqKey="Agid Y" first="Yves" last="Agid">Yves Agid</name><affiliation><hal:affiliation type="laboratory" xml:id="struct-43171" status="VALID"><orgName>Fédération des Maladies du Système Nerveux</orgName><desc><address><addrLine>47-83, boulevard de l'Hôpital - 75651 PARIS Cedex 13</addrLine><country key="FR"></country></address></desc><listRelation><relation active="#struct-300068" type="direct"></relation><relation active="#struct-300887" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-300068" type="direct"><org type="institution" xml:id="struct-300068" status="VALID"><orgName>Assistance publique - Hôpitaux de Paris (AP-HP)</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle><tutelle active="#struct-300887" type="direct"><org type="institution" xml:id="struct-300887" status="INCOMING"><orgName>Hôpital Pitié-Salpêtrière</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation></affiliation></author><author><name sortKey="Welter, Marie Laure" sort="Welter, Marie Laure" uniqKey="Welter M" first="Marie-Laure" last="Welter">Marie-Laure Welter</name><affiliation><hal:affiliation type="laboratory" xml:id="struct-81470" status="OLD"><orgName>Centre de Recherche de l'Institut du Cerveau et de la Moelle épinière [Paris]</orgName><orgName type="acronym">CRICM</orgName><desc><address><addrLine>GH Pitié-Salpêtrière 47, boulevard de l'Hôpital 75651 Paris cedex 13</addrLine><country key="FR"></country></address><ref type="url">http://www.cricm.upmc.fr/</ref></desc><listRelation><relation active="#struct-93591" type="direct"></relation><relation name="U975" active="#struct-300002" type="direct"></relation><relation name="UMR7225" active="#struct-441569" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="VALID"><orgName>Université Pierre et Marie Curie - Paris 6</orgName><orgName type="acronym">UPMC</orgName><desc><address><addrLine>4 place Jussieu - 75005 Paris</addrLine><country key="FR"></country></address><ref type="url">http://www.upmc.fr/</ref></desc></org></tutelle><tutelle name="U975" active="#struct-300002" type="direct"><org type="institution" xml:id="struct-300002" status="VALID"><orgName>INSERM</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle><tutelle name="UMR7225" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="IdRef">02636817X</idno><idno type="ISNI">0000000122597504</idno><orgName>Centre National de la Recherche Scientifique</orgName><orgName type="acronym">CNRS</orgName><date type="start">1939-10-19</date><desc><address><country key="FR"></country></address><ref type="url">http://www.cnrs.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation></affiliation></author></analytic><idno type="DOI">10.1002/mds.22269</idno><series><title level="j">Movement Disorders</title><idno type="ISSN">0885-3185</idno><imprint><date type="datePub">2009-01-30</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Gait and balance disorders are common in Parkinson's disease (PD), but its pathophysiology is still poorly understood. Step length, antero-posterior, and vertical velocities of the center of gravity (CG) during gait initiation were analyzed in 32 controls and 32 PD patients, with and without levodopa, using a force platform. Brain volumes and mesencephalic surface area were measured in PD patients. During the swing limb period, controls showed a fall in the CG, which was reversed before foot-contact indicating active braking of the CG fall. In PD patients, without levodopa, step length and velocity were significantly reduced and no braking occurred before foot-contact in 22 patients. With levodopa, step length and velocity increased in all patients and 7 patients improved their braking capacity. PD patients with normal braking (n = 17) had significantly lower gait and balance disorder scores and higher normalized-mesencephalic surface areas compared to patients with impaired braking (n = 15). The decreased step length and velocity, characteristic of PD, mainly result from degeneration of central dopaminergic systems. The markedly decreased braking capacity observed in half the PD patients contributes to their gait disorders and postural instability, perhaps as a result of nondopaminergic lesions, possibly at the mesencephalic level.</div></front></TEI><hal api="V3"><titleStmt><title xml:lang="en">Gait and balance disorders in Parkinson's disease: impaired active braking of the fall of centre of gravity.</title><author role="aut"><persName><forename type="first">Nathalie</forename><surname>Chastan</surname></persName><email></email><idno type="halauthor">479008</idno><affiliation ref="#struct-115097"></affiliation></author><author role="aut"><persName><forename type="first">Manh Cuong</forename><surname>Do</surname></persName><email></email><idno type="halauthor">831802</idno></author><author role="aut"><persName><forename type="first">Fabrice</forename><surname>Bonneville</surname></persName><email></email><idno type="halauthor">301219</idno><affiliation ref="#struct-205419"></affiliation></author><author role="aut"><persName><forename type="first">Frédéric</forename><surname>Torny</surname></persName><email></email><idno type="halauthor">598334</idno></author><author role="aut"><persName><forename type="first">Frédéric</forename><surname>Bloch</surname></persName><email></email><idno type="halauthor">380942</idno></author><author role="aut"><persName><forename type="first">G W Max</forename><surname>Westby</surname></persName><email></email><idno type="halauthor">598335</idno></author><author role="aut"><persName><forename type="first">Didier</forename><surname>Dormont</surname></persName><email></email><idno type="halauthor">98507</idno><affiliation ref="#struct-41020"></affiliation><affiliation ref="#struct-218549"></affiliation></author><author role="aut"><persName><forename type="first">Yves</forename><surname>Agid</surname></persName><email></email><idno type="halauthor">217013</idno><affiliation ref="#struct-43171"></affiliation></author><author role="aut"><persName><forename type="first">Marie-Laure</forename><surname>Welter</surname></persName><email></email><idno type="halauthor">214475</idno><affiliation