Myoclonus or tremor in orthostatism: An under‐recognized cause of unsteadiness in Parkinson's disease
Identifieur interne : 000326 ( France/Analysis ); précédent : 000325; suivant : 000327Myoclonus or tremor in orthostatism: An under‐recognized cause of unsteadiness in Parkinson's disease
Auteurs : Smaranda Leu-Semenescu [France] ; Emmanuel Roze [France] ; Marie Vidailhet [France] ; André-Pierre Legrand [France] ; Jean-Marc Trocello [France] ; Valérie Cochen [France] ; Sophie Sangla [France] ; Emmanuelle Apartis [France]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-10-31.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Electromyography, Female, Humans, Hypotension, Orthostatic (etiology), Male, Middle Aged, Muscle Rigidity (etiology), Myoclonus (complications), Parkinson Disease (physiopathology), Parkinson's disease, Retrospective Studies, Tremor (complications), myoclonus, neurophysiology, orthostatic tremor, unsteadiness.
- MESH :
- complications : Myoclonus, Tremor.
- etiology : Hypotension, Orthostatic, Muscle Rigidity.
- physiopathology : Parkinson Disease.
- Adult, Aged, Aged, 80 and over, Electromyography, Female, Humans, Male, Middle Aged, Retrospective Studies.
Abstract
Patients with Parkinson's disease (PD) often complain of unsteadiness. This can occur as the result of various neurological dysfunctions, including changes in postural adjustments, loss of postural reflexes, axial akinesia and rigidity, freezing and/or postural hypotension. In some cases these symptoms remain unexplained, and rare cases of unsteadiness have been attributed to tremor on standing. To delineate this condition, we investigated 11 consecutive PD patients with unexplained unsteadiness because of tremor on standing, seen in our department over a 6‐year period. All the patients had detailed clinical and electrophysiological investigations based on surface polygraphic electromyographic recordings. Four patients had fast orthostatic tremor (13–18 Hz), one had intermediate orthostatic tremor (8–9 Hz), and three had slow orthostatic tremor (4–6 Hz). The remaining 3 patients had orthostatic myoclonus, a condition that has not previously been reported in PD. Patients with fast tremor improved on clonazepam. Patients with slow tremor and myoclonus improved on levodopa and sometimes benefited further when clonazepam was added. These observations show the usefulness of neurophysiological investigations for diagnosing and treating unexplained unsteadiness in Parkinson's disease. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21651
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001925
- to stream Istex, to step Curation: 001925
- to stream Istex, to step Checkpoint: 001837
- to stream PubMed, to step Corpus: 002571
- to stream PubMed, to step Curation: 002571
- to stream PubMed, to step Checkpoint: 002701
- to stream Ncbi, to step Merge: 001D88
- to stream Ncbi, to step Curation: 001D88
- to stream Ncbi, to step Checkpoint: 001D88
- to stream Main, to step Merge: 003C51
- to stream Main, to step Curation: 002D29
- to stream Main, to step Exploration: 002D29
- to stream France, to step Extraction: 000326
Links to Exploration step
ISTEX:78C41FDAD4BF63FC5706D668BF45B1986DA9CA87Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Myoclonus or tremor in orthostatism: An under‐recognized cause of unsteadiness in Parkinson's disease</title>
<author><name sortKey="Leu Emenescu, Smaranda" sort="Leu Emenescu, Smaranda" uniqKey="Leu Emenescu S" first="Smaranda" last="Leu-Semenescu">Smaranda Leu-Semenescu</name>
</author>
<author><name sortKey="Roze, Emmanuel" sort="Roze, Emmanuel" uniqKey="Roze E" first="Emmanuel" last="Roze">Emmanuel Roze</name>
</author>
<author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
</author>
<author><name sortKey="Legrand, Andre Ierre" sort="Legrand, Andre Ierre" uniqKey="Legrand A" first="André-Pierre" last="Legrand">André-Pierre Legrand</name>
</author>
<author><name sortKey="Trocello, Jean Arc" sort="Trocello, Jean Arc" uniqKey="Trocello J" first="Jean-Marc" last="Trocello">Jean-Marc Trocello</name>
</author>
<author><name sortKey="Cochen, Valerie" sort="Cochen, Valerie" uniqKey="Cochen V" first="Valérie" last="Cochen">Valérie Cochen</name>
</author>
<author><name sortKey="Sangla, Sophie" sort="Sangla, Sophie" uniqKey="Sangla S" first="Sophie" last="Sangla">Sophie Sangla</name>
</author>
