High production of interleukin-10 and interferon-γ in influenza-associated MERS in the early phase.
Identifieur interne : 001D62 ( PubMed/Curation ); précédent : 001D61; suivant : 001D63High production of interleukin-10 and interferon-γ in influenza-associated MERS in the early phase.
Auteurs : Shinichiro Morichi [Japon] ; Hisashi Kawashima ; Hiroaki Ioi ; Gaku Yamanaka ; Yasuyo Kashiwagi ; Akinori HoshikaSource :
- Pediatrics international : official journal of the Japan Pediatric Society [ 1442-200X ] ; 2012.
Descripteurs français
- KwdFr :
- MESH :
- biosynthèse : Interféron gamma, Interleukine-10.
- métabolisme : Encéphalite virale, Grippe humaine, Maladies de la rate.
- virologie : Maladies de la rate.
- Enfant, Facteurs temps, Grippe humaine, Humains, Mâle.
English descriptors
- KwdEn :
- MESH :
- chemical , biosynthesis : Interferon-gamma, Interleukin-10.
- complications : Influenza, Human.
- metabolism : Encephalitis, Viral, Influenza, Human, Splenic Diseases.
- virology : Splenic Diseases.
- Child, Humans, Male, Time Factors.
Abstract
Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) occurs in various diseases and pathologies, and the clinical symptoms are not consistent with the impaired region. The mechanism of the region specificity is unclear. We investigated the cytokine profiling in cerebrospinal fluid (CSF) and serum obtained from a child with MERS during influenza infection, and compared them with those of serious another serious type of influenza-associated encephalopathy. There was no elevation of Interleukin (IL)-1β, which induces convulsion. The inhibitory cytokines of IL-10 and IFN-γ were elevated in the early phase in CSF. Comparing them with other patients, the elevation of the cytokine levels were generally mild. Considering that the prognosis of this MERS case was favorable and high levels of inhibitory cytokines including IL-10 and IFN-γ might work to localize the lesion and to prevent sequelae.
DOI: 10.1111/j.1442-200X.2011.03483.x
PubMed: 22830540
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001D62
Links to Exploration step
pubmed:22830540Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">High production of interleukin-10 and interferon-γ in influenza-associated MERS in the early phase.</title>
<author><name sortKey="Morichi, Shinichiro" sort="Morichi, Shinichiro" uniqKey="Morichi S" first="Shinichiro" last="Morichi">Shinichiro Morichi</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Tokyo Medical University, Tokyo, Japan. shinichiro-m@hotmail.co.jp</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Pediatrics, Tokyo Medical University, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kawashima, Hisashi" sort="Kawashima, Hisashi" uniqKey="Kawashima H" first="Hisashi" last="Kawashima">Hisashi Kawashima</name>
</author>
<author><name sortKey="Ioi, Hiroaki" sort="Ioi, Hiroaki" uniqKey="Ioi H" first="Hiroaki" last="Ioi">Hiroaki Ioi</name>
</author>
<author><name sortKey="Yamanaka, Gaku" sort="Yamanaka, Gaku" uniqKey="Yamanaka G" first="Gaku" last="Yamanaka">Gaku Yamanaka</name>
</author>
<author><name sortKey="Kashiwagi, Yasuyo" sort="Kashiwagi, Yasuyo" uniqKey="Kashiwagi Y" first="Yasuyo" last="Kashiwagi">Yasuyo Kashiwagi</name>
</author>
<author><name sortKey="Hoshika, Akinori" sort="Hoshika, Akinori" uniqKey="Hoshika A" first="Akinori" last="Hoshika">Akinori Hoshika</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2012">2012</date>
<idno type="RBID">pubmed:22830540</idno>
<idno type="pmid">22830540</idno>
<idno type="doi">10.1111/j.1442-200X.2011.03483.x</idno>
<idno type="wicri:Area/PubMed/Corpus">001D62</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001D62</idno>
<idno type="wicri:Area/PubMed/Curation">001D62</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001D62</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">High production of interleukin-10 and interferon-γ in influenza-associated MERS in the early phase.</title>