ref="#struct-81470"></affiliation><affiliation ref="#struct-2623"></affiliation><affiliation ref="#struct-5370"></affiliation></author><editor role="depositor"><persName><forename>Olivier</forename><surname>Colliot</surname></persName><email>olivier.colliot@upmc.fr</email></editor></titleStmt><editionStmt><edition n="v1" type="current"><date type="whenSubmitted">2013-03-27 19:07:53</date><date type="whenModified">2013-04-04 16:07:19</date><date type="whenReleased">2013-03-27 19:07:53</date><date type="whenProduced">2009-01-30</date></edition><respStmt><resp>contributor</resp><name key="180860"><persName><forename>Olivier</forename><surname>Colliot</surname></persName><email>olivier.colliot@upmc.fr</email></name></respStmt></editionStmt><publicationStmt><distributor>CCSD</distributor><idno type="halId">hal-00805424</idno><idno type="halUri">https://hal.inria.fr/hal-00805424</idno><idno type="halBibtex">chastan:hal-00805424</idno><idno type="halRefHtml">Movement Disorders, Wiley, 2009, 24 (2), pp.188-95. <10.1002/mds.22269></idno><idno type="halRef">Movement Disorders, Wiley, 2009, 24 (2), pp.188-95. <10.1002/mds.22269></idno></publicationStmt><seriesStmt><idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno><idno type="stamp" n="UPMC">Université Pierre et Marie Curie</idno><idno type="stamp" n="ICM" p="UPMC">Institut du Cerveau et de la Moëlle Epinière</idno></seriesStmt><notesStmt><note type="audience" n="2">International</note><note type="popular" n="0">No</note><note type="peer" n="1">Yes</note></notesStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Gait and balance disorders in Parkinson's disease: impaired active braking of the fall of centre of gravity.</title><author role="aut"><persName><forename type="first">Nathalie</forename><surname>Chastan</surname></persName><idno type="halAuthorId">479008</idno><affiliation ref="#struct-115097"></affiliation></author><author role="aut"><persName><forename type="first">Manh Cuong</forename><surname>Do</surname></persName><idno type="halAuthorId">831802</idno></author><author role="aut"><persName><forename type="first">Fabrice</forename><surname>Bonneville</surname></persName><idno type="halAuthorId">301219</idno><affiliation ref="#struct-205419"></affiliation></author><author role="aut"><persName><forename type="first">Frédéric</forename><surname>Torny</surname></persName><idno type="halAuthorId">598334</idno></author><author role="aut"><persName><forename type="first">Frédéric</forename><surname>Bloch</surname></persName><idno type="halAuthorId">380942</idno></author><author role="aut"><persName><forename type="first">G W Max</forename><surname>Westby</surname></persName><idno type="halAuthorId">598335</idno></author><author role="aut"><persName><forename type="first">Didier</forename><surname>Dormont</surname></persName><idno type="halAuthorId">98507</idno><affiliation ref="#struct-41020"></affiliation><affiliation ref="#struct-218549"></affiliation></author><author role="aut"><persName><forename type="first">Yves</forename><surname>Agid</surname></persName><idno type="halAuthorId">217013</idno><affiliation ref="#struct-43171"></affiliation></author><author role="aut"><persName><forename type="first">Marie-Laure</forename><surname>Welter</surname></persName><idno type="halAuthorId">214475</idno><affiliation ref="#struct-81470"></affiliation><affiliation ref="#struct-2623"></affiliation><affiliation ref="#struct-5370"></affiliation></author></analytic><monogr><idno type="halJournalId" status="VALID">17211</idno><idno type="issn">0885-3185</idno><idno type="eissn">1531-8257</idno><title level="j">Movement Disorders</title><imprint><publisher>Wiley</publisher><biblScope unit="volume">24</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="pp">188-95</biblScope><date type="datePub">2009-01-30</date></imprint></monogr><idno type="doi">10.1002/mds.22269</idno><idno type="pubmed">18973252</idno></biblStruct></sourceDesc><profileDesc><langUsage><language ident="en">English</language></langUsage><textClass><classCode scheme="halDomain" n="info.info-im">Computer Science [cs]/Medical Imaging</classCode><classCode scheme="halTypology" n="ART">Journal articles</classCode></textClass><abstract xml:lang="en">Gait and balance disorders are common in Parkinson's disease (PD), but its pathophysiology is still poorly understood. Step length, antero-posterior, and vertical velocities of the center of gravity (CG) during gait initiation were analyzed in 32 controls and 32 PD patients, with and without levodopa, using a force platform. Brain volumes and mesencephalic surface area were measured in PD patients. During the swing limb period, controls showed a fall in the CG, which was reversed before foot-contact indicating active braking of the CG fall. In PD patients, without levodopa, step length and velocity were significantly reduced and no braking occurred before foot-contact in 22 patients. With levodopa, step length and velocity increased in all patients and 7 patients improved their braking capacity. PD patients with normal braking (n = 17) had significantly lower gait and balance disorder scores and higher normalized-mesencephalic surface areas compared to patients with impaired braking (n = 15). The decreased step length and velocity, characteristic of PD, mainly result from degeneration of central dopaminergic systems. The markedly decreased braking capacity observed in half the PD patients contributes to their gait disorders and postural instability, perhaps as a result of nondopaminergic lesions, possibly at the mesencephalic level.</abstract></profileDesc></hal></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Hal/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000028 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Hal/Corpus/biblio.hfd -nk 000028 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Hal
|étape= Corpus
|type= RBID
|clé= Hal:hal-00805424
|texte= Gait and balance disorders in Parkinson's disease: impaired active braking of the fall of centre of gravity.
}}
| This area was generated with Dilib version V0.6.23. |  |