<author><name sortKey="Apartis, Emmanuelle" sort="Apartis, Emmanuelle" uniqKey="Apartis E" first="Emmanuelle" last="Apartis">Emmanuelle Apartis</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:78C41FDAD4BF63FC5706D668BF45B1986DA9CA87</idno>
<date when="2007" year="2007">2007</date>
<idno type="doi">10.1002/mds.21651</idno>
<idno type="url">https://api.istex.fr/document/78C41FDAD4BF63FC5706D668BF45B1986DA9CA87/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001925</idno>
<idno type="wicri:Area/Istex/Curation">001925</idno>
<idno type="wicri:Area/Istex/Checkpoint">001837</idno>
<idno type="wicri:doubleKey">0885-3185:2007:Leu Emenescu S:myoclonus:or:tremor</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:17674413</idno>
<idno type="wicri:Area/PubMed/Corpus">002571</idno>
<idno type="wicri:Area/PubMed/Curation">002571</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002701</idno>
<idno type="wicri:Area/Ncbi/Merge">001D88</idno>
<idno type="wicri:Area/Ncbi/Curation">001D88</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001D88</idno>
<idno type="wicri:doubleKey">0885-3185:2007:Leu Semenescu S:myoclonus:or:tremor</idno>
<idno type="wicri:Area/Main/Merge">003C51</idno>
<idno type="wicri:Area/Main/Curation">002D29</idno>
<idno type="wicri:Area/Main/Exploration">002D29</idno>
<idno type="wicri:Area/France/Extraction">000326</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Myoclonus or tremor in orthostatism: An under‐recognized cause of unsteadiness in Parkinson's disease</title>
<author><name sortKey="Leu Emenescu, Smaranda" sort="Leu Emenescu, Smaranda" uniqKey="Leu Emenescu S" first="Smaranda" last="Leu-Semenescu">Smaranda Leu-Semenescu</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Neurology, Saint‐Antoine Hospital, AP‐HP, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Roze, Emmanuel" sort="Roze, Emmanuel" uniqKey="Roze E" first="Emmanuel" last="Roze">Emmanuel Roze</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Neurology, Saint‐Antoine Hospital, AP‐HP, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>CNRS UMR 7102, Pierre et Marie Curie–Paris 6 University, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Neurology, Saint‐Antoine Hospital, AP‐HP, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U679, Pierre et Marie Curie–Paris 6 University, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Legrand, Andre Ierre" sort="Legrand, Andre Ierre" uniqKey="Legrand A" first="André-Pierre" last="Legrand">André-Pierre Legrand</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Quantum Physics Laboratory, ESPCI, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Trocello, Jean Arc" sort="Trocello, Jean Arc" uniqKey="Trocello J" first="Jean-Marc" last="Trocello">Jean-Marc Trocello</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Neurology, Saint‐Antoine Hospital, AP‐HP, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Physiology, Saint‐Antoine Hospital, AP‐HP, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U732, Pierre et Marie Curie–Paris 6 University, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Cochen, Valerie" sort="Cochen, Valerie" uniqKey="Cochen V" first="Valérie" last="Cochen">Valérie Cochen</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Neurology, Saint‐Antoine Hospital, AP‐HP, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U679, Pierre et Marie Curie–Paris 6 University, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sangla, Sophie" sort="Sangla, Sophie" uniqKey="Sangla S" first="Sophie" last="Sangla">Sophie Sangla</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Neurology, Saint‐Antoine Hospital, AP‐HP, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Apartis, Emmanuelle" sort="Apartis, Emmanuelle" uniqKey="Apartis E" first="Emmanuelle" last="Apartis">Emmanuelle Apartis</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Physiology, Saint‐Antoine Hospital, AP‐HP, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U732, Pierre et Marie Curie–Paris 6 University, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2007-10-31">2007-10-31</date>
<biblScope unit="vol">22</biblScope>
<biblScope unit="issue">14</biblScope>
<biblScope unit="page" from="2063">2063</biblScope>
<biblScope unit="page" to="2069">2069</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">78C41FDAD4BF63FC5706D668BF45B1986DA9CA87</idno>
<idno type="DOI">10.1002/mds.21651</idno>
<idno type="ArticleID">MDS21651</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Electromyography</term>
<term>Female</term>
<term>Humans</term>