<author><name sortKey="Morichi, Shinichiro" sort="Morichi, Shinichiro" uniqKey="Morichi S" first="Shinichiro" last="Morichi">Shinichiro Morichi</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Tokyo Medical University, Tokyo, Japan. shinichiro-m@hotmail.co.jp</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Pediatrics, Tokyo Medical University, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kawashima, Hisashi" sort="Kawashima, Hisashi" uniqKey="Kawashima H" first="Hisashi" last="Kawashima">Hisashi Kawashima</name>
</author>
<author><name sortKey="Ioi, Hiroaki" sort="Ioi, Hiroaki" uniqKey="Ioi H" first="Hiroaki" last="Ioi">Hiroaki Ioi</name>
</author>
<author><name sortKey="Yamanaka, Gaku" sort="Yamanaka, Gaku" uniqKey="Yamanaka G" first="Gaku" last="Yamanaka">Gaku Yamanaka</name>
</author>
<author><name sortKey="Kashiwagi, Yasuyo" sort="Kashiwagi, Yasuyo" uniqKey="Kashiwagi Y" first="Yasuyo" last="Kashiwagi">Yasuyo Kashiwagi</name>
</author>
<author><name sortKey="Hoshika, Akinori" sort="Hoshika, Akinori" uniqKey="Hoshika A" first="Akinori" last="Hoshika">Akinori Hoshika</name>
</author>
</analytic>
<series><title level="j">Pediatrics international : official journal of the Japan Pediatric Society</title>
<idno type="eISSN">1442-200X</idno>
<imprint><date when="2012" type="published">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Child</term>
<term>Encephalitis, Viral (metabolism)</term>
<term>Humans</term>
<term>Influenza, Human (complications)</term>
<term>Influenza, Human (metabolism)</term>
<term>Interferon-gamma (biosynthesis)</term>
<term>Interleukin-10 (biosynthesis)</term>
<term>Male</term>
<term>Splenic Diseases (metabolism)</term>
<term>Splenic Diseases (virology)</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Encéphalite virale (métabolisme)</term>
<term>Enfant</term>
<term>Facteurs temps</term>
<term>Grippe humaine ()</term>
<term>Grippe humaine (métabolisme)</term>
<term>Humains</term>
<term>Interféron gamma (biosynthèse)</term>
<term>Interleukine-10 (biosynthèse)</term>
<term>Maladies de la rate (métabolisme)</term>
<term>Maladies de la rate (virologie)</term>
<term>Mâle</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Interferon-gamma</term>
<term>Interleukin-10</term>
</keywords>
<keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr"><term>Interféron gamma</term>
<term>Interleukine-10</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Encephalitis, Viral</term>
<term>Influenza, Human</term>
<term>Splenic Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Encéphalite virale</term>
<term>Grippe humaine</term>
<term>Maladies de la rate</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Maladies de la rate</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Splenic Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Child</term>
<term>Humans</term>
<term>Male</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Enfant</term>
<term>Facteurs temps</term>
<term>Grippe humaine</term>
<term>Humains</term>
<term>Mâle</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) occurs in various diseases and pathologies, and the clinical symptoms are not consistent with the impaired region. The mechanism of the region specificity is unclear. We investigated the cytokine profiling in cerebrospinal fluid (CSF) and serum obtained from a child with MERS during influenza infection, and compared them with those of serious another serious type of influenza-associated encephalopathy. There was no elevation of Interleukin (IL)-1β, which induces convulsion. The inhibitory cytokines of IL-10 and IFN-γ were elevated in the early phase in CSF. Comparing them with other patients, the elevation of the cytokine levels were generally mild. Considering that the prognosis of this MERS case was favorable and high levels of inhibitory cytokines including IL-10 and IFN-γ might work to localize the lesion and to prevent sequelae.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">22830540</PMID>
<DateCompleted><Year>2012</Year>
<Month>12</Month>
<Day>10</Day>
</DateCompleted>
<DateRevised><Year>2016</Year>
<Month>05</Month>
<Day>11</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1442-200X</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>54</Volume>
<Issue>4</Issue>
<PubDate><Year>2012</Year>
<Month>Aug</Month>
</PubDate>