<term>Hypotension, Orthostatic (etiology)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Muscle Rigidity (etiology)</term>
<term>Myoclonus (complications)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson's disease</term>
<term>Retrospective Studies</term>
<term>Tremor (complications)</term>
<term>myoclonus</term>
<term>neurophysiology</term>
<term>orthostatic tremor</term>
<term>unsteadiness</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Myoclonus</term>
<term>Tremor</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Hypotension, Orthostatic</term>
<term>Muscle Rigidity</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Electromyography</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Retrospective Studies</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Patients with Parkinson's disease (PD) often complain of unsteadiness. This can occur as the result of various neurological dysfunctions, including changes in postural adjustments, loss of postural reflexes, axial akinesia and rigidity, freezing and/or postural hypotension. In some cases these symptoms remain unexplained, and rare cases of unsteadiness have been attributed to tremor on standing. To delineate this condition, we investigated 11 consecutive PD patients with unexplained unsteadiness because of tremor on standing, seen in our department over a 6‐year period. All the patients had detailed clinical and electrophysiological investigations based on surface polygraphic electromyographic recordings. Four patients had fast orthostatic tremor (13–18 Hz), one had intermediate orthostatic tremor (8–9 Hz), and three had slow orthostatic tremor (4–6 Hz). The remaining 3 patients had orthostatic myoclonus, a condition that has not previously been reported in PD. Patients with fast tremor improved on clonazepam. Patients with slow tremor and myoclonus improved on levodopa and sometimes benefited further when clonazepam was added. These observations show the usefulness of neurophysiological investigations for diagnosing and treating unexplained unsteadiness in Parkinson's disease. © 2007 Movement Disorder Society</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
</country>
<settlement><li>Paris</li>
</settlement>
</list>
<tree><country name="France"><noRegion><name sortKey="Leu Emenescu, Smaranda" sort="Leu Emenescu, Smaranda" uniqKey="Leu Emenescu S" first="Smaranda" last="Leu-Semenescu">Smaranda Leu-Semenescu</name>
</noRegion>
<name sortKey="Apartis, Emmanuelle" sort="Apartis, Emmanuelle" uniqKey="Apartis E" first="Emmanuelle" last="Apartis">Emmanuelle Apartis</name>
<name sortKey="Apartis, Emmanuelle" sort="Apartis, Emmanuelle" uniqKey="Apartis E" first="Emmanuelle" last="Apartis">Emmanuelle Apartis</name>
<name sortKey="Cochen, Valerie" sort="Cochen, Valerie" uniqKey="Cochen V" first="Valérie" last="Cochen">Valérie Cochen</name>
<name sortKey="Cochen, Valerie" sort="Cochen, Valerie" uniqKey="Cochen V" first="Valérie" last="Cochen">Valérie Cochen</name>
<name sortKey="Legrand, Andre Ierre" sort="Legrand, Andre Ierre" uniqKey="Legrand A" first="André-Pierre" last="Legrand">André-Pierre Legrand</name>
<name sortKey="Roze, Emmanuel" sort="Roze, Emmanuel" uniqKey="Roze E" first="Emmanuel" last="Roze">Emmanuel Roze</name>
<name sortKey="Roze, Emmanuel" sort="Roze, Emmanuel" uniqKey="Roze E" first="Emmanuel" last="Roze">Emmanuel Roze</name>
<name sortKey="Sangla, Sophie" sort="Sangla, Sophie" uniqKey="Sangla S" first="Sophie" last="Sangla">Sophie Sangla</name>
<name sortKey="Trocello, Jean Arc" sort="Trocello, Jean Arc" uniqKey="Trocello J" first="Jean-Marc" last="Trocello">Jean-Marc Trocello</name>
<name sortKey="Trocello, Jean Arc" sort="Trocello, Jean Arc" uniqKey="Trocello J" first="Jean-Marc" last="Trocello">Jean-Marc Trocello</name>
<name sortKey="Trocello, Jean Arc" sort="Trocello, Jean Arc" uniqKey="Trocello J" first="Jean-Marc" last="Trocello">Jean-Marc Trocello</name>
<name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
<name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/France/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000326 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/France/Analysis/biblio.hfd -nk 000326 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= France |étape= Analysis |type= RBID |clé= ISTEX:78C41FDAD4BF63FC5706D668BF45B1986DA9CA87 |texte= Myoclonus or tremor in orthostatism: An under‐recognized cause of unsteadiness in Parkinson's disease }}
This area was generated with Dilib version V0.6.23. |