</JournalIssue>
<Title>Pediatrics international : official journal of the Japan Pediatric Society</Title>
<ISOAbbreviation>Pediatr Int</ISOAbbreviation>
</Journal>
<ArticleTitle>High production of interleukin-10 and interferon-γ in influenza-associated MERS in the early phase.</ArticleTitle>
<Pagination><MedlinePgn>536-8</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1111/j.1442-200X.2011.03483.x</ELocationID>
<Abstract><AbstractText>Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) occurs in various diseases and pathologies, and the clinical symptoms are not consistent with the impaired region. The mechanism of the region specificity is unclear. We investigated the cytokine profiling in cerebrospinal fluid (CSF) and serum obtained from a child with MERS during influenza infection, and compared them with those of serious another serious type of influenza-associated encephalopathy. There was no elevation of Interleukin (IL)-1β, which induces convulsion. The inhibitory cytokines of IL-10 and IFN-γ were elevated in the early phase in CSF. Comparing them with other patients, the elevation of the cytokine levels were generally mild. Considering that the prognosis of this MERS case was favorable and high levels of inhibitory cytokines including IL-10 and IFN-γ might work to localize the lesion and to prevent sequelae.</AbstractText>
<CopyrightInformation>© 2012 The Authors. Pediatrics International © 2012 Japan Pediatric Society.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Morichi</LastName>
<ForeName>Shinichiro</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Tokyo Medical University, Tokyo, Japan. shinichiro-m@hotmail.co.jp</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kawashima</LastName>
<ForeName>Hisashi</ForeName>
<Initials>H</Initials>
</Author>
<Author ValidYN="Y"><LastName>Ioi</LastName>
<ForeName>Hiroaki</ForeName>
<Initials>H</Initials>
</Author>
<Author ValidYN="Y"><LastName>Yamanaka</LastName>
<ForeName>Gaku</ForeName>
<Initials>G</Initials>
</Author>
<Author ValidYN="Y"><LastName>Kashiwagi</LastName>
<ForeName>Yasuyo</ForeName>
<Initials>Y</Initials>
</Author>
<Author ValidYN="Y"><LastName>Hoshika</LastName>
<ForeName>Akinori</ForeName>
<Initials>A</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>Australia</Country>
<MedlineTA>Pediatr Int</MedlineTA>
<NlmUniqueID>100886002</NlmUniqueID>
<ISSNLinking>1328-8067</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>130068-27-8</RegistryNumber>
<NameOfSubstance UI="D016753">Interleukin-10</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>82115-62-6</RegistryNumber>
<NameOfSubstance UI="D007371">Interferon-gamma</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018792" MajorTopicYN="N">Encephalitis, Viral</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007371" MajorTopicYN="N">Interferon-gamma</DescriptorName>
<QualifierName UI="Q000096" MajorTopicYN="Y">biosynthesis</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016753" MajorTopicYN="N">Interleukin-10</DescriptorName>
<QualifierName UI="Q000096" MajorTopicYN="Y">biosynthesis</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013158" MajorTopicYN="N">Splenic Diseases</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2012</Year>
<Month>7</Month>
<Day>27</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2012</Year>
<Month>7</Month>
<Day>27</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2012</Year>
<Month>12</Month>
<Day>12</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">22830540</ArticleId>
<ArticleId IdType="doi">10.1111/j.1442-200X.2011.03483.x</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001D62 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 001D62 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= MersV1 |flux= PubMed |étape= Curation |type= RBID |clé= pubmed:22830540 |texte= High production of interleukin-10 and interferon-γ in influenza-associated MERS in the early phase. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:22830540" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \ | NlmPubMed2Wicri -a MersV1
This area was generated with Dilib version V0.6.33. |